{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T17:02:16Z","timestamp":1780333336074,"version":"3.54.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annales d'Endocrinologie"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.ando.2020.12.001","type":"journal-article","created":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T11:07:27Z","timestamp":1606907247000},"page":"36-42","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Analysis of steroid profiles by mass spectrometry: A new tool for exploring adrenal tumors?"],"prefix":"10.1016","volume":"82","author":[{"given":"Sophie","family":"Cambos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Chanson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Tabarin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ando.2020.12.001_bib0145","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1515\/cclm-2017-0806","article-title":"LC-MSMS assays of urinary cortisol, a comparison between four in-house assays","volume":"56","author":"Brossaud","year":"2018","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.ando.2020.12.001_bib0150","doi-asserted-by":"crossref","first-page":"3971","DOI":"10.1210\/jc.2013-3375","article-title":"Requirement for mass spectrometry sex steroid assays in the Journal of Clinical Endocrinology and Metabolism","volume":"98","author":"Handelsman","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2020.12.001_bib0155","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1373\/clinchem.2004.033605","article-title":"Quantitative, highly sensitive liquid chromatography-tandem mass spectrometry method for detection of synthetic corticosteroids","volume":"50","author":"Taylor","year":"2004","journal-title":"Clin Chem"},{"key":"10.1016\/j.ando.2020.12.001_bib0160","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1258\/acb.2011.011014","article-title":"Comparison of serum cortisol measurement by immunoassay and liquid chromatography-tandem mass spectrometry in patients receiving the 11\u03b2-hydroxylase inhibitor metyrapone","volume":"48","author":"Monaghan","year":"2011","journal-title":"Ann Clin Biochem"},{"key":"10.1016\/j.ando.2020.12.001_bib0165","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.jsbmb.2019.04.004","article-title":"Performance of LC-MS\/MS and immunoassay based 24-h urine free cortisol in the diagnosis of Cushing's syndrome","volume":"190","author":"O\u00dfwald","year":"2019","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.ando.2020.12.001_bib0170","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1373\/clinchem.2018.292201","article-title":"Using Machine Learning to Aid the Interpretation of Urine Steroid Profiles","volume":"64","author":"Wilkes","year":"2018","journal-title":"Clin Chem"},{"key":"10.1016\/j.ando.2020.12.001_bib0175","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1210\/jc.2005-2639","article-title":"Clinical review: adrenocortical carcinoma: clinical update","volume":"91","author":"Allolio","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2020.12.001_bib0180","doi-asserted-by":"crossref","first-page":"G1","DOI":"10.1530\/EJE-18-0608","article-title":"European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors","volume":"179","author":"Fassnacht","year":"2018","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.ando.2020.12.001_bib0185","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1159\/000184622","article-title":"Heterogeneity of urinary steroid profiles in children with adrenocortical tumors","volume":"44","author":"Ma\u0142unowicz","year":"1995","journal-title":"Horm Res"},{"key":"10.1016\/j.ando.2020.12.001_bib0190","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1507\/endocrj1954.32.29","article-title":"Measurement of urinary steroid profile in patients with adrenal tumor as a screening method for carcinoma","volume":"32","author":"Minowada","year":"1985","journal-title":"Endocrinol Jpn"},{"key":"10.1016\/j.ando.2020.12.001_bib0195","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1002\/1097-0142(19871001)60:7<1625::AID-CNCR2820600734>3.0.CO;2-M","volume":"60","author":"Doerr","year":"1987","journal-title":"Cancer"},{"key":"10.1016\/j.ando.2020.12.001_bib0200","doi-asserted-by":"crossref","first-page":"3775","DOI":"10.1210\/jc.2011-1565","article-title":"Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors","volume":"96","author":"Arlt","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2020.12.001_bib0205","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1007\/s12672-015-0224-3","article-title":"Diagnostic Value of Urinary Steroid Profiling in the Evaluation of Adrenal Tumors","volume":"6","author":"Kerkhofs","year":"2015","journal-title":"Horm Cancer"},{"key":"10.1016\/j.ando.2020.12.001_bib0210","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s12672-016-0267-0","article-title":"Different Types of Urinary Steroid Profiling Obtained by High-Performance Liquid Chromatography and Gas Chromatography-Mass Spectrometry in Patients with Adrenocortical Carcinoma","volume":"7","author":"Velikanova","year":"2016","journal-title":"Horm Cancer"},{"key":"10.1016\/j.ando.2020.12.001_bib0215","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1530\/EJE-18-0782","article-title":"Plasma steroid metabolome profiling for the diagnosis of adrenocortical carcinoma","volume":"180","author":"Schweitzer","year":"2019","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.ando.2020.12.001_bib0220","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S2213-8587(20)30218-7","article-title":"Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study","volume":"8","author":"Bancos","year":"2020","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.ando.2020.12.001_bib0225","doi-asserted-by":"crossref","first-page":"G1","DOI":"10.1530\/EJE-16-0467","article-title":"Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors","volume":"175","author":"Fassnacht","year":"2016","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.ando.2020.12.001_bib0230","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1530\/EJE-17-1056","article-title":"Diagnostic accuracy of computed tomography to identify adenomas among adrenal incidentalomas in an endocrinological population","volume":"178","author":"Marty","year":"2018","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.ando.2020.12.001_bib0235","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1530\/EJE-17-0078","article-title":"Simultaneous assay of cortisol and dexamethasone improved diagnostic accuracy of the dexamethasone suppression test","volume":"176","author":"Ueland G\u00c5","year":"2017","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.ando.2020.12.001_bib0240","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1210\/jc.2018-01029","article-title":"Is Frequently Unrelated to Autonomous Cortisol Secretion in Patients With Adrenal Incidentalomas","volume":"104","author":"Olsen","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2020.12.001_bib0245","doi-asserted-by":"crossref","first-page":"4331","DOI":"10.1210\/jc.2018-02349","article-title":"Plasma Steroid Profiles in Subclinical Compared With Overt Adrenal Cushing Syndrome","volume":"104","author":"Masjkur","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"10.1016\/j.ando.2020.12.001_bib0250","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1530\/EJE-11-1039","article-title":"Progressively increased patterns of subclinical cortisol hypersecretion in adrenal incidentalomas differently predict major metabolic and cardiovascular outcomes: a large cross-sectional study","volume":"166","author":"Di Dalmazi","year":"2012","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.ando.2020.12.001_bib0255","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/S2213-8587(13)70211-0","article-title":"Cardiovascular events and mortality in patients with adrenal incidentalomas that are either non-secreting or associated with intermediate phenotype or subclinical Cushing's syndrome: a 15-year retrospective study","volume":"2","author":"Di Dalmazi","year":"2014","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.ando.2020.12.001_bib0260","doi-asserted-by":"crossref","first-page":"4462","DOI":"10.1210\/jc.2014-3007","article-title":"Cortisol as a marker for increased mortality in patients with incidental adrenocortical adenomas","volume":"99","author":"Debono","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2020.12.001_bib0265","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1210\/jc.2013-3527","article-title":"Long-term follow-up in adrenal incidentalomas: an Italian multicenter study","volume":"99","author":"Morelli","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2020.12.001_bib0270","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1530\/EJE-17-0047","article-title":"Cardiovascular events in patients with mild autonomous cortisol secretion: analysis with artificial neural networks","volume":"177","author":"Morelli","year":"2017","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.ando.2020.12.001_bib0275","doi-asserted-by":"crossref","first-page":"5519","DOI":"10.1210\/jc.2019-00365","article-title":"The Steroid Profile of Adrenal Incidentalomas: Subtyping Subjects With High Cardiovascular Risk","volume":"104","author":"Di Dalmazi","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2020.12.001_bib0280","doi-asserted-by":"crossref","first-page":"e93136","DOI":"10.1172\/jci.insight.93136","article-title":"Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism","volume":"2","author":"Arlt","year":"2017","journal-title":"JCI Insight"}],"container-title":["Annales d'Endocrinologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003426620313032?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003426620313032?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T22:53:12Z","timestamp":1757717592000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003426620313032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["S0003426620313032"],"URL":"https:\/\/doi.org\/10.1016\/j.ando.2020.12.001","relation":{},"ISSN":["0003-4266"],"issn-type":[{"value":"0003-4266","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analysis of steroid profiles by mass spectrometry: A new tool for exploring adrenal tumors?","name":"articletitle","label":"Article Title"},{"value":"Annales d'Endocrinologie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ando.2020.12.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}]}}