{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T21:55:19Z","timestamp":1777586119473,"version":"3.51.4"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Diagnostic Pathology"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.anndiagpath.2021.151727","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T12:45:32Z","timestamp":1614602732000},"page":"151727","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Comparative study of immunohistochemical expression of ERG and MAGI2 in prostatic carcinoma"],"prefix":"10.1016","volume":"52","author":[{"given":"Marwa Mohammed","family":"Dawoud","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayam Abdel-Samie","family":"Aiad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaa Mohamed Nasser Hamed","family":"Bahbah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Ibrahim","family":"Shaban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.anndiagpath.2021.151727_bb0005","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/bju.13862","article-title":"Prostate cancer family history and eligibility for active surveillance: a systematic review of the literature","volume":"120","author":"Telang","year":"2017","journal-title":"BJU Int"},{"key":"10.1016\/j.anndiagpath.2021.151727_bb0010","first-page":"74","article-title":"Immunohistochemical expression of ERG and P63 in some prostatic lesions","volume":"4","author":"Ibrahim","year":"2019","journal-title":"Egyptian Journal of Hospital Medicine"},{"issue":"9","key":"10.1016\/j.anndiagpath.2021.151727_bb0015","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1097\/00000478-200209000-00005","article-title":"Can basal cells be seen in adenocarcinoma of the prostate?: an immunohistochemical study using high molecular weight cytokeratin (clone 34betaE12) antibody","volume":"26","author":"Oliai","year":"2002","journal-title":"Am J Surg Pathol"},{"issue":"3","key":"10.1016\/j.anndiagpath.2021.151727_bb0020","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1093\/ajcp\/aqw111","article-title":"MAGI-2 is a sensitive and specific marker of prostatic adenocarcinoma: a comparison with AMACR","volume":"146","author":"Goldstein","year":"2016","journal-title":"Am J Clin Pathol"},{"issue":"5","key":"10.1016\/j.anndiagpath.2021.151727_bb0025","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.humpath.2012.06.024","article-title":"The diagnostic use of ERG in resolving an \"atypical glands suspicious for cancer\" diagnosis in prostate biopsies beyond that provided by basal cell and alpha-methylacyl-CoA-racemase markers","volume":"44","author":"Shah","year":"2013","journal-title":"Hum Pathol"},{"issue":"2","key":"10.1016\/j.anndiagpath.2021.151727_bb0030","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.humpath.2014.10.010","article-title":"ERG and SALL4 expressions in SMARCB1\/INI1-deficient tumors: a useful tool for distinguishing epithelioid sarcoma from malignant rhabdoid tumor","volume":"46","author":"Kohashi","year":"2014","journal-title":"Hum Pathol"},{"issue":"1","key":"10.1016\/j.anndiagpath.2021.151727_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.abb.2007.07.027","article-title":"MAGI-2 inhibits cell migration and proliferation via PTEN in human hepatocarcinoma cells","volume":"467","author":"Hu","year":"2007","journal-title":"Arch Biochem Biophys"},{"issue":"13","key":"10.1016\/j.anndiagpath.2021.151727_bb0040","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1158\/1538-7445.AM2017-LB-245","article-title":"Abstract LB-245: Immunohistochemical study of MAGI-2 expression in lymphomas and carcinomas from prostate, urinary bladder, ovary, pancreas, liver, and colon","volume":"77","author":"Liao","year":"2017","journal-title":"American association for cancer research"},{"issue":"1","key":"10.1016\/j.anndiagpath.2021.151727_bb0045","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.juro.2011.10.053","article-title":"Minimal adenocarcinoma on prostate needle biopsy and false-negative diagnosis of malignancy","volume":"187","author":"Humphrey","year":"2012","journal-title":"J Urol"},{"issue":"1","key":"10.1016\/j.anndiagpath.2021.151727_bb0050","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.eururo.2016.02.029","article-title":"The 2016 WHO classification of tumours of the urinary system and male genital organs-part a: renal, penile, and testicular tumours","volume":"70","author":"Moch","year":"2016","journal-title":"Eur Urol"},{"issue":"4","key":"10.1016\/j.anndiagpath.2021.151727_bb0055","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1097\/PAS.0000000000000820","article-title":"Contemporary gleason grading of prostatic carcinoma: an update with discussion on practical issues to implement the 2014 International Society of Urological Pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma","volume":"41","author":"Epstein","year":"2016","journal-title":"Am J Surg Pathol"},{"issue":"2","key":"10.1016\/j.anndiagpath.2021.151727_bb0060","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/PAS.0000000000000530","article-title":"The 2014 International Society of Urological Pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma: definition of grading patterns and proposal for a new grading system","volume":"40","author":"Epstein","year":"2016","journal-title":"Am J Surg Pathol"},{"issue":"9","key":"10.1016\/j.anndiagpath.2021.151727_bb0065","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1097\/PAI.0000000000000686","article-title":"Immunohistochemical expression of microfibrillar-associated protein 5 (MFAP5) in invasive breast carcinoma of no special type","volume":"27","author":"Dawoud","year":"2019","journal-title":"Appl Immunohistochem Mol Morphol"},{"issue":"3","key":"10.1016\/j.anndiagpath.2021.151727_bb0070","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1530\/ERC-14-0586","article-title":"Expression of ERG protein in prostate cancer: variability and biological correlates","volume":"22","author":"Ayala","year":"2015","journal-title":"Endocr Relat Cancer"},{"issue":"1","key":"10.1016\/j.anndiagpath.2021.151727_bb0075","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s13048-018-0389-9","article-title":"Differential cyclooxygenase expression levels and survival associations in type I and type II ovarian tumors","volume":"11","author":"Beeghly-Fadiel","year":"2018","journal-title":"J Ovarian Res"},{"key":"10.1016\/j.anndiagpath.2021.151727_bb0080","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.humpath.2016.01.003","article-title":"MAGI-2 in prostate cancer: an immunohistochemical study","volume":"52","author":"Goldstein","year":"2016","journal-title":"Hum Pathol"},{"issue":"2","key":"10.1016\/j.anndiagpath.2021.151727_bb0085","doi-asserted-by":"crossref","first-page":"e84959","DOI":"10.1371\/journal.pone.0084959","article-title":"ERG rearrangement is associated with prostate cancer-related death in Chinese prostate cancer patients","volume":"9","author":"Qi","year":"2014","journal-title":"PLoS One"},{"issue":"28","key":"10.1016\/j.anndiagpath.2021.151727_bb0090","first-page":"3","article-title":"Evaluation of diagnostic tests in parallel and in series","volume":"3","author":"Franco","year":"2016","journal-title":"Giornale di Tecniche Nefrologiche e Dialitiche"},{"issue":"2","key":"10.1016\/j.anndiagpath.2021.151727_bb0095","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s13402-016-0268-6","article-title":"PSA and beyond: alternative prostate cancer biomarkers","volume":"39","author":"Saini","year":"2016","journal-title":"Cell Oncol (Dordr)"},{"key":"10.1016\/j.anndiagpath.2021.151727_bb0100","series-title":"Dataset for histopathology reports for prostatic carcinomaJune 2016, Jon Oxley M.V.a.D.B. city","author":"Standards and datasets for reporting cancers","year":"2016"},{"issue":"8","key":"10.1016\/j.anndiagpath.2021.151727_bb0105","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1097\/PAS.0000000000000254","article-title":"Best practices recommendations in the application of immunohistochemistry in urologic pathology: report from the International Society of Urological Pathology consensus conference","volume":"38","author":"Amin","year":"2014","journal-title":"Am J Surg Pathol"},{"issue":"8","key":"10.1016\/j.anndiagpath.2021.151727_bb0110","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1007\/s00432-015-2096-x","article-title":"ERG expression in prostate cancer: biological relevance and clinical implication","volume":"142","author":"Abou-Ouf","year":"2016","journal-title":"J Cancer Res Clin Oncol"},{"issue":"2","key":"10.1016\/j.anndiagpath.2021.151727_bb0115","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/bju.12262","article-title":"Interrogation of ERG gene rearrangements in prostate cancer identifies a prognostic 10-gene signature with relevant implication to patients' clinical outcome","volume":"113","author":"Bismar","year":"2014","journal-title":"BJU Int"},{"issue":"2","key":"10.1016\/j.anndiagpath.2021.151727_bb0120","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3889\/oamjms.2017.037","article-title":"Expression of ERG protein and TMRPSS2-ERG fusion in prostatic carcinoma in Egyptian patients","volume":"5","author":"Abdel-Hady","year":"2017","journal-title":"Open Access Maced J Med Sci"},{"issue":"11","key":"10.1016\/j.anndiagpath.2021.151727_bb0125","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1002\/pros.23004","article-title":"Association of ERG and TMPRSS2-ERG with grade, stage, and prognosis of prostate cancer is dependent on their expression levels","volume":"75","author":"Font-Tello","year":"2015","journal-title":"Prostate"},{"issue":"7333","key":"10.1016\/j.anndiagpath.2021.151727_bb0130","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1038\/nature09744","article-title":"The genomic complexity of primary human prostate cancer","volume":"470","author":"Berger","year":"2011","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.anndiagpath.2021.151727_bb0135","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1093\/jb\/mvv009","article-title":"MAGI2\/S-SCAM outside brain","volume":"157","author":"Nagashima","year":"2015","journal-title":"J Biochem"},{"issue":"17","key":"10.1016\/j.anndiagpath.2021.151727_bb0140","first-page":"4948","article-title":"MAGI-2 downregulation: a potential predictor of tumor progression and early recurrence in Han Chinese patients with prostate cancer","volume":"76","author":"Cao","year":"2020","journal-title":"Asian J Androl"},{"issue":"1","key":"10.1016\/j.anndiagpath.2021.151727_bb0145","first-page":"3","article-title":"Immunohistochemical evaluation of ERG expression in various benign and malignant tissues","volume":"43","author":"Liu","year":"2013","journal-title":"Ann Clin Lab Sci"},{"issue":"17","key":"10.1016\/j.anndiagpath.2021.151727_bb0150","doi-asserted-by":"crossref","first-page":"4948","DOI":"10.1158\/0008-5472.CAN-16-0902","article-title":"Integrated classification of prostate Cancer reveals a novel luminal subtype with poor outcome","volume":"76","author":"You","year":"2016","journal-title":"Cancer Res"},{"issue":"2","key":"10.1016\/j.anndiagpath.2021.151727_bb0155","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1097\/PDM.0b013e31829e0484","article-title":"A comparative study of ERG status assessment on DNA, mRNA, and protein levels using unique samples from a Swedish biopsy cohort","volume":"22","author":"Svensson","year":"2014","journal-title":"Appl Immunohistochem Mol Morphol"},{"issue":"9","key":"10.1016\/j.anndiagpath.2021.151727_bb0160","doi-asserted-by":"crossref","first-page":"12397","DOI":"10.1007\/s13277-016-5116-9","article-title":"TMPRSS2:ERG fusion gene occurs less frequently in Chinese patients with prostate cancer","volume":"37","author":"Jiang","year":"2016","journal-title":"Tumour Biol"},{"key":"10.1016\/j.anndiagpath.2021.151727_bb0165","first-page":"305","article-title":"p63 and cyclin D1 expression in benign prostatic hyperplasia versus prostatic adenocarcinoma: a clinicopathologic radiologic and immunohistochemical study","author":"Alqahtani","year":"2015","journal-title":"International Journal of Healthcare Sciences"},{"issue":"9","key":"10.1016\/j.anndiagpath.2021.151727_bb0170","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1007\/s00432-018-2685-6","article-title":"Association between pathologic factors and ERG expression in prostate cancer: finding pivotal networking","volume":"144","author":"Lee","year":"2018","journal-title":"J Cancer Res Clin Oncol"},{"issue":"1","key":"10.1016\/j.anndiagpath.2021.151727_bb0175","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.pathol.2017.09.008","article-title":"Contemporary prognostic indicators for prostate cancer incorporating International Society of Urological Pathology recommendations","volume":"50","author":"Egevad","year":"2018","journal-title":"Pathology"},{"issue":"13","key":"10.1016\/j.anndiagpath.2021.151727_bb0180","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.7150\/jca.16751","article-title":"Correlation between ERG fusion protein and androgen receptor expression by immunohistochemistry in prostate, possible role in diagnosis and therapy","volume":"8","author":"Navaei","year":"2017","journal-title":"J Cancer"},{"issue":"4","key":"10.1016\/j.anndiagpath.2021.151727_bb0185","doi-asserted-by":"crossref","first-page":"489","DOI":"10.4103\/0377-4929.191794","article-title":"Immunohistochemical expression of Ets-related gene-transcriptional factor in adenocarcinoma prostate and its correlation with Gleason score","volume":"59","author":"Mannan","year":"2016","journal-title":"Indian J Pathol Microbiol"},{"issue":"1","key":"10.1016\/j.anndiagpath.2021.151727_bb0190","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3233\/CBM-2012-00288","article-title":"CXCR4 mRNA overexpression in high grade prostate tumors: lack of association with TMPRSS2-ERG rearrangement","volume":"12","author":"de Muga","year":"2013","journal-title":"Cancer Biomark"},{"issue":"2","key":"10.1016\/j.anndiagpath.2021.151727_bb0195","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1593\/neo.07822","article-title":"Role of the TMPRSS2-ERG gene fusion in prostate cancer","volume":"10","author":"Tomlins","year":"2008","journal-title":"Neoplasia"},{"issue":"15","key":"10.1016\/j.anndiagpath.2021.151727_bb0200","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1002\/pros.22863","article-title":"ERG expression in prostate cancer: the prognostic paradox","volume":"74","author":"Taris","year":"2014","journal-title":"Prostate"}],"container-title":["Annals of Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913421000277?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913421000277?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T20:32:42Z","timestamp":1761078762000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1092913421000277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":40,"alternative-id":["S1092913421000277"],"URL":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2021.151727","relation":{},"ISSN":["1092-9134"],"issn-type":[{"value":"1092-9134","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative study of immunohistochemical expression of ERG and MAGI2 in prostatic carcinoma","name":"articletitle","label":"Article Title"},{"value":"Annals of Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2021.151727","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"151727"}}