{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T01:49:53Z","timestamp":1781056193214,"version":"3.54.1"},"reference-count":10,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100011912","name":"Washington University in St Louis School of Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Diagnostic Pathology"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.anndiagpath.2021.151740","type":"journal-article","created":{"date-parts":[[2021,3,31]],"date-time":"2021-03-31T13:20:48Z","timestamp":1617196848000},"page":"151740","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Ground-glass hepatocellular inclusions are associated with polypharmacy"],"prefix":"10.1016","volume":"52","author":[{"given":"Hsiang-Chih","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iv\u00e1n A.","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Byrnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anndiagpath.2021.151740_bb0005","doi-asserted-by":"crossref","unstructured":"Theise ND, Bodenheimer Jr. HC, Guido M. Viral hepatitis. In Burt AD, Ferrell LD, Hubscher SG (eds): MacSween's pathology of the liver, 7th Edition. Philadelphia, PA: Elsevier 2017; 372\u2013415.","DOI":"10.1016\/B978-0-7020-6697-9.00006-6"},{"key":"10.1016\/j.anndiagpath.2021.151740_bb0010","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1002\/j.2040-4603.2013.tb00527.x","article-title":"Broad spectrum of hepatocyte inclusions in humans, animals, and experimental models","volume":"3","author":"Strnad","year":"2013","journal-title":"Compr Physiol"},{"key":"10.1016\/j.anndiagpath.2021.151740_bb0015","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1097\/01.pas.0000208896.92988.fc","article-title":"Glycogen pseudoground glass change in hepatocytes","volume":"30","author":"Wisell","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.anndiagpath.2021.151740_bb0020","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1053\/j.gastro.2006.07.006","article-title":"Ground-glass, polyglucosan-like hepatocellular inclusions: a \u201cnew\u201d diagnostic entity","volume":"131","author":"Lefkowitch","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.anndiagpath.2021.151740_bb0025","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/s00428-006-0286-2","article-title":"Liver glycogen bodies: ground-glass hepatocytes in transplanted patients","volume":"449","author":"Bejarano","year":"2006","journal-title":"Virchows Arch"},{"key":"10.1016\/j.anndiagpath.2021.151740_bb0030","series-title":"The liver: an atlas and text of ultrastructural pathology","author":"Phillips","year":"1987"},{"key":"10.1016\/j.anndiagpath.2021.151740_bb0035","doi-asserted-by":"crossref","first-page":"13496","DOI":"10.1038\/ncomms13496","article-title":"Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic beta-cells","volume":"7","author":"Brereton","year":"2016","journal-title":"Nat Commun"},{"key":"10.1016\/j.anndiagpath.2021.151740_bb0040","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1056\/NEJMoa0900661","article-title":"Glycogenin-1 deficiency and inactivated priming of glycogen synthesis","volume":"362","author":"Moslemi","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.anndiagpath.2021.151740_bb0045","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s10545-016-9978-1","article-title":"Cardiomyopathy as presenting sign of glycogenin-1 deficiency-report of three cases and review of the literature","volume":"40","author":"Hedberg-Oldfors","year":"2017","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.anndiagpath.2021.151740_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.humpath.2020.04.004","article-title":"Rethinking fibrinogen storage disease of the liver: ground glass and globular inclusions do not represent a congenital metabolic disorder but acquired collective retention of proteins","volume":"100","author":"Zen","year":"2020","journal-title":"Hum Pathol"}],"container-title":["Annals of Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109291342100040X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109291342100040X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T20:33:32Z","timestamp":1761078812000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S109291342100040X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":10,"alternative-id":["S109291342100040X"],"URL":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2021.151740","relation":{},"ISSN":["1092-9134"],"issn-type":[{"value":"1092-9134","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ground-glass hepatocellular inclusions are associated with polypharmacy","name":"articletitle","label":"Article Title"},{"value":"Annals of Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2021.151740","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"151740"}}