{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T08:51:12Z","timestamp":1780390272686,"version":"3.54.1"},"reference-count":47,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Auris Nasus Larynx"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.anl.2025.01.006","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T17:23:02Z","timestamp":1737480182000},"page":"76-83","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association of olfactory training with olfactory bulb morphology in adults with post-viral long-lasting olfactory dysfunction: A COVID-19 related prospective study"],"prefix":"10.1016","volume":"52","author":[{"given":"Mustafa","family":"Baran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6803-5467","authenticated-orcid":false,"given":"Mahmut Tayyar","family":"Kalcioglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9022-921X","authenticated-orcid":false,"given":"Ahmet","family":"Mutlu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basak","family":"Atalay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7063-7371","authenticated-orcid":false,"given":"Mahmut Bilal","family":"Dogan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guler","family":"Ozturk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.anl.2025.01.006_bib0001","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1002\/lary.24340","article-title":"Olfactory training is helpful in postinfectious olfactory loss: a randomized, controlled, multicenter study","volume":"124","author":"Damm","year":"2014","journal-title":"Laryngoscope"},{"key":"10.1016\/j.anl.2025.01.006_bib0002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4193\/Rhin22.483","article-title":"Position paper on olfactory dysfunction: 2023","volume":"61","author":"Whitcroft","year":"2023","journal-title":"Rhinology"},{"key":"10.1016\/j.anl.2025.01.006_bib0003","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4193\/Rhino16.248","article-title":"Position paper on olfactory dysfunction","volume":"54","author":"Hummel","year":"2017","journal-title":"Rhinol Suppl"},{"key":"10.1016\/j.anl.2025.01.006_bib0004","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.jad.2022.12.049","article-title":"Olfactory-related quality of life impacts psychological distress in people with COVID-19: The affective implications of olfactory dysfunctions","volume":"323","author":"Bochicchio","year":"2023","journal-title":"J Affect Disord"},{"key":"10.1016\/j.anl.2025.01.006_bib0005","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1038\/d41586-020-00694-1","article-title":"Keep up with the latest coronavirus research","volume":"579","author":"Chen","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.anl.2025.01.006_bib0006","doi-asserted-by":"crossref","first-page":"5475","DOI":"10.3390\/ijms21155475","article-title":"SARS-CoV-2 and the nervous system: from clinical features to molecular mechanisms","volume":"21","author":"Pennisi","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.anl.2025.01.006_bib0007","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/j.mayocp.2020.05.030","article-title":"Smell and taste dysfunction in patients With COVID-19: A systematic review and meta-analysis","volume":"95","author":"Agyeman","year":"2020","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.anl.2025.01.006_bib0008","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1002\/lary.20101","article-title":"Effects of olfactory training in patients with olfactory loss","volume":"119","author":"Hummel","year":"2009","journal-title":"Laryngoscope"},{"key":"10.1016\/j.anl.2025.01.006_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2022.104853","article-title":"Olfactory training - Thirteen years of research reviewed","volume":"141","author":"Pieniak","year":"2022","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.anl.2025.01.006_bib0010","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1177\/1073858404267048","article-title":"Plasticity in the olfactory system: lessons for the neurobiology of memory","volume":"10","author":"Wilson","year":"2004","journal-title":"Neuroscientist"},{"key":"10.1016\/j.anl.2025.01.006_bib0011","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/s41593-020-0587-9","article-title":"Single-cell analysis of olfactory neurogenesis and differentiation in adult humans","volume":"23","author":"Durante","year":"2020","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.anl.2025.01.006_bib0012","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.pneurobio.2009.07.003","article-title":"Adult neurogenesis and the olfactory system","volume":"89","author":"Whitman","year":"2009","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.anl.2025.01.006_bib0013","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/(SICI)1097-4695(199605)30:1<123::AID-NEU11>3.0.CO;2-N","article-title":"Functional organization of olfactory system","volume":"30","author":"Shipley","year":"1996","journal-title":"J Neurobiol"},{"key":"10.1016\/j.anl.2025.01.006_bib0014","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/0306-4522(95)00309-7","article-title":"Neurotransmitter release in the accessory olfactory bulb during and after the formation of an olfactory memory in mice","volume":"69","author":"Brennan","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/j.anl.2025.01.006_bib0015","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/0165-0173(94)90007-8","article-title":"Unilateral naris closure and olfactory system development","volume":"19","author":"Brunjes","year":"1994","journal-title":"Brain Res Brain Res Rev"},{"key":"10.1016\/j.anl.2025.01.006_bib0016","doi-asserted-by":"crossref","first-page":"5932","DOI":"10.1016\/j.cell.2021.10.027","article-title":"Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb","volume":"184","author":"Khan","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.anl.2025.01.006_bib0017","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1007\/s10072-020-04590-4","article-title":"Frequency and outcome of olfactory impairment and sinonasal involvement in hospitalized patients with COVID-19","volume":"41","author":"Jalessi","year":"2020","journal-title":"Neurol Sci"},{"key":"10.1016\/j.anl.2025.01.006_bib0018","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.acra.2020.04.002","article-title":"Olfactory bulb magnetic resonance imaging in SARS-CoV-2-induced anosmia: the first report","volume":"27","author":"Galougahi","year":"2020","journal-title":"Acad Radiol"},{"key":"10.1016\/j.anl.2025.01.006_bib0019","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1001\/jamaoto.2020.0832","article-title":"Sudden and complete olfactory loss of function as a possible symptom of COVID-19","volume":"146","author":"Eliezer","year":"2020","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.anl.2025.01.006_bib0020","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1097\/01.mlg.0000217533.60311.e7","article-title":"Retronasal and orthonasal olfactory function in relation to olfactory bulb volume in patients with posttraumatic loss of smell","volume":"116","author":"Rombaux","year":"2006","journal-title":"Laryngoscope"},{"key":"10.1016\/j.anl.2025.01.006_bib0021","doi-asserted-by":"crossref","first-page":"532","DOI":"10.3174\/ajnr.A5491","article-title":"MR imaging-based evaluations of olfactory bulb atrophy in patients with olfactory dysfunction","volume":"39","author":"Chung","year":"2018","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.anl.2025.01.006_bib0022","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.neuroimage.2008.05.004","article-title":"Correlation between olfactory bulb volume and olfactory function","volume":"42","author":"Buschhuter","year":"2008","journal-title":"NeuroImage"},{"key":"10.1016\/j.anl.2025.01.006_bib0023","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1097\/00001756-200504040-00011","article-title":"Reduced olfactory bulb volume in post-traumatic and post-infectious olfactory dysfunction","volume":"16","author":"Mueller","year":"2005","journal-title":"Neuroreport"},{"key":"10.1016\/j.anl.2025.01.006_bib0024","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1097\/01.MLG.0000195291.36641.1E","article-title":"Olfactory function and olfactory bulb volume in patients with postinfectious olfactory loss","volume":"116","author":"Rombaux","year":"2006","journal-title":"Laryngoscope"},{"key":"10.1016\/j.anl.2025.01.006_bib0025","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s40463-020-00423-8","article-title":"Early recovery following new onset anosmia during the COVID-19 pandemic - an observational cohort study","volume":"49","author":"Hopkins","year":"2020","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.anl.2025.01.006_bib0026","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1001\/jamaoto.2020.1379","article-title":"Evolution of altered sense of smell or taste in patients with mildly symptomatic COVID-19","volume":"146","author":"Boscolo-Rizzo","year":"2020","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.anl.2025.01.006_bib0027","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1007\/s00405-018-5248-1","article-title":"Updated Sniffin' Sticks normative data based on an extended sample of 9139 subjects","volume":"276","author":"Oleszkiewicz","year":"2019","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.anl.2025.01.006_bib0028","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1001\/jama.2020.8391","article-title":"Olfactory dysfunction in COVID-19: diagnosis and management","volume":"323","author":"Whitcroft","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.anl.2025.01.006_bib0029","first-page":"3","article-title":"Olfactory bulb volume in the clinical assessment of olfactory dysfunction","volume":"47","author":"Rombaux","year":"2009","journal-title":"Rhinology"},{"key":"10.1016\/j.anl.2025.01.006_bib0030","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1749-6632.1998.tb10624.x","article-title":"Olfactory bulb and tract and temporal lobe volumes. Normative data across decades","volume":"855","author":"Yousem","year":"1998","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.anl.2025.01.006_bib0031","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.acra.2020.10.006","article-title":"Olfactory bulb MRI and paranasal sinus CT findings in persistent COVID-19 anosmia","volume":"28","author":"Kandemirli","year":"2021","journal-title":"Acad Radiol"},{"key":"10.1016\/j.anl.2025.01.006_bib0032","first-page":"1703","article-title":"Anosmia in COVID-19 associated with injury to the olfactory bulbs evident on MRI","volume":"41","author":"Arag\u00e3o","year":"2020","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.anl.2025.01.006_bib0033","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.mri.2012.05.001","article-title":"3D slicer as an image computing platform for the quantitative imaging network","volume":"30","author":"Fedorov","year":"2012","journal-title":"Magn Reson Imaging"},{"key":"10.1016\/j.anl.2025.01.006_bib0034","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.ejrad.2009.05.065","article-title":"Imaging the olfactory tract (cranial nerve #1)","volume":"74","author":"Duprez","year":"2010","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.anl.2025.01.006_bib0035","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.3174\/ajnr.A6751","article-title":"Olfactory bulb signal abnormality in patients with COVID-19 who present with neurologic symptoms","volume":"41","author":"Strauss","year":"2020","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.anl.2025.01.006_bib0036","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1097\/00001756-200504040-00011","article-title":"Reduced olfactory bulb volume in post-traumatic and post-infectious olfactory dysfunction","volume":"16","author":"Mueller","year":"2005","journal-title":"Neuroreport"},{"key":"10.1016\/j.anl.2025.01.006_bib0037","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1126\/science.1136281","article-title":"Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension","volume":"315","author":"Curtis","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.anl.2025.01.006_bib0038","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1177\/1073858404263460","article-title":"Inhibitory interneurons in the olfactory bulb: from development to function","volume":"10","author":"Lledo","year":"2004","journal-title":"Neuroscientist"},{"key":"10.1016\/j.anl.2025.01.006_bib0039","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1001\/jamaoto.2019.1728","article-title":"Clinical diagnosis and current management strategies for olfactory dysfunction: a review","volume":"145","author":"Whitcroft","year":"2019","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.anl.2025.01.006_bib0040","doi-asserted-by":"crossref","first-page":"170","DOI":"10.4193\/Rhino15.264","article-title":"Long term effects of olfactory training in patients with post-infectious olfactory loss","volume":"54","author":"Konstantinidis","year":"2016","journal-title":"Rhinology"},{"key":"10.1016\/j.anl.2025.01.006_bib0041","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1002\/alr.22624","article-title":"Treatment of post-viral olfactory dysfunction: an evidence-based review with recommendations","volume":"10","author":"Hura","year":"2020","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.anl.2025.01.006_bib0042","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/1440-1681.13626","article-title":"Olfactory training for olfactory dysfunction in COVID-19: A promising mitigation amidst looming neurocognitive sequelae of the pandemic","volume":"49","author":"Ojha","year":"2022","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.anl.2025.01.006_bib0043","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0259321","article-title":"Olfactory recovery following infection with COVID-19: A systematic review","volume":"16","author":"Jafar","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.anl.2025.01.006_bib0044","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/alr.22929","article-title":"International consensus statement on allergy and rhinology: Olfaction","volume":"12","author":"Patel","year":"2022","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.anl.2025.01.006_bib0045","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1001\/jama.2020.8391","article-title":"Olfactory dysfunction in COVID-19: diagnosis and management","volume":"323","author":"Whitcroft","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.anl.2025.01.006_bib0046","doi-asserted-by":"crossref","first-page":"3113","DOI":"10.1007\/s00405-020-06520-8","article-title":"Efficacy and safety of oral corticosteroids and olfactory training in the management of COVID-19-related loss of smell","volume":"278","author":"Le Bon","year":"2021","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.anl.2025.01.006_bib0047","doi-asserted-by":"crossref","first-page":"e29583","DOI":"10.2196\/29583","article-title":"Olfactory training and visual stimulation assisted by a web application for patients with persistent olfactory dysfunction after SARS-CoV-2 infection: observational study","volume":"23","author":"Denis","year":"2021","journal-title":"J Med Internet Res"}],"container-title":["Auris Nasus Larynx"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0385814625000069?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0385814625000069?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T23:11:58Z","timestamp":1739833918000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0385814625000069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S0385814625000069"],"URL":"https:\/\/doi.org\/10.1016\/j.anl.2025.01.006","relation":{},"ISSN":["0385-8146"],"issn-type":[{"value":"0385-8146","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of olfactory training with olfactory bulb morphology in adults with post-viral long-lasting olfactory dysfunction: A COVID-19 related prospective study","name":"articletitle","label":"Article Title"},{"value":"Auris Nasus Larynx","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anl.2025.01.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Japanese Society of Otorhinolaryngology-Head and Neck Surgery, Inc. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}