{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T06:36:37Z","timestamp":1784874997313,"version":"3.55.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Diagnostic Pathology"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.anndiagpath.2023.152178","type":"journal-article","created":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T02:16:48Z","timestamp":1689128208000},"page":"152178","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Histology and clinical correlations in autoimmune hepatitis, primary biliary cholangitis, and autoimmune hepatitis-primary biliary cholangitis overlap syndrome"],"prefix":"10.1016","volume":"67","author":[{"given":"Yuanxin","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binny","family":"Khandakar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yansheng","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqin","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bella L.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuchen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anndiagpath.2023.152178_bb0005","article-title":"The many faces and pathologic diagnostic challenges of autoimmune hepatitis","author":"Zhang","year":"2022","journal-title":"Hum Pathol"},{"issue":"2","key":"10.1016\/j.anndiagpath.2023.152178_bb0010","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1002\/hep.31065","article-title":"Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American Association for the Study of Liver Diseases","volume":"72","author":"Mack","year":"2020","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.anndiagpath.2023.152178_bb0015","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/hep4.1148","article-title":"New scoring classification for primary biliary cholangitis-autoimmune hepatitis overlap syndrome","volume":"2","author":"Zhang","year":"2018","journal-title":"Hepatol Commun"},{"issue":"2","key":"10.1016\/j.anndiagpath.2023.152178_bb0020","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.jhep.2010.09.002","article-title":"Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue","volume":"54","author":"Boberg","year":"2011","journal-title":"J Hepatol"},{"issue":"6","key":"10.1016\/j.anndiagpath.2023.152178_bb0025","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.cgh.2010.03.004","article-title":"Paris criteria are effective in diagnosis of primary biliary cirrhosis and autoimmune hepatitis overlap syndrome","volume":"8","author":"Kuiper","year":"2010","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"12","key":"10.1016\/j.anndiagpath.2023.152178_bb0030","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1097\/MEG.0000000000001876","article-title":"Early histopathologic changes in primary biliary cholangitis: does \u2018minimal change\u2019 primary biliary cholangitis exist? A pathologist's view","volume":"33","author":"Chatzipantelis","year":"2021","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"4","key":"10.1016\/j.anndiagpath.2023.152178_bb0035","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.jhep.2007.07.006","article-title":"Grading and staging systems for inflammation and fibrosis in chronic liver diseases","volume":"47","author":"Goodman","year":"2007","journal-title":"J Hepatol"},{"issue":"5","key":"10.1016\/j.anndiagpath.2023.152178_bb0040","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/modpathol.2016.267","article-title":"Autoimmune hepatitis: review of histologic features included in the simplified criteria proposed by the international autoimmune hepatitis group and proposal for new histologic criteria","volume":"30","author":"Balitzer","year":"2017","journal-title":"Mod Pathol"},{"issue":"5","key":"10.1016\/j.anndiagpath.2023.152178_bb0045","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/cld.667","article-title":"Pathological patterns of biliary disease","volume":"10","author":"Lewis","year":"2017","journal-title":"Clin Liver Dis (Hoboken)"},{"key":"10.1016\/j.anndiagpath.2023.152178_bb0050","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.humpath.2018.07.014","article-title":"Histologic features of autoimmune hepatitis: a critical appraisal","volume":"82","author":"Gurung","year":"2018","journal-title":"Hum Pathol"},{"issue":"2","key":"10.1016\/j.anndiagpath.2023.152178_bb0055","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s13317-013-0046-7","article-title":"Autoantibodies in liver disease: important clues for the diagnosis, disease activity and prognosis","volume":"4","author":"Himoto","year":"2013","journal-title":"Auto Immun Highlights"},{"issue":"4\u20135","key":"10.1016\/j.anndiagpath.2023.152178_bb0060","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.autrev.2014.01.041","article-title":"The diagnosis of primary biliary cirrhosis","volume":"13","author":"Bowlus","year":"2014","journal-title":"Autoimmun Rev"},{"issue":"13","key":"10.1016\/j.anndiagpath.2023.152178_bb0065","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.3748\/wjg.v20.i13.3597","article-title":"Clinicopathological study of primary biliary cirrhosis with interface hepatitis compared to autoimmune hepatitis","volume":"20","author":"Kobayashi","year":"2014","journal-title":"World J Gastroenterol"},{"issue":"3","key":"10.1016\/j.anndiagpath.2023.152178_bb0070","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/cld.873","article-title":"Immunopathogenesis of autoimmune hepatitis","volume":"15","author":"Assis","year":"2020","journal-title":"Clin Liver Dis (Hoboken)"},{"issue":"2","key":"10.1016\/j.anndiagpath.2023.152178_bb0075","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1097\/MOG.0000000000000703","article-title":"Primary biliary cholangitis: pathogenic mechanisms","volume":"37","author":"Prieto","year":"2021","journal-title":"Curr Opin Gastroenterol"},{"issue":"1.2","key":"10.1016\/j.anndiagpath.2023.152178_bb0080","doi-asserted-by":"crossref","first-page":"7","DOI":"10.2152\/jmi.64.7","article-title":"Primary biliary cholangitis: its pathological characteristics and immunopathological mechanisms","volume":"64","author":"Tsuneyama","year":"2017","journal-title":"J Med Invest"},{"issue":"3","key":"10.1016\/j.anndiagpath.2023.152178_bb0085","doi-asserted-by":"crossref","first-page":"185","DOI":"10.32074\/1591-951X-241","article-title":"Pathology of autoimmune hepatitis","volume":"113","author":"Covelli","year":"2021","journal-title":"Pathologica"},{"issue":"29","key":"10.1016\/j.anndiagpath.2023.152178_bb0090","doi-asserted-by":"crossref","first-page":"22229","DOI":"10.1074\/jbc.M001563200","article-title":"Regulation of F-actin and endoplasmic reticulum organization by the trimeric G-protein Gi2 in rat hepatocytes. Implication for the activation of store-operated Ca2+ inflow","volume":"275","author":"Wang","year":"2000","journal-title":"J Biol Chem"},{"issue":"8","key":"10.1016\/j.anndiagpath.2023.152178_bb0095","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.autrev.2009.02.023","article-title":"Smooth muscle autoantibodies with F-actin specificity","volume":"8","author":"Soares","year":"2009","journal-title":"Autoimmun Rev"},{"issue":"5\u20136","key":"10.1016\/j.anndiagpath.2023.152178_bb0100","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.mito.2004.07.024","article-title":"Mitochondria and autoimmunity in primary biliary cirrhosis","volume":"4","author":"Ichiki","year":"2004","journal-title":"Mitochondrion"},{"issue":"6","key":"10.1016\/j.anndiagpath.2023.152178_bb0105","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.cgh.2012.02.010","article-title":"Patients with autoimmune hepatitis who have antimitochondrial antibodies need long-term follow-up to detect late development of primary biliary cirrhosis","volume":"10","author":"Dinani","year":"2012","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"4","key":"10.1016\/j.anndiagpath.2023.152178_bb0110","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S1568-9972(03)00013-2","article-title":"Antinuclear antibodies specific for primary biliary cirrhosis","volume":"2","author":"Worman","year":"2003","journal-title":"Autoimmun Rev"},{"issue":"2","key":"10.1016\/j.anndiagpath.2023.152178_bb0115","first-page":"326","article-title":"The overlap syndromes of autoimmune hepatitis","volume":"58","author":"Czaja","year":"2013","journal-title":"Dig Dis Sci"},{"issue":"21","key":"10.1016\/j.anndiagpath.2023.152178_bb0120","doi-asserted-by":"crossref","first-page":"3368","DOI":"10.3748\/wjg.14.3368","article-title":"Overlap syndromes among autoimmune liver diseases","volume":"14","author":"Rust","year":"2008","journal-title":"World J Gastroenterol"},{"issue":"3","key":"10.1016\/j.anndiagpath.2023.152178_bb0125","first-page":"392","article-title":"Characteristics and inpatient outcomes of primary biliary cholangitis and autoimmune hepatitis overlap syndrome","volume":"9","author":"Jiang","year":"2021","journal-title":"J Clin Transl Hepatol"},{"issue":"7","key":"10.1016\/j.anndiagpath.2023.152178_bb0130","first-page":"OD07","article-title":"Autoimmune hepatitis - primary biliary cirrhosis overlap syndrome","volume":"11","author":"Bairy","year":"2017","journal-title":"J Clin Diagn Res"},{"issue":"2","key":"10.1016\/j.anndiagpath.2023.152178_bb0135","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.jhep.2005.10.017","article-title":"Long term outcome and response to therapy of primary biliary cirrhosis-autoimmune hepatitis overlap syndrome","volume":"44","author":"Chazouilleres","year":"2006","journal-title":"J Hepatol"},{"issue":"2","key":"10.1016\/j.anndiagpath.2023.152178_bb0140","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.jhep.2005.11.037","article-title":"Overlap syndrome of primary biliary cirrhosis and autoimmune hepatitis: a foray across diagnostic boundaries","volume":"44","author":"Czaja","year":"2006","journal-title":"J Hepatol"}],"container-title":["Annals of Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109291342300076X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109291342300076X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T20:37:01Z","timestamp":1761079021000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S109291342300076X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":28,"alternative-id":["S109291342300076X"],"URL":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2023.152178","relation":{},"ISSN":["1092-9134"],"issn-type":[{"value":"1092-9134","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Histology and clinical correlations in autoimmune hepatitis, primary biliary cholangitis, and autoimmune hepatitis-primary biliary cholangitis overlap syndrome","name":"articletitle","label":"Article Title"},{"value":"Annals of Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2023.152178","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"152178"}}