{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T16:14:55Z","timestamp":1784564095776,"version":"3.55.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Animal Reproduction Science"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.anireprosci.2024.107645","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T21:06:19Z","timestamp":1731704779000},"page":"107645","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Multiple mating enhances luteogenesis increasing corpus luteum perfusion area and progesterone production in ewes"],"prefix":"10.1016","volume":"272","author":[{"given":"J.P.","family":"Bottino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.G.K.","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Ratto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Ungerfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anireprosci.2024.107645_bib1","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/0031-9384(70)90155-1","article-title":"The effect of copulatory behavior on hormonal change in the female rat prior to implantation","volume":"5","author":"Adler","year":"1970","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.anireprosci.2024.107645_bib2","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0378-4320(82)90033-1","article-title":"Ovarian responses of anoestrous goats to stimulation with pregnant mare serum gonadotrophin","volume":"5","author":"Armstrong","year":"1982","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.anireprosci.2024.107645_bib3","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1095\/biolreprod1.2.152","article-title":"Quantitative changes in pituitary acidophils in cycling and mated Syrian hamsters","volume":"1","author":"Avery","year":"1969","journal-title":"Biol. Reprod."},{"issue":"3","key":"10.1016\/j.anireprosci.2024.107645_bib4","doi-asserted-by":"crossref","DOI":"10.1590\/1984-3143-ar2021-0045","article-title":"Multiple matings modify the estrous length, the moment of ovulation, and the estradiol and LH patterns in ewes","volume":"18","author":"Bottino","year":"2021","journal-title":"Anim. Reprod."},{"key":"10.1016\/j.anireprosci.2024.107645_bib5","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1530\/rep.1.00382","article-title":"Corpora lutea induced by gonadotrophin-release hormone treatment of anoestrous Welsh Mountain ewes: reduced sensitivity to luteinizing hormone in vivo and to chorionic gonadotrophin in vitro.","volume":"129","author":"Bramley","year":"2005","journal-title":"Reproduction"},{"key":"10.1016\/j.anireprosci.2024.107645_bib6","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1095\/biolreprod47.3.355","article-title":"Gonadotropin surge increases fluorescent-tagged low-density lipoprotein uptake by macaque granulosa cells from preovulatory follicles","volume":"47","author":"Brannian","year":"1992","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.anireprosci.2024.107645_bib7","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1051\/rnd:2006022","article-title":"Male-induced short oestrous and ovarian cycles in sheep and goats: a working hypothesis","volume":"46","author":"Chemineau","year":"2006","journal-title":"Reprod. Nutr. Dev."},{"key":"10.1016\/j.anireprosci.2024.107645_bib8","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1210\/en.2008-0619","article-title":"Expression of scavenger receptor-BI and low-density lipoprotein receptor and differential use of lipoproteins to support early steroidogenesis in luteinizing macaque granulosa cells","volume":"150","author":"Cherian-Shaw","year":"2009","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2024.107645_bib9","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.theriogenology.2009.10.011","article-title":"The expression of angiogenic growth factors and their receptors in ovarian follicles throughout the estrus cycle in the ewe","volume":"73","author":"Chowdhury","year":"2010","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107645_bib10","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jprot.2013.05.029","article-title":"Proteomic characterization and cross species comparison of mammalian seminal plasma","volume":"91","author":"Druart","year":"2013","journal-title":"J. Proteom."},{"key":"10.1016\/j.anireprosci.2024.107645_bib11","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1530\/jrf.0.0160495","article-title":"Failure of hypophysectomy to affect regression of cyclic hamster corpus luteum","volume":"16","author":"Greenwald","year":"1968","journal-title":"J. Reprod. Fert."},{"key":"10.1016\/j.anireprosci.2024.107645_bib12","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.theriogenology.2009.11.016","article-title":"Lutel blood flow is a more appropriate indicator for luteal function during the bovine estrous cycle than luteal size","volume":"73","author":"Herzog","year":"2010","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107645_bib13","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.theriogenology.2007.10.004","article-title":"Ovsynch synchronization and fixed-time insemination in goats","volume":"69","author":"Holtz","year":"2008","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107645_bib14","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1530\/jrf.0.0760349","article-title":"Progesterone pretreatment has a different effect on GnRH-induced preovulatory follicles to determine their ability to develop into normal corpora lutea in anoestrous ewes","volume":"76","author":"Hunter","year":"1986","journal-title":"J. Reprod. Fertil."},{"key":"10.1016\/j.anireprosci.2024.107645_bib15","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1095\/biolreprod51.3.380","article-title":"Steady-state concentrations of messenger ribonucleic acid encoding cytochrome P450 side-chain clevage and 3\u03b2-hydroxysteroid dehydrogenase 5\/4 isomerase in ovine corpora lutea during the estrous cycle","volume":"51","author":"Juengel","year":"1994","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.anireprosci.2024.107645_bib16","doi-asserted-by":"crossref","first-page":"5423","DOI":"10.1210\/endo.136.12.7588291","article-title":"Hormonal regulation of ribonucleic acid encoding steroidogenic acute regulatory protein in ovine corpora lutea","volume":"136","author":"Juengel","year":"1995","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2024.107645_bib17","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.theriogenology.2016.08.022","article-title":"Association of luteal blood flow with follicular size, serum oestrogen and progesterone concentrations, and the inducibility of luteolysis by PGF2\u03b1 in dairy cows","volume":"87","author":"Kaya","year":"2016","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107645_bib18","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/0031-9384(75)90208-5","article-title":"Influence of the presence of rams on the timing of ovulation and discharge of LH in ewes","volume":"15","author":"Lindsay","year":"1975","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.anireprosci.2024.107645_bib19","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1071\/RD15326","article-title":"Role of progesterone in embryo development in cattle","volume":"28","author":"Lonergan","year":"2016","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.anireprosci.2024.107645_bib20","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1095\/biolreprod.102.011155","article-title":"Insuline-like growth factors-1 and -2, but not hypoxia, synergize with gonadotropin hormone to promote vascular endothelial growth factor-A secretion by monkey granulosa cells from periovulatory follicles","volume":"68","author":"Martinez-Chequer","year":"2003","journal-title":"Biol. Reprod."},{"issue":"8","key":"10.1016\/j.anireprosci.2024.107645_bib21","doi-asserted-by":"crossref","first-page":"3480","DOI":"10.1210\/endo.139.8.6137","article-title":"Luteal dysfunction in ewes induced to ovulate early in the follicular phase","volume":"139","author":"Murdoch","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.anireprosci.2024.107645_bib22","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/0093-691X(94)90455-R","article-title":"Effects of different stimuli of service on estrus duration in dairy goats","volume":"42","author":"Romano","year":"1994","journal-title":"Theriogenology"},{"issue":"1-2","key":"10.1016\/j.anireprosci.2024.107645_bib23","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0378-4320(96)01633-8","article-title":"Effect of service on duration of oestrus and ovulation in dairy goats","volume":"47","author":"Romano","year":"1997","journal-title":"Anim. Reprod. Sci."},{"issue":"2","key":"10.1016\/j.anireprosci.2024.107645_bib24","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.theriogenology.2015.09.021","article-title":"Effect of copulation on estrus duration and ovulation time in goats","volume":"85","author":"Romano","year":"2016","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107645_bib25","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH Image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.anireprosci.2024.107645_bib26","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1016\/j.theriogenology.2012.03.036","article-title":"Effect of purified llama ovulation-inducing factor (OIF) on ovarian function in cattle","volume":"78","author":"Tanco","year":"2012","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2024.107645_bib27","doi-asserted-by":"crossref","DOI":"10.1071\/RD15223","article-title":"Follicle vascularity coordinates corpus luteum blood flow and progesterone production","volume":"29","author":"de Tarso","year":"2017","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.anireprosci.2024.107645_bib28","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1016\/j.theriogenology.2014.01.038","article-title":"Luteotrophic effect of ovulation-inducing factor\/nerve growth factor present in the seminal plasma of llamas","volume":"81","author":"Ulloa-Leal","year":"2014","journal-title":"Theriogenology"}],"container-title":["Animal Reproduction Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432024002458?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432024002458?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T11:51:03Z","timestamp":1734349863000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378432024002458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":28,"alternative-id":["S0378432024002458"],"URL":"https:\/\/doi.org\/10.1016\/j.anireprosci.2024.107645","relation":{},"ISSN":["0378-4320"],"issn-type":[{"value":"0378-4320","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiple mating enhances luteogenesis increasing corpus luteum perfusion area and progesterone production in ewes","name":"articletitle","label":"Article Title"},{"value":"Animal Reproduction Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anireprosci.2024.107645","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107645"}}