{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T17:21:04Z","timestamp":1778520064915,"version":"3.51.4"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Diagnostic Pathology"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.anndiagpath.2020.151599","type":"journal-article","created":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T11:40:15Z","timestamp":1598269215000},"page":"151599","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Fumarate hydratase-deficient renal cell carcinoma: A clinicopathological study of seven cases including hereditary and sporadic forms"],"prefix":"10.1016","volume":"49","author":[{"given":"Naoto","family":"Kuroda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miho","family":"Tsutsui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuko","family":"Iguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emi","family":"Nobuoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Uehara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuta","family":"Sonobe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiko","family":"Morinaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinsuke","family":"Shibuya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wakako","family":"Oda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Yanai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiaki","family":"Kawada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Karashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Yamasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoji","family":"Nagashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.anndiagpath.2020.151599_bb0005","doi-asserted-by":"crossref","first-page":"3387","DOI":"10.1073\/pnas.051633798","article-title":"Inherited susceptibility to uterine leiomyomas and renal cell cancer","volume":"98","author":"Launonen","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0010","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1038\/ng849","article-title":"Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer","volume":"30","author":"Tomlinson","year":"2002","journal-title":"Nat. Genet."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0015","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1086\/376435","article-title":"Mutation in the fumarate hydratase gene case hereditary leiomyomatosis and renal cell cancer in families in North America","volume":"73","author":"Toro","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0020","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1097\/PAS.0000000000000617","article-title":"Fumarate hydratase-deficient renal cell carcinoma is strongly correlated with fumarate hydratase mutation and hereditary leiomyomatosis and renal cell carcinoma syndrome","volume":"40","author":"Trpkov","year":"2016","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0025","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1097\/PAS.0b013e31804375b8","article-title":"The morphologic spectrum of kidney tumors in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome","volume":"31","author":"Merino","year":"2007","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0030","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1097\/PAS.0000000000000163","article-title":"Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cancer recognition of the syndrome by pathologic features and the utility of detecting aberrant succination by immunohistochemistry","volume":"38","author":"Chen","year":"2014","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0035","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1097\/PAS.0000000000000127","article-title":"Hereditary leiomyomatosis and renal cell carcinoma (HLRCC). A rapid of autopsy report of metastatic renal cell carcinoma","volume":"38","author":"Udagar","year":"2014","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0040","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/PAI.0000000000000213","volume":"24","author":"Ulamec","year":"2016","journal-title":"Appl. Immunohistochem. Mol. Morphol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0045","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1097\/PAS.0000000000001000","article-title":"Reappraisal of morphologic differences between renal medullary carcinoma, collecting duct carcinoma, and fumarate hydratase-deficient renal cell carcinoma","volume":"42","author":"Ohe","year":"2018","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0050","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/his.13183","article-title":"A distinctive, low-grade oncocytic fumarate hydratase-deficient renal cell carcinoma, morphologically reminiscent of succinate dehydrogenase-deficient renal cell carcinoma","volume":"71","author":"Smith","year":"2017","journal-title":"Histopathology"},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0055","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1097\/PAS.0b013e318299f2d1","article-title":"International Society of Urologic Pathology (ISUP) Vancouver classification of renal neoplasia","volume":"37","author":"Srigley","year":"2013","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0060","series-title":"World Health Organization classification of tumours of urinary system and male genital organs","author":"Moch","year":"2016"},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0065","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1097\/00000478-200306000-00005","article-title":"Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: a sensitive and specific immunohistochemical assay","volume":"27","author":"Argani","year":"2003","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0070","doi-asserted-by":"crossref","first-page":"e285","DOI":"10.1111\/1346-8138.14855","article-title":"Hereditary leiomyomatosis and renal cell cancer syndrome in which skin biopsy enabled diagnosis","volume":"46","author":"Matsuda","year":"2019","journal-title":"J. Dermatol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0075","first-page":"4554","article-title":"Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families","volume":"62","author":"Kiuru","year":"2002","journal-title":"Cancer Res."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0080","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1097\/PAS.0b013e3181d90370","article-title":"Renal epithelioid angiomyolipoma with atypia: a series of 40 cases with emphasis on clinicopathologic prognostic indicators of malignancy","volume":"34","author":"Brimo","year":"2010","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0085","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1016\/S0002-9440(10)64680-9","article-title":"A distinctive pediatric renal neoplasm characterized by epithelioid morphology, basement membrane production, focal HMB45 immunoreactivity, and t(6;11)(p21.1;q12) chromosome translocation","volume":"158","author":"Argani","year":"2001","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0090","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1097\/MOU.0000000000000094","article-title":"Nephron-sparing surgery for multifocal and hereditary renal tumors","volume":"24","author":"Metwalli","year":"2014","journal-title":"Curr. Opin. Urol."},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0095","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s10689-014-9735-2","article-title":"Hereditary leiomyomatosis and renal cell cancer (HLRCC). Renal cancer risk, surveillance and treatment","volume":"13","author":"Menko","year":"2014","journal-title":"Familial Cancer"},{"key":"10.1016\/j.anndiagpath.2020.151599_bb0100","doi-asserted-by":"crossref","first-page":"284","DOI":"10.5114\/pjp.2017.73920","article-title":"Review of hereditary leiomyomatosis renal cell carcinoma with focus on clinical and pathobiological aspects of renal tumors","volume":"68","author":"Kuroda","year":"2017","journal-title":"Pol. J. Pathol."}],"container-title":["Annals of Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913420301428?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913420301428?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T20:33:20Z","timestamp":1761078800000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1092913420301428"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":20,"alternative-id":["S1092913420301428"],"URL":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2020.151599","relation":{},"ISSN":["1092-9134"],"issn-type":[{"value":"1092-9134","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fumarate hydratase-deficient renal cell carcinoma: A clinicopathological study of seven cases including hereditary and sporadic forms","name":"articletitle","label":"Article Title"},{"value":"Annals of Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2020.151599","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"151599"}}