{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:54:47Z","timestamp":1790639687377,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Animal Reproduction Science"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.anireprosci.2015.06.016","type":"journal-article","created":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T17:53:14Z","timestamp":1435168394000},"page":"184-190","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["The effect of short fasting on the hypothalamic neuronal system of kisspeptin in peripubertal female lambs"],"prefix":"10.1016","volume":"159","author":[{"given":"Jolanta","family":"Polkowska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6160-3775","authenticated-orcid":false,"given":"Magdalena","family":"Cie\u015blak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Wa\u0144kowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"W\u00f3jcik-G\u0142adysz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anireprosci.2015.06.016_bib0005","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1210\/en.2009-1190","article-title":"Kisspeptin cells in the ewe brain respond to leptin and communicate with neuropeptide Y and proopiomelanocortin cells","volume":"151","author":"Backholer","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0010","doi-asserted-by":"crossref","first-page":"5258","DOI":"10.1210\/en.2007-0554","article-title":"Kisspeptin synchronized preovulatory surges in cyclical ewes and causes ovulation in seasonally acyclic ewes","volume":"148","author":"Caraty","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0015","doi-asserted-by":"crossref","first-page":"3917","DOI":"10.1210\/en.2005-0337","article-title":"Changes in hypothalamic KiSS-1 system and restoration of pubertal activation on the reproductive axis by kisspeptin in undernutrition","volume":"146","author":"Castellano","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0020","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1095\/biolreprod60.2.216","article-title":"Leptin's action on reproductive axis; perspectives and mechanisms","volume":"60","author":"Cunningham","year":"1999","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0025","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.neulet.2006.03.039","article-title":"Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha","volume":"401","author":"Francheschini","year":"2006","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0030","doi-asserted-by":"crossref","first-page":"5105","DOI":"10.1210\/en.2012-1550","article-title":"Kisspeptin neurons from mice to men: similarities and differences","volume":"153","author":"Goodman","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0035","doi-asserted-by":"crossref","first-page":"5752","DOI":"10.1210\/en.2007-0961","article-title":"Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B","volume":"148","author":"Goodman","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0040","doi-asserted-by":"crossref","first-page":"4073","DOI":"10.1210\/en.2004-0431","article-title":"A role for kisspetins in the regulation of gonadotropin secretion in the mouse","volume":"145","author":"Gottsch","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0045","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1210\/en.2010-0066","article-title":"Expression of fos and in vivo median eminence release of LHRH identifies an active role for preoptic area kisspeptin neurons in synchronized surges of LH and LHRH in the ewe","volume":"152","author":"Hoffman","year":"2011","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0050","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1095\/biolreprod37.4.755","article-title":"Changes in episodic luteinizing hormone secretion leading to puberty in the lamb","volume":"37","author":"Huffman","year":"1987","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0055","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1210\/endo.141.2.7308","article-title":"Central inhibition of gonadotropin-releasing hormone secretion in the growth-restricted hypogonadotropic female sheep","volume":"141","author":"I\u2019Anson","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0060","first-page":"246","article-title":"Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat","volume":"80","author":"Irving","year":"2004","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0065","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1677\/JOE-10-0129","article-title":"Sensitivities of mRNA status are changed during the developmental period in female rats","volume":"207","author":"Iwasa","year":"2010","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0070","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1111\/j.1365-2826.2008.01757.x","article-title":"Fasting reduces KiSS-1 expression in the anteroventral periventricular nucleus (AVPV): Effects of fasting on the expression of KiSS-1 and neuropeptide Y in the AVPV or arcuate nucleus of female rats","volume":"20","author":"Kalamatianos","year":"2008","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0075","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1210\/endo-128-2-843","article-title":"Gonadotropin releasing hormone overrides the negative effect of reduced dietary energy on gonadotropin synthesis and secretion in ewes","volume":"128","author":"Kile","year":"1991","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0080","doi-asserted-by":"crossref","first-page":"4601","DOI":"10.1210\/en.2007-0500","article-title":"Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using models and cell line","volume":"148","author":"Lugue","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0085","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1507\/endocrj.K11E-131","article-title":"Fasting reduces the kiss1 mRNA levels in the caudal hypothalamus of gonadally intact female rats","volume":"58","author":"Matsuzaki","year":"2011","journal-title":"Endocrine J."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0090","doi-asserted-by":"crossref","first-page":"5406","DOI":"10.1210\/en.2012-1357","article-title":"KNDy (kisspeptin\/neurokinin B\/dynorphin) neurons are activated during both pulsatile and surge secretion of LH in the ewe","volume":"153","author":"Merkley","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0095","first-page":"E310","article-title":"Algorithms for the study of episodic hormone secretion","volume":"243","author":"Merriam","year":"1989","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0100","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/1043-2760(94)P3204-K","article-title":"Gonadal steroid hormone regulation of the somatotrophic axis during puberty of humans","volume":"5","author":"Metzenger","year":"1994","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0105","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.peptides.2008.09.004","article-title":"The neuroanatomy of the kisspeptin system in the mammalian brain","volume":"30","author":"Mikkelsen","year":"2009","journal-title":"Peptides"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0110","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1210\/en.2011-2009","article-title":"Evidence of a role for kisspeptin and neurokinin B in puberty of female sheep","volume":"153","author":"Nestor","year":"2009","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0115","doi-asserted-by":"crossref","first-page":"139","DOI":"10.22358\/jafs\/65702\/2014","article-title":"Localization of kisspeptin neurons in the hypothalamus of peripubertal female lambs; possible connection with gonadotrophin releasing hormone and neuropeptide Y neurons","volume":"23","author":"Polkowska","year":"2014","journal-title":"J. Anim. Feed Sci."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0120","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0378-4320(02)00237-3","article-title":"Effect of dietary protein on the secretion of luteinizing hormone and follicle-stimulating hormone in pre-pubertal female lambs","volume":"76","author":"Polkowska","year":"2003","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0125","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jchemneu.2006.05.001","article-title":"The effect of intracerebroventricular infusions of leptin on the immunoreactivity of neuropeptide Y and gonadotrophin releasing hormone neurons in the hypothalamus of prepubertal sheep in conditions of short fasting","volume":"32","author":"Polkowska","year":"2006","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0130","doi-asserted-by":"crossref","first-page":"4387","DOI":"10.1210\/en.2008-0438","article-title":"Structural interactions between kisspeptin and GnRH neurons in the medial-basal hypothalamus of the male rhesus monkey (Macaca mulatta) as revealed by double immunofluorescence and confocal microscopy","volume":"149","author":"Ramaswamy","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0135","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1111\/j.1365-2826.2011.02177.x","article-title":"Developmental changes in hypothalamic KiSS1 expression during activation of the pulsatile release of luteinizing hormone in maturing ewe lambs","volume":"23","author":"Redmond","year":"2011","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0140","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1095\/biolreprod45.3.471","article-title":"Patterns of circulating gonadotropins and ovarian steroids during the first periovulatory period in the developing sheep","volume":"45","author":"Ryan","year":"1991","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0145","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.physbeh.2004.02.007","article-title":"Energy balance and reproduction","volume":"81","author":"Schneider","year":"2004","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0150","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1073\/pnas.0409822102","article-title":"Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates","volume":"102","author":"Shahab","year":"2005","journal-title":"PNAS"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0155","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/j.1365-2826.2006.01417.x","article-title":"KiSS-1 neurones are direct targets for leptin in the ob\/ob mouse","volume":"18","author":"Smith","year":"2006","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0160","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1530\/rep.1.00368","article-title":"Regulation of the neuroendocrine reproductive axis by kisspeptin-GPR 54 signaling","volume":"131","author":"Smith","year":"2006","journal-title":"Reproduction"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0165","doi-asserted-by":"crossref","first-page":"5530","DOI":"10.1210\/en.2009-0712","article-title":"Kisspeptin neurons in the ovine arcuate nucleus and preoptic area are involved in the preovulatory luteinizing hormone surge","volume":"150","author":"Smith","year":"2009","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0170","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1210\/en.2010-1225","article-title":"Kisspeptin is essential for the full preovulatory LH surge and stimulates GnRH release from the isolated ovine median eminence","volume":"152","author":"Smith","year":"2011","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0175","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1095\/biolreprod.110.085407","article-title":"Hypothalamic expression of KISS1 and gonadotropin inhibitory hormone genes during the menstrual cycle of a non-human primate","volume":"83","author":"Smith","year":"2010","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0180","first-page":"1","article-title":"Direct radioimmunoassay of progesterone in human plasma","volume":"80","author":"Stupnicki","year":"1982","journal-title":"Endokrinologie"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0185","first-page":"6","article-title":"Radioimmunoassay of LH in the blood plasma of farm animals","volume":"68","author":"Stupnicki","year":"1976","journal-title":"Endokrinologie"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0190","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1210\/endo-126-3-1361","volume":"126","author":"Thomas","year":"1990","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0195","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1365-2826.2009.01853.x","article-title":"Kisspeptin\/metastin: a key molecule controlling two modes of gonadotrophin-releasing hormone\/luteinising hormone release in female rats","volume":"21","author":"Uenoyama","year":"2009","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0200","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jchemneu.2009.05.003","article-title":"Gonadotrophin-releasing hormone and GnRH-associated peptide neurobiology from the rearing period until puberty in the female sheep","volume":"38","author":"Wa\u0144kowska","year":"2009","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0205","first-page":"1","article-title":"Observations on the streotaxic configuration of the hypothalamus nuclei in the sheep","volume":"124","author":"Welento","year":"1969","journal-title":"Anat. Anz."},{"key":"10.1016\/j.anireprosci.2015.06.016_bib0210","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.anireprosci.2008.10.009","article-title":"Effect of intracerebroventricular infusion of leptin on the secretory activity of the GnRH\/LH axis in fasted prepubertal lambs","volume":"114","author":"W\u00f3jcik-G\u0142adysz","year":"2009","journal-title":"Anim. Reprod. Sci."}],"container-title":["Animal Reproduction Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432015001475?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432015001475?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T06:29:53Z","timestamp":1759904993000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378432015001475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":42,"alternative-id":["S0378432015001475"],"URL":"https:\/\/doi.org\/10.1016\/j.anireprosci.2015.06.016","relation":{},"ISSN":["0378-4320"],"issn-type":[{"value":"0378-4320","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of short fasting on the hypothalamic neuronal system of kisspeptin in peripubertal female lambs","name":"articletitle","label":"Article Title"},{"value":"Animal Reproduction Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anireprosci.2015.06.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}