{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T16:20:05Z","timestamp":1774714805385,"version":"3.50.1"},"reference-count":15,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["JP16K20249"],"award-info":[{"award-number":["JP16K20249"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Auris Nasus Larynx"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.anl.2019.01.010","type":"journal-article","created":{"date-parts":[[2019,2,10]],"date-time":"2019-02-10T01:32:13Z","timestamp":1549762333000},"page":"927-933","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Methotrexate-associated lymphoproliferative disorder with multiple pulmonary nodules and bilateral cervical lymphadenopathy"],"prefix":"10.1016","volume":"46","author":[{"given":"Seiichiro","family":"Makihara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin","family":"Kariya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mai","family":"Noujima-Harada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuya","family":"Ohara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Naito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junya","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Noda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuhiro","family":"Okano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Yoshino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunori","family":"Nishizaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.anl.2019.01.010_bib0005","first-page":"1741","article-title":"Lymphoma developing in a patient with rheumatoid arthritis taking low dose weekly methotrexate","volume":"18","author":"Ellman","year":"1991","journal-title":"J Rheumatol"},{"key":"10.1016\/j.anl.2019.01.010_bib0010","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.2169\/internalmedicine.54.3542","article-title":"Methotrexate-associated lymphoproliferative disease with multiple pulmonary nodules in a patient with rheumatoid arthritis","volume":"54","author":"Suemori","year":"2015","journal-title":"Intern Med"},{"key":"10.1016\/j.anl.2019.01.010_bib0015","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2017-221778","article-title":"Methotrexate-associated lymphoproliferative disease with multiple pulmonary nodules in a patient with rheumatoid arthritis","volume":"2017","author":"Lai","year":"2017","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.anl.2019.01.010_bib0020","first-page":"322","article-title":"Lymphoproliferative disorders in rheumatoid arthritis: clinicopathological analysis of 76 cases in relation to methotrexate medication","volume":"34","author":"Hoshida","year":"2007","journal-title":"J Rheumatol"},{"key":"10.1016\/j.anl.2019.01.010_bib0025","doi-asserted-by":"crossref","first-page":"3909","DOI":"10.1182\/blood.V99.11.3909","article-title":"Lymphomas in rheumatoid arthritis patients treated with methotrexate: a 3-year prospective study in France","volume":"99","author":"Mariette","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.anl.2019.01.010_bib0030","doi-asserted-by":"crossref","first-page":"616","DOI":"10.3109\/10428194.2011.625101","article-title":"Clinicopathological analyses in patients with other iatrogenic immunodeficiency-associated lymphoproliferative diseases and rheumatoid arthritis","volume":"53","author":"Tokuhira","year":"2012","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.anl.2019.01.010_bib0035","series-title":"WHO classification of tumours of Haematopoietic and lymphoid tissues","first-page":"350","author":"Swerdlow","year":"2008"},{"key":"10.1016\/j.anl.2019.01.010_bib0040","doi-asserted-by":"crossref","first-page":"594","DOI":"10.3950\/jibiinkoka.111.594","article-title":"Three cases of methotrexate-associated lymphoproliferative disorder (MTX-LPD)","volume":"111","author":"Ishida","year":"2008","journal-title":"Nippon Jibiinkoka Gakkai Kaiho"},{"key":"10.1016\/j.anl.2019.01.010_bib0045","first-page":"293","article-title":"Lymphoproliferative disorder in an elderly rheumatoid arthritis patient after longterm oral methotrexate administration: a case report","volume":"9","author":"Hashimoto","year":"2018","journal-title":"Mol Clin Oncol"},{"key":"10.1016\/j.anl.2019.01.010_bib0050","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/ejh.12116","article-title":"Methotrexate\/iatrogenic lymphoproliferative disorders in rheumatoid arthritis: histology, Epstein-Barr virus, and clonality are important predictors of disease progression and regression","volume":"91","author":"Ichikawa","year":"2013","journal-title":"Eur J Haematol"},{"key":"10.1016\/j.anl.2019.01.010_bib0055","doi-asserted-by":"crossref","first-page":"e105","DOI":"10.1016\/j.oooo.2014.02.029","article-title":"Methotrexate-associated lymphoproliferative disorder arising in the retromolar triangle and lung of a patient with rheumatoid arthritis","volume":"118","author":"Kudoh","year":"2014","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.anl.2019.01.010_bib0060","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.2169\/internalmedicine.53.2593","article-title":"Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis","volume":"53","author":"Oiwa","year":"2014","journal-title":"Intern Med"},{"key":"10.1016\/j.anl.2019.01.010_bib0065","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1080\/03009740600902403","article-title":"Methotrexate-related lymphomatoid granulomatosis: a case report of spontaneous regression of large tumours in multiple organs after cessation of methotrexate therapy in rheumatoid arthritis","volume":"36","author":"Shimada","year":"2007","journal-title":"Scand J Rheumatol"},{"key":"10.1016\/j.anl.2019.01.010_bib0070","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1007\/s00277-013-1741-1","article-title":"Reversible iatrogenic, MTX-associated EBV-driven lymphoproliferation with histopathological features of a lymphomatoid granulomatosis in a patient with rheumatoid arthritis","volume":"92","author":"Kobayashi","year":"2013","journal-title":"Ann Hematol"},{"key":"10.1016\/j.anl.2019.01.010_bib0075","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1007\/s10067-006-0480-2","article-title":"Lymphomatoid granulomatosis and diffuse alveolar damage associated with methotrexate therapy in a patient with rheumatoid arthritis","volume":"26","author":"Kameda","year":"2007","journal-title":"Clin Rheumatol"}],"container-title":["Auris Nasus Larynx"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0385814618307351?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0385814618307351?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T19:35:18Z","timestamp":1759952118000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0385814618307351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["S0385814618307351"],"URL":"https:\/\/doi.org\/10.1016\/j.anl.2019.01.010","relation":{},"ISSN":["0385-8146"],"issn-type":[{"value":"0385-8146","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Methotrexate-associated lymphoproliferative disorder with multiple pulmonary nodules and bilateral cervical lymphadenopathy","name":"articletitle","label":"Article Title"},{"value":"Auris Nasus Larynx","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anl.2019.01.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}