{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T05:42:17Z","timestamp":1777873337866,"version":"3.51.4"},"reference-count":33,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,30]],"date-time":"2024-03-30T00:00:00Z","timestamp":1711756800000},"content-version":"am","delay-in-days":303,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100009619","name":"AMED","doi-asserted-by":"publisher","award":["18ck0106223h003"],"award-info":[{"award-number":["18ck0106223h003"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Auris Nasus Larynx"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.anl.2022.08.004","type":"journal-article","created":{"date-parts":[[2022,8,20]],"date-time":"2022-08-20T19:21:38Z","timestamp":1661023298000},"page":"358-364","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Expressions of NeuroD and GAP43 as diagnostic markers for olfactory neuroblastoma"],"prefix":"10.1016","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4127-3569","authenticated-orcid":false,"given":"Tatsuya","family":"Furukawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shun","family":"Tatehara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Teshima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotaka","family":"Shinomiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3654-5702","authenticated-orcid":false,"given":"Go","family":"Inokuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"Komatsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeo","family":"Hara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoh","family":"Zen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5461-4871","authenticated-orcid":false,"given":"Ken-ichi","family":"Nibu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"suppl 1","key":"10.1016\/j.anl.2022.08.004_bib0001","first-page":"E2259","article-title":"Neuroendocrine neoplasms of the sinonasal region","volume":"38","author":"Bell","year":"2016","journal-title":"Head Neck"},{"key":"10.1016\/j.anl.2022.08.004_bib0002","first-page":"410","article-title":"L'esthesioneuroepitheliomae olfactif","volume":"13","author":"Berger","year":"1924","journal-title":"Bull Asssoc Franc Etude Cancer"},{"key":"10.1016\/j.anl.2022.08.004_bib0003","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s11912-014-0423-z","article-title":"Prognosis and biology in esthesioneuroblastoma: the emerging role of Hyams grading system","volume":"17","author":"Saade","year":"2015","journal-title":"Curr Oncol Rep"},{"key":"10.1016\/j.anl.2022.08.004_bib0004","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S1470-2045(01)00558-7","article-title":"Esthesioneuroblastoma: a meta-analysis and review","volume":"2","author":"Dulguerov","year":"2001","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.anl.2022.08.004_bib0005","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1002\/hed.20920","article-title":"Esthesioneuroblastoma: the Princess Margaret Hospital experience","volume":"30","author":"Bachar","year":"2008","journal-title":"Head Neck"},{"key":"10.1016\/j.anl.2022.08.004_bib0006","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1002\/lary.26908","article-title":"Early Stage olfactory neuroblastoma and the impact of resecting dura and olfactory bulb","volume":"128","author":"Mays","year":"2018","journal-title":"Laryngoscope"},{"key":"10.1016\/j.anl.2022.08.004_bib0007","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s00701-017-3437-0","article-title":"Endoscopic endonasal resection of sinonasal\/anterior skull base malignancy (Kadish C esthesioneuroblastoma)","volume":"160","author":"Mehta","year":"2018","journal-title":"Acta Neurochir"},{"key":"10.1016\/j.anl.2022.08.004_bib0008","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1055\/s-0037-1606382","article-title":"Complications in salvage surgery for nasal and paranasal malignant tumors involving the skull base","volume":"79","author":"Teshima","year":"2018","journal-title":"J Neurol Surg B Skull Base"},{"key":"10.1016\/j.anl.2022.08.004_bib0009","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1002\/lary.27849","article-title":"Long-term quality of life after definitive treatment of sinonasal and nasopharyngeal malignancies","volume":"130","author":"Tyler","year":"2020","journal-title":"Laryngoscope"},{"key":"10.1016\/j.anl.2022.08.004_bib0010","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s12105-014-0547-3","article-title":"Prognostic utility of Hyams histological grading and Kadish-Morita staging systems for esthesioneuroblastoma outcomes","volume":"9","author":"Bell","year":"2015","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.anl.2022.08.004_bib0011","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1002\/hed.24822","article-title":"Outcomes for olfactory neuroblastoma treated with induction chemotherapy","volume":"39","author":"Su","year":"2017","journal-title":"Head Neck"},{"key":"10.1016\/j.anl.2022.08.004_bib0012","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1002\/hed.23327","article-title":"Optimization of long-term outcomes for patients with esthesioneuroblastoma","volume":"36","author":"Ow","year":"2014","journal-title":"Head Neck"},{"key":"10.1016\/j.anl.2022.08.004_bib0013","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1002\/1097-0142(197603)37:3<1571::AID-CNCR2820370347>3.0.CO;2-L","article-title":"Olfactory neuroblastoma. A clinical analysis of 17 cases","volume":"37","author":"Kadish","year":"1976","journal-title":"Cancer"},{"key":"10.1016\/j.anl.2022.08.004_bib0014","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1227\/00006123-199305000-00002","article-title":"Esthesioneuroblastoma: prognosis and management","volume":"32","author":"Morita","year":"1993","journal-title":"Neurosurgery"},{"key":"10.1016\/j.anl.2022.08.004_bib0015","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1288\/00005537-199208000-00001","article-title":"Esthesioneuroblastoma: the UCLA experience 1970-1990","volume":"102","author":"Dulguerov","year":"1992","journal-title":"Laryngoscope"},{"key":"10.1016\/j.anl.2022.08.004_bib0016","series-title":"Tumors of the upper respiratory tract and ear","first-page":"240","article-title":"Olfactory neuroblastoma","author":"Hyams","year":"1988"},{"key":"10.1016\/j.anl.2022.08.004_bib0017","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1055\/s-0032-1321512","article-title":"Long-term outcome of esthesioneuroblastoma: Hyams grade predicts patient survival","volume":"73","author":"Van Gompel","year":"2012","journal-title":"J Neurol Surg B Skull Base"},{"key":"10.1016\/j.anl.2022.08.004_bib0018","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jocn.2012.05.029","article-title":"The prognostic implications of Hyam's subtype for patients with Kadish stage C esthesioneuroblastoma","volume":"20","author":"Kaur","year":"2013","journal-title":"J Clin Neurosci"},{"issue":"2","key":"10.1016\/j.anl.2022.08.004_bib0019","doi-asserted-by":"crossref","first-page":"S149","DOI":"10.1055\/s-0034-1390014","article-title":"Esthesioneuroblastoma, neuroendocrine carcinoma, and sinonasal undifferentiated carcinoma: differentiation in diagnosis and treatment","volume":"18","author":"Su","year":"2014","journal-title":"Int Arch Otorhinolaryngol"},{"key":"10.1016\/j.anl.2022.08.004_bib0020","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.neures.2010.12.006","article-title":"Immunohistochemical detection of olfactory-specific sensory transduction proteins in olfactory neuroblastoma","volume":"69","author":"Matayoshi","year":"2011","journal-title":"Neurosci Res"},{"key":"10.1016\/j.anl.2022.08.004_bib0021","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/(SICI)1097-4695(199808)36:2<190::AID-NEU7>3.0.CO;2-X","article-title":"The neuronal stem cell of the olfactory epithelium","volume":"36","author":"Calof","year":"1998","journal-title":"J Neurobiol"},{"key":"10.1016\/j.anl.2022.08.004_bib0022","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s004410050063","article-title":"Olfactory neuron-specific expression of NeuroD in mouse and human nasal mucosa","volume":"298","author":"Nibu","year":"1999","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.anl.2022.08.004_bib0023","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1097\/00001756-200106130-00021","article-title":"Expression of NeuroD and TrkB in developing and aged mouse olfactory epithelium","volume":"12","author":"Nibu","year":"2001","journal-title":"Neuroreport"},{"key":"10.1016\/j.anl.2022.08.004_bib0024","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1080\/03655230410017742","article-title":"Quantitative analysis of expression of NeuroD, GAP43 and receptor tyrosine kinase B in developing mouse olfactory neuroepithelium","volume":"553","author":"Yasui","year":"2004","journal-title":"Acta Otolaryngol Suppl"},{"key":"10.1016\/j.anl.2022.08.004_bib0025","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0012-1606(80)90062-7","article-title":"Olfactory marker protein during ontogeny: immunohistochemical localization","volume":"74","author":"Farbman","year":"1980","journal-title":"Dev Biol"},{"key":"10.1016\/j.anl.2022.08.004_bib0026","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.anndiagpath.2015.03.009","article-title":"Achaete-scute homolog 1 expression closely correlates with endocrine phenotype and degree of differentiation in sinonasal neuroendocrine tumors","volume":"19","author":"Taggart","year":"2015","journal-title":"Ann Diagn Pathol"},{"key":"10.1016\/j.anl.2022.08.004_bib0027","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1309\/QD0K9Q1JBH6B5GQQ","article-title":"Human achaete-scute homologue (hASH1) mRNA level as a diagnostic marker to distinguish esthesioneuroblastoma from poorly differentiated tumors arising in the sinonasal tract","volume":"122","author":"Mhawech","year":"2004","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.anl.2022.08.004_bib0028","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1097\/WNR.0000000000001125","article-title":"Effect of intranasal administration of neurotrophic factors on regeneration of chemically degenerated olfactory epithelium in aging mice","volume":"29","author":"Fukuda","year":"2018","journal-title":"Neuroreport"},{"key":"10.1016\/j.anl.2022.08.004_bib0029","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/modpathol.2013.128","article-title":"Growth-associated protein 43 in differentiating peripheral nerve sheath tumors from other non-neural spindle cell neoplasms","volume":"27","author":"Chen","year":"2014","journal-title":"Mod Pathol"},{"key":"10.1016\/j.anl.2022.08.004_bib0030","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/BF01054767","article-title":"Expression of the human achaete-scute 1 gene in olfactory neuroblastoma (esthesioneuroblastoma)","volume":"26","author":"Carney","year":"1995","journal-title":"J Neurooncol"},{"key":"10.1016\/j.anl.2022.08.004_bib0031","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.4238\/2013.September.10.4","article-title":"Odorant receptor genes are expressed in olfactory neuroblastoma","volume":"12","author":"Gonzalez-Kristeller","year":"2013","journal-title":"Genet Mol Res"},{"key":"10.1016\/j.anl.2022.08.004_bib0032","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/0306-4522(96)00143-1","article-title":"Induction of differentiation of human olfactory neuroblastoma cells into odorant-responsive cells","volume":"74","author":"Gomez","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.anl.2022.08.004_bib0033","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1006\/bbrc.2000.3899","article-title":"bFGF induces differentiation and death of olfactory neuroblastoma cells","volume":"279","author":"Nibu","year":"2000","journal-title":"Biochem Biophys Res Commun"}],"container-title":["Auris Nasus Larynx"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0385814622001973?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0385814622001973?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:54:24Z","timestamp":1777571664000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0385814622001973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S0385814622001973"],"URL":"https:\/\/doi.org\/10.1016\/j.anl.2022.08.004","relation":{},"ISSN":["0385-8146"],"issn-type":[{"value":"0385-8146","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expressions of NeuroD and GAP43 as diagnostic markers for olfactory neuroblastoma","name":"articletitle","label":"Article Title"},{"value":"Auris Nasus Larynx","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anl.2022.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Japanese Society of Otorhinolaryngology-Head and Neck Surgery, Inc. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}