{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T05:31:23Z","timestamp":1790573483044,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T00:00:00Z","timestamp":1630368000000},"content-version":"am","delay-in-days":395,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Auris Nasus Larynx"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.anl.2020.02.001","type":"journal-article","created":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T09:32:52Z","timestamp":1582191172000},"page":"668-675","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Real-time imaging of head and neck squamous cell carcinomas using confocal micro-endoscopy and applicable dye: A preliminary study"],"prefix":"10.1016","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1794-2091","authenticated-orcid":false,"given":"Shogo","family":"Shinohara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuo","family":"Funabiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Kikuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Takebayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyomi","family":"Hamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9293-2064","authenticated-orcid":false,"given":"Shigeo","family":"Hara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiro","family":"Imai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Mizoguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anl.2020.02.001_bib0001","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1002\/cncr.20482","article-title":"Squamous cell carcinoma in situ at oropharyngeal and hypopharyngeal mucosal sites","volume":"101","author":"Muto","year":"2004","journal-title":"Cancer"},{"key":"10.1016\/j.anl.2020.02.001_bib0002","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1093\/jjco\/hyp001","article-title":"Metastatic neck disease beyond the limits of a neck dissection: attention to the 'para-hyoid' area in T1\/2 oral tongue cancer","volume":"39","author":"Ando","year":"2009","journal-title":"Jpn J Clin Oncol"},{"key":"10.1016\/j.anl.2020.02.001_bib0003","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1002\/hed.21964","article-title":"Value of narrow band imaging endoscopy in early mucosal head and neck cancer","volume":"34","author":"Lin","year":"2012","journal-title":"Head Neck"},{"key":"10.1016\/j.anl.2020.02.001_bib0004","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1111\/odi.12940","article-title":"Narrow-band imaging pattern classification in oral cavity","volume":"24","author":"Tirelli","year":"2018","journal-title":"Oral Dis"},{"key":"10.1016\/j.anl.2020.02.001_bib0005","first-page":"7","article-title":"Total excision of tongue leukoplakia for histopathological diagnosis","volume":"37","author":"Kurihara","year":"2011","journal-title":"Jpn J Head Neck Cancer"},{"key":"10.1016\/j.anl.2020.02.001_bib0006","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1055\/s-2000-654","article-title":"A novel method of virtual histopathology using laser-scanning confocal microscopy in-vitro with untreated fresh specimens from the gastrointestinal mucosa","volume":"32","author":"Inoue","year":"2000","journal-title":"Endoscopy"},{"key":"10.1016\/j.anl.2020.02.001_bib0007","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1055\/s-2003-44595","article-title":"Virtual histology of colorectal lesions using laser-scanning confocal microscopy","volume":"35","author":"Sakashita","year":"2003","journal-title":"Endoscopy"},{"key":"10.1016\/j.anl.2020.02.001_bib0008","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1007\/s00464-016-5003-x","article-title":"Probe-based confocal laser endomicroscopy for evaluating the submucosal invasion of colorectal neoplasms","volume":"31","author":"Kim","year":"2017","journal-title":"Surg Endosc"},{"key":"10.1016\/j.anl.2020.02.001_bib0009","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1007\/s00384-018-3059-x","article-title":"Pilot study on probe-based confocal laser endomicroscopy for colorectal neoplasms: an initial experience in Japan","volume":"33","author":"Abe","year":"2018","journal-title":"Int J Colorectal Dis"},{"key":"10.1016\/j.anl.2020.02.001_bib0010","doi-asserted-by":"crossref","first-page":"4473","DOI":"10.1007\/s00405-016-4145-8","article-title":"Noninvasive histological imaging of head and neck squamous cell carcinomas using confocal laser endomicroscopy","volume":"273","author":"Linxweiler","year":"2016","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.anl.2020.02.001_bib0011","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/MOO.0b013e32835df135","article-title":"Confocal laser endomicroscopy in head and neck cancer: steps forward?","volume":"21","author":"Volgger","year":"2013","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"issue":"Suppl 1","key":"10.1016\/j.anl.2020.02.001_bib0012","first-page":"E1419","article-title":"Automated analysis of confocal laser endomicroscopy images to detect head and neck cancer","volume":"38","author":"Dittberner","year":"2016","journal-title":"Head Neck"},{"key":"10.1016\/j.anl.2020.02.001_bib0013","doi-asserted-by":"crossref","first-page":"11979","DOI":"10.1038\/s41598-017-12320-8","article-title":"Automatic classification of cancerous tissue in laserendomicroscopy images of the oral cavity using deep learning","volume":"7","author":"Aubreville","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.anl.2020.02.001_bib0014","doi-asserted-by":"crossref","first-page":"3658","DOI":"10.1158\/1078-0432.CCR-14-3284","article-title":"Safety and tumor specificity of Cetuximab-IRDye800 for surgical navigation in head and neck cancer","volume":"21","author":"Rosenthal","year":"2015","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.anl.2020.02.001_bib0015","doi-asserted-by":"crossref","first-page":"6718","DOI":"10.1073\/pnas.1507121112","article-title":"Circuit-dependent striatal PKA and ERK signaling underlies rapid behavioral shift in mating reaction of male mice","volume":"112","author":"Goto","year":"2015","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.anl.2020.02.001_bib0016","doi-asserted-by":"crossref","first-page":"11383","DOI":"10.1073\/pnas.1514731112","article-title":"Role of PKA signaling in D2 receptor-expressing neurons in the core of the nucleus accumbens in aversive learning","volume":"112","author":"Yamaguchi","year":"2015","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.anl.2020.02.001_bib0017","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1097\/00005537-199910000-00029","article-title":"Noninvasive imaging of human oral mucosa in vivo by confocal reflectance microscopy","volume":"109","author":"White","year":"1999","journal-title":"Laryngoscope"},{"key":"10.1016\/j.anl.2020.02.001_bib0018","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1053\/j.gastro.2004.06.050","article-title":"Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo","volume":"127","author":"Kiesslich","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.anl.2020.02.001_bib0019","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1055\/s-0029-1214604","article-title":"In vivo diagnosis of acute intestinal graft-versus-host disease by confocal endomicroscopy","volume":"41","author":"Bojarski","year":"2009","journal-title":"Endoscopy"},{"key":"10.1016\/j.anl.2020.02.001_bib0020","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1111\/1759-7714.13089","article-title":"Probe-based confocal laser endomicroscopy for rapid on-site evaluation of transbronchial biopsy specimens","volume":"10","author":"Takemura","year":"2019","journal-title":"Thorac Cancer"},{"key":"10.1016\/j.anl.2020.02.001_bib0021","first-page":"2149","article-title":"Ozonation of mutagenic and carcinogenic polyaromatic amines and polyaromatic hydrocarbons in water","volume":"39","author":"Burleson","year":"1979","journal-title":"Cancer Res"},{"key":"10.1016\/j.anl.2020.02.001_bib0022","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1093\/carcin\/12.10.1751","article-title":"Carcinogenic properties of pharmaceutical agents evaluated in the IARC monographs programme","volume":"12","author":"Marselos","year":"1991","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.anl.2020.02.001_bib0023","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0753-3322(99)80007-9","article-title":"Data of pre-clinical and early clinical trials of acriflavine and hydroxy-methyl-ellipticine reviewed, enriched by the experience of their use for 18 months to 6 years in combinations with other HIV1 virostatics","volume":"52","author":"Mathe","year":"1998","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.anl.2020.02.001_bib0024","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1183\/09031936.00062512","article-title":"Confocal laser endomicroscopy for diagnosing lung cancer in vivo","volume":"41","author":"Fuchs","year":"2013","journal-title":"Eur Respir J"},{"key":"10.1016\/j.anl.2020.02.001_bib0025","first-page":"397","article-title":"Confocal endomicroscopic imaging of normal and neoplastic human tongue tissue using ALA-induced-PPIX fluorescence: a preliminary study","volume":"12","author":"Zheng","year":"2004","journal-title":"Oncol Rep"},{"key":"10.1016\/j.anl.2020.02.001_bib0026","first-page":"4714","article-title":"Confocal microscopy for real-time detection of oral cavity neoplasia","volume":"9","author":"Clark","year":"2003","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.anl.2020.02.001_bib0027","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.oraloncology.2008.02.002","article-title":"In vivo imaging of oral neoplasia using a miniaturized fiber optic confocal reflectance microscope","volume":"44","author":"Maitland","year":"2008","journal-title":"Oral Oncol"},{"key":"10.1016\/j.anl.2020.02.001_bib0028","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1002\/jemt.22535","article-title":"Real-time histological imaging of kidneys stained with food dyes using multiphoton microscopy","volume":"78","author":"Nagao","year":"2015","journal-title":"Microsc Res Tech"}],"container-title":["Auris Nasus Larynx"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0385814620300328?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0385814620300328?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T19:36:30Z","timestamp":1759952190000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0385814620300328"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["S0385814620300328"],"URL":"https:\/\/doi.org\/10.1016\/j.anl.2020.02.001","relation":{},"ISSN":["0385-8146"],"issn-type":[{"value":"0385-8146","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Real-time imaging of head and neck squamous cell carcinomas using confocal micro-endoscopy and applicable dye: A preliminary study","name":"articletitle","label":"Article Title"},{"value":"Auris Nasus Larynx","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anl.2020.02.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Oto-Rhino-Laryngological Society of Japan Inc. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}