{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:18:24Z","timestamp":1792682304325,"version":"4.5.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.anai.2016.09.426","type":"journal-article","created":{"date-parts":[[2016,10,24]],"date-time":"2016-10-24T05:30:34Z","timestamp":1477287034000},"page":"527-534","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Urtica dioica pollen allergy"],"prefix":"10.1016","volume":"117","author":[{"given":"Angelica","family":"Tiotiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Brazdova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyril","family":"Long\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrice","family":"Gallet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Morisset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Leduc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Hilger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9dric","family":"Broussard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9my","family":"Couderc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Pierre","family":"Sutra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"S\u00e9n\u00e9chal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Poncet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anai.2016.09.426_bib1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s00431-010-1327-z","article-title":"Urticaria due to Urtica dioica in a neonate","volume":"170","author":"Uslu","year":"2011","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.anai.2016.09.426_bib2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ctim.2003.12.001","article-title":"Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema","volume":"12","author":"Caliskaner","year":"2004","journal-title":"Complement Ther Med"},{"key":"10.1016\/j.anai.2016.09.426_bib3","first-page":"26","article-title":"Hay fever plants in Oklahoma","volume":"45","author":"Levetin","year":"1980","journal-title":"Ann Allergy"},{"key":"10.1016\/j.anai.2016.09.426_bib4","series-title":"Airborne and Allergenic Pollen of North America","author":"Lewis","year":"1983"},{"key":"10.1016\/j.anai.2016.09.426_bib5","article-title":"Regional Allergy of the United States, Southern California","volume":"Vol. 356","author":"Piness","year":"1955"},{"key":"10.1016\/j.anai.2016.09.426_bib6","first-page":"157","article-title":"Associations among pollen sensitizations from different botanical species in patients living in the northern area of Madrid","volume":"17","author":"Belver","year":"2007","journal-title":"J\u00a0Investig Allergol Clin Immunol"},{"issue":"suppl 1","key":"10.1016\/j.anai.2016.09.426_bib7","first-page":"205","article-title":"Par j 2 as a Parietaria sensitisation marker allergen: definition of its use in epidemiology and diagnosis","volume":"17","author":"Mari","year":"2005","journal-title":"Allergy Clin Immunol Int"},{"key":"10.1016\/j.anai.2016.09.426_bib8","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/j.1365-2222.2011.03938.x","article-title":"Characterization of a Par j 1\/Par j 2 mutant hybrid with reduced allergenicity for immunotherapy of Parietaria allergy","volume":"42","author":"Bonura","year":"2012","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.anai.2016.09.426_bib9","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ymeth.2013.06.014","article-title":"Allergens of weed pollen: an overview on recombinant and natural molecules","volume":"66","author":"Gadermaier","year":"2014","journal-title":"Methods"},{"key":"10.1016\/j.anai.2016.09.426_bib10","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.molimm.2013.09.004","article-title":"Cloning, expression in E.\u00a0coli and immunological characterization of Par j 3.0201, a Parietaria pollen profilin variant","volume":"57","author":"Bonura","year":"2014","journal-title":"Mol Immunol"},{"key":"10.1016\/j.anai.2016.09.426_bib11","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1016\/j.molimm.2008.01.009","article-title":"Isolation, expression and immunological characterization of a calcium-binding protein from Parietaria pollen","volume":"45","author":"Bonura","year":"2008","journal-title":"Mol Immunol"},{"key":"10.1016\/j.anai.2016.09.426_bib12","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1365-2222.1986.tb01954.x","article-title":"Allergy in the Mediterranean area, II: cross-allergenicity among Urticaceae pollens (Parietaria and Urtica)","volume":"16","author":"Bousquet","year":"1986","journal-title":"Clin Allergy"},{"key":"10.1016\/j.anai.2016.09.426_bib13","first-page":"649","article-title":"Ramie (Boehmeria nivea) pollen-induced bronchial asthma and allergenic cross-reactivity of ramie and Parietaria","volume":"42","author":"Miura","year":"1993","journal-title":"Arerugi"},{"key":"10.1016\/j.anai.2016.09.426_bib14","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1385\/CRIAI:21:2-3:261","article-title":"Common allergenic pollens, fungi, animals, and arthropods","volume":"21","author":"Esch","year":"2001","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.anai.2016.09.426_bib15","first-page":"219","article-title":"Volumetric counts of pollen grains at Cardiff, 1954-1957","volume":"30","author":"Hyde","year":"1959","journal-title":"J\u00a0Allergy"},{"key":"10.1016\/j.anai.2016.09.426_bib16","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1055\/s-2006-960881","article-title":"Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis","volume":"56","author":"Mittman","year":"1990","journal-title":"Planta Med"},{"key":"10.1016\/j.anai.2016.09.426_bib17","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.taap.2007.10.005","article-title":"Risks and benefits of commonly used herbal medicines in Mexico","volume":"227","author":"Rodriguez-Fragoso","year":"2008","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.anai.2016.09.426_bib18","doi-asserted-by":"crossref","first-page":"938751","DOI":"10.1155\/2013\/938751","article-title":"Complementary therapies in allergic rhinitis","volume":"2013","author":"Sayin","year":"2013","journal-title":"ISRN Allergy"},{"key":"10.1016\/j.anai.2016.09.426_bib19","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/2045-7022-3-3","article-title":"The skin prick test: European standards","volume":"3","author":"Heinzerling","year":"2013","journal-title":"Clin Transl Allergy"},{"key":"10.1016\/j.anai.2016.09.426_bib20","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1097\/01.MLG.0000149682.56426.6B","article-title":"Nasal provocation testing as an international standard for evaluation of allergic and nonallergic rhinitis","volume":"115","author":"Gosepath","year":"2005","journal-title":"Laryngoscope"},{"issue":"suppl 86","key":"10.1016\/j.anai.2016.09.426_bib21","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1398-9995.2007.01620.x","article-title":"Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)","volume":"63","author":"Bousquet","year":"2008","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.09.426_bib22","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/WOX.0b013e3181eb3525","article-title":"IgE reactivity to common cypress (C.\u00a0sempervirens) pollen extracts: evidence for novel allergens","volume":"3","author":"Shahali","year":"2010","journal-title":"World Allergy Organ J"},{"key":"10.1016\/j.anai.2016.09.426_bib23","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1111\/j.1742-4658.2012.08536.x","article-title":"Differential IgE sensitization to cypress pollen associated to a basic allergen of 14 kDa","volume":"279","author":"Shahali","year":"2012","journal-title":"FEBS J"},{"key":"10.1016\/j.anai.2016.09.426_bib24","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1111\/j.1398-9995.2009.02231.x","article-title":"Evaluation of ash pollen sensitization pattern using proteomic approach with individual sera from allergic patients","volume":"65","author":"Poncet","year":"2010","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.09.426_bib25","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1021\/pr200923f","article-title":"Proteomic analysis of major and minor allergens from isolated pollen cytoplasmic granules","volume":"11","author":"Abou Chakra","year":"2012","journal-title":"J\u00a0Proteome Res"},{"key":"10.1016\/j.anai.2016.09.426_bib26","doi-asserted-by":"crossref","first-page":"e0154264","DOI":"10.1371\/journal.pone.0154264","article-title":"The shell of the invasive bivalve species Dreissena polymorpha: biochemical, elemental and textural investigations","volume":"11","author":"Immel","year":"2016","journal-title":"PLoS ONE"},{"key":"10.1016\/j.anai.2016.09.426_bib27","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S1081-1206(10)60799-5","article-title":"Allergenic proteins in Urtica dioica, a member of the Urticaceae allergenic family","volume":"97","author":"Vega-Maray","year":"2006","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.09.426_bib28","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/prot.10571","article-title":"Crystal structure of osmotin, a plant antifungal protein","volume":"54","author":"Min","year":"2004","journal-title":"Proteins"},{"key":"10.1016\/j.anai.2016.09.426_bib29","doi-asserted-by":"crossref","first-page":"9990","DOI":"10.1021\/jf202265d","article-title":"Allergenicity assessment of osmotin, a pathogenesis-related protein, used for transgenic crops","volume":"59","author":"Sharma","year":"2011","journal-title":"J\u00a0Agric Food Chem"},{"key":"10.1016\/j.anai.2016.09.426_bib30","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1046\/j.1398-9995.2003.00363.x","article-title":"Cloning and expression of a major allergen from Cupressus arizonica pollen, Cup a 3, a PR-5 protein expressed under polluted environment","volume":"59","author":"Cortegano","year":"2004","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.09.426_bib31","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1081-1206(10)60836-8","article-title":"Effects of air pollution on Cup a 3 allergen in Cupressus arizonica pollen grains","volume":"101","author":"Suarez-Cervera","year":"2008","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.09.426_bib32","doi-asserted-by":"crossref","first-page":"e44088","DOI":"10.1371\/journal.pone.0044088","article-title":"The involvement of thaumatin-like proteins in plant food cross-reactivity: a multicenter study using a specific protein microarray","volume":"7","author":"Palacin","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.anai.2016.09.426_bib33","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1159\/000053670","article-title":"cDna cloning and characterization of a cross-reactive birch pollen allergen: identification as a pectin esterase","volume":"124","author":"Mahler","year":"2001","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.anai.2016.09.426_bib34","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.jaci.2013.10.061","article-title":"Ash pollen immunoproteomics: Identification, immunologic characterization, and sequencing of 6 new allergens","volume":"133","author":"Mas","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.09.426_bib35","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/prot.21681","article-title":"The peculiar structural features of kiwi fruit pectin methylesterase: amino acid sequence, oligosaccharides structure, and modeling of the interaction with its natural proteinaceous inhibitor","volume":"71","author":"Ciardiello","year":"2008","journal-title":"Proteins"},{"key":"10.1016\/j.anai.2016.09.426_bib36","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1105\/tpc.104.028886","article-title":"Structural basis for the interaction between pectin methylesterase and a specific inhibitor protein","volume":"17","author":"Di Matteo","year":"2005","journal-title":"Plant Cell"},{"key":"10.1016\/j.anai.2016.09.426_bib37","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/0161-5890(82)90263-2","article-title":"Allergenic cross-reactivity of cytochromes c of Kentucky bluegrass and perennial ryegrass pollens","volume":"19","author":"Ekramoddoullah","year":"1982","journal-title":"Mol Immunol"},{"key":"10.1016\/j.anai.2016.09.426_bib38","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s11033-010-0078-2","article-title":"Identification of methionine synthase (Sal k 3), as a novel allergen of Salsola kali pollen","volume":"38","author":"Assarehzadegan","year":"2011","journal-title":"Mol Biol Rep"},{"key":"10.1016\/j.anai.2016.09.426_bib39","doi-asserted-by":"crossref","first-page":"284","DOI":"10.11604\/pamj.2014.19.284.4654","article-title":"High IgE sensitization to maize and rice pollen in the highlands of Madagascar","volume":"19","author":"Ramavovololona","year":"2014","journal-title":"Pan Afr Med J"},{"key":"10.1016\/j.anai.2016.09.426_bib40","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1016\/j.jprot.2010.03.002","article-title":"In-depth exploration of Hevea brasiliensis latex proteome and \u201chidden allergens\u201d via combinatorial peptide ligand libraries","volume":"73","author":"D'Amato","year":"2010","journal-title":"J\u00a0Proteomics"},{"key":"10.1016\/j.anai.2016.09.426_bib41","doi-asserted-by":"crossref","first-page":"5517","DOI":"10.1021\/pr100604x","article-title":"Immuno-reactive molecules identified from the secreted proteome of Aspergillus fumigatus","volume":"9","author":"Singh","year":"2010","journal-title":"J\u00a0Proteome Res"},{"key":"10.1016\/j.anai.2016.09.426_bib42","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1002\/elps.201200643","article-title":"Proteomic analysis of Lycium barbarum (Goji) fruit via combinatorial peptide ligand libraries","volume":"34","author":"D'Amato","year":"2013","journal-title":"Electrophoresis"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120616310535?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120616310535?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:15:45Z","timestamp":1761052545000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1081120616310535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S1081120616310535"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2016.09.426","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Urtica dioica pollen allergy","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2016.09.426","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}