{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T13:09:36Z","timestamp":1755695376731},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Internacional de Androlog\u00eda"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.androl.2020.10.001","type":"journal-article","created":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T13:49:34Z","timestamp":1624369774000},"page":"S17-S23","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"S1","title":["Effect of sunitinib on testicular oxidative and proinflammatory damage induced by ischemia\u2013reperfusion in rats"],"prefix":"10.1016","volume":"20","author":[{"given":"Ercument","family":"Keskin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Erdogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halis","family":"Suleyman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gulce Naz","family":"Yazici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mukadder","family":"Sunar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Ali","family":"Gul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.androl.2020.10.001_bib0140","doi-asserted-by":"crossref","first-page":"2574","DOI":"10.1097\/01.ju.0000144203.30718.19","article-title":"The molecular pathology of experimental testicular torsion suggests adjunct therapy to surgical repair","volume":"172","author":"Turner","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.androl.2020.10.001_bib0145","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/j.1939-4640.1995.tb01724.x","article-title":"Leydig cell function after experimental testicular torsion despite loss of spermatogenesis","volume":"16","author":"Baker","year":"1995","journal-title":"J Androl"},{"key":"10.1016\/j.androl.2020.10.001_bib0150","article-title":"Protective effect of hydrogen sulphite on experimental testicular ischemia reperfusion in rats","author":"Bozkurt","year":"2019","journal-title":"J Pediatr Urol"},{"key":"10.1016\/j.androl.2020.10.001_bib0155","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/jdv.12615","article-title":"Scrotal cutaneous toxicity: an uncommon but important side-effect of sunitinib","volume":"30","author":"Gupta","year":"2016","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.androl.2020.10.001_bib0160","first-page":"5035217","article-title":"Stomatitis and VEGFR-tyrosine kinase inhibitors (VR-TKIs): a review of current literature in 4369 patients","volume":"24","author":"Arena","year":"2018","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.androl.2020.10.001_bib0165","doi-asserted-by":"crossref","unstructured":"Suddek GM. Sunitinib improves chemotherapeutic efficacy and ameliorates cisplatin-induced nephrotoxicity in experimental animals. Cancer Chemother Pharmacol 2011;67:1035\u201344.","DOI":"10.1007\/s00280-010-1402-1"},{"key":"10.1016\/j.androl.2020.10.001_bib0170","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.molonc.2012.06.006","article-title":"Blockade of NF\u03baB activity by Sunitinib increases cell death in Bortezomib-treated endometrial carcinoma cells","volume":"6","author":"Sorolla","year":"2012","journal-title":"Mol Oncol"},{"key":"10.1016\/j.androl.2020.10.001_bib0175","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/nprot.2009.197","article-title":"Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue","volume":"5","author":"Weydert","year":"2010","journal-title":"Nat Protoc"},{"key":"10.1016\/j.androl.2020.10.001_bib0180","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1016\/j.androl.2020.10.001_bib0185","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal Biochem"},{"key":"10.1016\/j.androl.2020.10.001_bib0190","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0003-2697(68)90092-4","article-title":"Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent","volume":"25","author":"Sedlak","year":"1968","journal-title":"Anal Biochem"},{"key":"10.1016\/j.androl.2020.10.001_bib0195","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/S0022-5347(17)49278-0","article-title":"Histological changes occurring in the contralateral testes of prepubertal rats subjected to various durations of unilateral spermatic cord torsion","volume":"133","author":"Cosentino","year":"1985","journal-title":"J Urol"},{"key":"10.1016\/j.androl.2020.10.001_bib0200","series-title":"Mechanisms of oxygen activation and reactive oxygen species detoxification","first-page":"4","author":"Cadenas","year":"1995"},{"key":"10.1016\/j.androl.2020.10.001_bib0205","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1016\/S0022-5347(01)64420-3","article-title":"A platelet activating factor antagonist attenuates the effects of testicular ischemia","volume":"158","author":"Palmer","year":"1997","journal-title":"J Urol"},{"key":"10.1016\/j.androl.2020.10.001_bib0210","first-page":"8","article-title":"The effects of \u03b1-lipoik acid against testicular ischemia\u2013reperfusion injury in rats","author":"Ozbal","year":"2012","journal-title":"Sci World J"},{"key":"10.1016\/j.androl.2020.10.001_bib0215","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.biopha.2017.12.093","article-title":"Upregulation of peroxisome proliferator activated receptor alpha by fenofibrate in induced testicular ischemia reperfusion","volume":"27","author":"Refaie","year":"2018","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.androl.2020.10.001_bib0220","article-title":"The investigation of the protective effects of nimesulide on experimental testicular ischemia\u2013reperfusion injury in rats","author":"Polat","year":"2018","journal-title":"Rev Int Androl"},{"key":"10.1016\/j.androl.2020.10.001_bib0225","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1093\/oxfordjournals.bmb.a072641","article-title":"Prospects for treatment of free radical-mediated tissue injury","volume":"49","author":"Rangan","year":"1993","journal-title":"Br Med Bull"},{"issue":"Suppl. 1","key":"10.1016\/j.androl.2020.10.001_bib0230","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1590\/S0102-86502011000700005","article-title":"l-Alanyl-glutamine dipeptide pretreatment attenuates ischemia\u2013reperfusion injury in rat testis","volume":"26","author":"Leitao","year":"2011","journal-title":"Acta Cir Bras"},{"issue":"Suppl. 1","key":"10.1016\/j.androl.2020.10.001_bib0235","doi-asserted-by":"crossref","first-page":"I19","DOI":"10.1002\/clc.4960161307","article-title":"Reactive oxygen metabolites, neutrophils, and the pathogenesis of ischemic-tissue\/reperfusion","volume":"16","author":"Korthuis","year":"1993","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.androl.2020.10.001_bib0240","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1095\/biolreprod.102.013318","article-title":"Ischemia\u2013reperfusion of the murine testis stimulates the expression of proinflammatory cytokines and activation of c-jun N-terminal kinase in a pathway to E-selectin expression","volume":"69","author":"Lysiak","year":"2003","journal-title":"Biol Reprod"},{"key":"10.1016\/j.androl.2020.10.001_bib0245","doi-asserted-by":"crossref","first-page":"6959274","DOI":"10.1155\/2016\/6959274","article-title":"Ginkgo Biloba ameliorates subfertility induced by testicular ischemia\/reperfusion injury in adult Wistar rats: a possible new mitochondrial mechanism","volume":"2016","author":"Ahmed","year":"2016","journal-title":"Oxid Med Cell Longev"},{"issue":"Pt 4","key":"10.1016\/j.androl.2020.10.001_bib0250","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1242\/jcs.00286","article-title":"VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2","volume":"116","author":"Kiriakidis","year":"2003","journal-title":"J Cell Sci"},{"key":"10.1016\/j.androl.2020.10.001_bib0255","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.bcp.2009.12.021","article-title":"Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action","volume":"1","author":"Miller","year":"2010","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.androl.2020.10.001_bib0260","first-page":"2702","article-title":"Selective nuclear factor kappa b (NFkB) inhibitor, pyrrolidium dithiocarbamate prevents, long-term histologic damage in ischemia\u2013reperfusion injuries after delayed testicular torsion","volume":"13","author":"Ozcan","year":"2016","journal-title":"Urol J"},{"key":"10.1016\/j.androl.2020.10.001_bib0265","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3109\/09513590.2015.1005593","article-title":"Therapeutic effect of sunitinib on diabetes mellitus related ovarian injury: an experimental rat model study","volume":"31","author":"Erbas","year":"2015","journal-title":"Gynecol Endocrinol"}],"container-title":["Revista Internacional de Androlog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1698031X21000133?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1698031X21000133?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,11,5]],"date-time":"2023-11-05T06:15:30Z","timestamp":1699164930000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1698031X21000133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":26,"alternative-id":["S1698031X21000133"],"URL":"https:\/\/doi.org\/10.1016\/j.androl.2020.10.001","relation":{},"ISSN":["1698-031X"],"issn-type":[{"value":"1698-031X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of sunitinib on testicular oxidative and proinflammatory damage induced by ischemia\u2013reperfusion in rats","name":"articletitle","label":"Article Title"},{"value":"Revista Internacional de Androlog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.androl.2020.10.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Asociaci\u00f3n Espa\u00f1ola de Androlog\u00eda, Medicina Sexual y Reproductiva. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}