{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T23:00:36Z","timestamp":1789426836371,"version":"build-2803163510"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","annalspathology.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Diagnostic Pathology"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.anndiagpath.2016.04.007","type":"journal-article","created":{"date-parts":[[2016,4,30]],"date-time":"2016-04-30T06:46:24Z","timestamp":1461998784000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["c-Met expression and MET amplification in malignant pleural mesothelioma"],"prefix":"10.1016","volume":"23","author":[{"given":"Melanie C.","family":"Bois","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron S.","family":"Mansfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Sukov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah M.","family":"Jenkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin C.","family":"Moser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher A.","family":"Sattler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carin Y.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian R.","family":"Molina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Peikert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja C.","family":"Roden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0005","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.ejcts.2007.09.044","article-title":"Malignant pleural mesothelioma: clinicopathologic and survival characteristics in a consecutive series of 394 patients","volume":"33","author":"Borasio","year":"2008","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0010","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1097\/JTO.0b013e31815608d9","article-title":"Prognostic factors in the treatment of malignant pleural mesothelioma at a large tertiary referral center","volume":"2","author":"Flores","year":"2007","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0015","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.lungcan.2014.08.017","article-title":"Systematic review of response rates of sarcomatoid malignant pleural mesotheliomas in clinical trials","volume":"86","author":"Mansfield","year":"2014","journal-title":"Lung Cancer"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0020","first-page":"5242","article-title":"Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma","volume":"62","author":"Janne","year":"2002","journal-title":"Cancer Res"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0025","doi-asserted-by":"crossref","first-page":"3267","DOI":"10.1200\/JCO.2001.19.13.3267","article-title":"Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies","volume":"19","author":"Hidalgo","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0030","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1097\/JTO.0b013e3182417da5","article-title":"Plasma cell membrane localization of c-MET predicts longer survival in patients with malignant mesothelioma: a series of 157 cases from the MESOPATH group","volume":"7","author":"Levallet","year":"2012","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0035","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1158\/0008-5472.CAN-04-4567","article-title":"Functional analysis of c-met\/hepatocyte growth factor pathway in malignant pleural mesothelioma","volume":"66","author":"Jagadeeswaran","year":"2006","journal-title":"Cancer Res"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0040","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s004320050171","article-title":"Hepatocyte growth factor\/scatter factor and its receptor c-met are overexpressed and associated with an increased microvessel density in malignant pleural mesothelioma","volume":"124","author":"Tolnay","year":"1998","journal-title":"J Cancer Res Clin Oncol"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0045","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1046\/j.1365-2559.2000.00888.x","article-title":"Immunoreactivity for cadherins, HGF\/SF, met, and erbB-2 in pleural malignant mesotheliomas","volume":"36","author":"Thirkettle","year":"2000","journal-title":"Histopathology"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0050","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.lungcan.2008.06.011","article-title":"MET as a target for treatment of chest tumors","volume":"63","author":"Cipriani","year":"2009","journal-title":"Lung Cancer"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.canlet.2004.09.044","article-title":"C-met as a target for human cancer and characterization of inhibitors for therapeutic intervention","volume":"225","author":"Christensen","year":"2005","journal-title":"Cancer Lett"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0060","doi-asserted-by":"crossref","first-page":"8122","DOI":"10.1158\/1078-0432.CCR-05-1191","article-title":"Inhibition of the met receptor in mesothelioma","volume":"11","author":"Mukohara","year":"2005","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0065","first-page":"3539","article-title":"Microarray analysis and RNA silencing link fra-1 to cd44 and c-met expression in mesothelioma","volume":"63","author":"Ramos-Nino","year":"2003","journal-title":"Cancer Res"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0070","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1097\/JTO.0b013e318215a07d","article-title":"Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy","volume":"6","author":"Brevet","year":"2011","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0075","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1158\/0008-5472.CAN-06-3495","article-title":"Lung cancer cell lines harboring MET gene amplification are dependent on met for growth and survival","volume":"67","author":"Lutterbach","year":"2007","journal-title":"Cancer Res"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0080","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1093\/annonc\/mdn635","article-title":"MET increased gene copy number and primary resistance to gefitinib therapy in non\u2013small-cell lung cancer patients","volume":"20","author":"Cappuzzo","year":"2009","journal-title":"Ann Oncol"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0085","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1016\/j.jtho.2015.10.019","article-title":"MET Gene status in malignant mesothelioma using fluorescent in situ hybridization","volume":"11","author":"Varesano","year":"2016","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0090","series-title":"WHO classification of tumours of the lung, pleura, thymus and heart","year":"2015"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0095","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/JTO.0b013e318240ca0d","article-title":"Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer","volume":"7","author":"Dziadziuszko","year":"2012","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0100","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/modpathol.2011.144","article-title":"Epithelial-mesenchymal transition in malignant mesothelioma","volume":"25","author":"Fassina","year":"2012","journal-title":"Mod Pathol"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0105","doi-asserted-by":"crossref","first-page":"16215","DOI":"10.18632\/oncotarget.3976","article-title":"MET expression and copy number heterogeneity in nonsquamous non\u2013small cell lung cancer (nsNSCLC)","volume":"6","author":"Casadevall","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0110","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1159\/000079496","article-title":"Expression of S100A4 and MET: potential predictors for metastasis and survival in early-stage breast cancer","volume":"66","author":"Lee","year":"2004","journal-title":"Oncology"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0115","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1159\/000011985","article-title":"Clinical significance of c-Met oncogene alterations in human colorectal cancer","volume":"56","author":"Umeki","year":"1999","journal-title":"Oncology"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0120","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0133859","article-title":"Comprehensive molecular analysis of NSCLC; clinicopathological associations","volume":"10","author":"Chatziandreou","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0125","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.lungcan.2014.11.018","article-title":"Parallel screening for ALK, MET and ROS1 alterations in non-small cell lung cancer with implications for daily routine testing","volume":"87","author":"Jurmeister","year":"2015","journal-title":"Lung Cancer"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0130","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/JTO.0b013e3181ce3d1d","article-title":"High MET gene copy number leads to shorter survival in patients with non\u2013small cell lung cancer","volume":"5","author":"Go","year":"2010","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0135","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1093\/carcin\/bgt166","article-title":"Molecular pathogenesis of malignant mesothelioma","volume":"34","author":"Sekido","year":"2013","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0140","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0165-4608(89)90105-2","article-title":"Specificity of asbestos-induced chromosomal aberrations in short-term cultured human mesothelial cells","volume":"41","author":"Olofsson","year":"1989","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0145","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/cncr.11398","article-title":"Detection of numerical aberrations of chromosomes 7 and 9 in cytologic specimens of pleural malignant mesothelioma","volume":"99","author":"Shin","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0150","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1038\/bjc.1989.326","article-title":"Chromosomal abnormalities and their correlations with asbestos exposure and survival in patients with mesothelioma","volume":"60","author":"Tiainen","year":"1989","journal-title":"Br J Cancer"},{"key":"10.1016\/j.anndiagpath.2016.04.007_bb0155","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1378\/chest.09-1951","article-title":"Fluorescence in situ hybridization in the definitive diagnosis of malignant mesothelioma in effusion cytology","volume":"138","author":"Savic","year":"2010","journal-title":"Chest"}],"container-title":["Annals of Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913416300740?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913416300740?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T18:20:17Z","timestamp":1536776417000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1092913416300740"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":31,"alternative-id":["S1092913416300740"],"URL":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2016.04.007","relation":{},"ISSN":["1092-9134"],"issn-type":[{"value":"1092-9134","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"c-Met expression and MET amplification in malignant pleural mesothelioma","name":"articletitle","label":"Article Title"},{"value":"Annals of Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2016.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}