{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T22:36:29Z","timestamp":1784759789333,"version":"3.55.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100015956","name":"Special Project for Research and Development in Key areas of Guangdong Province","doi-asserted-by":"publisher","award":["2022B0202090002"],"award-info":[{"award-number":["2022B0202090002"]}],"id":[{"id":"10.13039\/501100015956","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015335","name":"Modern Agricultural Technology Industry System of Shandong province","doi-asserted-by":"publisher","award":["CARS-PIG-35"],"award-info":[{"award-number":["CARS-PIG-35"]}],"id":[{"id":"10.13039\/501100015335","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004607","name":"Natural Science Foundation of Guangxi Province","doi-asserted-by":"publisher","award":["2025GXNSFAA069199"],"award-info":[{"award-number":["2025GXNSFAA069199"]}],"id":[{"id":"10.13039\/501100004607","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Animal Reproduction Science"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.anireprosci.2025.107998","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T07:55:50Z","timestamp":1758614150000},"page":"107998","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["The cryoprotective effect of virgin coconut oil on boar sperm: Enhancing sperm quality and reproductive performance"],"prefix":"10.1016","volume":"282","author":[{"given":"Shu","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"QianXi","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhili","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanwei","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunxiang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.anireprosci.2025.107998_bib1","doi-asserted-by":"crossref","first-page":"3056","DOI":"10.1182\/bloodadvances.2024015439","article-title":"Neuroprotective, anti-inflammatory, and analgesic activity of palmitoylethanolamide in sickle cell mice","volume":"9","author":"Argueta","year":"2025","journal-title":"Blood Adv."},{"issue":"8","key":"10.1016\/j.anireprosci.2025.107998_bib2","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.3390\/life12081155","article-title":"Cryopreservation of pig semen using a Quercetin-Supplemented freezing extender","volume":"12","author":"Bang","year":"2022","journal-title":"Life"},{"issue":"6","key":"10.1016\/j.anireprosci.2025.107998_bib3","doi-asserted-by":"crossref","first-page":"624","DOI":"10.3390\/antiox13060624","article-title":"Advancements in understanding and enhancing Antioxidant-Mediated sperm cryopreservation in small ruminants: challenges and perspectives","volume":"13","author":"Berean","year":"2024","journal-title":"Antioxidants"},{"key":"10.1016\/j.anireprosci.2025.107998_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.anireprosci.2024.107496","article-title":"Boar semen cryopreservation: state of the art, and international trade vision","volume":"269","author":"Bolarin","year":"2024","journal-title":"Anim. Reprod. Sci."},{"issue":"3","key":"10.1016\/j.anireprosci.2025.107998_bib5","doi-asserted-by":"crossref","first-page":"779","DOI":"10.2527\/jas.2011-4311","article-title":"Application of computer-assisted semen analysis to explain variations in pig fertility","volume":"90","author":"Broekhuijse","year":"2012","journal-title":"J. Anim. Sci."},{"issue":"3","key":"10.1016\/j.anireprosci.2025.107998_bib6","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1530\/rep.0.1210395","article-title":"Changes in sperm quality and lipid composition during cryopreservation of boar semen","volume":"121","author":"Cerolini","year":"2001","journal-title":"Reproduction"},{"key":"10.1016\/j.anireprosci.2025.107998_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.anireprosci.2024.107547","article-title":"Insights into crucial molecules and protein channels involved in pig sperm cryopreservation","volume":"269","author":"Delgado-Berm\u00fadez","year":"2024","journal-title":"Anim. Reprod. Sci."},{"issue":"2","key":"10.1016\/j.anireprosci.2025.107998_bib8","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.theriogenology.2007.04.048","article-title":"Cryopreservation of goat spermatozoa: comparison of two freezing extenders based on post-thaw sperm quality and fertility rates after artificial insemination","volume":"68","author":"Dorado","year":"2007","journal-title":"Theriogenology"},{"issue":"20","key":"10.1016\/j.anireprosci.2025.107998_bib9","doi-asserted-by":"crossref","first-page":"3679","DOI":"10.3390\/molecules24203679","article-title":"Limonin: a review of its pharmacology, toxicity, and pharmacokinetics","volume":"24","author":"Fan","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.anireprosci.2025.107998_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2019.06.004","article-title":"Effects of cryopreservation on mitochondrial function and sperm quality in fish","volume":"511","author":"Figueroa","year":"2019","journal-title":"Aquaculture"},{"issue":"3-4","key":"10.1016\/j.anireprosci.2025.107998_bib11","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.anireprosci.2006.06.003","article-title":"Effect of different procedures of ejaculate collection, extenders and packages on DNA integrity of boar spermatozoa following freezing-thawing","volume":"99","author":"Fraser","year":"2007","journal-title":"Anim. Reprod. Sci."},{"issue":"4","key":"10.1016\/j.anireprosci.2025.107998_bib12","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/rda.13409","article-title":"Recent advances in bovine sperm cryopreservation techniques with a focus on sperm post-thaw quality optimization","volume":"54","author":"Gr\u00f6tter","year":"2019","journal-title":"Reprod. Domest. Anim. = Zuchthyg."},{"issue":"3","key":"10.1016\/j.anireprosci.2025.107998_bib13","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.rbmo.2018.05.012","article-title":"Sperm cryopreservation: a review on current molecular cryobiology and advanced approaches","volume":"37","author":"Hezavehei","year":"2018","journal-title":"Reprod. Biomed. Online"},{"issue":"2","key":"10.1016\/j.anireprosci.2025.107998_bib14","first-page":"160","article-title":"Pemberian virgin coconut oil untuk meningkatkan jumlah dan motilitas spermatozoa: studi pada tikus wistar dengan diet tinggi lemak","volume":"37","author":"Jasda","year":"2014","journal-title":"Penelit. Gizi Dan. Makanan ( J. Nutr. Food Res."},{"key":"10.1016\/j.anireprosci.2025.107998_bib15","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.theriogenology.2024.01.025","article-title":"Effects of limonin on oxidative stress and early apoptosis in oocytes during in vitro maturation","volume":"218","author":"Jiao","year":"2024","journal-title":"Theriogenology"},{"key":"10.1016\/j.anireprosci.2025.107998_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.cryobiol.2025.105277","article-title":"Supplemental effect of metallic nanoparticles on cryopreserved semen quality, lipid peroxidation, sperm head ultrastructure and field fertility levels in crossbred (Hampshire x Niang Megha) boars","volume":"120","author":"Kalita","year":"2025","journal-title":"Cryobiology"},{"issue":"2","key":"10.1016\/j.anireprosci.2025.107998_bib17","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/rda.12552","article-title":"The fertility of frozen boar sperm when used for artificial insemination","volume":"50","author":"Knox","year":"2015","journal-title":"Reprod. Domest. Anim. = Zuchthyg."},{"issue":"9","key":"10.1016\/j.anireprosci.2025.107998_bib18","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M900538-MCP200","article-title":"Liver membrane proteome glycosylation changes in mice bearing an extra-hepatic tumor","volume":"10","author":"Lee","year":"2011","journal-title":"Mol. Cell. Proteom. MCP"},{"issue":"1","key":"10.1016\/j.anireprosci.2025.107998_bib19","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1186\/s12864-018-5132-9","article-title":"High throughput small RNA and transcriptome sequencing reveal capacitation-related microRNAs and mRNA in boar sperm","volume":"19","author":"Li","year":"2018","journal-title":"BMC Genom."},{"key":"10.1016\/j.anireprosci.2025.107998_bib20","article-title":"Limonin alleviates Non-alcoholic fatty liver disease by reducing lipid accumulation, suppressing inflammation and oxidative stress","volume":"12","author":"Li","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"11","key":"10.1016\/j.anireprosci.2025.107998_bib21","first-page":"1692","article-title":"Supplemental effect of different levels of taurine in modena on boar semen quality during liquid preservation at 17\u00b0C","volume":"88","author":"Li","year":"2017","journal-title":"Anim. Sci. J. = Nihon chikusan Gakkaiho"},{"issue":"12","key":"10.1016\/j.anireprosci.2025.107998_bib22","doi-asserted-by":"crossref","first-page":"5637","DOI":"10.2527\/jas.2013-6867","article-title":"Effect of using frozen-thawed boar sperm differing in post-thaw motility in the first and second inseminations on pregnancy establishment, litter size, and fetal paternity in relation to time of ovulation","volume":"91","author":"McNamara","year":"2013","journal-title":"J. Anim. Sci."},{"issue":"1","key":"10.1016\/j.anireprosci.2025.107998_bib23","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0093-691X(01)00674-4","article-title":"Current status of sperm cryopreservation: why isn't it better?","volume":"57","author":"Medeiros","year":"2002","journal-title":"Theriogenology"},{"issue":"1","key":"10.1016\/j.anireprosci.2025.107998_bib24","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1093\/biolre\/ioae043","article-title":"Metabolic pathways for glucose and fructose: I synthesis and metabolism of fructose by ovine conceptuses","volume":"111","author":"Moses","year":"2024","journal-title":"Biol. Reprod."},{"issue":"4","key":"10.1016\/j.anireprosci.2025.107998_bib25","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/andr.12490","article-title":"Virgin coconut oil extract mitigates testicular-induced toxicity of alcohol use in antiretroviral therapy","volume":"6","author":"Ogedengbe","year":"2018","journal-title":"Andrology"},{"issue":"1","key":"10.1016\/j.anireprosci.2025.107998_bib26","doi-asserted-by":"crossref","first-page":"326","DOI":"10.21037\/jgo-21-906","article-title":"Integrated omics analysis: the relationship between significantly increased klebsiella post-hepatectomy and decreased hub-metabolite 3-methyl-2-oxobutanoic acid is associated with induced liver failure","volume":"13","author":"Peng","year":"2022","journal-title":"J. Gastrointest. Oncol."},{"issue":"8","key":"10.1016\/j.anireprosci.2025.107998_bib27","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.3390\/ijms21082781","article-title":"Sperm cryodamage in ruminants: understanding the molecular changes induced by the cryopreservation process to optimize sperm quality","volume":"21","author":"Peris-Frau","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.anireprosci.2025.107998_bib28","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.smallrumres.2005.02.015","article-title":"A review on goat sperm cryopreservation","volume":"63","author":"Purdy","year":"2006","journal-title":"Small Rumin. Res."},{"key":"10.1016\/j.anireprosci.2025.107998_bib29","article-title":"Identification of fatty acids in virgin coconut oil (VCO), cocoa beans, crude palm oil (CPO), and palm kernel beans using gas chromatography","volume":"1083","author":"Sabahannur","year":"2022"},{"issue":"4","key":"10.1016\/j.anireprosci.2025.107998_bib30","doi-asserted-by":"crossref","first-page":"616","DOI":"10.3390\/molecules22040616","article-title":"Anti-Inflammatory, antioxidant and crystallographic studies of N-Palmitoyl-ethanol amine (PEA) derivatives","volume":"22","author":"Saturnino","year":"2017","journal-title":"Molecules"},{"issue":"32","key":"10.1016\/j.anireprosci.2025.107998_bib31","doi-asserted-by":"crossref","first-page":"29442","DOI":"10.1074\/jbc.M303432200","article-title":"A flux model of glycolysis and the oxidative pentosephosphate pathway in developing brassica napus embryos","volume":"278","author":"Schwender","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"7","key":"10.1016\/j.anireprosci.2025.107998_bib32","doi-asserted-by":"crossref","DOI":"10.1093\/jas\/skac169","article-title":"A novel experimental design for boar sperm cryopreservation","volume":"100","author":"Shepherd","year":"2022","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.anireprosci.2025.107998_bib33","article-title":"Associations of sperm mtDNA copy number, DNA fragmentation index, and reactive oxygen species with clinical outcomes in ART treatments","volume":"13","author":"Shi","year":"2022","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.anireprosci.2025.107998_bib34","first-page":"349","article-title":"The \u201cKor towska\u201d method of freezing boar semen","volume":"41","author":"Strzezek","year":"1985","journal-title":"Med. Weter."},{"key":"10.1016\/j.anireprosci.2025.107998_bib35","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.theriogenology.2021.12.030","article-title":"Addition of l-carnitine to the freezing extender improves post-thaw sperm quality of okinawan native agu pig","volume":"188","author":"Tatemoto","year":"2022","journal-title":"Theriogenology"},{"issue":"3","key":"10.1016\/j.anireprosci.2025.107998_bib36","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1002\/j.1939-4640.2001.tb02194.x","article-title":"Morphologically distinct sperm subpopulations defined by Fourier shape descriptors in fresh ejaculates correlate with variation in boar semen quality following cryopreservation","volume":"22","author":"Thurston","year":"2001","journal-title":"J. Androl."},{"issue":"2","key":"10.1016\/j.anireprosci.2025.107998_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.100906","article-title":"Sialic acid O-acetylation: from biosynthesis to roles in health and disease","volume":"297","author":"Visser","year":"2021","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.anireprosci.2025.107998_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.anireprosci.2021.106904","article-title":"Advances in sperm cryopreservation in farm animals: cattle, horse, pig and sheep","volume":"246","author":"Y\u00e1nez-Ortiz","year":"2022","journal-title":"Anim. Reprod. Sci."},{"issue":"1","key":"10.1016\/j.anireprosci.2025.107998_bib39","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.theriogenology.2015.09.047","article-title":"Sperm cryopreservation update: cryodamage, markers, and factors affecting the sperm freezability in pigs","volume":"85","author":"Yeste","year":"2016","journal-title":"Theriogenology"},{"issue":"6","key":"10.1016\/j.anireprosci.2025.107998_bib40","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1021\/jf0484632","article-title":"Antioxidant activity of citrus limonoids, flavonoids, and coumarins","volume":"53","author":"Yu","year":"2005","journal-title":"J. Agric. Food Chem."}],"container-title":["Animal Reproduction Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432025002374?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378432025002374?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:52:09Z","timestamp":1773125529000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378432025002374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":40,"alternative-id":["S0378432025002374"],"URL":"https:\/\/doi.org\/10.1016\/j.anireprosci.2025.107998","relation":{},"ISSN":["0378-4320"],"issn-type":[{"value":"0378-4320","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The cryoprotective effect of virgin coconut oil on boar sperm: Enhancing sperm quality and reproductive performance","name":"articletitle","label":"Article Title"},{"value":"Animal Reproduction Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anireprosci.2025.107998","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"107998"}}