{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T12:58:38Z","timestamp":1752670718173,"version":"3.40.5"},"reference-count":48,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"am","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","annallergy.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.anai.2024.05.002","type":"journal-article","created":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T00:13:37Z","timestamp":1715472817000},"page":"194-202.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Frequencies and predictors of subcutaneous and intraosseous injection with 4 epinephrine autoinjector devices"],"prefix":"10.1016","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8806-6623","authenticated-orcid":false,"given":"S\u00e9bastien","family":"Lefevre","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Goetz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Hennequin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinka","family":"Zevering","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Dinot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"suppl 1","key":"10.1016\/j.anai.2024.05.002_bib0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1710-1492-7-S1-I1","article-title":"Anaphylaxis","volume":"7","author":"Kim","year":"2011","journal-title":"Allergy Asthma Clin Immunol"},{"issue":"8","key":"10.1016\/j.anai.2024.05.002_bib0002","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1046\/j.1365-2222.2000.00864.x","article-title":"Lessons for management of anaphylaxis from a study of fatal reactions","volume":"30","author":"Pumphrey","year":"2000","journal-title":"Clin Exp Allergy"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0003","first-page":"1","article-title":"2015 update of the evidence base: World Allergy Organization anaphylaxis guidelines","volume":"8","author":"Simons","year":"2015","journal-title":"World Allergy Organ J"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0004","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jada.2010.10.033","article-title":"Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report","volume":"111","author":"Boyce","year":"2011","journal-title":"J Am Diet Assoc"},{"issue":"4","key":"10.1016\/j.anai.2024.05.002_bib0005","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.anai.2017.07.030","article-title":"Contemporary issues in anaphylaxis and the evolution of epinephrine autoinjectors: what will the future bring?","volume":"119","author":"Greenberger","year":"2017","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"4","key":"10.1016\/j.anai.2024.05.002_bib0006","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.jaci.2007.01.021","article-title":"Further fatal allergic reactions to food in the United Kingdom, 1999-2006","volume":"119","author":"Pumphrey","year":"2007","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0007","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1398-9995.2010.02450.x","article-title":"What are the \u201cideal\u201d features of an adrenaline (epinephrine) auto-injector in the treatment of anaphylaxis?","volume":"66","author":"Frew","year":"2011","journal-title":"Allergy Eur J Allergy Clin Immunol"},{"issue":"4","key":"10.1016\/j.anai.2024.05.002_bib0008","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/ACI.0000000000000283","article-title":"Epinephrine auto-injector needle length: what is the ideal length?","volume":"16","author":"Song","year":"2016","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2024.05.002_bib0009","unstructured":"Ferrandiz R. Cartridge vs syringe auto-injectors: a misleading discussion. Accessed May 1, 2022. Available at: https:\/\/www.emerade.com\/hcp\/articles\/cartridge-vs-syringe-auto-injectors"},{"key":"10.1016\/j.anai.2024.05.002_bib0010","series-title":"EAACI Congress","article-title":"Tissue distribution of dye marker following autoinjector use","author":"Pumphrey","year":"2014"},{"key":"10.1016\/j.anai.2024.05.002_bib0011","doi-asserted-by":"crossref","first-page":"257","DOI":"10.2147\/MDER.S83406","article-title":"Comparison of drug delivery with autoinjector versus manual prefilled syringe and between three different autoinjector devices administered in pig thigh","volume":"9","author":"Hill","year":"2016","journal-title":"Med Devices Evid Res"},{"issue":"5","key":"10.1016\/j.anai.2024.05.002_bib0012","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.anai.2018.07.022","article-title":"Pressure, trigger forces, and epinephrine auto-injectors","volume":"121","author":"Brown","year":"2018","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"2","key":"10.1016\/j.anai.2024.05.002_bib0013","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.anai.2013.05.022","article-title":"Delivery depth of epinephrine by auto-injector into the subcutaneous tissue of pig","volume":"111","author":"Song","year":"2013","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"5","key":"10.1016\/j.anai.2024.05.002_bib0014","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.anai.2018.09.456","article-title":"Authors\u2019 response","volume":"121","author":"Dreborg","year":"2018","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2024.05.002_bib0015","doi-asserted-by":"crossref","first-page":"39","DOI":"10.2147\/JAA.S33688","article-title":"Comparison of the robustness and functionality of three adrenaline auto-injectors","volume":"5","author":"Schwirtz","year":"2012","journal-title":"J Asthma Allergy"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0016","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.anai.2019.04.027","article-title":"Implications of variation of epinephrine auto-injector needle length","volume":"123","author":"Dreborg","year":"2019","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0017","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0091-6749(98)70190-3","article-title":"Epinephrine absorption in children with a history of anaphylaxis","volume":"101","author":"Simons","year":"1998","journal-title":"J Allergy Clin Immunol"},{"issue":"5","key":"10.1016\/j.anai.2024.05.002_bib0018","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1067\/mai.2001.119409","article-title":"Epinephrine absorption in adults: intramuscular versus subcutaneous injection","volume":"108","author":"Simons","year":"2001","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0019","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13223-021-00511-y","article-title":"The pharmacokinetics of epinephrine\/adrenaline autoinjectors","volume":"17","author":"Dreborg","year":"2021","journal-title":"Allergy Asthma Clin Immunol"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0020","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/cea.14055","article-title":"Pharmacokinetics of adrenaline autoinjectors","volume":"52","author":"Turner","year":"2022","journal-title":"Clin Exp Allergy"},{"issue":"2","key":"10.1016\/j.anai.2024.05.002_bib0021","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.anai.2013.06.002","article-title":"Bioavailability of epinephrine from Auvi-Q compared with EpiPen","volume":"111","author":"Edwards","year":"2013","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"4","key":"10.1016\/j.anai.2024.05.002_bib0022","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.jaip.2017.09.021","article-title":"Bioavailability and cardiovascular effects of adrenaline administered by Anapen autoinjector in healthy volunteers","volume":"6","author":"Duvauchelle","year":"2018","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13601-020-00326-x","article-title":"Epinephrine delivery via EpiPen\u00aeAuto-Injector or manual syringe across participants with a wide range of skin-to-muscle distances","volume":"10","author":"Worm","year":"2020","journal-title":"Clin Transl Allergy"},{"issue":"5","key":"10.1016\/j.anai.2024.05.002_bib0024","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S1081-1206(10)61130-1","article-title":"Adequacy of the epinephrine autoinjector needle length in delivering epinephrine to the intramuscular tissues","volume":"94","author":"Song","year":"2005","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"12","key":"10.1016\/j.anai.2024.05.002_bib0025","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1016\/j.ajem.2013.09.001","article-title":"Predictors of epinephrine autoinjector needle length inadequacy","volume":"31","author":"Bhalla","year":"2013","journal-title":"Am J Emerg Med"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0026","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1710-1492-10-39","article-title":"Auto-injector needle length may be inadequate to deliver epinephrine intramuscularly in women with confirmed food allergy","volume":"10","author":"Tsai","year":"2014","journal-title":"Allergy Asthma Clin Immunol"},{"issue":"6","key":"10.1016\/j.anai.2024.05.002_bib0027","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/all.12595","article-title":"Excess subcutaneous tissue may preclude intramuscular delivery when using adrenaline autoinjectors in patients with anaphylaxis","volume":"70","author":"Johnstone","year":"2015","journal-title":"Allergy Eur J Allergy Clin Immunol"},{"issue":"6","key":"10.1016\/j.anai.2024.05.002_bib0028","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.anai.2018.02.028","article-title":"Epinephrine auto-injector needle lengths: can both subcutaneous and periosteal\/intraosseous injection be avoided?","volume":"120","author":"Dreborg","year":"2018","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0029","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13223-020-00422-4","article-title":"Epinephrine auto-injector needle length","volume":"16","author":"Dreborg","year":"2020","journal-title":"Allergy Asthma Clin Immunol"},{"issue":"2","key":"10.1016\/j.anai.2024.05.002_bib0030","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1398-9995.2004.00620.x","article-title":"Accidental perforating bone injury using the EpiPen\u00ae autoinjection device","volume":"60","author":"Schintler","year":"2005","journal-title":"Allergy Eur J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0031","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13223-018-0257-6","article-title":"Unintentional injection to the bone with a pediatric epinephrine auto-injector","volume":"14","author":"Ibrahim","year":"2018","journal-title":"Allergy Asthma Clin Immunol"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0032","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1710-1492-10-40","article-title":"Children under 15 kg with food allergy may be at risk of having epinephrine auto-injectors administered into bone","volume":"10","author":"Kim","year":"2014","journal-title":"Allergy Asthma Clin Immunol"},{"issue":"6","key":"10.1016\/j.anai.2024.05.002_bib0033","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1185\/03007995.2010.481203","article-title":"Skin and subcutaneous adipose layer thickness in adults with diabetes at sites used for insulin injections: implications for needle length recommendations","volume":"26","author":"Gibney","year":"2010","journal-title":"Curr Med Res Opin"},{"issue":"2","key":"10.1016\/j.anai.2024.05.002_bib0034","doi-asserted-by":"crossref","first-page":"147","DOI":"10.2500\/aap.2021.42.200108","article-title":"Ideal body position for epinephrine autoinjector administration","volume":"42","author":"Wang","year":"2021","journal-title":"Allergy Asthma Proc"},{"issue":"2","key":"10.1016\/j.anai.2024.05.002_bib0035","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.jaip.2014.11.016","article-title":"The deep fascia of the thigh forms an impenetrable barrier to fluid injected subcutaneously by autoinjectors","volume":"3","author":"Diacono","year":"2015","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"2","key":"10.1016\/j.anai.2024.05.002_bib0036","doi-asserted-by":"crossref","first-page":"135","DOI":"10.4103\/0970-0358.73424","article-title":"Detail microscopic analysis of deep fascia of lower limb and its surgical implication","volume":"43","author":"Bhattacharya","year":"2010","journal-title":"Indian J Plast Surg Off Publ Assoc Plast Surg India"},{"key":"10.1016\/j.anai.2024.05.002_bib0037","series-title":"StatPearls","article-title":"Anatomy, fascia layers","author":"Gatt","year":"2024"},{"issue":"5","key":"10.1016\/j.anai.2024.05.002_bib0038","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1097\/PRS.0000000000009631","article-title":"In vivo analysis of the superficial and deep fascia","volume":"150","author":"Hammoudeh","year":"2022","journal-title":"Plast Reconstr Surg"},{"issue":"5","key":"10.1016\/j.anai.2024.05.002_bib0039","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.jaip.2015.05.024","article-title":"Epinephrine autoinjectors: compression and propulsion do have a role in delivery depth","volume":"3","author":"Song","year":"2015","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"2","key":"10.1016\/j.anai.2024.05.002_bib0040","first-page":"72","article-title":"Computed tomographic measurement of gluteal subcutaneous fat thickness in reference to failure of gluteal intramuscular injections","volume":"58","author":"Burbridge","year":"2007","journal-title":"Can Assoc Radiol J"},{"issue":"4","key":"10.1016\/j.anai.2024.05.002_bib0041","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.mjafi.2014.08.005","article-title":"Influence of skin-to-muscle and muscle-to-bone thickness on depth of needle penetration in adults at the deltoid intramuscular injection site","volume":"70","author":"Shankar","year":"2014","journal-title":"Med J Armed Forces India"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0042","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmjopen-2022-063530","article-title":"What variables should inform needle length choice for deltoid intramuscular injection? A systematic review","volume":"13","author":"Kearns","year":"2023","journal-title":"BMJ Open"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0043","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-022-05020-5","article-title":"Statistical estimation of deltoid subcutaneous fat pad thickness: implications for needle length for vaccination","volume":"12","author":"Sebro","year":"2022","journal-title":"Sci Rep"},{"issue":"19-20","key":"10.1016\/j.anai.2024.05.002_bib0044","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1111\/jocn.16126","article-title":"Dorsogluteal intramuscular injection depth needed to reach muscle tissue according to body mass index and gender: a systematic review","volume":"31","author":"Strohfus","year":"2022","journal-title":"J Clin Nurs"},{"key":"10.1016\/j.anai.2024.05.002_bib0045","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1109\/TBME.2015.2497245","article-title":"Toward standardized acoustic radiation force (ARF)-based ultrasound elasticity measurements with robotic force control","volume":"63","author":"Lediju Bell","year":"2016","journal-title":"IEEE Trans Bio Med Eng"},{"issue":"2","key":"10.1016\/j.anai.2024.05.002_bib0046","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3233\/WOR-172611","article-title":"A pilot study to precisely quantify forces applied by sonographers while scanning: a step toward reducing ergonomic injury","volume":"58","author":"Dhyani","year":"2017","journal-title":"Work"},{"issue":"1","key":"10.1016\/j.anai.2024.05.002_bib0047","first-page":"56","article-title":"Determination of suitable needle length for new epinephrine auto injectors","volume":"2","author":"Dreborg","year":"2020","journal-title":"J Allergy Res"},{"issue":"6","key":"10.1016\/j.anai.2024.05.002_bib0048","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.anai.2017.03.017","article-title":"Inadequacy of current pediatric epinephrine autoinjector needle length for use in infants and toddlers","volume":"118","author":"Kim","year":"2017","journal-title":"Ann Allergy Asthma Immunol"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120624002862?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120624002862?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T16:54:42Z","timestamp":1722617682000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1081120624002862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":48,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["S1081120624002862"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2024.05.002","relation":{},"ISSN":["1081-1206"],"issn-type":[{"type":"print","value":"1081-1206"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Frequencies and predictors of subcutaneous and intraosseous injection with 4 epinephrine autoinjector devices","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2024.05.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}