{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T08:11:29Z","timestamp":1778832689695,"version":"3.51.4"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100007835","name":"Wenzhou Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007835","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007824","name":"Soochow University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007824","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Diagnostic Pathology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.anndiagpath.2026.152644","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T20:35:59Z","timestamp":1776112559000},"page":"152644","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Features and molecular genetic study of low-grade oncocytic tumor of the kidney"],"prefix":"10.1016","volume":"83","author":[{"given":"Jing","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yajie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanyan","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yifan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjuan","family":"Gan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152644_bb0005","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.eururo.2022.06.016","article-title":"The 2022 World Health Organization classification of tumours of the urinary system and male genital organs-part a: renal, penile, and testicular tumours","volume":"82","author":"Moch","year":"2022","journal-title":"Eur Urol"},{"issue":"2","key":"10.1016\/j.anndiagpath.2026.152644_bb0010","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/his.13865","article-title":"Low-grade oncocytic tumour of kidney (CD117-negative, cytokeratin 7-positive): a distinct entity?","volume":"75","author":"Trpkov","year":"2019","journal-title":"Histopathology"},{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152644_bb0015","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1007\/s00428-022-03283-x","article-title":"Low-grade oncocytic tumor of kidney harboring TSC\/MTOR mutation: clinicopathologic, immunohistochemical and molecular characteristics support a distinct entity","volume":"480","author":"Zhang","year":"2022","journal-title":"Virchows Arch"},{"issue":"3","key":"10.1016\/j.anndiagpath.2026.152644_bb0020","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s00428-020-02927-0","article-title":"Characterization of a distinct low-grade oncocytic renal tumor (CD117-negative and cytokeratin 7-positive) based on a tertiary oncology center experience: the new evidence from China","volume":"478","author":"Guo","year":"2021","journal-title":"Virchows Arch"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152644_bb0025","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1053\/j.semdp.2023.09.001","article-title":"Pathology of hereditary renal cell carcinoma syndromes: tuberous sclerosis complex (TSC)","volume":"41","author":"Machacek","year":"2024","journal-title":"Semin Diagn Pathol"},{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152644_bb0030","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1007\/s00428-023-03673-9","article-title":"Evaluation of an institutional series of low-grade oncocytic tumor (LOT) of the kidney and review of the mutational landscape of LOT","volume":"483","author":"Ricci","year":"2023","journal-title":"Virchows Arch"},{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152644_bb0035","first-page":"405","article-title":"Low-grade oncocytic tumor (LOT) - a new renal entity ready for a prime time: an updated review","volume":"37","author":"Mansoor","year":"2022","journal-title":"Histol Histopathol"},{"key":"10.1016\/j.anndiagpath.2026.152644_bb0040","doi-asserted-by":"crossref","DOI":"10.3389\/pore.2023.1610852","article-title":"Low-grade oncocytic tumour (LOT) of the kidney is characterised by GATA3 positivity, FOXI1 negativity and mTOR pathway mutations","volume":"29","author":"Chen","year":"2023","journal-title":"Pathol Oncol Res"},{"key":"10.1016\/j.anndiagpath.2026.152644_bb0045","doi-asserted-by":"crossref","DOI":"10.3389\/pore.2025.1612150","article-title":"Low-grade oncocytic tumor of the kidney-a clinical, pathological, and next generation sequencing-based study of 20 tumors","volume":"31","author":"Jenei","year":"2025","journal-title":"Pathol Oncol Res"},{"issue":"11","key":"10.1016\/j.anndiagpath.2026.152644_bb0050","first-page":"1186","article-title":"CD117-positive eosinophilic renal cell tumors with uncertain classification: a clinicopathological and molecular genetic analysis of 10 cases","volume":"54","author":"Xie","year":"2025","journal-title":"Chin J Pathol"},{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152644_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.modpat.2024.100467","article-title":"L1 cell adhesion molecule (L1CAM) expression and molecular alterations distinguish low-grade oncocytic tumor from eosinophilic chromophobe renal cell carcinoma","volume":"37","author":"Alghamdi","year":"2024","journal-title":"Mod Pathol"},{"issue":"7","key":"10.1016\/j.anndiagpath.2026.152644_bb0060","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1083\/jcb.143.7.2067","article-title":"The cell adhesion molecule L1 is developmentally regulated in the renal epithelium and is involved in kidney branching morphogenesis","volume":"143","author":"Debiec","year":"1998","journal-title":"J Cell Biol"},{"issue":"15","key":"10.1016\/j.anndiagpath.2026.152644_bb0065","doi-asserted-by":"crossref","DOI":"10.3390\/cancers17152440","article-title":"L1CAM reliably distinguishes low-grade oncocytic tumor from other eosinophilic renal neoplasms: a multicenter immunohistochemical study with diagnostic implications","volume":"17","author":"Scuccimarri","year":"2025","journal-title":"Cancers (Basel)"},{"issue":"2","key":"10.1016\/j.anndiagpath.2026.152644_bb0070","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1177\/10668969231178032","article-title":"Concordance of MTOR pathway mutations and the diagnosis of renal low-grade oncocytic tumor (LOT)","volume":"32","author":"Siegmund","year":"2024","journal-title":"Int J Surg Pathol"},{"issue":"3","key":"10.1016\/j.anndiagpath.2026.152644_bb0075","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/s41379-021-00896-6","article-title":"Germline and sporadic mTOR pathway mutations in low-grade oncocytic tumor of the kidney","volume":"35","author":"Kapur","year":"2022","journal-title":"Mod Pathol"},{"issue":"11","key":"10.1016\/j.anndiagpath.2026.152644_bb0080","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1016\/j.jtho.2023.07.024","article-title":"Clinicogenomic features and targetable mutations in NSCLCs harboring BRAF non-V600E mutations: a multi-institutional genomic screening study (LC-SCRUM-Asia)","volume":"18","author":"Sakai","year":"2023","journal-title":"J Thorac Oncol"},{"issue":"7","key":"10.1016\/j.anndiagpath.2026.152644_bb0085","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1136\/jcp-2024-209711","article-title":"Frequency and clinicopathologic features of renal low-grade oncocytic tumour and eosinophilic vacuolated tumour: reclassification of 605 eosinophilic tumours including patients managed with active surveillance","volume":"78","author":"Choiniere","year":"2025","journal-title":"J Clin Pathol"}],"container-title":["Annals of Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913426000407?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913426000407?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T07:38:30Z","timestamp":1778830710000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1092913426000407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":17,"alternative-id":["S1092913426000407"],"URL":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2026.152644","relation":{},"ISSN":["1092-9134"],"issn-type":[{"value":"1092-9134","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Features and molecular genetic study of low-grade oncocytic tumor of the kidney","name":"articletitle","label":"Article Title"},{"value":"Annals of Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2026.152644","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"152644"}}