{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T21:25:39Z","timestamp":1794000339428,"version":"4.8.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB\/TRR 156"],"award-info":[{"award-number":["SFB\/TRR 156"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SCHA 1693_2-1"],"award-info":[{"award-number":["SCHA 1693_2-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma &amp; Immunology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.anai.2025.06.019","type":"journal-article","created":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T11:08:15Z","timestamp":1750504095000},"page":"443-447.e3","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of the PEN-FAST clinical decision rule in non\u2013beta-lactam antibiotic allergy assessment"],"prefix":"10.1016","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-8019-7144","authenticated-orcid":false,"given":"Deniz","family":"G\u00f6cebe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elham","family":"Khatamzas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Enk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knut","family":"Sch\u00e4kel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.anai.2025.06.019_bib0001","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaip.2023.06.025","article-title":"The burden of self-reported antibiotic allergies in health care and how to address it: a systematic review of the evidence","volume":"11","author":"Arnold","year":"2023","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"5","key":"10.1016\/j.anai.2025.06.019_bib0002","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1017\/ice.2020.1229","article-title":"The impact of antibiotic allergy labels on antibiotic exposure, clinical outcomes, and healthcare costs: a systematic review","volume":"42","author":"Krah","year":"2021","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"10167","key":"10.1016\/j.anai.2025.06.019_bib0003","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0140-6736(18)32218-9","article-title":"Antibiotic allergy","volume":"393","author":"Blumenthal","year":"2019","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.anai.2025.06.019_bib0004","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/s44259-024-00035-6","article-title":"Narrative review of recent developments and the future of penicillin allergy de-labelling by non-allergists","volume":"2","author":"Powell","year":"2024","journal-title":"NPJ Antimicrob Resist"},{"issue":"9","key":"10.1016\/j.anai.2025.06.019_bib0005","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.33703","article-title":"Validation of the PEN-FAST score in a pediatric population","volume":"5","author":"Copaescu","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"11","key":"10.1016\/j.anai.2025.06.019_bib0006","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.1016\/j.jaip.2024.07.012","article-title":"Comparative performance of 4 penicillin-allergy prediction strategies in a large cohort","volume":"12","author":"Ghiordanescu","year":"2024","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.anai.2025.06.019_bib0007","doi-asserted-by":"crossref","DOI":"10.3389\/falgy.2024.1439698","article-title":"Efficacy of the PEN-FAST score in a French cohort of patients with reported allergy to penicillins","volume":"5","author":"Hanniet","year":"2024","journal-title":"Front Allergy"},{"issue":"1","key":"10.1016\/j.anai.2025.06.019_bib0008","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.anai.2021.07.005","article-title":"Predictive factors of amoxicillin immediate hypersensitivity and validation of PEN-FAST clinical decision rule","volume":"128","author":"Piotin","year":"2022","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"8","key":"10.1016\/j.anai.2025.06.019_bib0009","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1001\/jamainternmed.2023.1572","article-title":"Evaluating the PEN-FAST clinical decision-making tool to enhance penicillin allergy delabeling","volume":"183","author":"Su","year":"2023","journal-title":"JAMA Intern Med"},{"issue":"5","key":"10.1016\/j.anai.2025.06.019_bib0010","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1001\/jamainternmed.2020.0403","article-title":"Development and validation of a penicillin allergy clinical decision rule","volume":"180","author":"Trubiano","year":"2020","journal-title":"JAMA Intern Med"},{"issue":"3","key":"10.1016\/j.anai.2025.06.019_bib0011","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s12016-021-08919-5","article-title":"Road less traveled: drug hypersensitivity to fluoroquinolones, vancomycin, tetracyclines, and macrolides","volume":"62","author":"Zhu","year":"2022","journal-title":"Clin Rev Allergy Immunol"},{"issue":"2","key":"10.1016\/j.anai.2025.06.019_bib0012","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.anai.2022.10.006","article-title":"Skin testing as a biomarker in drug allergy","volume":"130","author":"Saff","year":"2023","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.06.019_bib0013","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.16776","article-title":"Development and validation of a sulfa antibiotic allergy clinical decision rule","volume":"6","author":"Waldron","year":"2023","journal-title":"JAMA Netw Open"},{"issue":"3","key":"10.1016\/j.anai.2025.06.019_bib0014","first-page":"112","article-title":"Antimicrobial desensitization: a review of published protocols","volume":"7","author":"Chastain","year":"2019","journal-title":"Pharmacol (Basel)"},{"issue":"6","key":"10.1016\/j.anai.2025.06.019_bib0015","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1016\/j.jaci.2022.08.028","article-title":"Drug allergy: a 2022 practice parameter update","volume":"150","author":"Khan","year":"2022","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"10.1016\/j.anai.2025.06.019_bib0016","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.jaip.2014.12.012","article-title":"Moxifloxacin hypersensitivity: uselessness of skin testing","volume":"3","author":"Uyttebroek","year":"2015","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.anai.2025.06.019_bib0017","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5414\/ALX02311E","article-title":"Hypersensitivity to non-\u03b2-lactam antibiotics","volume":"6","author":"Merk","year":"2022","journal-title":"Allergol Select"},{"issue":"9","key":"10.1016\/j.anai.2025.06.019_bib0018","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1001\/jamainternmed.2023.2986","article-title":"Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk penicillin allergy: the PALACE randomized clinical trial","volume":"183","author":"Copaescu","year":"2023","journal-title":"JAMA Intern Med"},{"issue":"suppl 3","key":"10.1016\/j.anai.2025.06.019_bib0019","first-page":"S1","article-title":"Allergy diagnostic testing: an updated practice parameter","volume":"100","author":"Bernstein","year":"2008","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.06.019_bib0020","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1111\/all.14122","article-title":"Towards a more precise diagnosis of hypersensitivity to beta-lactams - an EAACI position paper","volume":"75","author":"Romano","year":"2020","journal-title":"Allergy"},{"issue":"3","key":"10.1016\/j.anai.2025.06.019_bib0021","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1159\/000199720","article-title":"Allergy diagnostic testing in clindamycin-induced skin reactions","volume":"149","author":"Seitz","year":"2009","journal-title":"Int Arch Allergy Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.06.019_bib0022","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.0105-1873.2005.00716.x","article-title":"Clindamycin skin testing has limited diagnostic potential","volume":"53","author":"Notman","year":"2005","journal-title":"Contact Dermatitis"},{"issue":"4","key":"10.1016\/j.anai.2025.06.019_bib0023","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1046\/j.1365-2133.2002.04665.x","article-title":"Cutaneous adverse reactions to clindamycin: results of skin tests and oral exposure","volume":"146","author":"Lammintausta","year":"2002","journal-title":"Br J Dermatol"},{"issue":"6","key":"10.1016\/j.anai.2025.06.019_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinf.2025.106495","article-title":"Development and validation of a cephalosporin allergy clinical decision rule","volume":"90","author":"Cox","year":"2025","journal-title":"J Infect"}],"container-title":["Annals of Allergy, Asthma &amp; Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120625003114?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120625003114?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T22:32:02Z","timestamp":1778797922000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1081120625003114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S1081120625003114"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2025.06.019","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of the PEN-FAST clinical decision rule in non\u2013beta-lactam antibiotic allergy assessment","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2025.06.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}