{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:57:36Z","timestamp":1792180656227,"version":"4.4.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31872385"],"award-info":[{"award-number":["31872385"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020198","name":"Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020198","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Animal Nutrition"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.aninu.2024.06.004","type":"journal-article","created":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T07:14:34Z","timestamp":1720941274000},"page":"13-24","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Sheep-derived butyrate-producing Clostridium beijerinckii R8 alleviates diarrhea by shaping the gut microbiota of goat kids"],"prefix":"10.1016","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-6836-0068","authenticated-orcid":false,"given":"Dingkun","family":"Fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuze","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jixian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanliang","family":"Bi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyu","family":"Diao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6272-7553","authenticated-orcid":false,"given":"Naifeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"24","key":"10.1016\/j.aninu.2024.06.004_bib1","doi-asserted-by":"crossref","first-page":"5323","DOI":"10.3390\/nu14245323","article-title":"Gut microbiota in non-alcoholic fatty liver disease patients with inflammatory bowel diseases: a complex interplay","volume":"14","author":"Abenavoli","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.aninu.2024.06.004_bib2","series-title":"Official methods of analysis. 15th ed. Washington DC","year":"1990"},{"issue":"Database issue","key":"10.1016\/j.aninu.2024.06.004_bib3","doi-asserted-by":"crossref","first-page":"D30","DOI":"10.1093\/nar\/gku1216","volume":"43","author":"Benson","year":"2015","journal-title":"GenBank. Nucleic Acids Res."},{"issue":"8","key":"10.1016\/j.aninu.2024.06.004_bib4","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/s41587-019-0209-9","article-title":"Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2","volume":"37","author":"Bolyen","year":"2019","journal-title":"Nat Biotechnol"},{"issue":"3","key":"10.1016\/j.aninu.2024.06.004_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.beem.2021.101504","article-title":"Next-generation therapeutic bacteria for treatment of obesity, diabetes, and other endocrine diseases","volume":"35","author":"Bui","year":"2021","journal-title":"Best Pract Res Clin Endocrinol Metabol"},{"issue":"5","key":"10.1016\/j.aninu.2024.06.004_bib6","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.1039\/C8FO02370K","article-title":"Positive effects of a Clostridium butyricum-based compound probiotic on growth performance, immune responses, intestinal morphology, hypothalamic neurotransmitters, and colonic microbiota in weaned piglets","volume":"10","author":"Cao","year":"2019","journal-title":"Food Funct"},{"key":"10.1016\/j.aninu.2024.06.004_bib7","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.canlet.2019.11.019","article-title":"Clostridium butyricum, a butyrate-producing probiotic, inhibits intestinal tumor development through modulating Wnt signaling and gut microbiota","volume":"469","author":"Chen","year":"2020","journal-title":"Cancer Lett"},{"key":"10.1016\/j.aninu.2024.06.004_bib8","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s40104-018-0275-8","article-title":"Effects of dietary Clostridium butyricum supplementation on growth performance, intestinal development, and immune response of weaned piglets challenged with lipopolysaccharide","volume":"9","author":"Chen","year":"2018","journal-title":"J\u00a0Anim Sci Biotechnol"},{"issue":"6","key":"10.1016\/j.aninu.2024.06.004_bib9","doi-asserted-by":"crossref","first-page":"5748","DOI":"10.3390\/ijms24065748","article-title":"Biotherapy using probiotics as therapeutic agents to restore the gut microbiota to relieve gastrointestinal tract inflammation, IBD, IBS and prevent induction of cancer","volume":"24","author":"Dahiya","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.aninu.2024.06.004_bib10","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/4464002","article-title":"Clostridium butyricum protects IPEC-J2 cells from ETEC K88-induced oxidative damage by activating the Nrf 2\/ARE signaling pathway","volume":"2021","author":"Dou","year":"2021","journal-title":"Oxid Med Cell Longev"},{"key":"10.1016\/j.aninu.2024.06.004_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.meatsci.2023.109235","article-title":"Supplemental Clostridium butyricum modulates skeletal muscle development and meat quality by shaping the gut microbiota of lambs","volume":"204","author":"Dou","year":"2023","journal-title":"Meat Sci"},{"issue":"6","key":"10.1016\/j.aninu.2024.06.004_bib12","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/s41587-020-0548-6","article-title":"PICRUSt2 for prediction of metagenome functions","volume":"38","author":"Douglas","year":"2020","journal-title":"Nat Biotechnol"},{"issue":"16","key":"10.1016\/j.aninu.2024.06.004_bib13","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1093\/bioinformatics\/btr381","article-title":"UCHIME improves sensitivity and speed of chimera detection","volume":"27","author":"Edgar","year":"2011","journal-title":"Bioinformatics"},{"issue":"3","key":"10.1016\/j.aninu.2024.06.004_bib14","doi-asserted-by":"crossref","first-page":"527","DOI":"10.3390\/cells10030527","article-title":"Clostridium butyricum ZJU-F1 benefits the intestinal barrier function and immune response associated with its modulation of gut microbiota in weaned piglets","volume":"10","author":"Fu","year":"2021","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.aninu.2024.06.004_bib15","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.cell.2010.01.023","article-title":"Homeostasis and inflammation in the intestine","volume":"140","author":"Garrett","year":"2010","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.aninu.2024.06.004_bib16","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.jcmgh.2021.02.007","article-title":"Regulation of intestinal barrier function by microbial metabolites","volume":"11","author":"Ghosh","year":"2021","journal-title":"Cell Mol Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.aninu.2024.06.004_bib17","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s40104-015-0014-3","article-title":"Study and use of the probiotic Lactobacillus reuteri in pigs: a review","volume":"6","author":"Hou","year":"2015","journal-title":"J\u00a0Anim Sci Biotechnol"},{"issue":"12","key":"10.1016\/j.aninu.2024.06.004_bib18","first-page":"2774","article-title":"Dietary sodium butyrate decreases postweaning diarrhea by modulating intestinal permeability and changing the bacterial communities in weaned piglets","volume":"145","author":"Huang","year":"2015","journal-title":"J\u00a0Nutr"},{"issue":"12","key":"10.1016\/j.aninu.2024.06.004_bib19","doi-asserted-by":"crossref","first-page":"5690","DOI":"10.1039\/D3FO01193C","article-title":"Fecal microbiota transplantation from sodium alginate-dosed mice and normal mice mitigates intestinal barrier injury and gut dysbiosis induced by antibiotics and cyclophosphamide","volume":"14","author":"Huang","year":"2023","journal-title":"Food Funct"},{"issue":"10","key":"10.1016\/j.aninu.2024.06.004_bib20","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1023\/A:1026647024077","article-title":"Probiotic bacteria stimulate gut epithelial cell proliferation in rat","volume":"44","author":"Ichikawa","year":"1999","journal-title":"Dig Dis Sci"},{"issue":"7","key":"10.1016\/j.aninu.2024.06.004_bib21","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1093\/molbev\/msw054","article-title":"MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets","volume":"33","author":"Kumar","year":"2016","journal-title":"Mol Biol Evol"},{"issue":"7","key":"10.1016\/j.aninu.2024.06.004_bib22","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.3390\/antiox12071342","article-title":"Exploring the benefits of probiotics in gut inflammation and diarrhea - from an antioxidant perspective","volume":"12","author":"Li","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.aninu.2024.06.004_bib23","article-title":"Sodium butyrate ameliorates oxidative stress-induced intestinal epithelium barrier injury and mitochondrial damage through AMPK-mitophagy pathway","volume":"2022","author":"Li","year":"2022","journal-title":"Oxid Med Cell Longev"},{"key":"10.1016\/j.aninu.2024.06.004_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2021.763700","article-title":"Effects of dietary supplementation with Clostridium butyricum on the amelioration of growth performance, rumen fermentation, and rumen microbiota of holstein heifers","volume":"8","author":"Li","year":"2021","journal-title":"Front Nutr"},{"issue":"1","key":"10.1016\/j.aninu.2024.06.004_bib25","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1186\/s12866-023-02896-9","article-title":"Diarrhea accompanies intestinal inflammation and intestinal mucosal microbiota dysbiosis during fatigue combined with a high-fat diet","volume":"23","author":"Liu","year":"2023","journal-title":"BMC Microbiol"},{"issue":"2","key":"10.1016\/j.aninu.2024.06.004_bib26","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1093\/jas\/sky459","article-title":"Infusion of sodium butyrate promotes rumen papillae growth and enhances expression of genes related to rumen epithelial VFA uptake and metabolism in neonatal twin lambs","volume":"97","author":"Liu","year":"2019","journal-title":"J\u00a0Anim Sci"},{"issue":"8","key":"10.1016\/j.aninu.2024.06.004_bib27","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1136\/gutjnl-2013-304833","article-title":"A\u00a0decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis","volume":"63","author":"Machiels","year":"2014","journal-title":"Gut"},{"issue":"10","key":"10.1016\/j.aninu.2024.06.004_bib28","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.3390\/ijms17101696","article-title":"Sodium butyrate promotes reassembly of tight junctions in caco-2 monolayers involving inhibition of MLCK\/MLC2 pathway and phosphorylation of PKCbeta2","volume":"17","author":"Miao","year":"2016","journal-title":"Int J Mol Sci"},{"issue":"2","key":"10.1016\/j.aninu.2024.06.004_bib29","doi-asserted-by":"crossref","first-page":"e00300","DOI":"10.1128\/mBio.00300-15","article-title":"Identification of metabolic signatures linked to anti-inflammatory effects of Faecalibacterium prausnitzii","volume":"6","author":"Miquel","year":"2015","journal-title":"mBio"},{"issue":"1","key":"10.1016\/j.aninu.2024.06.004_bib30","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/j.1536-4801.1991.tb10178.x","article-title":"Pathophysiology of infectious diarrhea: changes in intestinal structure and function","volume":"12","author":"O'Loughlin","year":"1991","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"issue":"6","key":"10.1016\/j.aninu.2024.06.004_bib31","first-page":"2627","article-title":"Probiotic supplementation protects weaned pigs against enterotoxigenic Escherichia coli K88 challenge and improves performance similar to antibiotics","volume":"95","author":"Pan","year":"2017","journal-title":"J\u00a0Anim Sci"},{"issue":"11","key":"10.1016\/j.aninu.2024.06.004_bib32","doi-asserted-by":"crossref","first-page":"3839","DOI":"10.3390\/nu13113839","article-title":"Intestinal microbiota as a contributor to chronic inflammation and its potential modifications","volume":"13","author":"Potrykus","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.aninu.2024.06.004_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2019.05.005","article-title":"Induction effects of Faecalibacterium prausnitzii and its extracellular vesicles on toll-like receptor signaling pathway gene expression and cytokine level in human intestinal epithelial cells","volume":"121","author":"Rabiei","year":"2019","journal-title":"Cytokine"},{"key":"10.1016\/j.aninu.2024.06.004_bib34","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.2584","article-title":"VSEARCH: a versatile open source tool for metagenomics","volume":"4","author":"Rognes","year":"2016","journal-title":"PeerJ"},{"key":"10.1016\/j.aninu.2024.06.004_bib35","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3389\/fmicb.2017.00095","article-title":"Trophic interactions of infant bifidobacteria and Eubacterium hallii during L-fucose and fucosyllactose degradation","volume":"8","author":"Schwab","year":"2017","journal-title":"Front Microbiol"},{"issue":"Suppl 1","key":"10.1016\/j.aninu.2024.06.004_bib36","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.33549\/physiolres.933414","article-title":"Preventive and therapeutic application of molecular hydrogen in situations with excessive production of free radicals","volume":"65","author":"Slezak","year":"2016","journal-title":"Physiol Res"},{"issue":"2","key":"10.1016\/j.aninu.2024.06.004_bib37","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/MOG.0000000000000902","article-title":"Probiotics in irritable bowel syndrome and inflammatory bowel disease: review of mechanisms and effectiveness","volume":"39","author":"So","year":"2023","journal-title":"Curr Opin Gastroenterol"},{"issue":"43","key":"10.1016\/j.aninu.2024.06.004_bib38","doi-asserted-by":"crossref","first-page":"16731","DOI":"10.1073\/pnas.0804812105","article-title":"Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients","volume":"105","author":"Sokol","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"10.1016\/j.aninu.2024.06.004_bib39","first-page":"670","article-title":"Characterization of intestinal microbiota in lambs with different susceptibility to Escherichia coli F17","volume":"9","author":"Sun","year":"2022","journal-title":"Vet Sci"},{"issue":"2","key":"10.1016\/j.aninu.2024.06.004_bib40","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.aninu.2020.08.012","article-title":"Dietary inclusion of multispecies probiotics to reduce the severity of post-weaning diarrhea caused by Escherichia coli F18(+) in pigs","volume":"7","author":"Sun","year":"2021","journal-title":"Anim Nutr"},{"issue":"1","key":"10.1016\/j.aninu.2024.06.004_bib41","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/s40168-022-01389-7","article-title":"Colonocyte-derived lactate promotes E. coli fitness in the context of inflammation-associated gut microbiota dysbiosis","volume":"10","author":"Taylor","year":"2022","journal-title":"Microbiome"},{"key":"10.1016\/j.aninu.2024.06.004_bib42","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.ijbiomac.2016.03.010","article-title":"Different effects of lipoteichoic acid from C. butyricum and S. aureus on inflammatory responses of HT-29 cells","volume":"87","author":"Wang","year":"2016","journal-title":"Int J Biol Macromol"},{"issue":"10","key":"10.1016\/j.aninu.2024.06.004_bib43","doi-asserted-by":"crossref","first-page":"4140","DOI":"10.1093\/jas\/skz235","article-title":"Effects of Clostridium butyricum and Enterococcus faecalis on growth performance, intestinal structure, and inflammation in lipopolysaccharide-challenged weaned piglets","volume":"97","author":"Wang","year":"2019","journal-title":"J\u00a0Anim Sci"},{"issue":"10","key":"10.1016\/j.aninu.2024.06.004_bib44","doi-asserted-by":"crossref","first-page":"825","DOI":"10.3390\/ani9100825","article-title":"Effect of age and weaning on growth performance, rumen fermentation, and serum parameters in lambs fed starter with limited Ewe - lamb interaction","volume":"9","author":"Wang","year":"2019","journal-title":"Animals"},{"issue":"14","key":"10.1016\/j.aninu.2024.06.004_bib45","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241411423","article-title":"Combining 16S rRNA sequencing and metabolomics data to decipher the interactions between gut microbiota, host immunity, and metabolites in diarrheic young small ruminants","volume":"24","author":"Wang","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"5","key":"10.1016\/j.aninu.2024.06.004_bib46","doi-asserted-by":"crossref","first-page":"775","DOI":"10.3920\/BM2017.0035","article-title":"Lactobacillus acidophilus and Clostridium butyricum ameliorate colitis in murine by strengthening the gut barrier function and decreasing inflammatory factors","volume":"9","author":"Wang","year":"2018","journal-title":"Benef Microbes"},{"issue":"4","key":"10.1016\/j.aninu.2024.06.004_bib47","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.aninu.2020.05.008","article-title":"Effects of dietary energy on growth performance, carcass characteristics, serum biochemical index, and meat quality of female Hu lambs","volume":"6","author":"Wang","year":"2020","journal-title":"Anim Nutr"},{"issue":"8","key":"10.1016\/j.aninu.2024.06.004_bib48","doi-asserted-by":"crossref","DOI":"10.1093\/jas\/skac205","article-title":"Effect of feeding calcium gluconate embedded in a hydrogenated fat matrix on feed intake, gastrointestinal fermentation and morphology, intestinal brush border enzyme activity and blood metabolites in growing lambs","volume":"100","author":"Watanabe","year":"2022","journal-title":"J\u00a0Anim Sci"},{"issue":"Pt B","key":"10.1016\/j.aninu.2024.06.004_bib49","article-title":"Clostridium butyricum alleviates weaned stress of piglets by improving intestinal immune function and gut microbiota","volume":"405","author":"Wu","year":"2023","journal-title":"Food Chem"},{"key":"10.1016\/j.aninu.2024.06.004_bib50","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.nut.2018.06.007","article-title":"Vitamin A supplementation improves the intestinal mucosal barrier and facilitates the expression of tight junction proteins in rats with diarrhea","volume":"57","author":"Xiao","year":"2019","journal-title":"Nutrition"},{"issue":"7","key":"10.1016\/j.aninu.2024.06.004_bib51","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1093\/ecco-jcc\/jjab003","article-title":"Modulation of the gut microbiota-farnesoid X receptor Axis improves deoxycholic acid-induced intestinal inflammation in mice","volume":"15","author":"Xu","year":"2021","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1016\/j.aninu.2024.06.004_bib52","article-title":"Clostridium butyricum alleviates LPS-induced acute immune stress in goats by regulating bacterial communities and blood metabolites","volume":"14","author":"Zhang","year":"2023","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.aninu.2024.06.004_bib53","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1093\/bioinformatics\/btt593","article-title":"PEAR: a fast and accurate Illumina Paired-End reAd mergeR","volume":"30","author":"Zhang","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.aninu.2024.06.004_bib54","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13099-017-0160-6","article-title":"Oral administration of Clostridium butyricum CGMCC0313-1 inhibits beta-lactoglobulin-induced intestinal anaphylaxis in a mouse model of food allergy","volume":"9","author":"Zhang","year":"2017","journal-title":"Gut Pathog"},{"issue":"18","key":"10.1016\/j.aninu.2024.06.004_bib55","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.3390\/ani12182332","article-title":"Physiological, immune response, antioxidant capacity and lipid metabolism changes in grazing sheep during the cold season","volume":"12","author":"Zhang","year":"2022","journal-title":"Animals"},{"key":"10.1016\/j.aninu.2024.06.004_bib56","first-page":"2385","article-title":"Prediction and equation of effective energy values of common roughages for mutton sheep","volume":"28","author":"Zhao","year":"2016","journal-title":"Chin. J. Anim. Nutr."},{"key":"10.1016\/j.aninu.2024.06.004_bib57","doi-asserted-by":"crossref","first-page":"299","DOI":"10.3389\/fmicb.2020.00299","article-title":"Clostridium butyricum ameliorates Salmonella enteritis induced inflammation by enhancing and improving immunity of the intestinal epithelial barrier at the intestinal mucosal level","volume":"11","author":"Zhao","year":"2020","journal-title":"Front Microbiol"},{"issue":"12","key":"10.1016\/j.aninu.2024.06.004_bib58","doi-asserted-by":"crossref","first-page":"8502","DOI":"10.3390\/ijms12128502","article-title":"Effects of soybean agglutinin on intestinal barrier permeability and tight junction protein expression in weaned piglets","volume":"12","author":"Zhao","year":"2011","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.aninu.2024.06.004_bib59","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.livsci.2018.12.024","article-title":"Effects of Clostridium butyricum or in combination with Bacillus licheniformis on the growth performance, blood indexes, and intestinal barrier function of weanling piglets","volume":"220","author":"Zong","year":"2019","journal-title":"Livest Sci"}],"container-title":["Animal Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405654524000933?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405654524000933?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T17:35:22Z","timestamp":1762623322000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405654524000933"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":59,"alternative-id":["S2405654524000933"],"URL":"https:\/\/doi.org\/10.1016\/j.aninu.2024.06.004","relation":{},"ISSN":["2405-6545"],"issn-type":[{"value":"2405-6545","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sheep-derived butyrate-producing Clostridium beijerinckii R8 alleviates diarrhea by shaping the gut microbiota of goat kids","name":"articletitle","label":"Article Title"},{"value":"Animal Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aninu.2024.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd\u00e9","name":"copyright","label":"Copyright"}]}}