{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:59:33Z","timestamp":1793041173190,"version":"4.5.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Auris Nasus Larynx"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.anl.2021.01.016","type":"journal-article","created":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T19:51:40Z","timestamp":1611949900000},"page":"991-998","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Contralateral lymph node recurrence rate and its prognostic factors in stage IVA-B well-lateralized oral cavity cancer"],"prefix":"10.1016","volume":"48","author":[{"given":"Ju-Chun","family":"Chien","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo-Chen","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Hsien","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien-Yu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bor-Hwang","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Shan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anl.2021.01.016_bib0001","first-page":"87","article-title":"Global cancer statistics, 2012","volume":"65","author":"Torre","year":"2015","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.anl.2021.01.016_bib0002","doi-asserted-by":"crossref","first-page":"e209","DOI":"10.4317\/jced.51163","article-title":"Occurrence of contralateral lymph neck node metastasis in patients with squamous cell carcinoma of the oral cavity","volume":"6","author":"Donaduzzi","year":"2014","journal-title":"J Clin Exp Dent"},{"key":"10.1016\/j.anl.2021.01.016_bib0003","doi-asserted-by":"crossref","first-page":"3624","DOI":"10.1002\/cncr.30227","article-title":"Proposing prognostic thresholds for lymph node yield in clinically lymph node-negative and lymph node-positive cancers of the oral cavity","volume":"122","author":"Kuo","year":"2016","journal-title":"Cancer"},{"key":"10.1016\/j.anl.2021.01.016_bib0004","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1200\/JCO.18.01921","article-title":"Management of the neck in squamous cell carcinoma of the oral cavity and oropharynx: ASCO clinical practice guideline","volume":"37","author":"Koyfman","year":"2019","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.anl.2021.01.016_bib0005","doi-asserted-by":"crossref","first-page":"180","DOI":"10.4248\/IJOS11068","article-title":"A review of clinical and histological parameters associated with contralateral neck metastases in oral squamous cell carcinoma","volume":"3","author":"Fan","year":"2011","journal-title":"Int J Oral Sci"},{"key":"10.1016\/j.anl.2021.01.016_bib0006","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/0002-9610(69)90208-6","article-title":"Contralateral spread of head and neck cancer","volume":"118","author":"Feind","year":"1969","journal-title":"Am J Surg"},{"key":"10.1016\/j.anl.2021.01.016_bib0007","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1245\/s10434-008-0196-4","article-title":"Risk stratification of patients with oral cavity squamous cell carcinoma and contralateral neck recurrence following radical surgery","volume":"16","author":"Liao","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.anl.2021.01.016_bib0008","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1002\/(SICI)1097-0347(199903)21:2<104::AID-HED2>3.0.CO;2-L","article-title":"Factors influencing contralateral lymph node metastasis from oral carcinoma","volume":"21","author":"Kowalski","year":"1999","journal-title":"Head Neck"},{"key":"10.1016\/j.anl.2021.01.016_bib0009","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1002\/hed.20423","article-title":"Management of contralateral N0 neck in oral cavity squamous cell carcinoma","volume":"28","author":"Koo","year":"2006","journal-title":"Head Neck"},{"key":"10.1016\/j.anl.2021.01.016_bib0010","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/j.joms.2008.01.012","article-title":"Contralateral lymph neck node metastasis of squamous cell carcinoma of the oral cavity: a retrospective analytic study in 315 patients","volume":"66","author":"Gonzalez-Garcia","year":"2008","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.anl.2021.01.016_bib0011","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.joms.2009.09.071","article-title":"Prognostic factors influencing contralateral neck lymph node metastases in oral and oropharyngeal carcinoma","volume":"68","author":"Capote-Moreno","year":"2010","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.anl.2021.01.016_bib0012","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/j.oraloncology.2004.04.004","article-title":"Clinical predictors for contralateral neck lymph node metastasis from unilateral squamous cell carcinoma in the oral cavity","volume":"40","author":"Kurita","year":"2004","journal-title":"Oral Oncol"},{"key":"10.1016\/j.anl.2021.01.016_bib0013","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.oraloncology.2014.08.003","article-title":"Risk factors and treatment of contralateral neck recurrence for unilateral oral squamous cell carcinoma: a retrospective study of 1482 cases","volume":"50","author":"Feng","year":"2014","journal-title":"Oral Oncol"},{"key":"10.1016\/j.anl.2021.01.016_bib0014","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1748-717X-4-33","article-title":"Ipsilateral irradiation for well lateralized carcinomas of the oral cavity and oropharynx: results on tumor control and xerostomia","volume":"4","author":"Cerezo","year":"2009","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.anl.2021.01.016_bib0015","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/hed.21436","article-title":"Frequency of bilateral cervical metastases in oropharyngeal squamous cell carcinoma: a retrospective analysis of 352 cases after bilateral neck dissection","volume":"33","author":"Olzowy","year":"2011","journal-title":"Head Neck"},{"key":"10.1016\/j.anl.2021.01.016_bib0016","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/j.ijrobp.2007.08.022","article-title":"Treatment outcome of combined modalities for buccal cancers: unilateral or bilateral neck radiation?","volume":"70","author":"Lin","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.anl.2021.01.016_bib0017","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1002\/lary.20141","article-title":"Primary tumor thickness as a risk factor for contralateral cervical metastases in T1\/T2 oral tongue squamous cell carcinoma","volume":"119","author":"Bier-Laning","year":"2009","journal-title":"Laryngoscope"},{"key":"10.1016\/j.anl.2021.01.016_bib0018","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.oraloncology.2005.05.008","article-title":"Histopathological prognosticators in oral and oropharyngeal squamous cell carcinoma","volume":"42","author":"Woolgar","year":"2006","journal-title":"Oral Oncol"},{"key":"10.1016\/j.anl.2021.01.016_bib0019","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/j.joms.2004.03.013","article-title":"Contralateral neck recurrence of squamous cell carcinoma of oral cavity and oropharynx","volume":"62","author":"Chow","year":"2004","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.anl.2021.01.016_bib0020","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.ijom.2007.01.008","article-title":"Contralateral lymph neck node metastasis of primary squamous cell carcinoma of the tongue: a retrospective analytic study of 203 patients","volume":"36","author":"Gonzalez-Garcia","year":"2007","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.anl.2021.01.016_bib0021","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/S0002-9610(05)80333-2","article-title":"Improved survival in the treatment of squamous carcinoma of the oral tongue","volume":"166","author":"Franceschi","year":"1993","journal-title":"Am J Surg"}],"container-title":["Auris Nasus Larynx"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0385814621000341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0385814621000341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T19:38:16Z","timestamp":1759952296000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0385814621000341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S0385814621000341"],"URL":"https:\/\/doi.org\/10.1016\/j.anl.2021.01.016","relation":{},"ISSN":["0385-8146"],"issn-type":[{"value":"0385-8146","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Contralateral lymph node recurrence rate and its prognostic factors in stage IVA-B well-lateralized oral cavity cancer","name":"articletitle","label":"Article Title"},{"value":"Auris Nasus Larynx","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anl.2021.01.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Oto-Rhino-Laryngological Society of Japan Inc. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}