{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T22:00:33Z","timestamp":1783116033486,"version":"3.54.6"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Internacional de Androlog\u00eda"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.androl.2019.04.003","type":"journal-article","created":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T05:20:24Z","timestamp":1563427224000},"page":"137-143","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Is there any relationship between human sperm parameters and protamine deficiency in different groups of infertile men?"],"prefix":"10.1016","volume":"18","author":[{"given":"Fatemeh","family":"Dehghanpour","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzaneh","family":"Fesahat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Yazdinejad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Motamedzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Reza","family":"Talebi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.androl.2019.04.003_bib0135","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1093\/humupd\/dml057","article-title":"Altered protamine expression and diminished spermatogenesis: what is the link?","volume":"13","author":"Carrell","year":"2007","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.androl.2019.04.003_bib0140","doi-asserted-by":"crossref","unstructured":"Oliva R. Protamines and male infertility. Hum Reprod Update. https:\/\/academic.oup.com\/humupd\/article-abstract\/12\/4\/417\/2182165 [accessed 11.07.18].","DOI":"10.1093\/humupd\/dml009"},{"key":"10.1016\/j.androl.2019.04.003_bib0145","article-title":"A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcome","author":"Simon","year":"2017","journal-title":"Asian J Androl"},{"key":"10.1016\/j.androl.2019.04.003_bib0150","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1111\/j.2047-2927.2013.00138.x","article-title":"Specific sperm defects are differentially correlated with DNA fragmentation in both normozoospermic and teratozoospermic subjects","volume":"1","author":"Mangiarini","year":"2013","journal-title":"Andrology"},{"key":"10.1016\/j.androl.2019.04.003_bib0155","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s00404-009-1140-y","article-title":"Sperm morphological abnormalities as indicators of DNA fragmentation and fertilization in ICSI","volume":"281","author":"Dari\u0161","year":"2010","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.androl.2019.04.003_bib0160","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.rbmo.2014.02.004","article-title":"damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility","volume":"28","author":"Wright","year":"2014","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.androl.2019.04.003_bib0165","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1111\/andr.12216","article-title":"The impact of sperm protamine deficiency and sperm DNA damage on human male fertility: a systematic review and meta-analysis","volume":"4","author":"Ni","year":"2016","journal-title":"Andrology"},{"key":"10.1016\/j.androl.2019.04.003_bib0170","doi-asserted-by":"crossref","DOI":"10.1038\/aja.2010.68","article-title":"Apoptosis and DNA damage in human spermatozoa","author":"Aitken","year":"2011","journal-title":"Asian J Androl"},{"key":"10.1016\/j.androl.2019.04.003_bib0175","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/and.12114","article-title":"Quality of human spermatozoa: relationship between high-magnification sperm morphology and DNA integrity","volume":"46","author":"Maettner","year":"2014","journal-title":"Andrologia"},{"key":"10.1016\/j.androl.2019.04.003_bib0180","series-title":"WHO laboratory manual for the examination and processing of human semen","year":"2010"},{"key":"10.1016\/j.androl.2019.04.003_bib0185","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.ucl.2008.01.012","article-title":"Assessing sperm function","volume":"35","author":"Agarwal","year":"2008","journal-title":"Urol Clin North Am"},{"key":"10.1016\/j.androl.2019.04.003_bib0190","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1111\/and.12156","article-title":"Total globozoospermia associated with increased frequency of immature spermatozoa with chromatin defects and aneuploidy: a case report","volume":"46","author":"Vozdova","year":"2014","journal-title":"Andrologia"},{"key":"10.1016\/j.androl.2019.04.003_bib0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1439-0272.2012.01308.x","article-title":"Molecular cytogenetic and genetic aspects of globozoospermia: a review","volume":"45","author":"Perrin","year":"2013","journal-title":"Andrologia"},{"key":"10.1016\/j.androl.2019.04.003_bib0200","doi-asserted-by":"crossref","first-page":"17","DOI":"10.5653\/cerm.2018.45.1.17","article-title":"www.eCERM.org Sperm chromatin and DNA integrity, methyltransferase mRNA levels, and global DNA methylation in oligoasthenoteratozoospermia","volume":"45","author":"Rahiminia","year":"2018","journal-title":"Clin Exp Reprod Med"},{"key":"10.1016\/j.androl.2019.04.003_bib0205","doi-asserted-by":"crossref","DOI":"10.5653\/cerm.2017.44.2.73","article-title":"Evaluation of sperm protamine deficiency and apoptosis in infertile men with idiopathic teratozoospermia","volume":"44","author":"Dehghanpour","year":"2017","journal-title":"Clin Exp Reprod Med"},{"key":"10.1016\/j.androl.2019.04.003_bib0210","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.fertnstert.2005.08.024","article-title":"Significance of sperm characteristics in the evaluation of male infertility: significance of sperm characteristics in the evaluation of male infertility","volume":"85","author":"Clinic","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1016\/j.androl.2019.04.003_bib0215","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1007\/s10815-014-0194-3","article-title":"Which isolated sperm abnormality is most related to sperm DNA damage in men presenting for infertility evaluation","volume":"31","author":"Belloc","year":"2014","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.androl.2019.04.003_bib0220","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1007\/s10815-011-9631-8","article-title":"Sperm DNA integrity assays: diagnostic and prognostic challenges and implications in management of infertility","volume":"28","author":"Shamsi","year":"2011","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.androl.2019.04.003_bib0225","doi-asserted-by":"crossref","DOI":"10.1095\/biolreprod66.4.1061","article-title":"Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis","author":"Sakkas","year":"2002","journal-title":"Biol Reprod"},{"key":"10.1016\/j.androl.2019.04.003_bib0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2006.04.023","article-title":"Global sperm deoxyribonucleic acid methylation is unaffected in protamine-deficient infertile males","author":"Aoki","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1016\/j.androl.2019.04.003_bib0235","doi-asserted-by":"crossref","DOI":"10.1038\/ng0501-82","article-title":"Haploinsufficiency of protamine-1 or-2 causes infertility in mice","author":"Cho","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.androl.2019.04.003_bib0240","doi-asserted-by":"crossref","DOI":"10.1111\/and.12823","article-title":"Sperm chromatin quality and DNA integrity in partial versus total globozoospermia","volume":"50","author":"Talebi","year":"2018","journal-title":"Andrologia"},{"key":"10.1016\/j.androl.2019.04.003_bib0245","article-title":"Sperm parameters, protamine deficiency, and apoptosis in total globozoospermia","volume":"13","author":"Ghasemzadeh","year":"2015","journal-title":"Iran J Reprod Med"},{"key":"10.1016\/j.androl.2019.04.003_bib0250","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.aju.2017.11.002","article-title":"Role of sperm DNA fragmentation in male factor infertility: a systematic review","volume":"16","author":"Cho","year":"2018","journal-title":"Arab J Urol"},{"key":"10.1016\/j.androl.2019.04.003_bib0255","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1016\/j.fertnstert.2015.08.028","article-title":"Comparison of reproductive outcome in oligozoospermic men with high sperm DNA fragmentation undergoing intracytoplasmic sperm injection with ejaculated and testicular sperm","volume":"104","author":"Esteves","year":"2015","journal-title":"Fertil Steril"},{"key":"10.1016\/j.androl.2019.04.003_bib0260","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/j.fertnstert.2015.08.008","article-title":"Higher pregnancy rates using testicular sperm in men with severe oligospermia","volume":"104","author":"Mehta","year":"2015","journal-title":"Fertil Steril"}],"container-title":["Revista Internacional de Androlog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1698031X19300391?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1698031X19300391?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T23:02:54Z","timestamp":1602198174000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1698031X19300391"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["S1698031X19300391"],"URL":"https:\/\/doi.org\/10.1016\/j.androl.2019.04.003","relation":{},"ISSN":["1698-031X"],"issn-type":[{"value":"1698-031X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is there any relationship between human sperm parameters and protamine deficiency in different groups of infertile men?","name":"articletitle","label":"Article Title"},{"value":"Revista Internacional de Androlog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.androl.2019.04.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Espa\u00f1a, S.L.U. on behalf of Asociaci\u00f3n Espa\u00f1ola de Androlog\u00eda, Medicina Sexual y Reproductiva.","name":"copyright","label":"Copyright"}]}}