{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T22:43:08Z","timestamp":1772836988619,"version":"3.50.1"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81902969"],"award-info":[{"award-number":["81902969"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Scientific Research Project of Jiangsu Commission of Health","award":["H2018033"],"award-info":[{"award-number":["H2018033"]}]},{"name":"Jiangsu Province Key Clinical SpecialityVactional School","award":["5201011305000606"],"award-info":[{"award-number":["5201011305000606"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Diagnostic Pathology"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.anndiagpath.2020.151648","type":"journal-article","created":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T02:13:50Z","timestamp":1604974430000},"page":"151648","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Identification of vital genes and pathways associated with mucosal melanoma in Chinese"],"prefix":"10.1016","volume":"50","author":[{"given":"Mingzhan","family":"Du","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongmei","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingchuan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.anndiagpath.2020.151648_bb0005","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/1471-2407-11-85","article-title":"Clinical presentation, histology, and prognoses of malignant melanoma in ethnic Chinese: a study of 522 consecutive cases","volume":"11","author":"Chi","year":"2011","journal-title":"BMC Cancer"},{"issue":"5","key":"10.1016\/j.anndiagpath.2020.151648_bb0010","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/j.jaad.2006.06.017","article-title":"Primary mucosal melanoma","volume":"56","author":"Patrick","year":"2007","journal-title":"J Am Acad Dermatol"},{"issue":"11","key":"10.1016\/j.anndiagpath.2020.151648_bb0015","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.2967\/jnumed.119.228312","article-title":"Metabolic biomarker-based BRAFV600 mutation association and prediction in melanoma","volume":"60","author":"Saadani","year":"2019","journal-title":"J Nucl Med"},{"issue":"1","key":"10.1016\/j.anndiagpath.2020.151648_bb0020","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1186\/s12967-017-1344-z","article-title":"Identification of coexistence of BRAF V600E mutation and EZH2 gain specifically in melanoma as a promising target for combination therapy","volume":"15","author":"Yu","year":"2017","journal-title":"J Transl Med"},{"issue":"5","key":"10.1016\/j.anndiagpath.2020.151648_bb0025","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1002\/ijc.31780","article-title":"TERT promoter mutation subtypes and survival in stage I and II melanoma patients","volume":"144","author":"Andr\u00e9s-Lencina","year":"2019","journal-title":"Int J Cancer"},{"issue":"10","key":"10.1016\/j.anndiagpath.2020.151648_bb0030","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1001\/jamaophthalmol.2018.2986","article-title":"Association of uveal melanoma metastatic rate with stochastic mutation rate and type of mutation","volume":"136","author":"Szalai","year":"2018","journal-title":"JAMA Ophthalmol"},{"issue":"2","key":"10.1016\/j.anndiagpath.2020.151648_bb0035","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s00432-017-2550-z","article-title":"Analysis of TSC1 mutation spectrum in mucosal melanoma","volume":"144","author":"Ma","year":"2018","journal-title":"J Cancer Res Clin Oncol"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0040","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.ebiom.2018.05.019","article-title":"TP53 mutation as potential negative predictor for response of anti-CTLA-4 therapy in metastatic melanoma","volume":"32","author":"Xiao","year":"2018","journal-title":"EBioMedicine"},{"issue":"7","key":"10.1016\/j.anndiagpath.2020.151648_bb0045","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1016\/j.cell.2015.05.044","article-title":"Genomic classification of cutaneous melanoma","volume":"161","author":"Akbani","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0050","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/nature22071","article-title":"Whole-genome landscapes of major melanoma subtypes","volume":"545","author":"Hayward","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0055","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1158\/1541-7786.MCR-16-0494","article-title":"Epigenetic regulation of ZBTB18 promotes glioblastoma progression","volume":"15","author":"Fedele","year":"2017","journal-title":"Mol Cancer Res"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0060","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1007\/s11596-016-1674-8","article-title":"miR-206 inhibits renal cell cancer growth by targeting GAK","volume":"36","author":"Wei","year":"2016","journal-title":"J Huazhong Univ Sci Technolog Med Sci"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0065","doi-asserted-by":"crossref","first-page":"3041","DOI":"10.1158\/0008-5472.CAN-17-3776","article-title":"Kir2.1 interaction with Stk38 promotes invasion and metastasis of human gastric cancer by enhancing MEKK2-MEK1\/2-ERK1\/2 signaling","volume":"78","author":"Ji","year":"2018","journal-title":"Cancer Res"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0070","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1007\/s10620-017-4732-6","article-title":"UBR5 contributes to colorectal cancer progression by destabilizing the tumor suppressor ECRG4","volume":"62","author":"Wang","year":"2017","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0075","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1016\/j.bbrc.2016.08.170","article-title":"The E3 ligase UBR5 regulates gastric cancer cell growth by destabilizing the tumor suppressor GKN1","volume":"478","author":"Yang","year":"2016","journal-title":"Biochem Biophys Res Commun"},{"issue":"6","key":"10.1016\/j.anndiagpath.2020.151648_bb0080","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1177\/0962280209351908","article-title":"Gene set enrichment analysis made simple","volume":"18","author":"Irizarry","year":"2009","journal-title":"Stat Methods Med Res"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0085","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1097\/AOG.0000000000000171","article-title":"Human papillomavirus genotype prevalence in invasive vaginal cancer from a registry-based population","volume":"123","author":"Sinno","year":"2014","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0090","doi-asserted-by":"crossref","first-page":"e420","DOI":"10.1111\/codi.12257","article-title":"Human papillomavirus infection and colorectal cancer risk: a meta-analysis","volume":"15","author":"Damin","year":"2013","journal-title":"Colorectal Dis"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0095","doi-asserted-by":"crossref","first-page":"3163","DOI":"10.1038\/s41467-019-11107-x","article-title":"Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets","volume":"10","author":"Newell","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0100","doi-asserted-by":"crossref","first-page":"22823","DOI":"10.1074\/jbc.M701758200","article-title":"Differentially spliced isoforms of FAT1 are asymmetrically distributed within migrating cells","volume":"282","author":"Braun","year":"2007","journal-title":"J Biol Chem"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0105","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/bjc.2016.145","article-title":"FAT1: a potential target for monoclonal antibody therapy in colon cancer","volume":"115","author":"Pileri","year":"2016","journal-title":"Br J Cancer"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0110","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/ng.2538","article-title":"Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation","volume":"45","author":"Morris","year":"2013","journal-title":"Nat Genet"},{"key":"10.1016\/j.anndiagpath.2020.151648_bb0115","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s12038-011-9172-4","article-title":"Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K\/Akt\/mTOR signalling pathway","volume":"37","author":"Wang","year":"2012","journal-title":"J Biosci"}],"container-title":["Annals of Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913420301945?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913420301945?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T20:32:11Z","timestamp":1761078731000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1092913420301945"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":23,"alternative-id":["S1092913420301945"],"URL":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2020.151648","relation":{},"ISSN":["1092-9134"],"issn-type":[{"value":"1092-9134","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of vital genes and pathways associated with mucosal melanoma in Chinese","name":"articletitle","label":"Article Title"},{"value":"Annals of Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2020.151648","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"151648"}}