{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T05:44:06Z","timestamp":1781329446913,"version":"3.54.1"},"reference-count":19,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Internacional de Androlog\u00eda"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.androl.2023.100349","type":"journal-article","created":{"date-parts":[[2023,4,11]],"date-time":"2023-04-11T10:09:22Z","timestamp":1681207762000},"page":"100349","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Klinefelter syndrome: The characterization of the clinical and sociological features of 51 patients"],"prefix":"10.1016","volume":"21","author":[{"given":"Fernando","family":"Mendon\u00e7a","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selma","family":"Souto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"D\u00f3ria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.androl.2023.100349_bib0100","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1210\/jc.2012-2382","article-title":"Klinefelter syndrome\u2014a clinical update","volume":"98","author":"Groth","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.androl.2023.100349_bib0105","series-title":"Klinefelter's syndrome: from a disabling condition to a variant of normalcy","year":"2020"},{"key":"10.1016\/j.androl.2023.100349_bib0110","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1159\/000327324","article-title":"Chromosomal variants in Klinefelter syndrome","volume":"5","author":"Fr\u00fchmesser","year":"2011","journal-title":"Sex Dev"},{"key":"10.1016\/j.androl.2023.100349_bib0115","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1002\/rmb2.12261","article-title":"Klinefelter syndrome: from pediatrics to geriatrics","volume":"18","author":"Shiraishi","year":"2019","journal-title":"Reprod Med Biol"},{"key":"10.1016\/j.androl.2023.100349_bib0120","first-page":"324835","article-title":"Clinical presentation of Klinefelter's syndrome: differences according to age","author":"Pacenza","year":"2012","journal-title":"Int J Endocrinol"},{"key":"10.1016\/j.androl.2023.100349_bib0125","author":"Alvin","year":"2020","journal-title":"Clinical features, diagnosis, and management of Klinefelter syndrome"},{"key":"10.1016\/j.androl.2023.100349_bib0195","first-page":"312","article-title":"Klinefelter syndrome in children - endocrine and behavioral aspects","volume":"114","author":"Carvalho","year":"1986","journal-title":"O M\u00e9dico."},{"key":"10.1016\/j.androl.2023.100349_bib0135","article-title":"Preval\u00eancia de excesso de peso e de obesidade em Portugal: resultados do primeiro Inqu\u00e9rito Nacional de Sa\u00fade com Exame F\u00edsico (INSEF 2015)","author":"V\u00e2nia Gaio","year":"2018","journal-title":"Boletim epidemiol\u00f3gico: observa\u00e7\u00f5es"},{"key":"10.1016\/j.androl.2023.100349_bib0140","first-page":"347","article-title":"Klinefelter syndrome: the commonest form of hypogonadism, but often overlooked or untreated","volume":"110","author":"Nieschlag","year":"2013","journal-title":"Dtsch Arztebl Int"},{"key":"10.1016\/j.androl.2023.100349_bib0145","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s40618-016-0541-6","article-title":"Klinefelter syndrome (KS): genetics, clinical phenotype and hypogonadism","volume":"40","author":"Bonomi","year":"2017","journal-title":"J Endocrinol Invest"},{"key":"10.1016\/j.androl.2023.100349_bib0150","doi-asserted-by":"crossref","first-page":"6516","DOI":"10.1210\/jc.2005-1077","article-title":"Mortality in patients with Klinefelter syndrome in Britain: a cohort study","volume":"90","author":"Swerdlow","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.androl.2023.100349_bib0155","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1111\/j.1651-2227.2011.02246.x","article-title":"Clinical and biological parameters in 166 boys, adolescents and adults with nonmosaic Klinefelter syndrome: a Copenhagen experience","volume":"100","author":"Aksglaede","year":"2011","journal-title":"Acta Paediatr (Oslo, Norway: 1992)"},{"key":"10.1016\/j.androl.2023.100349_bib0160","doi-asserted-by":"crossref","first-page":"263","DOI":"10.4103\/ijem.IJEM_582_18","article-title":"Klinefelter syndrome: clinical spectrum based on 44 consecutive cases from a South Indian Tertiary Care Center","volume":"23","author":"Asirvatham","year":"2019","journal-title":"Indian J Endocrinol Metab"},{"key":"10.1016\/j.androl.2023.100349_bib0165","doi-asserted-by":"crossref","first-page":"323","DOI":"10.2223\/JPED.2208","article-title":"S\u00edndrome de Klinefelter: diagn\u00f3stico raro na faixa et\u00e1ria pedi\u00e1trica","volume":"88","author":"Tincani","year":"2012","journal-title":"J Pediatr (Rio J)"},{"key":"10.1016\/j.androl.2023.100349_bib0170","first-page":"3","article-title":"Klinefelter Syndrome in adults: variability in clinical findings","volume":"15","author":"Barbosa","year":"2020","journal-title":"Rev Port Endocrinol Diabetes Metab"},{"key":"10.1016\/j.androl.2023.100349_bib0175","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1210\/er.2017-00212","article-title":"Klinefelter syndrome: integrating genetics, neuropsychology, and endocrinology","volume":"39","author":"Gravholt","year":"2018","journal-title":"Endocr Rev"},{"key":"10.1016\/j.androl.2023.100349_bib0180","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0206932","article-title":"Anxiety and depression in Klinefelter syndrome: the impact of personality and social engagement","volume":"13","author":"Skakkeb\u00e6k","year":"2018","journal-title":"PLOS ONE"},{"key":"10.1016\/j.androl.2023.100349_bib0185","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1007\/BF03350351","article-title":"Consensus statement on diagnosis and clinical management of Klinefelter syndrome","volume":"33","author":"Radicioni","year":"2010","journal-title":"J Endocrinol Invest"},{"key":"10.1016\/j.androl.2023.100349_bib0190","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1093\/humupd\/dmx008","article-title":"Sperm recovery and ICSI outcomes in Klinefelter syndrome: a systematic review and meta-analysis","volume":"23","author":"Corona","year":"2017","journal-title":"Hum Reprod Update"}],"container-title":["Revista Internacional de Androlog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1698031X23000092?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1698031X23000092?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T17:42:35Z","timestamp":1687887755000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1698031X23000092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["S1698031X23000092"],"URL":"https:\/\/doi.org\/10.1016\/j.androl.2023.100349","relation":{},"ISSN":["1698-031X"],"issn-type":[{"value":"1698-031X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Klinefelter syndrome: The characterization of the clinical and sociological features of 51 patients","name":"articletitle","label":"Article Title"},{"value":"Revista Internacional de Androlog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.androl.2023.100349","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Asociaci\u00f3n Espa\u00f1ola de Androlog\u00eda, Medicina Sexual y Reproductiva. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100349"}}