{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T17:17:31Z","timestamp":1778692651378,"version":"3.51.4"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010435","name":"Universidade Federal Fluminense","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010435","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004586","name":"FAPERJ","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005639","name":"Universidade de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005639","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Animal Reproduction Science"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.anireprosci.2024.107595","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T02:54:57Z","timestamp":1724986497000},"page":"107595","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["The effect of flunixin meglumine on the premature regression of corpus luteum, recovery rate, and embryo production in superovulated Dorper ewes"],"prefix":"10.1016","volume":"270","author":[{"given":"Ana Lucia Rosa e Silva","family":"Maia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas Machado","family":"Figueira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcela Sene","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasmine Bantim de Souza","family":"Pinheiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thais de Almeida","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe Zandonadi","family":"Brand\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeferson Ferreira","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Emilia Franco","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio Alvarenga de","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna Maria Gon\u00e7alves","family":"Souza-Fabjan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.anireprosci.2024.107595_bib1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.smallrumres.2004.11.008","article-title":"Effect of flunixin meglumine on the corpus luteum and possible prevention of embryonic loss in Pelibuey ewes","volume":"59","author":"Ak\u00e9-L\u00f3pez","year":"2005","journal-title":"Small Rumin. Res."},{"key":"10.1016\/j.anireprosci.2024.107595_bib2","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1007\/s11250-013-0361-z","article-title":"Assessing carcass and meat characteristics of Damara, Dorper and Australian Merino lambs under restricted feeding","volume":"45","author":"Almeida","year":"2013","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.anireprosci.2024.107595_bib3","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0093-691X(87)90084-7","article-title":"Corpus luteum (CL) failure and embryonic loss in superovulated goats","volume":"27","author":"Armstrong","year":"1987","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107595_bib4","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.theriogenology.2016.04.024","article-title":"Intrinsic determinants and predictors of superovulatory yields in sheep circulating concentrations of reproductive hormones, ovarian status, and antral follicular blood flow","volume":"86","author":"Bartlewski","year":"2016","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107595_bib5","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1530\/jrf.0.0840425","article-title":"Evidence for prostaglandin involvement in early luteal regression of the superovulated nanny goat (Capra hircus)","volume":"84","author":"Battye","year":"1988","journal-title":"J. Reprod. Fert."},{"key":"10.1016\/j.anireprosci.2024.107595_bib6","doi-asserted-by":"crossref","first-page":"56","DOI":"10.5380\/avs.v25i1.70477","article-title":"Effect of flunixin meglumine and hCG at commercial programs for multiple ovulation and embryo transfer (MOET) in sheep","volume":"25","author":"Bergstein-Galan","year":"2020","journal-title":"Arch. Vet. Sci."},{"key":"10.1016\/j.anireprosci.2024.107595_bib7","doi-asserted-by":"crossref","first-page":"873","DOI":"10.3390\/ani13050873","article-title":"Luteal function, biometrics, and echotextural attributes in santa in\u00eas ewes superovulated with different total doses of porcine follicle-stimulating hormone","volume":"13","author":"Bevilaqua","year":"2023","journal-title":"Animals"},{"key":"10.1016\/j.anireprosci.2024.107595_bib8","first-page":"7","article-title":"Sex steroid-mediated control of oviductal function in cattle","volume":"2","author":"Binelli","year":"2018","journal-title":"Biology"},{"key":"10.1016\/j.anireprosci.2024.107595_bib9","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.smallrumres.2014.04.002","article-title":"Repeatability of superovulatory response to successive FSH treatments in Merino sheep","volume":"120","author":"Bruno-Galarraga","year":"2014","journal-title":"Small Rumin. Res."},{"key":"10.1016\/j.anireprosci.2024.107595_bib10","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.anireprosci.2006.01.008","article-title":"Use of fluorogestone acetate after breeding to reduce the effect of premature luteal regression in dairy goats when superovulation is induced with FSH","volume":"97","author":"Cervantes","year":"2007","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.anireprosci.2024.107595_bib11","series-title":"Manual para exame androl\u00f3gico e avalia\u00e7\u00e3o de s\u00eamen animal","first-page":"87","author":"Col\u00e9gio Brasileiro de Reprodu\u00e7\u00e3o Animal (CBRA)","year":"2013"},{"key":"10.1016\/j.anireprosci.2024.107595_bib12","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/S0378-4320(00)00080-4","article-title":"What is stress, and how does it affect reproduction?","volume":"60\u201361","author":"Dobson","year":"2000","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.anireprosci.2024.107595_bib13","first-page":"1299","article-title":"Morphometric analysis of cell types in the ovine corpus luteum throughout the estrous cycle. Biol. Reprod","volume":"35","author":"Farin","year":"1986"},{"key":"10.1016\/j.anireprosci.2024.107595_bib14","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/rda.12543","article-title":"Colour doppler ultrasonography as a tool to assess luteal function in Santa In\u00eas Ewes","volume":"50","author":"Figueira","year":"2015","journal-title":"Reprod. Domest. Anim."},{"key":"10.1016\/j.anireprosci.2024.107595_bib15","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.theriogenology.2020.06.004","article-title":"Embryo yield and quality are associated with progestogen treatment during superovulation protocol in lactating Lacaune ewes","volume":"155","author":"Figueira","year":"2020","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107595_bib16","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1095\/biolreprod.108.074336","article-title":"Progesterone-regulated changes in endometrial gene expression contribute to advanced conceptus development in cattle","volume":"81","author":"Forde","year":"2009","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.anireprosci.2024.107595_bib17","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/0093-691X(90)90654-C","article-title":"Comparison of a progesterone intravaginal device (CIDR\u2122) with flunixin meglumine (Finadyne\u2122) for reducing the effects of corpora lutea regression in the goat","volume":"33","author":"Gilbert","year":"1990","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107595_bib18","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s11250-021-02932-8","article-title":"Approaches of estrous synchronization in sheep: developments during the last two decades: a review","volume":"53","author":"Hameed","year":"2021","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.anireprosci.2024.107595_bib19","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1007\/s11250-020-02283-w","article-title":"Production performance of sheep and goat breeds at a farm in a semi-arid region of Namibia","volume":"52","author":"Kandiwa","year":"2020","journal-title":"Trop. Anim. Health. Prod."},{"issue":"187","key":"10.1016\/j.anireprosci.2024.107595_bib20","article-title":"Embryo development is impaired in goats that are treated for hydrometra and subsequently subjected to superovulation","volume":"14","author":"Maia","year":"2020","journal-title":"Vet. Rec."},{"key":"10.1016\/j.anireprosci.2024.107595_bib21","series-title":"Nutrient requirements of small ruminants: sheep, goats, cervids, and new world camelids","author":"National Research Council (NRC)","year":"2007"},{"key":"10.1016\/j.anireprosci.2024.107595_bib22","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1262\/jrd.46.397","article-title":"Incidence of abnormal corpus luteum in superovulated ewes","volume":"46","author":"Okada","year":"2000","journal-title":"J. Reprod. Dev."},{"key":"10.1016\/j.anireprosci.2024.107595_bib23","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1111\/rda.13165","article-title":"Assessing the usefulness of B-mode and colour Doppler sonography, and measurements of circulating progesterone concentrations for determining ovarian responses in superovulated ewes","volume":"53","author":"Oliveira","year":"2018","journal-title":"Reprod. Domest. Anim."},{"key":"10.1016\/j.anireprosci.2024.107595_bib24","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0034-5288(18)33460-X","article-title":"Some behavioural and physiological changes in pregnant goats and sheep during adaptation to laboratory conditions","volume":"20","author":"Pearson","year":"1976","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.anireprosci.2024.107595_bib25","doi-asserted-by":"crossref","first-page":"266e9","DOI":"10.1111\/rda.13089","article-title":"Colour-Doppler ultrasound imaging as a laparoscopy substitute to count corpora lutea in superovulated sheep","volume":"53","author":"Pinto","year":"2018","journal-title":"Reprod Domest Anim"},{"key":"10.1016\/j.anireprosci.2024.107595_bib26","volume":"10","author":"Rocha","year":"2021","journal-title":"Res., Soc. Dev."},{"key":"10.1016\/j.anireprosci.2024.107595_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.livsci.2021.104808","article-title":"Occurrence of premature regression of corpus luteum in MOET programs in Dorper ewes under subtropical climate","volume":"255","author":"Rocha","year":"2022","journal-title":"Livest. Sci."},{"key":"10.1016\/j.anireprosci.2024.107595_bib28","first-page":"270","article-title":"Premature luteal regression in small ruminants","volume":"39","author":"Rodriguez","year":"2015","journal-title":"Rev. Bras. Reprod. Anim."},{"key":"10.1016\/j.anireprosci.2024.107595_bib29","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.3168\/jds.2009-2605","article-title":"Contribution of the female reproductive tract to low fertility in postpartum lactating dairy cows","volume":"93","author":"Rizos","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.anireprosci.2024.107595_bib30","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/0093-691X(90)90005-E","article-title":"Human menopausal gonadotropin induces ovulation in sheep, but embryo recovery after prostaglandin F2alpha synchronization is compromised by premature luteal regression","volume":"34","author":"Schiewe","year":"1990","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107595_bib31","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/S0093-691X(98)00206-4","article-title":"Premature luteal regression in goats superovulated with PMSG: effect of hCG or GnRH administration during the early luteal phase","volume":"50","author":"Saharrea","year":"1998","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107595_bib32","first-page":"69","article-title":"Different flunixin meglumine administrations to control of the corpus luteum premature regression in superovulated goats","volume":"8","author":"Salles","year":"1998","journal-title":"Ci\u00eancia Anim."},{"key":"10.1016\/j.anireprosci.2024.107595_bib33","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1111\/rda.14094","article-title":"Comparison of GnRH and hCG effects on oestradiol, progesterone and premature luteolysis in Ovsynch-synchronized ewes","volume":"57","author":"Salloum","year":"2022","journal-title":"Reprod. Domest. Anim."},{"key":"10.1016\/j.anireprosci.2024.107595_bib34","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.theriogenology.2017.07.036","article-title":"Effect of different hormonal combinations on follicular wave emergence and superovulatory response in sheep","volume":"103","author":"Souza-Fabjan","year":"2017","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107595_bib35","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.smallrumres.2016.10.017","article-title":"Effect of the Dorper breed on the performance, carcass and meat traits of lambs bred from Santa In\u00eas sheep","volume":"145","author":"Souza","year":"2016","journal-title":"Small Rumin. Res."},{"key":"10.1016\/j.anireprosci.2024.107595_bib36","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1071\/RD20206","article-title":"In vitro production of small ruminant embryos: latest improvements and further research","volume":"33","author":"Souza-Fabjan","year":"2021","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.anireprosci.2024.107595_bib37","unstructured":"Stringfellow, D.A., Givens, M.D., 2010. Manual of the International Embryo Transfer Society (IETS). fourth ed. Savoy, IL."},{"key":"10.1016\/j.anireprosci.2024.107595_bib38","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ijvsm.2018.02.003","article-title":"Advances in in vitro production of sheep embryos","volume":"6","author":"Zhu","year":"2018","journal-title":"Int. J. Vet. Sci."}],"container-title":["Animal Reproduction Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432024001866?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432024001866?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T16:54:15Z","timestamp":1778691255000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378432024001866"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":38,"alternative-id":["S0378432024001866"],"URL":"https:\/\/doi.org\/10.1016\/j.anireprosci.2024.107595","relation":{},"ISSN":["0378-4320"],"issn-type":[{"value":"0378-4320","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of flunixin meglumine on the premature regression of corpus luteum, recovery rate, and embryo production in superovulated Dorper ewes","name":"articletitle","label":"Article Title"},{"value":"Animal Reproduction Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anireprosci.2024.107595","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107595"}}