{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T12:48:28Z","timestamp":1777639708124,"version":"3.51.4"},"reference-count":66,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.anai.2025.10.003","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T04:48:33Z","timestamp":1760071713000},"page":"25-32","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Hard to digest"],"prefix":"10.1016","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1684-0912","authenticated-orcid":false,"given":"Rachel N.","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jai P.","family":"Ahluwalia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aiden C.","family":"Bingemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anitha","family":"Shrikhande","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theresa A.","family":"Bingemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0001","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/j.jaci.2019.06.032","article-title":"Food protein-induced enterocolitis syndrome in the US population-based study","volume":"144","author":"Nowak-Wegrzyn","year":"2019","journal-title":"J Allergy Clin Immunol"},{"issue":"9","key":"10.1016\/j.anai.2025.10.003_bib0002","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1016\/j.jaip.2022.05.006","article-title":"Food protein-induced enterocolitis syndrome in adulthood: clinical characteristics, prognosis, and risk factors","volume":"10","author":"Gonz\u00e1lez-Delgado","year":"2022","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0003","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/j.jaci.2016.12.966","article-title":"International consensus guidelines for the diagnosis and management of food protein-induced enterocolitis syndrome: executive summary-Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology","volume":"139","author":"Nowak-W\u0119grzyn","year":"2017","journal-title":"J Allergy Clin Immunol"},{"issue":"10","key":"10.1016\/j.anai.2025.10.003_bib0004","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.1111\/all.16142","article-title":"Medical algorithm: diagnosis and management of adult food protein-induced enterocolitis syndrome","volume":"79","author":"Gonzalez-Delgado","year":"2024","journal-title":"Allergy"},{"issue":"2","key":"10.1016\/j.anai.2025.10.003_bib0005","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.anai.2024.11.014","article-title":"Are we a step closer to giving patients with food protein-induced enterocolitis syndrome and caregivers what they want?","volume":"134","author":"Bingemann","year":"2025","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"11","key":"10.1016\/j.anai.2025.10.003_bib0006","doi-asserted-by":"crossref","first-page":"2986","DOI":"10.1016\/j.jaip.2022.06.013","article-title":"The natural course of adult-onset food protein-induced enterocolitis syndrome","volume":"10","author":"Crespo","year":"2022","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.anai.2025.10.003_bib0007","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ejphar.2013.09.075","article-title":"Neurochemical mechanisms and pharmacologic strategies in managing nausea and vomiting related to cyclic vomiting syndrome and other gastrointestinal disorders","volume":"722","author":"Bashashati","year":"2014","journal-title":"Eur J Pharmacol"},{"issue":"14","key":"10.1016\/j.anai.2025.10.003_bib0008","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1113\/jphysiol.2014.270892","article-title":"Physiological underpinnings of irritable bowel syndrome: neurohormonal mechanisms","volume":"592","author":"Camilleri","year":"2014","journal-title":"J Physiol"},{"issue":"9","key":"10.1016\/j.anai.2025.10.003_bib0009","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1001\/jama.2020.22532","article-title":"Diagnosis and treatment of irritable bowel syndrome: a review","volume":"325","author":"Camilleri","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.anai.2025.10.003_bib0010","first-page":"71","article-title":"The epidemiology of irritable bowel syndrome","volume":"6","author":"Canavan","year":"2014","journal-title":"Clin Epidemiol"},{"issue":"3","key":"10.1016\/j.anai.2025.10.003_bib0011","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/MCG.0b013e31802cbc2f","article-title":"Fructose intolerance in IBS and utility of fructose-restricted diet","volume":"42","author":"Choi","year":"2008","journal-title":"J Clin Gastroenterol"},{"issue":"1","key":"10.1016\/j.anai.2025.10.003_bib0012","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/s11894-013-0370-0","article-title":"Dietary fructose intolerance, fructan intolerance and FODMAPs","volume":"16","author":"Fedewa","year":"2014","journal-title":"Curr Gastroenterol Rep"},{"issue":"3","key":"10.1016\/j.anai.2025.10.003_bib0013","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.pop.2013.05.006","article-title":"Acute gastroenteritis","volume":"40","author":"Graves","year":"2013","journal-title":"Prim Care"},{"issue":"suppl 2","key":"10.1016\/j.anai.2025.10.003_bib0014","article-title":"Cyclic vomiting syndrome: pathophysiology, comorbidities, and future research directions","volume":"31","author":"Hasler","year":"2019","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.anai.2025.10.003_bib0015","doi-asserted-by":"crossref","DOI":"10.5402\/2012\/463689","article-title":"Eosinophilic gastrointestinal diseases: review and update","volume":"2012","author":"Jawairia","year":"2012","journal-title":"ISRN Gastroenterol"},{"issue":"3","key":"10.1016\/j.anai.2025.10.003_bib0016","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1097\/MPG.0b013e318173ed39","article-title":"North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition consensus statement on the diagnosis and management of cyclic vomiting syndrome","volume":"47","author":"Li","year":"2008","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"11","key":"10.1016\/j.anai.2025.10.003_bib0017","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.3390\/ph17111549","article-title":"A comprehensive review and update on cannabis hyperemesis syndrome","volume":"17","author":"Loganathan","year":"2024","journal-title":"Pharmaceuticals (Basel)"},{"key":"10.1016\/j.anai.2025.10.003_bib0018","doi-asserted-by":"crossref","DOI":"10.1177\/17562848221114558","article-title":"Extraintestinal manifestations in irritable bowel syndrome: a systematic review","volume":"15","author":"Ohlsson","year":"2022","journal-title":"Therap Adv Gastroenterol"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0019","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.anai.2022.10.021","article-title":"An allergist\u2019s approach to food poisoning","volume":"130","author":"Patel","year":"2023","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"5","key":"10.1016\/j.anai.2025.10.003_bib0020","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/ajg.2013.96","article-title":"Short-chain carbohydrates and functional gastrointestinal disorders","volume":"108","author":"Shepherd","year":"2013","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"10.1016\/j.anai.2025.10.003_bib0021","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jaci.2010.01.055","article-title":"Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract","volume":"126","author":"Simon","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2025.10.003_bib0022","unstructured":"Stuempfig ND, Tobin EH, Seroy J. Viral Gastroenteritis; 2025. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK518995\/. Accessed September 8, 2025."},{"issue":"2","key":"10.1016\/j.anai.2025.10.003_bib0023","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.jadohealth.2020.07.035","article-title":"Diagnosis and acute management of adolescent cannabinoid hyperemesis syndrome: a systematic review","volume":"68","author":"Zhu","year":"2021","journal-title":"J Adolesc Health"},{"issue":"3","key":"10.1016\/j.anai.2025.10.003_bib0024","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.anai.2022.09.029","article-title":"Are we missing food-protein-induced enterocolitis syndrome in adults?","volume":"130","author":"Bingemann","year":"2023","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"2","key":"10.1016\/j.anai.2025.10.003_bib0025","doi-asserted-by":"crossref","first-page":"136","DOI":"10.18176\/jiaci.0835","article-title":"Food protein-induced enterocolitis syndrome in an adult population from Spain","volume":"33","author":"Garc\u00eda Paz","year":"2023","journal-title":"J Investig Allergol Clin Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.10.003_bib0026","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.anai.2020.08.009","article-title":"Chronic adult food protein-induced enterocolitis syndrome","volume":"125","author":"Gonzalez-Delgado","year":"2020","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0027","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/j.jaip.2020.11.047","article-title":"Relevant features of adult-onset food protein-induced enterocolitis syndrome","volume":"9","author":"Crespo","year":"2021","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"2","key":"10.1016\/j.anai.2025.10.003_bib0028","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.anai.2024.09.019","article-title":"Formulation of adult food-protein-induced enterocolitis syndrome diagnostic scoring system differentiating from immediate-type food allergy","volume":"134","author":"Watanabe","year":"2025","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0029","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.jaip.2022.12.017","article-title":"Challenges and unmet needs in FPIES from the parents and adult patients\u2019 perspective: an international survey","volume":"11","author":"Vazquez-Ortiz","year":"2023","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"2","key":"10.1016\/j.anai.2025.10.003_bib0030","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.anai.2024.05.008","article-title":"Prevalence and clinical presentation of food protein-induced enterocolitis syndrome in an adult allergy\/immunology clinic","volume":"133","author":"Buckey","year":"2024","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0031","article-title":"Adults with FPIES may face delayed diagnoses","volume":"3","author":"Hua","year":"2024","journal-title":"J Allergy Clin Immunol Glob"},{"issue":"1","key":"10.1016\/j.anai.2025.10.003_bib0032","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s13223-020-00497-z","article-title":"Adults with possible food protein-induced enterocolitis syndrome with crustacean ingestion","volume":"16","author":"Li","year":"2020","journal-title":"Allergy Asthma Clin Immunol"},{"issue":"5","key":"10.1016\/j.anai.2025.10.003_bib0033","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.anai.2021.02.006","article-title":"Food protein-induced enterocolitis syndrome epidemiology","volume":"126","author":"Cianferoni","year":"2021","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"11","key":"10.1016\/j.anai.2025.10.003_bib0034","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1016\/j.jaip.2022.08.038","article-title":"The natural history of food protein-induced enterocolitis syndrome (FPIES) in adults","volume":"10","author":"Graham","year":"2022","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0035","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.jaip.2025.02.007","article-title":"The heterogeneity of food protein-induced enterocolitis syndrome in adults","volume":"13","author":"Huang","year":"2025","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"3","key":"10.1016\/j.anai.2025.10.003_bib0036","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.jaip.2014.02.002","article-title":"Non-IgE-mediated gastrointestinal food hypersensitivity syndrome in adults","volume":"2","author":"Tan","year":"2014","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"6","key":"10.1016\/j.anai.2025.10.003_bib0037","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.anai.2018.08.003","article-title":"FPIES in adults","volume":"121","author":"Du","year":"2018","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"2","key":"10.1016\/j.anai.2025.10.003_bib0038","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.jaip.2018.07.028","article-title":"Food protein-induced enterocolitis-like syndrome in a population of adolescents and adults caused by seafood","volume":"7","author":"Gonzalez-Delgado","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"2","key":"10.1016\/j.anai.2025.10.003_bib0039","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.alit.2024.02.001","article-title":"Heterogeneity of food protein-induced enterocolitis syndrome (FPIES)","volume":"73","author":"Akashi","year":"2024","journal-title":"Allergol Int"},{"issue":"3","key":"10.1016\/j.anai.2025.10.003_bib0040","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1586\/eci.11.13","article-title":"Current understanding of the immune mechanisms of food protein-induced enterocolitis syndrome","volume":"7","author":"Caubet","year":"2011","journal-title":"Expert Rev Clin Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.10.003_bib0041","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1016\/j.jaci.2016.12.971","article-title":"Systemic innate immune activation in food protein-induced enterocolitis syndrome","volume":"139","author":"Goswami","year":"2017","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"10.1016\/j.anai.2025.10.003_bib0042","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.jaci.2022.09.035","article-title":"Untargeted serum metabolomic analysis reveals a role for purinergic signaling in FPIES","volume":"151","author":"Lozano-Ojalvo","year":"2023","journal-title":"J Allergy Clin Immunol"},{"issue":"5","key":"10.1016\/j.anai.2025.10.003_bib0043","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.jaci.2013.06.021","article-title":"Use of ondansetron for food protein-induced enterocolitis syndrome","volume":"132","author":"Holbrook","year":"2013","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.anai.2025.10.003_bib0044","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1159\/000363384","article-title":"Ondansetron for food protein-induced enterocolitis syndrome","volume":"164","author":"Miceli Sopo","year":"2014","journal-title":"Int Arch Allergy Immunol"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0045","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/all.13033","article-title":"Ondansetron in acute food protein-induced enterocolitis syndrome, a retrospective case-control study","volume":"72","author":"Miceli Sopo","year":"2017","journal-title":"Allergy"},{"issue":"6","key":"10.1016\/j.anai.2025.10.003_bib0046","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.anai.2025.02.015","article-title":"Where to challenge?: that is the question","volume":"134","author":"Bartnikas","year":"2025","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"2","key":"10.1016\/j.anai.2025.10.003_bib0047","doi-asserted-by":"crossref","first-page":"AB208","DOI":"10.1016\/j.jaci.2021.12.682","article-title":"Oral food challenge in adults with food protein-induced enterocolitis syndrome: a case series","volume":"149","author":"Perez-Pallise","year":"2022","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"10.1016\/j.anai.2025.10.003_bib0048","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.aller.2018.07.006","article-title":"Cooking influence in tolerance acquisition in egg-induced acute food protein enterocolitis syndrome","volume":"47","author":"Miceli Sopo","year":"2019","journal-title":"Allergol Immunopathol (Madr)"},{"issue":"1","key":"10.1016\/j.anai.2025.10.003_bib0049","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.jaip.2022.10.013","article-title":"Tolerability of baked milk consumption in children with food protein-induced enterocolitis syndrome","volume":"11","author":"Faitelson","year":"2023","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0050","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.jaip.2024.12.033","article-title":"Oral food challenge protocols in food protein-induced enterocolitis syndrome: a systematic review","volume":"13","author":"Ibrahim","year":"2025","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"5","key":"10.1016\/j.anai.2025.10.003_bib0051","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/j.jaci.2012.06.017","article-title":"Food protein-induced enterocolitis syndrome can occur in adults","volume":"130","author":"Fernandes","year":"2012","journal-title":"J Allergy Clin Immunol"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0052","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/pai.12225","article-title":"Drug-induced enterocolitis syndrome (DIES)","volume":"25","author":"Novembre","year":"2014","journal-title":"Pediatr Allergy Immunol"},{"issue":"5","key":"10.1016\/j.anai.2025.10.003_bib0053","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.anai.2025.02.021","article-title":"Drug-induced enterocolitis syndrome to amoxicillin-clavulanic acid in an adult patient with markers of gastrointestinal inflammation","volume":"134","author":"Moshkovich","year":"2025","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0054","doi-asserted-by":"crossref","first-page":"266","DOI":"10.18176\/jiaci.0970","article-title":"Drug-induced enterocolitis syndrome due to acetaminophen in an adult: a call for diagnostic tools and accurate management","volume":"34","author":"Laiseca Garc\u00eda","year":"2024","journal-title":"J Investig Allergol Clin Immunol"},{"issue":"9","key":"10.1016\/j.anai.2025.10.003_bib0055","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1016\/j.jaip.2020.04.046","article-title":"Drug-induced enterocolitis syndrome (DIES) with pantoprazole in an adult patient","volume":"8","author":"Bouvette","year":"2020","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"4","key":"10.1016\/j.anai.2025.10.003_bib0056","doi-asserted-by":"crossref","first-page":"301","DOI":"10.18176\/jiaci.0500","article-title":"Drug-induced enterocolitis syndrome due to amoxicillin-clavulanic acid with good tolerance to penicillin","volume":"30","author":"Freundt Serpa","year":"2020","journal-title":"J Investig Allergol Clin Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.10.003_bib0057","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1016\/j.jaip.2017.03.024","article-title":"Drug-induced enterocolitis in an adult patient","volume":"5","author":"Garc\u00eda Rodr\u00edguez","year":"2017","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"3","key":"10.1016\/j.anai.2025.10.003_bib0058","doi-asserted-by":"crossref","first-page":"329","DOI":"10.21911\/aai.2024.578","article-title":"Drug-induced enterocolitis syndrome with amoxicillin- clavulanic acid and alternative beta lactam antibiotic","volume":"22","author":"Yorusun","year":"2024","journal-title":"Asthma Allergy Immunol"},{"issue":"1","key":"10.1016\/j.anai.2025.10.003_bib0059","doi-asserted-by":"crossref","first-page":"101","DOI":"10.24953\/turkjpediatr.2025.5461","article-title":"Drug-induced enterocolitis syndrome in children: report of two cases and a literature review","volume":"67","author":"\u00d6zer","year":"2025","journal-title":"Turk J Pediatr"},{"issue":"1","key":"10.1016\/j.anai.2025.10.003_bib0060","doi-asserted-by":"crossref","first-page":"123","DOI":"10.15586\/aei.v53i1.1202","article-title":"Drug-induced enterocolitis, a new condition under consideration","volume":"53","author":"Mar\u00edn","year":"2025","journal-title":"Allergol Immunopathol (Madr)"},{"issue":"9","key":"10.1016\/j.anai.2025.10.003_bib0061","doi-asserted-by":"crossref","first-page":"7880","DOI":"10.3390\/ijms24097880","article-title":"Drug-induced enterocolitis syndrome in children","volume":"24","author":"Di Filippo","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"suppl 27","key":"10.1016\/j.anai.2025.10.003_bib0062","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/pai.13630","article-title":"The history of the drug-induced enterocolitis syndrome","volume":"33","author":"Novembre","year":"2022","journal-title":"Pediatr Allergy Immunol"},{"issue":"5","key":"10.1016\/j.anai.2025.10.003_bib0063","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.anai.2019.02.004","article-title":"Drug-induced enterocolitis syndrome (DIES): a clinical entity that deserves more awareness","volume":"122","author":"Van Thuijl","year":"2019","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"6","key":"10.1016\/j.anai.2025.10.003_bib0064","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1111\/pai.13491","article-title":"Drug-induced enterocolitis syndrome: similarities and differences compared with food protein-induced enterocolitis syndrome","volume":"32","author":"Mori","year":"2021","journal-title":"Pediatr Allergy Immunol"},{"issue":"2","key":"10.1016\/j.anai.2025.10.003_bib0065","doi-asserted-by":"crossref","DOI":"10.1111\/pai.13718","article-title":"T cell involvement in the pathogenesis of drug-induced enterocolitis syndrome","volume":"33","author":"Mori","year":"2022","journal-title":"Pediatr Allergy Immunol"},{"issue":"1","key":"10.1016\/j.anai.2025.10.003_bib0066","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.anai.2024.10.009","article-title":"Quality of life in adults with food protein-induced enterocolitis syndrome","volume":"134","author":"V\u00e1zquez-Barrera","year":"2025","journal-title":"Ann Allergy Asthma Immunol"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120625012360?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120625012360?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T09:30:44Z","timestamp":1765963844000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1081120625012360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":66,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S1081120625012360"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2025.10.003","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hard to digest","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2025.10.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}