{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:13:09Z","timestamp":1788970389549,"version":"build-2803163510"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Diagnostic Pathology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.anndiagpath.2026.152673","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T16:33:17Z","timestamp":1782145997000},"page":"152673","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Unusual morphologic features in molecularly defined high-grade sarcomas of the uterus"],"prefix":"10.1016","volume":"85","author":[{"given":"Khadijah","family":"Abdulhaleem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen W.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Nohr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveena","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Naso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent","family":"Jim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjelica","family":"Hodgson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Hoang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anndiagpath.2026.152673_bb0005","series-title":"Female genital tumours [Internet]. [cited 2025 Apr 28]. Female genital tumours","author":"WHO Classification of Tumours Editorial Board","year":"2020"},{"issue":"4","key":"10.1016\/j.anndiagpath.2026.152673_bb0010","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1097\/PAS.0000000000001437","article-title":"Uterine cervical sarcoma with a novel RET-SPECC1L fusion in an adult: a case which expands the homology between RET-rearranged and NTRK-rearranged tumors","volume":"44","author":"Weisman","year":"2020","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.anndiagpath.2026.152673_bb0015","article-title":"COL1A1-PDGFB fusion uterine fibrosarcoma: a case report with treatment implication","volume":"31","author":"Grindstaff","year":"2019","journal-title":"Gynecol Oncol Rep"},{"issue":"9","key":"10.1016\/j.anndiagpath.2026.152673_bb0020","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1097\/PAS.0000000000001915","article-title":"Recurrent KAT6B\/a::KANSL1 fusions characterize a potentially aggressive uterine sarcoma morphologically overlapping with low-grade endometrial stromal sarcoma","volume":"46","author":"Agaimy","year":"2022","journal-title":"Am J Surg Pathol"},{"issue":"6","key":"10.1016\/j.anndiagpath.2026.152673_bb0025","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1038\/s41379-021-00744-7","article-title":"Recurrent MEIS1-NCOA2\/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts","volume":"34","author":"Kao","year":"2021","journal-title":"Mod Pathol"},{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152673_bb0030","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1097\/PAS.0000000000001844","article-title":"GLI1 gene alterations in neoplasms of the genitourinary and gynecologic tract","volume":"46","author":"Argani","year":"2022","journal-title":"Am J Surg Pathol"},{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152673_bb0035","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1097\/PAS.0000000000001644","article-title":"Neurofibrosarcoma revisited: an institutional case series of uterine sarcomas harboring kinase-related fusions with report of a novel FGFR1-TACC1 fusion","volume":"45","author":"Devereaux","year":"2021","journal-title":"Am J Surg Pathol"},{"issue":"6","key":"10.1016\/j.anndiagpath.2026.152673_bb0040","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1007\/s00401-016-1539-z","article-title":"Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology","volume":"131","author":"Qaddoumi","year":"2016","journal-title":"Acta Neuropathol (Berl)"},{"issue":"6099","key":"10.1016\/j.anndiagpath.2026.152673_bb0045","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1126\/science.1220834","article-title":"Transforming fusions of FGFR and TACC genes in human glioblastoma","volume":"337","author":"Singh","year":"2012","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152673_bb0050","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1186\/s12967-016-1075-6","article-title":"FGFR1 and NTRK3 actionable alterations in \u201cwild-type\u201d gastrointestinal stromal tumors","volume":"14","author":"Shi","year":"2016","journal-title":"J Transl Med"},{"issue":"4","key":"10.1016\/j.anndiagpath.2026.152673_bb0055","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.28805","article-title":"A novel finding in pediatric leiomyosarcoma: expanding spectrum of FGFR rearrangements in childhood cancers","volume":"68","author":"Persaud","year":"2021","journal-title":"Pediatr Blood Cancer"},{"issue":"6","key":"10.1016\/j.anndiagpath.2026.152673_bb0060","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/PGP.0000000000000846","article-title":"Uterine sarcoma with FGFR1-TACC1 gene fusion: a case report and review of the literature","volume":"41","author":"Zyla","year":"2022","journal-title":"Int J Gynecol Pathol"},{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152673_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.modpat.2024.100474","article-title":"Expanding the spectrum of NR4A3 fusion\u2013positive gynecologic leiomyosarcomas","volume":"37","author":"Momeni-Boroujeni","year":"2024","journal-title":"Mod Pathol"},{"issue":"8","key":"10.1016\/j.anndiagpath.2026.152673_bb0070","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/S1470-2045(23)00275-9","article-title":"Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study","volume":"24","author":"Pant","year":"2023","journal-title":"Lancet Oncol"},{"issue":"20","key":"10.1016\/j.anndiagpath.2026.152673_bb0075","doi-asserted-by":"crossref","first-page":"4572","DOI":"10.1158\/1078-0432.CCR-24-0012","article-title":"Evaluating Debio 1347 in patients with FGFR fusion-positive advanced solid tumors from the FUZE multicenter, open-label, phase II basket trial","volume":"30","author":"Grivas","year":"2024","journal-title":"Clin Cancer Res"},{"issue":"6","key":"10.1016\/j.anndiagpath.2026.152673_bb0080","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1038\/s41591-024-02934-7","article-title":"Pemigatinib in previously treated solid tumors with activating FGFR1-FGFR3 alterations: phase 2 FIGHT-207 basket trial","volume":"30","author":"Rod\u00f3n","year":"2024","journal-title":"Nat Med"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152673_bb0085","doi-asserted-by":"crossref","first-page":"00582","DOI":"10.1183\/23120541.00582-2020","article-title":"A new KIF5B\u2013ERBB4 gene fusion in a lung adenocarcinoma patient","volume":"7","author":"Guenzi","year":"2021","journal-title":"ERJ Open Res"},{"issue":"8","key":"10.1016\/j.anndiagpath.2026.152673_bb0090","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.4161\/cc.9.8.11239","article-title":"A growing family: adding mutated Erbb4 as a novel cancer target","volume":"9","author":"Rudloff","year":"2010","journal-title":"Cell Cycle"},{"issue":"12","key":"10.1016\/j.anndiagpath.2026.152673_bb0095","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1158\/1078-0432.CCR-14-0107","article-title":"Druggable oncogene fusions in invasive mucinous lung adenocarcinoma","volume":"20","author":"Nakaoku","year":"2014","journal-title":"Clin Cancer Res"},{"issue":"9","key":"10.1016\/j.anndiagpath.2026.152673_bb0100","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1182\/blood-2016-03-707141","article-title":"Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma","volume":"128","author":"Boddicker","year":"2016","journal-title":"Blood"},{"issue":"2","key":"10.1016\/j.anndiagpath.2026.152673_bb0105","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/ijc.30081","article-title":"Characterization of functionally active gene fusions in human papillomavirus related oropharyngeal squamous cell carcinoma","volume":"139","author":"Guo","year":"2016","journal-title":"Int J Cancer"},{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152673_bb0110","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1097\/PGP.0000000000000826","article-title":"Description of a novel ERBB4-rearranged uterine sarcoma","volume":"41","author":"Lim","year":"2022","journal-title":"Int J Gynecol Pathol"},{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152673_bb0115","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1007\/s00428-024-03908-3","article-title":"ERBB2\/ ERBB3-mutated S100\/ SOX10-positive unclassified high-grade uterine sarcoma: first detailed description of a novel entity","volume":"485","author":"Agaimy","year":"2024","journal-title":"Virchows Arch"},{"issue":"S3","key":"10.1016\/j.anndiagpath.2026.152673_bb0120","first-page":"S941","article-title":"Recurrent activating ERBB2 V777L point mutation in fusion-negative, S100 and SOX10-positive uterine (corpus and cervix) spindle cell neoplasms","volume":"103","author":"Lin","year":"2023","journal-title":"Lab Investig"},{"issue":"3","key":"10.1016\/j.anndiagpath.2026.152673_bb0125","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s00428-024-04003-3","article-title":"ERBB2\/ERBB3-mutated S100\/SOX10-positive uterine sarcoma: something new","volume":"486","author":"Shi","year":"2025","journal-title":"Virchows Arch"},{"issue":"6","key":"10.1016\/j.anndiagpath.2026.152673_bb0130","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1007\/s00428-025-04257-5","article-title":"ERBB2\/ERBB3-mutated S100\/SOX10-positive high-grade uterine sarcoma-a case report on a rare entity","volume":"488","author":"Huang","year":"2026","journal-title":"Virchows Arch"},{"issue":"3","key":"10.1016\/j.anndiagpath.2026.152673_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.labinv.2025.105276","article-title":"986 \u201cFibrosarcoma-like\u201d tumors of the gynecologic tract show overlapping morphology but distinct molecular subgroups including those with gene fusions and recurrent ERBB2\/3 mutations","volume":"106","author":"Marshall","year":"2026","journal-title":"Lab Investig"},{"issue":"6","key":"10.1016\/j.anndiagpath.2026.152673_bb0140","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s00428-024-03936-z","article-title":"S100 and CD34 positive spindle cell tumors of the uterine cervix with EGFR mutation: a hitherto unrecognized neoplasm phenotypically and epigenetically overlapping with \u201cNTRK-rearranged spindle cell neoplasms\u201d of the uterus","volume":"486","author":"Michal","year":"2025","journal-title":"Virchows Arch"},{"issue":"6","key":"10.1016\/j.anndiagpath.2026.152673_bb0145","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1111\/his.14870","article-title":"Dedifferentiated leiomyosarcoma of the uterus: a clinicopathologic and immunohistochemical analysis of 23 cases","volume":"82","author":"Chapel","year":"2023","journal-title":"Histopathology"},{"issue":"6","key":"10.1016\/j.anndiagpath.2026.152673_bb0150","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1111\/his.14292","article-title":"p53 immunohistochemical analysis of fusion-positive uterine sarcomas","volume":"78","author":"Mohammad","year":"2021","journal-title":"Histopathology"},{"issue":"10","key":"10.1016\/j.anndiagpath.2026.152673_bb0155","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1097\/PAS.0000000000001929","article-title":"NTRK-rearranged uterine sarcomas: Clinicopathologic features of 15 cases, literature review, and risk stratification","volume":"46","author":"Costigan","year":"2022","journal-title":"Am J Surg Pathol"},{"issue":"10","key":"10.1016\/j.anndiagpath.2026.152673_bb0160","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1097\/PAS.0b013e31825fa931","article-title":"Cyclin D1 as a diagnostic immunomarker for endometrial stromal sarcoma with YWHAE-FAM22 rearrangement","volume":"36","author":"Lee","year":"2012","journal-title":"Am J Surg Pathol"},{"issue":"5","key":"10.1016\/j.anndiagpath.2026.152673_bb0165","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1038\/s41379-020-00705-6","article-title":"Targeted RNA expression profiling identifies high-grade endometrial stromal sarcoma as a clinically relevant molecular subtype of uterine sarcoma","volume":"34","author":"Momeni-Boroujeni","year":"2021","journal-title":"Mod Pathol"}],"container-title":["Annals of Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913426000699?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913426000699?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:32:26Z","timestamp":1788967946000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1092913426000699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":33,"alternative-id":["S1092913426000699"],"URL":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2026.152673","relation":{},"ISSN":["1092-9134"],"issn-type":[{"value":"1092-9134","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unusual morphologic features in molecularly defined high-grade sarcomas of the uterus","name":"articletitle","label":"Article Title"},{"value":"Annals of Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2026.152673","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"152673"}}