{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T22:20:34Z","timestamp":1782858034746,"version":"3.54.5"},"reference-count":37,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Animal Reproduction Science"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1016\/j.anireprosci.2010.10.014","type":"journal-article","created":{"date-parts":[[2010,11,5]],"date-time":"2010-11-05T04:27:44Z","timestamp":1288931264000},"page":"106-111","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Cholesterol-loaded cyclodextrin inhibits premature acrosomal reactions in liquid-stored rabbit spermatozoa"],"prefix":"10.1016","volume":"123","author":[{"given":"\u0130lker","family":"Serin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melih","family":"Aksoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Ceylan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anireprosci.2010.10.014_bib0005","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.anireprosci.2010.02.014","article-title":"Cholesterol-loaded cyclodextrin enhances osmotic tolerance and inhibits the acrosome reaction in rabbit spermatozoa","volume":"120","author":"Aksoy","year":"2010","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/j.1939-4640.2000.tb03268.x","article-title":"Semen cryopreservation in domestic animals: a damaging and capacitating phenomenon","volume":"21","author":"Bailey","year":"2000","journal-title":"J. Androl."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0015","first-page":"597","article-title":"Sperm capacitation","volume":"Vol. 4","author":"Bedford","year":"1998"},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0020","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1530\/jrf.0.0910403","article-title":"Epididymal storage at abdominal temperature reduces the time required for capacitation of hamster spermatozoa","volume":"91","author":"Bedford","year":"1991","journal-title":"J. Reprod. Fert."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0025","series-title":"Proc. 9th World Rabbit Congress","first-page":"81","article-title":"Semen production and management of rabbit bucks","author":"Castellini","year":"2008"},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0030","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.theriogenology.2005.05.053","article-title":"Lipid composition of the main fractions of rabbit semen","volume":"65","author":"Castellini","year":"2006","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0035","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1002\/j.1939-4640.1997.tb01953.x","article-title":"Premature capacitation of bovine spermatozoa is initiated by cryopreservation","volume":"18","author":"Cormier","year":"1997","journal-title":"J. Androl."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0040","first-page":"19","article-title":"Effect of cholesterol and other sterols on human sperm acrosomal responsiveness","volume":"55","author":"Cross","year":"1996","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0045","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1530\/ror.0.0020048","article-title":"Reactive oxygen species and sperm physiology","volume":"2","author":"De Lamirande","year":"1997","journal-title":"Rev. Reprod."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0050","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1089\/cpt.2005.3.165","article-title":"The effect of blueberry extracts and quercetin on capacitation status of stored boar sperm","volume":"3","author":"Desroches","year":"2005","journal-title":"Cell Preserv. Technol."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0055","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1530\/jrf.0.0140393","article-title":"Properties of decapacitation factor and presence in various species","volume":"14","author":"Dukelow","year":"1967","journal-title":"J. Reprod. Fert."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0060","series-title":"Salamon's Artificial Insemination of Sheep and Goats","first-page":"93","article-title":"Handling and examination of semen","author":"Evans","year":"1987"},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0065","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0012-1606(82)90015-X","article-title":"Mouse gamete interactions, the zona pellucida is the site of the acrosome reaction leading to fertilization in vitro","volume":"91","author":"Florman","year":"1982","journal-title":"Dev. Biol."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0070","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1002\/jez.1402330309","article-title":"Effects of temperature upon capacitation of guinea pig spermatozoa","volume":"233","author":"Fleming","year":"1985","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0075","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1095\/biolreprod32.1.145","article-title":"Albumin-mediated changes in sperm sterol content during capacitation","volume":"32","author":"Go","year":"1985","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0080","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1002\/j.1939-4640.1997.tb01925.x","article-title":"Objectively measured boar sperm motility parameters correlate with the outcomes of on-farm inseminations: results of two fertility trials","volume":"18","author":"Holt","year":"1997","journal-title":"J. Androl."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0085","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/j.1939-4640.2000.tb02124.x","article-title":"Cholesterol inhibitory effects on human sperm-induced acrosome reaction","volume":"21","author":"Khorasani","year":"2000","journal-title":"J. Androl."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0090","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/j.1939-4640.2002.tb02232.x","article-title":"Zona pellucida and progesterone-induced Ca2+ signaling and acrosome reaction in human spermatozoa","volume":"23","author":"Kirkman-Brown","year":"2002","journal-title":"J. Androl."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0095","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/humrep\/13.3.611","article-title":"Factors influencing human sperm kinematic measurements by the Celltrak computer-assisted sperm analysis system","volume":"13","author":"Kraemer","year":"1998","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0100","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1262\/jrd.19031","article-title":"Premature capacitation of frozen-thawed spermatozoa from subfertile Japanese Black cattle","volume":"53","author":"Kuroda","year":"2007","journal-title":"J. Reprod. Dev."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0105","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/(SICI)1098-2795(199904)52:4<445::AID-MRD14>3.0.CO;2-6","article-title":"Simple histochemical stain for acrosomes on sperm from several species","volume":"52","author":"Larson","year":"1999","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0110","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1530\/jrf.0.0350055","article-title":"The effects of temperature, osmolality and hydrogen ion concentration on the activation and acrosome reaction of golden hamster spermatozoa","volume":"35","author":"Mahi","year":"1973","journal-title":"J. Reprod. Fert."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0115","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/S0093-691X(99)00222-8","article-title":"Physiology of spermatozoa at high dilution rates: the influence of seminal plasma","volume":"52","author":"Maxwell","year":"1999","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0120","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1089\/cpt.2006.4.169","article-title":"Effect of quercetin on capacitation status and lipid peroxidation of stallione spermatozoa","volume":"4","author":"McNiven","year":"2006","journal-title":"Cell Preserv. Technol."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10344-008-0207-6","article-title":"Capacitation status of frozen-thawed spermatozoa from wild ruminant species","volume":"55","author":"Mejia","year":"2009","journal-title":"Eur. J. Wildl. Res."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0130","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1262\/jrd.19026","article-title":"Seasonal changes in semen characteristics, composition of seminal plasma and frequency of acrosome reaction induced by calcium and calcium ionophore A23187 in large white boars","volume":"53","author":"Murase","year":"2007","journal-title":"J. Reprod. Dev."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0135","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1095\/biolreprod.103.025577","article-title":"Effect of adding cholesterol to sperm membranes on sperm capacitation, the acrosome reaction, and fertility","volume":"71","author":"Purdy","year":"2004","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0140","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.cryobiol.2003.12.001","article-title":"Effect of cholesterol-loaded cyclodextrin on the cryosurvival of bull sperm","volume":"48","author":"Purdy","year":"2004","journal-title":"Cryobiology"},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0145","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0378-4320(00)00185-8","article-title":"Viability and fertility of rabbit spermatozoa diluted in tris-buffer extenders and stored at 15\u00b0C","volume":"64","author":"Roca","year":"2000","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0150","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.anireprosci.2009.08.001","article-title":"Cholesterol-loaded-cyclodextrins and fertility potential of stallions spermatozoa","volume":"118","author":"Spizziri","year":"2010","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0155","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1046\/j.1439-0272.2003.00564.x","article-title":"Reactive oxygen species induce reversible capacitation in human spermatozoa","volume":"35","author":"Villegas","year":"2003","journal-title":"Andrologia"},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0160","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1002\/j.1939-4640.1998.tb01994.x","article-title":"The molecular basis of sperm capacitation","volume":"19","author":"Visconti","year":"1998","journal-title":"J. Androl."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0165","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1002\/jcp.20389","article-title":"Contribution of mouse egg zona pellucida glycoproteins to gamete recognition during fertilization","volume":"204","author":"Wassarman","year":"2005","journal-title":"J. Cell Physiol."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0170","series-title":"Effects of Low Temperatures on Biological Membranes","first-page":"189","article-title":"The effects of cold shock on sperm cell membranes","author":"Watson","year":"1981"},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0175","series-title":"The Physiology of Reproduction","first-page":"189","article-title":"Mammalian fertilization","author":"Yanagimachi","year":"1994"},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0180","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1095\/biolreprod55.1.19","article-title":"The unesterified cholesterol content of human sperm regulates response of the acrosome to the agonist, progesterone","volume":"55","author":"Zarintash","year":"1996","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.anireprosci.2010.10.014_bib0185","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1016\/S0093-691X(00)00290-9","article-title":"Evaluation on sperm quality of freshly ejaculated boar semen during in vitro storage under different temperatures","volume":"53","author":"Zou","year":"2000","journal-title":"Theriogenology"}],"container-title":["Animal Reproduction Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432010004495?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432010004495?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T06:17:14Z","timestamp":1759904234000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378432010004495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":37,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["S0378432010004495"],"URL":"https:\/\/doi.org\/10.1016\/j.anireprosci.2010.10.014","relation":{},"ISSN":["0378-4320"],"issn-type":[{"value":"0378-4320","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cholesterol-loaded cyclodextrin inhibits premature acrosomal reactions in liquid-stored rabbit spermatozoa","name":"articletitle","label":"Article Title"},{"value":"Animal Reproduction Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anireprosci.2010.10.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}