{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:27:40Z","timestamp":1793125660914,"version":"4.5.0"},"reference-count":214,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.anai.2025.05.016","type":"journal-article","created":{"date-parts":[[2025,5,18]],"date-time":"2025-05-18T10:22:27Z","timestamp":1747563747000},"page":"143-154","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Future of therapy and monitoring for eosinophilic esophagitis and eosinophilic gastrointestinal diseases"],"prefix":"10.1016","volume":"135","author":[{"given":"Andrew","family":"Dickerson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan S.","family":"Dellon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema S.","family":"Aceves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0001","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/BF01296781","article-title":"Esophageal eosinophilia with dysphagia. A distinct clinicopathologic syndrome","volume":"38","author":"Attwood","year":"1993","journal-title":"Dig Dis Sci"},{"issue":"33","key":"10.1016\/j.anai.2025.05.016_bib0002","first-page":"1419","volume":"124","author":"Straumann","year":"1994","journal-title":"Schweiz Med Wochenschr"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0003","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/0016-5085(95)90637-1","article-title":"Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula","volume":"109","author":"Kelly","year":"1995","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0004","doi-asserted-by":"crossref","first-page":"31","DOI":"10.14309\/ajg.0000000000003194","article-title":"ACG clinical guideline: diagnosis and management of eosinophilic esophagitis","volume":"120","author":"Dellon","year":"2025","journal-title":"Am J Gastroenterol"},{"issue":"7","key":"10.1016\/j.anai.2025.05.016_bib0005","article-title":"Medical treatment of eosinophilic esophagitis","volume":"7","author":"Franciosi","year":"2023","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0006","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.iac.2023.12.001","article-title":"Pathophysiology of eosinophilic esophagitis","volume":"44","author":"Kennedy","year":"2024","journal-title":"Immunol Allergy Clin North Am"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0007","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1172\/JCI124606","article-title":"Epithelial cell-derived cytokines: more than just signaling the alarm","volume":"129","author":"Roan","year":"2019","journal-title":"J Clin Invest"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0008","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1053\/j.gastro.2017.06.065","article-title":"Pathophysiology of eosinophilic esophagitis","volume":"154","author":"O\u2019Shea","year":"2018","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0009","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.gtc.2014.02.015","article-title":"Clinical implications and pathogenesis of esophageal remodeling in eosinophilic esophagitis","volume":"43","author":"Hirano","year":"2014","journal-title":"Gastroenterol Clin North Am"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0010","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.jaci.2010.12.1118","article-title":"Expression of mast cell-associated genes is upregulated in adult eosinophilic esophagitis and responds to steroid or dietary therapy","volume":"127","author":"Hsu Blatman","year":"2011","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0011","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.jaci.2006.10.016","article-title":"Esophageal remodeling in pediatric eosinophilic esophagitis","volume":"119","author":"Aceves","year":"2007","journal-title":"J Allergy Clin Immunol"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0012","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1053\/j.gastro.2007.08.017","article-title":"Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment","volume":"133","author":"Furuta","year":"2007","journal-title":"Gastroenterology"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0013","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1111\/j.1572-0241.2007.01396.x","article-title":"Variability in diagnostic criteria for eosinophilic esophagitis: a systematic review","volume":"102","author":"Dellon","year":"2007","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0014","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jaci.2011.02.040","article-title":"Eosinophilic esophagitis: updated consensus recommendations for children and adults","volume":"128","author":"Liacouras","year":"2011","journal-title":"J Allergy Clin Immunol"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0015","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1038\/ajg.2011.10","article-title":"Toward uniformity in the diagnosis of eosinophilic esophagitis (EoE): the effect of guidelines on variability of diagnostic criteria for EoE","volume":"106","author":"Sperry","year":"2011","journal-title":"Am J Gastroenterol"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0016","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1053\/j.gastro.2018.07.009","article-title":"Updated international consensus diagnostic criteria for eosinophilic esophagitis: Proceedings of the AGREE conference","volume":"155","author":"Dellon","year":"2018","journal-title":"Gastroenterology"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0017","doi-asserted-by":"crossref","first-page":"2928","DOI":"10.1007\/s10620-016-4204-4","article-title":"The 2010-2015 prevalence of eosinophilic esophagitis in the USA: A population-based study","volume":"61","author":"Mansoor","year":"2016","journal-title":"Dig Dis Sci"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0018","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.iac.2024.01.005","article-title":"Associations of eosinophilic gastrointestinal disorders with other gastrointestinal and allergic diseases","volume":"44","author":"Oliva","year":"2024","journal-title":"Immunol Allergy Clin North Am"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0019","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.jaip.2016.11.020","article-title":"The prevalence of eosinophilic esophagitis in pediatric patients with IgE-mediated food allergy","volume":"5","author":"Hill","year":"2017","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0020","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1016\/j.jaip.2018.05.010","article-title":"Eosinophilic esophagitis is a late manifestation of the allergic march","volume":"6","author":"Hill","year":"2018","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0021","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1053\/j.gastro.2017.06.067","article-title":"Epidemiology and natural history of eosinophilic esophagitis","volume":"154","author":"Dellon","year":"2018","journal-title":"Gastroenterology"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0022","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1111\/apt.15231","article-title":"Systematic review with meta-analysis: the growing incidence and prevalence of eosinophilic oesophagitis in children and adults in population-based studies","volume":"49","author":"Navarro","year":"2019","journal-title":"Aliment Pharmacol Ther"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0023","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.cgh.2024.09.031","article-title":"Prevalence and costs of eosinophilic esophagitis in the United States","volume":"23","author":"Thel","year":"2025","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"13","key":"10.1016\/j.anai.2025.05.016_bib0024","doi-asserted-by":"crossref","first-page":"3270","DOI":"10.1016\/j.cgh.2023.06.005","article-title":"Global incidence and prevalence of eosinophilic esophagitis, 1976-2022: A systematic review and meta-analysis","volume":"21","author":"Hahn","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"12","key":"10.1016\/j.anai.2025.05.016_bib0025","doi-asserted-by":"crossref","first-page":"3041","DOI":"10.1016\/j.cgh.2023.04.028","article-title":"Epidemiologic burden and projections for eosinophilic esophagitis-associated emergency department visits in the United States: 2009-2030","volume":"21","author":"Lam","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0026","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1053\/j.gastro.2019.09.042","article-title":"Efficacy of dupilumab in a Phase 2 randomized trial of adults with active eosinophilic esophagitis","volume":"158","author":"Hirano","year":"2020","journal-title":"Gastroenterology"},{"issue":"25","key":"10.1016\/j.anai.2025.05.016_bib0027","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1056\/NEJMoa2205982","article-title":"Dupilumab in adults and adolescents with eosinophilic esophagitis","volume":"387","author":"Dellon","year":"2022","journal-title":"N Engl J Med"},{"issue":"24","key":"10.1016\/j.anai.2025.05.016_bib0028","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1056\/NEJMoa2312282","article-title":"Dupilumab for eosinophilic esophagitis in patients 1 to 11 years of age","volume":"390","author":"Chehade","year":"2024","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0029","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.cgh.2021.04.022","article-title":"Budesonide Oral Suspension Improves Outcomes in Patients with Eosinophilic esophagitis: results from a phase 3 trial","volume":"20","author":"Hirano","year":"2022","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0030","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1016\/j.cgh.2024.04.020","article-title":"Crafting a therapeutic pyramid for eosinophilic esophagitis in the age of biologics","volume":"22","author":"Oliva","year":"2024","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0031","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1053\/j.gastro.2020.02.039","article-title":"Technical review on the management of eosinophilic esophagitis: a report from the AGA Institute and the Joint Task Force on allergy-immunology practice parameters","volume":"158","author":"Rank","year":"2020","journal-title":"Gastroenterology"},{"issue":"7","key":"10.1016\/j.anai.2025.05.016_bib0032","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1053\/j.gastro.2014.02.006","article-title":"Efficacy of dietary interventions for inducing histologic remission in patients with eosinophilic esophagitis: a systematic review and meta-analysis","volume":"146","author":"Arias","year":"2014","journal-title":"Gastroenterology"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0033","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1016\/j.cgh.2023.01.019","article-title":"Efficacy of elimination diets in eosinophilic esophagitis: A systematic review and meta-analysis","volume":"21","author":"Mayerhofer","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"12","key":"10.1016\/j.anai.2025.05.016_bib0034","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.14309\/ajg.0000000000001949","article-title":"Long-term outcomes of the six-food elimination diet and food reintroduction in a large cohort of adults with eosinophilic esophagitis","volume":"117","author":"Zalewski","year":"2022","journal-title":"Am J Gastroenterol"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0035","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/S2468-1253(23)00012-2","article-title":"One-food versus six-food elimination diet therapy for the treatment of eosinophilic oesophagitis: a multicentre, randomised, open-label trial","volume":"8","author":"Kliewer","year":"2023","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0036","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.jaci.2024.08.023","article-title":"One-food versus 4-food elimination diet for pediatric eosinophilic esophagitis: a multisite randomized trial","volume":"155","author":"Kliewer","year":"2025","journal-title":"J Allergy Clin Immunol"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0037","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1016\/j.jaci.2020.09.039","article-title":"Broad transcriptional response of the human esophageal epithelium to proton pump inhibitors","volume":"147","author":"Rochman","year":"2021","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0038","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1053\/j.gastro.2021.02.016","article-title":"In esophageal squamous cells from eosinophilic esophagitis patients, Th2 cytokines increase Eotaxin-3 secretion through effects on intracellular calcium and a non-gastric proton pump","volume":"160","author":"Odiase","year":"2021","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0039","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1136\/gutjnl-2012-302250","article-title":"Omeprazole blocks eotaxin-3 expression by oesophageal squamous cells from patients with eosinophilic oesophagitis and GORD","volume":"62","author":"Cheng","year":"2013","journal-title":"Gut"},{"issue":"11","key":"10.1016\/j.anai.2025.05.016_bib0040","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1016\/j.cgh.2014.02.037","article-title":"Proton pump inhibitors partially restore mucosal integrity in patients with proton pump inhibitor-responsive esophageal eosinophilia but not eosinophilic esophagitis","volume":"12","author":"van Rhijn","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0041","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.cgh.2015.07.041","article-title":"Efficacy of proton pump inhibitor drugs for inducing clinical and histologic remission in patients with symptomatic esophageal eosinophilia: a systematic review and meta-analysis","volume":"14","author":"Lucendo","year":"2016","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0042","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1053\/j.gastro.2006.08.033","article-title":"A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis","volume":"131","author":"Konikoff","year":"2006","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0043","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1053\/j.gastro.2010.05.001","article-title":"Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial","volume":"139","author":"Dohil","year":"2010","journal-title":"Gastroenterology"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0044","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1053\/j.gastro.2010.07.048","article-title":"Budesonide is effective in adolescent and adult patients with active eosinophilic esophagitis","volume":"139","author":"Straumann","year":"2010","journal-title":"Gastroenterology"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0045","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1136\/gutjnl-2014-308815","article-title":"A randomised, double-blind trial comparing budesonide formulations and dosages for short-term treatment of eosinophilic oesophagitis","volume":"65","author":"Miehlke","year":"2016","journal-title":"Gut"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0046","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1053\/j.gastro.2014.04.019","article-title":"Efficacy, dose reduction, and resistance to high-dose fluticasone in patients with eosinophilic esophagitis","volume":"147","author":"Butz","year":"2014","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0047","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.cgh.2014.05.021","article-title":"Efficacy and safety of oral budesonide suspension in pediatric patients with eosinophilic esophagitis","volume":"13","author":"Gupta","year":"2015","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0048","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1053\/j.gastro.2016.11.021","article-title":"Budesonide oral suspension improves symptomatic, endoscopic, and histologic parameters compared with placebo in patients with eosinophilic esophagitis","volume":"152","author":"Dellon","year":"2017","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0049","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2500\/ar.2017.8.0202","article-title":"Effect of topical beclomethasone on inflammatory markers in adults with eosinophilic esophagitis: a pilot study","volume":"8","author":"Bhardwaj","year":"2017","journal-title":"Allergy Rhinol (Providence)"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0050","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1053\/j.gastro.2019.03.025","article-title":"Efficacy of budesonide orodispersible tablets as induction therapy for eosinophilic esophagitis in a randomized placebo-controlled trial","volume":"157","author":"Lucendo","year":"2019","journal-title":"Gastroenterology"},{"issue":"8","key":"10.1016\/j.anai.2025.05.016_bib0051","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1111\/apt.15670","article-title":"Randomised clinical trial: the safety and tolerability of fluticasone propionate orally disintegrating tablets versus placebo for eosinophilic oesophagitis","volume":"51","author":"Hirano","year":"2020","journal-title":"Aliment Pharmacol Ther"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0052","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1080\/00365521.2021.1906314","article-title":"Topically applied mometasone furoate improves dysphagia in adult eosinophilic esophagitis - results from a double-blind, randomized, placebo-controlled trial","volume":"56","author":"Tytor","year":"2021","journal-title":"Scand J Gastroenterol"},{"issue":"11","key":"10.1016\/j.anai.2025.05.016_bib0053","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1016\/j.cgh.2022.02.013","article-title":"Fluticasone propionate orally disintegrating tablet (APT-1011) for eosinophilic esophagitis: randomized controlled trial","volume":"20","author":"Dellon","year":"2022","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0054","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1007\/s10620-017-4642-7","article-title":"Six-food elimination diet and topical steroids are effective for eosinophilic esophagitis: a meta-regression","volume":"62","author":"Cotton","year":"2017","journal-title":"Dig Dis Sci"},{"issue":"11","key":"10.1016\/j.anai.2025.05.016_bib0055","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S2468-1253(23)00204-2","article-title":"Efficacy and safety of dupilumab up to 52 weeks in adults and adolescents with eosinophilic oesophagitis (LIBERTY EoE TREET study): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial","volume":"8","author":"Rothenberg","year":"2023","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0056","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/apt.14123","article-title":"Systematic review with meta-analysis: endoscopic dilation is highly effective and safe in children and adults with eosinophilic oesophagitis","volume":"46","author":"Moawad","year":"2017","journal-title":"Aliment Pharmacol Ther"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0057","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.gie.2017.04.028","article-title":"Esophageal dilation with either bougie or balloon technique as a treatment for eosinophilic esophagitis: a systematic review and meta-analysis","volume":"86","author":"Dougherty","year":"2017","journal-title":"Gastrointest Endosc"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0058","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.anai.2022.12.014","article-title":"Clinical guidance for the use of dupilumab in eosinophilic esophagitis: a yardstick","volume":"130","author":"Aceves","year":"2023","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0059","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.jaci.2023.05.024","article-title":"Prospective study of an amino acid-based elemental diet in an eosinophilic gastritis and gastroenteritis nutrition trial","volume":"152","author":"Gonsalves","year":"2023","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0060","doi-asserted-by":"crossref","first-page":"984","DOI":"10.14309\/ajg.0000000000000228","article-title":"Increasing rates of diagnosis, substantial co-occurrence, and variable treatment patterns of eosinophilic gastritis, gastroenteritis, and colitis based on 10-year data across a multicenter consortium","volume":"114","author":"Pesek","year":"2019","journal-title":"Am J Gastroenterol"},{"issue":"8","key":"10.1016\/j.anai.2025.05.016_bib0061","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s11894-018-0645-6","article-title":"Diagnosis, natural history and treatment of eosinophilic enteritis: a review","volume":"20","author":"de Chambrun","year":"2018","journal-title":"Curr Gastroenterol Rep"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0062","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1016\/j.jaip.2019.01.053","article-title":"Modified oral enteric-coated budesonide regimens to treat pediatric eosinophilic gastroenteritis, a single center experience","volume":"7","author":"Kennedy","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0063","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.dld.2005.06.013","article-title":"Eosinophilic gastroenteritis with severe protein-losing enteropathy: successful treatment with budesonide","volume":"38","author":"Siewert","year":"2006","journal-title":"Dig Liver Dis"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0064","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/00042737-200104000-00021","article-title":"Eosinophilic gastroenteritis treated with non-enteric-coated budesonide tablets","volume":"13","author":"Tan","year":"2001","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.anai.2025.05.016_bib0065","unstructured":"Gonsalves N, Dellon ES, Kliewer KL, Yearout R, Arva NC, Besse JA. Dupilumab improves histologic and endoscopic aspects of eosinophilic gastritis: results from the multicenter, randomized, double-blind, placebo-controlled phase 2 DEGAS trial. Gastroenterology. In press."},{"issue":"7","key":"10.1016\/j.anai.2025.05.016_bib0066","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1016\/j.cgh.2023.03.006","article-title":"Development of a practical guide to implement and monitor diet therapy for eosinophilic esophagitis","volume":"21","author":"Chang","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0067","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1053\/j.gastro.2014.05.036","article-title":"Eosinophilic esophagitis in adults is associated with IgG4 and not mediated by IgE","volume":"147","author":"Clayton","year":"2014","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0068","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.jaci.2018.02.049","article-title":"Specific IgG4 antibodies to cow\u2019s milk proteins in pediatric patients with eosinophilic esophagitis","volume":"142","author":"Schuyler","year":"2018","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0069","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1111\/apt.15879","article-title":"Food-specific antibodies in oesophageal secretions: association with trigger foods in eosinophilic oesophagitis","volume":"52","author":"Peterson","year":"2020","journal-title":"Aliment Pharmacol Ther"},{"issue":"11","key":"10.1016\/j.anai.2025.05.016_bib0070","doi-asserted-by":"crossref","first-page":"3470","DOI":"10.1111\/all.14854","article-title":"Peripheral markers of allergen-specific immune activation predict clinical allergy in eosinophilic esophagitis","volume":"76","author":"Dilollo","year":"2021","journal-title":"Allergy"},{"issue":"12","key":"10.1016\/j.anai.2025.05.016_bib0071","doi-asserted-by":"crossref","DOI":"10.14309\/ctg.0000000000000099","article-title":"A novel allergen-specific immune signature-directed approach to dietary elimination in eosinophilic esophagitis","volume":"10","author":"Dellon","year":"2019","journal-title":"Clin Transl Gastroenterol"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0072","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1097\/MPG.0000000000002480","article-title":"CYP2C19 and STAT6 variants influence the outcome of proton pump inhibitor therapy in pediatric eosinophilic esophagitis","volume":"69","author":"Mougey","year":"2019","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0073","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1365-2036.2011.04922.x","article-title":"Results of ambulatory pH monitoring do not reliably predict response to therapy in patients with eosinophilic oesophagitis","volume":"35","author":"Francis","year":"2012","journal-title":"Aliment Pharmacol Ther"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0074","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1097\/MPG.0000000000002957","article-title":"Proton-pump inhibitor response prediction using esophageal microRNAs in children with eosinophilic esophagitis","volume":"71","author":"Ca\u00f1as","year":"2020","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0075","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1111\/apt.15957","article-title":"Efficacy of proton pump inhibitor therapy for eosinophilic oesophagitis in 630 patients: results from the EoE connect registry","volume":"52","author":"Laserna-Mendieta","year":"2020","journal-title":"Aliment Pharmacol Ther"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0076","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1007\/s10388-020-00783-0","article-title":"Vonoprazan shows efficacy similar to that of proton pump inhibitors with respect to symptomatic, endoscopic, and histological responses in patients with eosinophilic esophagitis","volume":"18","author":"Kuzumoto","year":"2021","journal-title":"Esophagus"},{"issue":"8","key":"10.1016\/j.anai.2025.05.016_bib0077","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1038\/ajg.2016.167","article-title":"Sustained acid suppression by potassium-competitive acid blocker (P-CAB) may be an attractive treatment candidate for patients with eosinophilic esophagitis","volume":"111","author":"Ishimura","year":"2016","journal-title":"Am J Gastroenterol"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0078","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.cgh.2014.07.034","article-title":"Predictors of response to steroid therapy for eosinophilic esophagitis and treatment of steroid-refractory patients","volume":"13","author":"Wolf","year":"2015","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.anai.2025.05.016_bib0079","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.14309\/00000434-201310001-00037","article-title":"Predictors of non-response to topical steroids treatment in eosinophilic esophagitis","volume":"108","author":"Moawad","year":"2013","journal-title":"Am J Gastroenterol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0080","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.gie.2015.11.019","article-title":"The extremely narrow-caliber esophagus is a treatment-resistant subphenotype of eosinophilic esophagitis","volume":"83","author":"Eluri","year":"2016","journal-title":"Gastrointest Endosc"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0081","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.gie.2020.01.015","article-title":"Clinical outcomes of adults with eosinophilic esophagitis with severe stricture","volume":"92","author":"Kim","year":"2020","journal-title":"Gastrointest Endosc"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0082","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1016\/j.cgh.2022.11.004","article-title":"Higher body mass index is associated with decreased treatment response to topical steroids in eosinophilic esophagitis","volume":"21","author":"Ketchem","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0083","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1398-9995.2009.02142.x","article-title":"Resolution of remodeling in eosinophilic esophagitis correlates with epithelial response to topical corticosteroids","volume":"65","author":"Aceves","year":"2010","journal-title":"Allergy"},{"issue":"12","key":"10.1016\/j.anai.2025.05.016_bib0084","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1111\/cea.13748","article-title":"Epigenetic methylation in Eosinophilic esophagitis: molecular ageing and novel biomarkers for treatment response","volume":"50","author":"Jensen","year":"2020","journal-title":"Clin Exp Allergy"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0085","doi-asserted-by":"crossref","DOI":"10.14309\/ctg.0000000000000622","article-title":"Validation of epigenetic markers for the prediction of response to topical corticosteroid treatment in eosinophilic esophagitis","volume":"14","author":"Jensen","year":"2023","journal-title":"Clin Transl Gastroenterol"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0086","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1111\/apt.18443","article-title":"clinical trial: safety and efficacy of a novel oesophageal delivery system for topical corticosteroids versus placebo in the treatment of eosinophilic oesophagitis","volume":"61","author":"Lucendo","year":"2025","journal-title":"Aliment Pharmacol Ther"},{"issue":"10S","key":"10.1016\/j.anai.2025.05.016_bib0087","doi-asserted-by":"crossref","first-page":"476","DOI":"10.14309\/01.ajg.0001032124.58501.0c","article-title":"Efficacy and pharmacokinetic results from ongoing dose escalation in RESOLVE, a phase 1b\/2a study of EP-104GI (extended-release fluticasone propionate intra-esophageal injection) for eosinophilic esophagitis","volume":"119","author":"Malone","year":"2024","journal-title":"Am J Gastroenterol"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0088","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1053\/j.gastro.2011.07.044","article-title":"An antibody against IL-5 reduces numbers of esophageal intraepithelial eosinophils in children with eosinophilic esophagitis","volume":"141","author":"Assa\u2019ad","year":"2011","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0089","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2011.11.044","article-title":"Reslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trial","volume":"129","author":"Spergel","year":"2012","journal-title":"J Allergy Clin Immunol"},{"issue":"24","key":"10.1016\/j.anai.2025.05.016_bib0090","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1056\/NEJMoa2313318","article-title":"Eosinophil depletion with Benralizumab for eosinophilic esophagitis","volume":"390","author":"Rothenberg","year":"2024","journal-title":"N Engl J Med"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0091","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1136\/gutjnl-2023-330337","article-title":"Mepolizumab for treatment of adolescents and adults with eosinophilic oesophagitis: a multicentre, randomised, double-blind, placebo-controlled clinical trial","volume":"72","author":"Dellon","year":"2023","journal-title":"Gut"},{"issue":"10S","key":"10.1016\/j.anai.2025.05.016_bib0092","doi-asserted-by":"crossref","first-page":"e316","DOI":"10.14309\/01.ajg.0000858424.48968.ad","article-title":"S446 Results from KRYPTOS, a phase 2\/3 study of lirentelimab (AK002) in adults and adolescents with EoE","volume":"117","author":"Dellon","year":"2022","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.anai.2025.05.016_bib0093","unstructured":"Dellon ES, Charriez CM, Zhang S, Falk GW, Oliva S, Ma C, et al. Cendakimab efficacy and safety in adult and adolescent patients with eosinophilic esophagitis: 48-week results from the randomized, placebo-controlled, phase 3 study. Am J Gastroenterol. In press."},{"key":"10.1016\/j.anai.2025.05.016_bib0094","first-page":"11","article-title":"Cendakimab is effective and safe in adult and adolescent patients with eosinophilic esophagitis: 24-week results from the randomized, placebo-controlled, phase 3 study","volume":"12","author":"Schoepfer","year":"2024","journal-title":"U Eur Gastroenterol J"},{"issue":"11","key":"10.1016\/j.anai.2025.05.016_bib0095","doi-asserted-by":"crossref","first-page":"3147","DOI":"10.1016\/j.jaip.2024.08.013","article-title":"Induction of sustained remission and reversal of pathologic transcriptome achieved with tezepelumab in an adolescent with eosinophilic esophagitis","volume":"12","author":"Sharlin","year":"2024","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0096","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01193-2022","article-title":"Inhaled anti-TSLP antibody fragment, ecleralimab, blocks responses to allergen in mild asthma","volume":"61","author":"Gauvreau","year":"2023","journal-title":"Eur Respir J"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0097","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/imr.13380","article-title":"Therapeutic monoclonal antibodies in allergy: targeting IgE, cytokine, and alarmin pathways","volume":"328","author":"Eggel","year":"2024","journal-title":"Immunol Rev"},{"key":"10.1016\/j.anai.2025.05.016_bib0098","unstructured":"Silverberg JI, Mustapa MN, Reid F, Lei A, Smith R, Moate R, et al. Efficacy and safety of tozorakimab in moderate-to-severe atopic dermatitis: a phase 2a randomized controlled trial (FRONTIER-2). J Eur Acad Dermatol Venereol. In press."},{"issue":"515","key":"10.1016\/j.anai.2025.05.016_bib0099","doi-asserted-by":"crossref","first-page":"eaax2945","DOI":"10.1126\/scitranslmed.aax2945","article-title":"Proof-of-concept clinical trial of etokimab shows a key role for IL-33 in atopic dermatitis pathogenesis","volume":"11","author":"Chen","year":"2019","journal-title":"Sci Transl Med"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0100","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.jaci.2021.03.044","article-title":"Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: a randomized clinical trial","volume":"148","author":"Kelsen","year":"2021","journal-title":"J Allergy Clin Immunol"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0101","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.cytogfr.2013.05.004","article-title":"The role of IL-15 in gastrointestinal diseases: a bridge between innate and adaptive immune response","volume":"24","author":"Pagliari","year":"2013","journal-title":"Cytokine Growth Factor Rev"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0102","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.3390\/ijms25031702","article-title":"The new therapeutic frontiers in the treatment of eosinophilic esophagitis: biological drugs","volume":"25","author":"Ridolo","year":"2024","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0103","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1053\/j.gastro.2010.03.057","article-title":"Interleukin-15 expression is increased in human eosinophilic esophagitis and mediates pathogenesis in mice","volume":"139","author":"Zhu","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.anai.2025.05.016_bib0104","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.cytogfr.2016.07.001","article-title":"Role of interleukin-18 in the pathophysiology of allergic diseases","volume":"32","author":"Sanders","year":"2016","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.anai.2025.05.016_bib0105","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/290687","article-title":"The relationship between interleukin-18 polymorphisms and allergic disease: a meta-analysis","volume":"2014","author":"Cheng","year":"2014","journal-title":"Biomed Res Int"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0106","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1038\/icb.2015.30","article-title":"Allergen-induced interleukin-18 promotes experimental eosinophilic oesophagitis in mice","volume":"93","author":"Dutt","year":"2015","journal-title":"Immunol Cell Biol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0107","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.jaci.2018.02.011","article-title":"A critical role for IL-18 in transformation and maturation of naive eosinophils to pathogenic eosinophils","volume":"142","author":"Venkateshaiah","year":"2018","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0108","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/bjd.19574","article-title":"Tralokinumab for moderate-to-severe atopic dermatitis: results from two 52-week, randomized, double-blind, multicentre, placebo-controlled phase III trials (ECZTRA 1 and ECZTRA 2)","volume":"184","author":"Wollenberg","year":"2021","journal-title":"Br J Dermatol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0109","doi-asserted-by":"crossref","DOI":"10.1080\/09546634.2024.2442720","volume":"36","author":"Blauvelt","year":"2025","journal-title":"J Dermatolog Treat"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0110","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jaci.2010.04.009","article-title":"Involvement of mast cells in eosinophilic esophagitis","volume":"126","author":"Abonia","year":"2010","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0111","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/j.jaci.2010.08.050","article-title":"Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF-\u03b21, and increase esophageal smooth muscle contraction","volume":"126","author":"Aceves","year":"2010","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0112","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/ajg.2010.412","article-title":"Tryptase staining of mast cells may differentiate eosinophilic esophagitis from gastroesophageal reflux disease","volume":"106","author":"Dellon","year":"2011","journal-title":"Am J Gastroenterol"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0113","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1111\/all.13530","article-title":"Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis","volume":"73","author":"Tappata","year":"2018","journal-title":"Allergy"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0114","doi-asserted-by":"crossref","first-page":"224","DOI":"10.14309\/ajg.0000000000000474","article-title":"Mast cell infiltration is associated with persistent symptoms and endoscopic abnormalities despite resolution of eosinophilia in pediatric eosinophilic esophagitis","volume":"115","author":"Bolton","year":"2020","journal-title":"Am J Gastroenterol"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0115","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1111\/j.1365-2559.2012.4303.x","article-title":"Atopic and non-atopic eosinophilic oesophagitis are distinguished by immunoglobulin E-bearing intraepithelial mast cells","volume":"61","author":"Mulder","year":"2012","journal-title":"Histopathology"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0116","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1016\/j.jaci.2022.04.012","article-title":"KIT as a master regulator of the mast cell lineage","volume":"149","author":"Tsai","year":"2022","journal-title":"J Allergy Clin Immunol"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0117","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1016\/j.jaip.2024.07.011","article-title":"Losartan treatment reduces esophageal eosinophilic inflammation in a subset of eosinophilic esophagitis","volume":"12","author":"Abonia","year":"2024","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0118","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1111\/j.1365-2222.2004.1931.x","article-title":"Effect of Mycobacterium tuberculosis chaperonins on bronchial eosinophilia and hyper-responsiveness in a murine model of allergic inflammation","volume":"34","author":"Riffo-Vasquez","year":"2004","journal-title":"Clin Exp Allergy"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0119","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1165\/rcmb.2011-0412OC","article-title":"Mycobacterium tuberculosis chaperonin 60.1 inhibits leukocyte diapedesis in a murine model of allergic lung inflammation","volume":"47","author":"Riffo-Vasquez","year":"2012","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.anai.2025.05.016_bib0120","doi-asserted-by":"crossref","first-page":"10S","DOI":"10.14309\/01.ajg.0000951480.82456.a1","article-title":"S460 Efficacy and safety of IRL201104, a novel peptide immunomodulator, in a phase 2a, double-blind, placebo-controlled multi-center study in patients with active eosinophilic esophagitis","volume":"118","author":"Dellon","year":"2023","journal-title":"Am J Gastroenterol"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0121","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s40265-021-01528-8","article-title":"Targeting sphingosine-1-phosphate signaling in immune-mediated diseases: beyond multiple sclerosis","volume":"81","author":"P\u00e9rez-Jeldres","year":"2021","journal-title":"Drugs"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0122","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.12836","article-title":"Sphingosine-1-phosphate receptors and innate immunity","volume":"20","author":"Bryan","year":"2018","journal-title":"Cell Microbiol"},{"issue":"10383","key":"10.1016\/j.anai.2025.05.016_bib0123","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S0140-6736(23)00061-2","article-title":"Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies","volume":"401","author":"Sandborn","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.anai.2025.05.016_bib0124","doi-asserted-by":"crossref","first-page":"10S","DOI":"10.14309\/01.ajg.0000951460.86738.5a","article-title":"Efficacy and safety of the selective sphingosine 1-phosphate receptor modulator, etrasimod, in Adult Patients with Eosinophilic Esophagitis over 52 weeks in the Phase 2 VOYAGE Study","volume":"118","author":"Dellon","year":"2023","journal-title":"Am J Gastroenterol"},{"issue":"8","key":"10.1016\/j.anai.2025.05.016_bib0125","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1038\/s41395-018-0145-1","article-title":"The anti-\u03b14\u03b27 integrin therapeutic antibody for inflammatory bowel disease, vedolizumab, ameliorates eosinophilic esophagitis: a novel clinical observation","volume":"113","author":"Nhu","year":"2018","journal-title":"Am J Gastroenterol"},{"issue":"11","key":"10.1016\/j.anai.2025.05.016_bib0126","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1016\/j.cgh.2018.06.022","article-title":"The potential role of vedolizumab in concomitant eosinophilic esophagitis and Crohn\u2019s disease","volume":"16","author":"Taft","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0127","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1007\/s10620-019-05704-5","article-title":"Resolution of refractory eosinophilic esophagitis with the leukocyte-trafficking inhibitor natalizumab","volume":"64","author":"Beales","year":"2019","journal-title":"Dig Dis Sci"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0128","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/all.12096","article-title":"Anti-eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis","volume":"68","author":"Straumann","year":"2013","journal-title":"Allergy"},{"issue":"12","key":"10.1016\/j.anai.2025.05.016_bib0129","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2019-232558","article-title":"Treatment-resistant eosinophilic oesophagitis successfully managed with tofacitinib","volume":"12","author":"Mendoza Alvarez","year":"2019","journal-title":"BMJ Case Rep"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0130","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s13555-024-01334-6","article-title":"Successful achievement of demanding outcomes in upadacitinib-treated atopic dermatitis patients: a real-world, 96-week single-centre study","volume":"15","author":"Gregoriou","year":"2025","journal-title":"Dermatol Ther (Heidelb)"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0131","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1111\/cea.12244","article-title":"Safety and efficacy of an oral CCR3 antagonist in patients with asthma and eosinophilic bronchitis: a randomized, placebo-controlled clinical trial","volume":"44","author":"Neighbour","year":"2014","journal-title":"Clin Exp Allergy"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0132","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.jaci.2018.05.003","article-title":"Novel peptide nanoparticle-biased antagonist of CCR3 blocks eosinophil recruitment and airway hyperresponsiveness","volume":"143","author":"Grozdanovic","year":"2019","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0133","first-page":"265","article-title":"Elements involved in promoting eosinophilic gastrointestinal disorders","volume":"6","author":"Shukla","year":"2015","journal-title":"J Genet Syndr Gene Ther"},{"key":"10.1016\/j.anai.2025.05.016_bib0134","doi-asserted-by":"crossref","first-page":"5593","DOI":"10.1038\/ncomms6593","article-title":"GWAS identifies four novel eosinophilic esophagitis loci","volume":"5","author":"Sleiman","year":"2014","journal-title":"Nat Commun"},{"key":"10.1016\/j.anai.2025.05.016_bib0135","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.815842","article-title":"Type 2 inflammation in eosinophilic esophagitis: from pathophysiology to therapeutic targets","volume":"12","author":"Racca","year":"2022","journal-title":"Front Physiol"},{"issue":"20","key":"10.1016\/j.anai.2025.05.016_bib0136","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.3390\/cells12202473","article-title":"Mechanistic insights into eosinophilic esophagitis: therapies targeting pathophysiological mechanisms","volume":"12","author":"Massironi","year":"2023","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0137","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jaci.2020.10.018","article-title":"Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes","volume":"147","author":"Kottyan","year":"2021","journal-title":"J Allergy Clin Immunol"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0138","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.86355","article-title":"Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment","volume":"1","author":"Davis","year":"2016","journal-title":"JCI Insight"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0139","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1111\/all.15069","article-title":"Butyrate and propionate restore interleukin 13-compromised esophageal epithelial barrier function","volume":"77","author":"Kleuskens","year":"2022","journal-title":"Allergy"},{"issue":"444","key":"10.1016\/j.anai.2025.05.016_bib0140","doi-asserted-by":"crossref","first-page":"eaap9736","DOI":"10.1126\/scitranslmed.aap9736","article-title":"The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses","volume":"10","author":"Azouz","year":"2018","journal-title":"Sci Transl Med"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0141","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/mi.2015.98","article-title":"LRRC31 is induced by IL-13 and regulates kallikrein expression and barrier function in the esophageal epithelium","volume":"9","author":"D\u2019Mello","year":"2016","journal-title":"Mucosal Immunol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0142","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jaci.2018.05.008","article-title":"Epithelial origin of eosinophilic esophagitis","volume":"142","author":"Rochman","year":"2018","journal-title":"J Allergy Clin Immunol"},{"issue":"545","key":"10.1016\/j.anai.2025.05.016_bib0143","doi-asserted-by":"crossref","first-page":"eaaz7773","DOI":"10.1126\/scitranslmed.aaz7773","article-title":"Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis","volume":"12","author":"Azouz","year":"2020","journal-title":"Sci Transl Med"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0144","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1097\/MEG.0b013e32825a6ab4","article-title":"Corticosteroid-dependent eosinophilic oesophagitis: azathioprine and 6-mercaptopurine can induce and maintain long-term remission","volume":"19","author":"Netzer","year":"2007","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0145","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.cgh.2019.05.014","article-title":"Efficacy of epicutaneous immunotherapy in children with milk-induced eosinophilic esophagitis","volume":"18","author":"Spergel","year":"2020","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0146","doi-asserted-by":"crossref","first-page":"25","DOI":"10.2174\/187221310789895649","article-title":"Topical use of sucralfate in epithelial wound healing: clinical evidences and molecular mechanisms of action","volume":"4","author":"Masuelli","year":"2010","journal-title":"Recent Pat Inflamm Allergy Drug Discov"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0147","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/cea.12201","article-title":"Invariant natural killer T cells in children with eosinophilic esophagitis","volume":"44","author":"Jyonouchi","year":"2014","journal-title":"Clin Exp Allergy"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0148","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1038\/cti.2013.13","article-title":"Invariant natural killer T-cell neutralization is a possible novel therapy for human eosinophilic esophagitis","volume":"3","author":"Rayapudi","year":"2014","journal-title":"Clin Transl Immunology"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0149","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1016\/j.jaci.2020.01.051","article-title":"Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multisite cohort","volume":"145","author":"Dunn","year":"2020","journal-title":"J Allergy Clin Immunol"},{"issue":"7","key":"10.1016\/j.anai.2025.05.016_bib0150","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S2468-1253(18)30096-7","article-title":"Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study","volume":"3","author":"Shoda","year":"2018","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0151","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.cgh.2018.09.005","article-title":"Clinical and molecular factors associated with histologic response to topical steroid treatment in patients with eosinophilic esophagitis","volume":"17","author":"Eluri","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0152","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.jaci.2020.10.003","article-title":"2020 Focused updates to the asthma management guidelines: a report from the national asthma education and prevention program coordinating committee expert panel working group","volume":"146","author":"Cloutier","year":"2020","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0153","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.jaci.2023.01.002","article-title":"Biologics in the treatment of asthma in children and adolescents","volume":"151","author":"Bacharier","year":"2023","journal-title":"J Allergy Clin Immunol"},{"issue":"24","key":"10.1016\/j.anai.2025.05.016_bib0154","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1056\/NEJMoa2406673","article-title":"Twice-yearly depemokimab in severe asthma with an eosinophilic phenotype","volume":"391","author":"Jackson","year":"2024","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0155","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.cgh.2023.08.039","article-title":"Withdrawal of immunomodulators or TNF antagonists in patients with inflammatory bowel diseases in remission on combination therapy: a systematic review and meta-analysis","volume":"22","author":"Katibian","year":"2024","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0156","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1097\/MPG.0000000000003877","article-title":"Joint ESPGHAN\/NASPGHAN guidelines on childhood eosinophilic gastrointestinal disorders beyond eosinophilic esophagitis","volume":"78","author":"Papadopoulou","year":"2024","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0157","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.gie.2022.05.013","article-title":"Endoscopic approach to eosinophilic esophagitis: American Society for Gastrointestinal Endoscopy Consensus Conference","volume":"96","author":"Aceves","year":"2022","journal-title":"Gastrointest Endosc"},{"issue":"12","key":"10.1016\/j.anai.2025.05.016_bib0158","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1016\/j.cgh.2021.07.011","article-title":"Optimizing the endoscopic examination in eosinophilic esophagitis","volume":"19","author":"Dellon","year":"2021","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0159","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1177\/2050640616689525","article-title":"Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults","volume":"5","author":"Lucendo","year":"2017","journal-title":"United European Gastroenterol J"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0160","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.1016\/j.cgh.2022.12.018","article-title":"Monitoring patients with eosinophilic esophagitis in routine clinical practice - International Expert Recommendations","volume":"21","author":"Arnim","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"7","key":"10.1016\/j.anai.2025.05.016_bib0161","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1055\/a-1675-7860","article-title":"Determination of a treatment response threshold for the eosinophilic esophagitis endoscopic reference score","volume":"54","author":"Cotton","year":"2022","journal-title":"Endoscopy"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0162","first-page":"1","article-title":"Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring","volume":"30","author":"Collins","year":"2017","journal-title":"Dis Esophagus"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0163","doi-asserted-by":"crossref","first-page":"220","DOI":"10.14740\/gr1423","article-title":"Usefulness of the eosinophilic esophagitis histologic scoring system in distinguishing active eosinophilic esophagitis from remission and gastroesophageal reflux disease","volume":"14","author":"Lin","year":"2021","journal-title":"Gastroenterology Res"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0164","doi-asserted-by":"crossref","first-page":"264","DOI":"10.14309\/ajg.0000000000001571","article-title":"Responsiveness of a histologic scoring system compared with peak eosinophil count in eosinophilic esophagitis","volume":"117","author":"Ma","year":"2022","journal-title":"Am J Gastroenterol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0165","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/apt.12413","article-title":"Development and field testing of a novel patient-reported outcome measure of dysphagia in patients with eosinophilic esophagitis","volume":"38","author":"Dellon","year":"2013","journal-title":"Aliment Pharmacol Ther"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0166","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1053\/j.gastro.2014.08.028","article-title":"Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis","volume":"147","author":"Schoepfer","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.anai.2025.05.016_bib0167","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/1471-230X-11-126","article-title":"Development of a validated patient-reported symptom metric for pediatric eosinophilic esophagitis: qualitative methods","volume":"11","author":"Franciosi","year":"2011","journal-title":"BMC Gastroenterol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0168","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/j.jaci.2015.03.004","article-title":"Pediatric Eosinophilic Esophagitis Symptom Scores (PEESS v2.0) identify histologic and molecular correlates of the key clinical features of disease","volume":"135","author":"Martin","year":"2015","journal-title":"J Allergy Clin Immunol"},{"issue":"11","key":"10.1016\/j.anai.2025.05.016_bib0169","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1016\/j.cgh.2019.01.030","article-title":"A conceptual approach to understanding treatment response in eosinophilic esophagitis","volume":"17","author":"Dellon","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0170","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1016\/j.cgh.2023.03.047","article-title":"A newly proposed severity index for eosinophilic esophagitis is associated with baseline clinical features and successful treatment response","volume":"21","author":"Cotton","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0171","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.cgh.2023.09.015","article-title":"The Index of Severity for Eosinophilic Esophagitis (I-SEE) reflects longitudinal clinicopathologic changes in children","volume":"22","author":"Dickerson","year":"2024","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0172","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1053\/j.gastro.2022.03.025","article-title":"A clinical severity index for eosinophilic esophagitis: development, consensus, and future directions","volume":"163","author":"Dellon","year":"2022","journal-title":"Gastroenterology"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0173","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/S2468-1253(23)00145-0","article-title":"Benralizumab for eosinophilic gastritis: a single-site, randomised, double-blind, placebo-controlled, phase 2 trial","volume":"8","author":"Kliewer","year":"2023","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0174","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1097\/MPG.0000000000001336","article-title":"Dilation of pediatric eosinophilic esophagitis: adverse events and short-term outcomes","volume":"64","author":"Menard-Katcher","year":"2017","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0175","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgast-2021-000688","article-title":"Complications of diagnostic upper gastrointestinal endoscopy: common and rare - recognition, assessment and management","volume":"9","author":"Waddingham","year":"2022","journal-title":"BMJ Open Gastroenterol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0176","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.gie.2011.06.040","article-title":"Adequacy of esophageal squamous mucosa specimens obtained during endoscopy: are standard biopsies sufficient for postablation surveillance in Barrett\u2019s esophagus?","volume":"75","author":"Gupta","year":"2012","journal-title":"Gastrointest Endosc"},{"issue":"11","key":"10.1016\/j.anai.2025.05.016_bib0177","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1016\/j.cgh.2023.03.014","article-title":"Esophageal epithelium and lamina propria are unevenly involved in eosinophilic esophagitis","volume":"21","author":"Hiremath","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0178","doi-asserted-by":"crossref","first-page":"272","DOI":"10.14309\/ajg.0000000000001587","article-title":"Development and validation of web-based tool to predict lamina propria fibrosis in eosinophilic esophagitis","volume":"117","author":"Hiremath","year":"2022","journal-title":"Am J Gastroenterol"},{"issue":"12","key":"10.1016\/j.anai.2025.05.016_bib0179","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1055\/s-0042-117274","article-title":"Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis","volume":"48","author":"Bussmann","year":"2016","journal-title":"Endoscopy"},{"issue":"11-12","key":"10.1016\/j.anai.2025.05.016_bib0180","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1111\/apt.12977","article-title":"Oesophageal narrowing is common and frequently under-appreciated at endoscopy in patients with oesophageal eosinophilia","volume":"40","author":"Gentile","year":"2014","journal-title":"Aliment Pharmacol Ther"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0181","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1097\/MPG.0000000000000849","article-title":"Contribution of esophagram to the evaluation of complicated pediatric eosinophilic esophagitis","volume":"61","author":"Menard-Katcher","year":"2015","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"12","key":"10.1016\/j.anai.2025.05.016_bib0182","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1111\/nmo.12888","article-title":"Evaluation of esophageal distensibility in eosinophilic esophagitis: an update and comparison of functional lumen imaging probe analytic methods","volume":"28","author":"Carlson","year":"2016","journal-title":"Neurogastroenterol Motil"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0183","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1053\/j.gastro.2010.09.037","article-title":"Mechanical properties of the esophagus in eosinophilic esophagitis","volume":"140","author":"Kwiatek","year":"2011","journal-title":"Gastroenterology"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0184","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1055\/s-0042-107340","article-title":"Severity of endoscopically identified esophageal rings correlates with reduced esophageal distensibility in eosinophilic esophagitis","volume":"48","author":"Chen","year":"2016","journal-title":"Endoscopy"},{"issue":"5","key":"10.1016\/j.anai.2025.05.016_bib0185","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1016\/j.cgh.2022.08.044","article-title":"Esophageal distensibility defines fibrostenotic severity in pediatric eosinophilic esophagitis","volume":"21","author":"Hoffmann","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0186","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.gie.2015.05.044","article-title":"Unsedated transnasal esophagoscopy for monitoring therapy in pediatric eosinophilic esophagitis","volume":"83","author":"Friedlander","year":"2016","journal-title":"Gastrointest Endosc"},{"issue":"12","key":"10.1016\/j.anai.2025.05.016_bib0187","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1016\/j.cgh.2019.01.023","article-title":"Transnasal endoscopy in unsedated children with eosinophilic esophagitis using virtual reality video goggles","volume":"17","author":"Nguyen","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0188","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1097\/MPG.0000000000003029","article-title":"Pediatric patients\u2019 and parents\u2019 perspectives of unsedated transnasal endoscopy in eosinophilic esophagitis: a qualitative descriptive study","volume":"72","author":"Scherer","year":"2021","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0189","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1111\/jgh.13173","article-title":"Ultrathin unsedated transnasal gastroscopy in monitoring eosinophilic esophagitis","volume":"31","author":"Philpott","year":"2016","journal-title":"J Gastroenterol Hepatol"},{"issue":"9","key":"10.1016\/j.anai.2025.05.016_bib0190","doi-asserted-by":"crossref","first-page":"3494","DOI":"10.1016\/j.jaip.2021.06.030","article-title":"Unsedated transnasal esophagoscopy with virtual reality distraction enables earlier monitoring of dietary therapy in eosinophilic esophagitis","volume":"9","author":"Friedlander","year":"2021","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0191","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.giec.2022.10.006","article-title":"Pediatric unsedated transnasal endoscopy","volume":"33","author":"Venkatesh","year":"2023","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"10.1016\/j.anai.2025.05.016_bib0192","doi-asserted-by":"crossref","unstructured":"Dollin Y.T., Mark J.A., Andrews R., Pan Z., Ort C., Kramer R.E., et al. Adverse events are lower in unsedated transnasal esophagoscopy versus sedated esophagogastroduodenoscopy [e-pub ahead of print]. J Pediatr Gastroenterol Nutr. doi:10.1002\/jpn3.70061, accessed May 2, 2025.","DOI":"10.1002\/jpn3.70061"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0193","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1038\/ajg.2017.244","article-title":"Accuracy and safety of the cytosponge for assessing histologic activity in eosinophilic esophagitis: a two-center study","volume":"112","author":"Katzka","year":"2017","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0194","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.cgh.2014.06.026","article-title":"Accuracy, safety, and tolerability of tissue collection by Cytosponge vs endoscopy for evaluation of eosinophilic esophagitis","volume":"13","author":"Katzka","year":"2015","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0195","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.cgh.2018.07.043","article-title":"Safety and acceptability of esophageal cytosponge cell collection device in a pooled analysis of data from individual patients","volume":"17","author":"Januszewicz","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0196","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1136\/gutjnl-2012-303171","article-title":"The oesophageal string test: a novel, minimally invasive method measures mucosal inflammation in eosinophilic oesophagitis","volume":"62","author":"Furuta","year":"2013","journal-title":"Gut"},{"issue":"10","key":"10.1016\/j.anai.2025.05.016_bib0197","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.14309\/ajg.0000000000000371","article-title":"One-hour esophageal string test: A nonendoscopic minimally invasive test that accurately detects disease activity in eosinophilic esophagitis","volume":"114","author":"Ackerman","year":"2019","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0198","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1007\/s10620-024-08777-z","article-title":"Development and validation of the PICK-UP-STRICS score to predict fibrostenosis in patients with EoE prior to endoscopy","volume":"70","author":"Chang","year":"2025","journal-title":"Dig Dis Sci"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0199","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.anai.2018.05.005","article-title":"Minimally invasive biomarker studies in eosinophilic esophagitis: a systematic review","volume":"121","author":"Hines","year":"2018","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"17","key":"10.1016\/j.anai.2025.05.016_bib0200","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.3390\/diagnostics13172806","article-title":"Non-invasive and minimally invasive biomarkers for the management of eosinophilic esophagitis beyond peak eosinophil counts: filling the gap in clinical practice","volume":"13","author":"Visaggi","year":"2023","journal-title":"Diagnostics (Basel)"},{"issue":"4","key":"10.1016\/j.anai.2025.05.016_bib0201","doi-asserted-by":"crossref","first-page":"3669","DOI":"10.3390\/ijms24043669","article-title":"Blood-based biomarkers for eosinophilic esophagitis and concomitant atopic diseases: a look into the potential of extracellular vesicles","volume":"24","author":"Grueso-Navarro","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0202","doi-asserted-by":"crossref","first-page":"dox139","DOI":"10.1093\/dote\/dox139","article-title":"Normalized serum eosinophil peroxidase levels are inversely correlated with esophageal eosinophilia in eosinophilic esophagitis","volume":"31","author":"Wright","year":"2018","journal-title":"Dis Esophagus"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0203","doi-asserted-by":"crossref","first-page":"145","DOI":"10.2500\/aap.2023.44.220102","article-title":"Salivary microRNAs in pediatric eosinophilic esophagitis","volume":"44","author":"Jhaveri","year":"2023","journal-title":"Allergy Asthma Proc"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0204","doi-asserted-by":"crossref","first-page":"639","DOI":"10.3390\/ijms26020639","article-title":"MicroRNAs in plasma-derived extracellular vesicles as non-invasive biomarkers for eosinophilic esophagitis","volume":"26","author":"Grueso-Navarro","year":"2025","journal-title":"Int J Mol Sci"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0205","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1111\/cea.13070","article-title":"Serum autoantibodies against epithelial cell adhesion molecules as disease biomarkers of eosinophilic esophagitis","volume":"48","author":"Dellon","year":"2018","journal-title":"Clin Exp Allergy"},{"issue":"1","key":"10.1016\/j.anai.2025.05.016_bib0206","first-page":"1","article-title":"CSTB and FABP5 serum mRNA differentiate histologically active and inactive patients with eosinophilic esophagitis","volume":"3","author":"Sninsky","year":"2023","journal-title":"Gastro Hepatol Adv"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0207","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/j.cgh.2023.10.028","article-title":"Peripheral blood IL5RA gene expression as a diagnostic biomarker for eosinophilic esophagitis","volume":"22","author":"Sninsky","year":"2024","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"12","key":"10.1016\/j.anai.2025.05.016_bib0208","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1016\/j.cgh.2014.06.019","article-title":"Markers of eosinophilic inflammation for diagnosis of eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia: a prospective study","volume":"12","author":"Dellon","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"3","key":"10.1016\/j.anai.2025.05.016_bib0209","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.jaci.2022.03.022","article-title":"Esophageal remodeling in eosinophilic esophagitis: relationships to luminal captured biomarkers of inflammation and periostin","volume":"150","author":"Muir","year":"2022","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0210","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1177\/10935266211041086","article-title":"Acquired esophageal strictures in children: morphometric and immunohistochemical analyses","volume":"25","author":"Collins","year":"2022","journal-title":"Pediatr Dev Pathol"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0211","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1053\/j.gastro.2013.08.046","article-title":"Molecular diagnosis of eosinophilic esophagitis by gene expression profiling","volume":"145","author":"Wen","year":"2013","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.anai.2025.05.016_bib0212","doi-asserted-by":"crossref","first-page":"e74","DOI":"10.1038\/ctg.2017.2","article-title":"A gene expression panel is accurate for diagnosis and monitoring treatment of eosinophilic esophagitis in adults","volume":"8","author":"Dellon","year":"2017","journal-title":"Clin Transl Gastroenterol"},{"issue":"7","key":"10.1016\/j.anai.2025.05.016_bib0213","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1136\/gutjnl-2023-331743","article-title":"Novel transcriptomic panel identifies histologically active eosinophilic oesophagitis","volume":"73","author":"Gueguen","year":"2024","journal-title":"Gut"},{"issue":"6","key":"10.1016\/j.anai.2025.05.016_bib0214","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1016\/j.jaip.2021.03.027","article-title":"Do rural health disparities affect prevalence data in pediatric eosinophilic esophagitis?","volume":"9","author":"Sabet","year":"2021","journal-title":"J Allergy Clin Immunol Pract"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108112062500242X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108112062500242X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:33:56Z","timestamp":1753868036000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S108112062500242X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":214,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S108112062500242X"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2025.05.016","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Future of therapy and monitoring for eosinophilic esophagitis and eosinophilic gastrointestinal diseases","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2025.05.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}