{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:34:07Z","timestamp":1786984447937,"version":"build-2736575974"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Animal Reproduction Science"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.anireprosci.2021.106837","type":"journal-article","created":{"date-parts":[[2021,9,3]],"date-time":"2021-09-03T11:19:05Z","timestamp":1630667945000},"page":"106837","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["MicroRNAs are potential regulators of the timed artificial insemination effect in gilt endometrium"],"prefix":"10.1016","volume":"233","author":[{"given":"Zhao","family":"Qianqian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"Chuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cui","family":"Zhenliang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Qiaoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"Mingzhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Longyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bai","family":"Rui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Jianhui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Junjie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weng","family":"Shiqiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anireprosci.2021.106837_bib1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","article-title":"MicroRNAs: genomics, biogenesis, mechanism, and function","volume":"116","author":"Bartel","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.anireprosci.2021.106837_bib2","first-page":"1","article-title":"Ultrafast and memory-efficient alignment of short DNA sequences to the human genome","volume":"10","author":"Ben","year":"2009","journal-title":"Genome Biol."},{"key":"10.1016\/j.anireprosci.2021.106837_bib3","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/S0093-691X(96)00258-0","article-title":"Control of ovulation with a GnRH analog in gilts and sows","volume":"46","author":"Br\u00fcssow","year":"1996","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2021.106837_bib4","doi-asserted-by":"crossref","first-page":"533","DOI":"10.2298\/BAH1103533B","article-title":"Biological and technological background of estrus synchronization and fixed-time ovulation induction in the pig","volume":"27","author":"Br\u00fcssow","year":"2011","journal-title":"Biotechnol. Anim. Husb."},{"key":"10.1016\/j.anireprosci.2021.106837_bib5","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1084\/jem.20180639","article-title":"Gain-of-function IKBKB mutation causes human combined immune deficiency","volume":"215","author":"Cardinez","year":"2018","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.anireprosci.2021.106837_bib6","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/j.theriogenology.2016.04.089","article-title":"Control of estrus and ovulation: fertility to timed insemination of gilts and sows","volume":"86","author":"De Rensis","year":"2016","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2021.106837_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/gb-2003-4-9-r60","article-title":"DAVID: database for annotation, visualization, and integrated discovery","volume":"4","author":"Dennis","year":"2003","journal-title":"Genome Biol."},{"key":"10.1016\/j.anireprosci.2021.106837_bib8","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.anireprosci.2013.12.003","article-title":"Fixed-time post-cervical artificial insemination in sows receiving porcine luteinising hormone at oestrus onset","volume":"144","author":"Fontana","year":"2014","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.anireprosci.2021.106837_bib9","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1093\/nar\/gkr688","article-title":"miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades","volume":"40","author":"Friedlnder","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.anireprosci.2021.106837_bib10","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1091\/mbc.E14-07-1247","article-title":"The formin FMNL3 assembles plasma membrane protrusions that participate in cell\u2013cell adhesion","volume":"26","author":"Gauvin","year":"2015","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.anireprosci.2021.106837_bib11","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3389\/fgene.2019.00661","article-title":"Differential microRNA expression in porcine endometrium involved in remodeling and angiogenesis that contributes to embryonic implantation","volume":"10","author":"Hong","year":"2019","journal-title":"Front. Genet."},{"key":"10.1016\/j.anireprosci.2021.106837_bib12","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1523\/JNEUROSCI.1634-18.2018","article-title":"Drebrin-like (Dbnl) controls neuronal migration via regulating N-cadherin expression in the developing cerebral cortex","volume":"39","author":"Inoue","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/j.anireprosci.2021.106837_bib13","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1126\/science.1085242","article-title":"Role of microRNAs in plant and animal development","volume":"301","author":"Jc","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.anireprosci.2021.106837_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2049-1891-6-3","article-title":"Current strategies for reproductive management of gilts and sows in North America","volume":"6","author":"Kraeling","year":"2015","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.anireprosci.2021.106837_bib15","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jaci.2013.12.1083","article-title":"The BLNK adaptor protein has a nonredundant role in human B-cell differentiation","volume":"134","author":"Lagreslepeyrou","year":"2014","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.anireprosci.2021.106837_bib16","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1111\/j.1582-4934.2008.00513.x","article-title":"MicroRNAs in embryonic stem cells and early embryonic development","volume":"12","author":"Laurent","year":"2010","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.anireprosci.2021.106837_bib17","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212 \u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.anireprosci.2021.106837_bib18","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/cm.20167","article-title":"Shroom4 (Kiaa1202) is an actin-associated protein implicated in cytoskeletal organization","volume":"64","author":"Michael","year":"2007","journal-title":"Cell Motil. Cytoskelet."},{"key":"10.1016\/j.anireprosci.2021.106837_bib19","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1038\/nature08889","article-title":"MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis","volume":"464","author":"Nicoli","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.anireprosci.2021.106837_bib20","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nrc3204","article-title":"The diverse and complex roles of NF-\u03baB subunits in cancer","volume":"12","author":"Perkins","year":"2012","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.anireprosci.2021.106837_bib21","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.fertnstert.2012.11.001","article-title":"MicroRNA expression in the human blastocyst","volume":"99","author":"Rosenbluth","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.anireprosci.2021.106837_bib22","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.theriogenology.2017.12.051","article-title":"Additional small dose of prostaglandin F2\u03b1 at timed artificial insemination failed to improve pregnancy risk of lactating dairy cows","volume":"110","author":"Sauls","year":"2018","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2021.106837_bib23","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1083\/jcb.201204010","article-title":"Structural insights into WHAMM-mediated cytoskeletal coordination during membrane remodeling","volume":"199","author":"Shen","year":"2012","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.anireprosci.2021.106837_bib24","doi-asserted-by":"crossref","first-page":"29","DOI":"10.15252\/embr.201744371","article-title":"ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton","volume":"19","author":"Song","year":"2018","journal-title":"EMBO Rep."},{"key":"10.1016\/j.anireprosci.2021.106837_bib25","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/nsmb.2462","article-title":"FMNL3 FH2\/actin strucutre gives insight into formin-mediated actin nucleation and elongation","volume":"20","author":"Thompson","year":"2013","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.anireprosci.2021.106837_bib26","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1111\/rda.12362","article-title":"Use of porcine luteinizing hormone at oestrous onset in a protocol for fixed\u2010time artificial insemination in gilts","volume":"49","author":"Ulguim","year":"2014","journal-title":"Reprod. Dom. Anim."},{"key":"10.1016\/j.anireprosci.2021.106837_bib27","first-page":"1","article-title":"Effect of fixed-time artificial insemination on corpus luteum gene expression at the day 16 and 25 pregnancy of gilt","author":"Wei","year":"2021","journal-title":"Anim. Biotechnol."},{"key":"10.1016\/j.anireprosci.2021.106837_bib28","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1262\/jrd.2015-064","article-title":"Characterization and comparative analyses of transcriptomes for in vivo and in vitro produced peri-implantation conceptuses and endometria from sheep","volume":"62","author":"Wei","year":"2016","journal-title":"J. Reprod. Dev."},{"key":"10.1016\/j.anireprosci.2021.106837_bib29","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/1471-2105-13-140","article-title":"miREvo: an integrative microRNA evolutionary analysis platform for next-generation sequencing experiments","volume":"13","author":"Wen","year":"2012","journal-title":"BMC Bioinform."},{"key":"10.1016\/j.anireprosci.2021.106837_bib30","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1093\/nar\/gks554","article-title":"PsRobot: a web-based plant small RNA meta-analysis toolbox","volume":"40","author":"Wu","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.anireprosci.2021.106837_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13046-018-0958-1","article-title":"Hypermethylation of DMTN promotes the metastasis of colorectal cancer cells by regulating the actin cytoskeleton through Rac1 signaling activation","volume":"37","author":"Ye","year":"2018","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.anireprosci.2021.106837_bib32","doi-asserted-by":"crossref","first-page":"2844","DOI":"10.1091\/mbc.e16-06-0429","article-title":"Formin-mediated actin polymerization at cell-cell junctions stabilizes E-cadherin and maintains monolayer integrity during wound repair","volume":"27","author":"Zaidel-Bar","year":"2016","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.anireprosci.2021.106837_bib33","doi-asserted-by":"crossref","first-page":"15224","DOI":"10.1371\/journal.pone.0015224","article-title":"Integrated profiling of microRNAs and mRNAs: microRNAs located on Xq27.3 associate with clear cell renal cell carcinoma","volume":"5","author":"Zhou","year":"2010","journal-title":"PLoS One"}],"container-title":["Animal Reproduction Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432021001524?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432021001524?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T06:45:54Z","timestamp":1759905954000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378432021001524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":33,"alternative-id":["S0378432021001524"],"URL":"https:\/\/doi.org\/10.1016\/j.anireprosci.2021.106837","relation":{},"ISSN":["0378-4320"],"issn-type":[{"value":"0378-4320","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MicroRNAs are potential regulators of the timed artificial insemination effect in gilt endometrium","name":"articletitle","label":"Article Title"},{"value":"Animal Reproduction Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anireprosci.2021.106837","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106837"}}