{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:47:59Z","timestamp":1792799279431,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T00:00:00Z","timestamp":1720828800000},"content-version":"am","delay-in-days":347,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100014382","name":"Ipsen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014382","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annales d'Endocrinologie"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.ando.2023.04.001","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T20:24:31Z","timestamp":1681849471000},"page":"460-465","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["New directions in the treatment of hypoparathyroidism"],"prefix":"10.1016","volume":"84","author":[{"given":"Illias","family":"Hamny","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Chanson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Borson-Chazot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ando.2023.04.001_bib0155","doi-asserted-by":"crossref","first-page":"17055","DOI":"10.1038\/nrdp.2017.55","article-title":"Hypoparathyroidism","volume":"3","author":"Mannstadt","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.ando.2023.04.001_bib0160","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1210\/clinem\/dgaa113","article-title":"Hypoparathyroidism","volume":"105","author":"Bilezikian","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2023.04.001_bib0165","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1056\/NEJM200012213432508","article-title":"Hyperparathyroid and hypoparathyroid disorders","volume":"343","author":"Marx","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ando.2023.04.001_bib0170","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1001\/archotol.1988.01860140066023","article-title":"Temporary postthyroidectomy hypocalcemia","volume":"114","author":"Falk","year":"1988","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.ando.2023.04.001_bib0175","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1067\/msy.2003.61","article-title":"The impact of surgical technique on postoperative hypoparathyroidism in bilateral thyroid surgery: a multivariate analysis of 5846 consecutive patients","volume":"133","author":"Thomusch","year":"2003","journal-title":"Surgery"},{"key":"10.1016\/j.ando.2023.04.001_bib0180","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1056\/NEJMra030158","article-title":"Autoimmune polyendocrine syndromes","volume":"350","author":"Eisenbarth","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ando.2023.04.001_bib0185","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.ecl.2009.01.001","article-title":"Anti-parathyroid and anti-calcium sensing receptor antibodies in autoimmune hypoparathyroidism","volume":"38","author":"Brown","year":"2009","journal-title":"Endocrinol Metab Clin North Am"},{"key":"10.1016\/j.ando.2023.04.001_bib0190","doi-asserted-by":"crossref","first-page":"104","DOI":"10.4158\/EP10241.CR","article-title":"Proton pump inhibitor-induced hypocalcemic seizure in a patient with hypoparathyroidism","volume":"17","author":"Milman","year":"2011","journal-title":"Endocr Pract"},{"key":"10.1016\/j.ando.2023.04.001_bib0195","first-page":"642","article-title":"Endocrine complications in patients with thalassaemia major","volume":"5","author":"Toumba","year":"2007","journal-title":"Pediatr Endocrinol Rev"},{"key":"10.1016\/j.ando.2023.04.001_bib0200","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1111\/cen.12948","article-title":"Pseudohypoparathyroidism\u00a0\u2013\u00a0epidemiology, mortality and risk of complications","volume":"84","author":"Underbjerg","year":"2016","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.ando.2023.04.001_bib0205","first-page":"4236","article-title":"Control of pulsatile and tonic parathyroid hormone secretion by ionized calcium","volume":"81","author":"Schmitt","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2023.04.001_bib0210","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1002\/jbmr.483","article-title":"Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research","volume":"26","author":"Bilezikian","year":"2011","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.ando.2023.04.001_bib0215","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1530\/eje.0.1460215","article-title":"Well-being, mood and calcium homeostasis in patients with hypoparathyroidism receiving standard treatment with calcium and vitamin D","volume":"146","author":"Arlt","year":"2002","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.ando.2023.04.001_bib0220","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1530\/EJE-12-0946","article-title":"Neuropsychological dysfunction in idiopathic hypoparathyroidism and its relationship with intracranial calcification and serum total calcium","volume":"168","author":"Aggarwal","year":"2013","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.ando.2023.04.001_bib0225","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/0002-9343(89)90338-0","article-title":"Normal left ventricular performance documented by Doppler echocardiography in patients with long-standing hypocalcemia","volume":"86","author":"Vered","year":"1989","journal-title":"Am J Med"},{"key":"10.1016\/j.ando.2023.04.001_bib0230","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1002\/jbmr.2501","article-title":"The epidemiology of nonsurgical hypoparathyroidism in Denmark: a nationwide case finding study","volume":"30","author":"Underbjerg","year":"2015","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.ando.2023.04.001_bib0235","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1002\/jbmr.1979","article-title":"Cardiovascular and renal complications to postsurgical hypoparathyroidism: a Danish nationwide controlled historic follow-up study","volume":"28","author":"Underbjerg","year":"2013","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.ando.2023.04.001_bib0240","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1007\/s12325-021-01649-2","article-title":"Risk of nephrolithiasis and nephrocalcinosis in patients with chronic hypoparathyroidism: a retrospective cohort study","volume":"38","author":"Ketteler","year":"2021","journal-title":"Adv Ther"},{"key":"10.1016\/j.ando.2023.04.001_bib0245","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s11154-020-09613-1","article-title":"Renal complications in patients with chronic hypoparathyroidism on conventional therapy: a systematic literature review: renal disease in chronic hypoparathyroidism","volume":"22","author":"Gosmanova","year":"2021","journal-title":"Rev Endocr Metab Disord"},{"key":"10.1016\/j.ando.2023.04.001_bib0250","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/bcp.13455","article-title":"Optimal dosing and delivery of parathyroid hormone and its analogues for osteoporosis and hypoparathyroidism\u00a0\u2013\u00a0translating the pharmacology","volume":"84","author":"Tay","year":"2018","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.ando.2023.04.001_bib0255","doi-asserted-by":"crossref","first-page":"4214","DOI":"10.1210\/jc.2002-021736","article-title":"Long-term treatment of hypoparathyroidism: a randomized controlled study comparing parathyroid hormone-(1-34) versus calcitriol and calcium","volume":"88","author":"Winer","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2023.04.001_bib0260","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.bone.2018.09.018","article-title":"Advances in the treatment of hypoparathyroidism with PTH 1-34","volume":"120","author":"Winer","year":"2019","journal-title":"Bone"},{"key":"10.1016\/j.ando.2023.04.001_bib0265","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S2213-8587(13)70106-2","article-title":"Efficacy and safety of recombinant human parathyroid hormone (1-84) in hypoparathyroidism (REPLACE): a double-blind, placebo-controlled, randomised, phase 3 study","volume":"1","author":"Mannstadt","year":"2013","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.ando.2023.04.001_bib0270","doi-asserted-by":"crossref","first-page":"5601","DOI":"10.1210\/jc.2019-00893","article-title":"Therapy of hypoparathyroidism with rhPTH(1-84): a prospective, 8-year investigation of efficacy and safety","volume":"104","author":"Tay","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2023.04.001_bib0275","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1002\/jbmr.4566","article-title":"Safety and efficacy of PTH 1-34 and 1-84 therapy in chronic hypoparathyroidism: a meta-analysis of prospective trials","volume":"37","author":"Puliani","year":"2022","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.ando.2023.04.001_bib0280","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1002\/jbmr.4016","article-title":"A randomized double-blind placebo-controlled first-in-human phase 1 trial of transcon PTH in healthy adults","volume":"35","author":"Karpf","year":"2020","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.ando.2023.04.001_bib0285","doi-asserted-by":"crossref","first-page":"e372","DOI":"10.1210\/clinem\/dgab577","article-title":"Path forward: a randomized, double-blind, placebo-controlled phase 2 trial of transcon PTH in adult hypoparathyroidism","volume":"107","author":"Khan","year":"2022","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ando.2023.04.001_bib0290","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1038\/nrendo.2015.139","article-title":"PTH receptor-1 signalling-mechanistic insights and therapeutic prospects","volume":"11","author":"Cheloha","year":"2015","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.ando.2023.04.001_bib0295","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1002\/jbmr.2811","article-title":"Pharmacodynamic actions of a long-acting PTH analog (LA-PTH) in thyroparathyroidectomized (TPTX) rats and normal monkeys","volume":"31","author":"Shimizu","year":"2016","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.ando.2023.04.001_bib0300","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1258\/0004563042466802","article-title":"Clinical and laboratory features of calcium-sensing receptor disorders: a systematic review","volume":"41","author":"Gunn","year":"2004","journal-title":"Ann Clin Biochem"}],"container-title":["Annales d'Endocrinologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003426623000781?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003426623000781?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T22:54:53Z","timestamp":1757717693000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003426623000781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["S0003426623000781"],"URL":"https:\/\/doi.org\/10.1016\/j.ando.2023.04.001","relation":{},"ISSN":["0003-4266"],"issn-type":[{"value":"0003-4266","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"New directions in the treatment of hypoparathyroidism","name":"articletitle","label":"Article Title"},{"value":"Annales d'Endocrinologie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ando.2023.04.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}