{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:13:14Z","timestamp":1788970394071,"version":"build-2803163510"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Diagnostic Pathology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.anndiagpath.2026.152704","type":"journal-article","created":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T22:24:17Z","timestamp":1786227857000},"page":"152704","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Stroma AReactive Invasion Front Areas (SARIFA) is associated with dissemination-related histopathological features in Clark level V cutaneous melanoma"],"prefix":"10.1016","volume":"85","author":[{"given":"Ahmet","family":"Boduro\u011flu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naz\u0131mcan","family":"Tezel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin","family":"\u00c7ak\u0131r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"02","key":"10.1016\/j.anndiagpath.2026.152704_bb0005","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/CM9.0000000000003416","article-title":"Recent global patterns in skin cancer incidence, mortality, and prevalence","volume":"138","author":"Wang","year":"2025","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.anndiagpath.2026.152704_bb0010","doi-asserted-by":"crossref","DOI":"10.1177\/10732748241227340","article-title":"Global, regional, and national incidence trend analysis of malignant skin melanoma between 1990 and 2019, and projections until 2034","volume":"31","author":"Yuan","year":"2024","journal-title":"Cancer Control"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152704_bb0015","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.neo.2021.11.013","article-title":"Spatiotemporal trends of the global burden of melanoma in 204 countries and territories from 1990 to 2019: results from the 2019 global burden of disease study","volume":"24","author":"Li","year":"2022","journal-title":"Neoplasia"},{"issue":"16","key":"10.1016\/j.anndiagpath.2026.152704_bb0020","doi-asserted-by":"crossref","DOI":"10.3346\/jkms.2019.34.e126","article-title":"Clinicopathologic features and prognostic factors of primary cutaneous melanoma: a multicenter study in Korea","volume":"34","author":"Kim","year":"2019","journal-title":"J Korean Med Sci"},{"issue":"10","key":"10.1016\/j.anndiagpath.2026.152704_bb0025","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines11102616","article-title":"The impact of clinical and histopathological factors on disease progression and survival in thick cutaneous melanomas","volume":"11","author":"\u021a\u0103poi","year":"2023","journal-title":"Biomedicines"},{"issue":"4","key":"10.1016\/j.anndiagpath.2026.152704_bb0030","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/cup.14561","article-title":"Can angiotropism and lymphovascular invasion refine the current cutaneous melanoma staging system?","volume":"51","author":"Namubiru","year":"2024","journal-title":"J Cutan Pathol"},{"issue":"12","key":"10.1016\/j.anndiagpath.2026.152704_bb0035","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1002\/cbin.70085","article-title":"Matter of fat: cancer-associated adipocytes as mediators of tumor progression and immune evasion","volume":"49","author":"Sureka","year":"2025","journal-title":"Cell Biol Int"},{"issue":"12","key":"10.1016\/j.anndiagpath.2026.152704_bb0040","doi-asserted-by":"crossref","DOI":"10.1111\/obr.13833","article-title":"Lipids and adipocytes involvement in tumor progression with a focus on obesity and diet","volume":"25","author":"Calabrese","year":"2024","journal-title":"Obes Rev"},{"issue":"3","key":"10.1016\/j.anndiagpath.2026.152704_bb0045","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s10555-022-10059-x","article-title":"The adipocyte microenvironment and cancer","volume":"41","author":"Mukherjee","year":"2022","journal-title":"Cancer Metastasis Rev"},{"issue":"11","key":"10.1016\/j.anndiagpath.2026.152704_bb0050","doi-asserted-by":"crossref","DOI":"10.3390\/cancers12113147","article-title":"Lipid metabolic reprogramming: role in melanoma progression and therapeutic perspectives","volume":"12","author":"Pellerin","year":"2020","journal-title":"Cancers"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152704_bb0055","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s11658-023-00476-3","article-title":"Melanoma cells induce dedifferentiation and metabolic changes in adipocytes present in the tumor niche","volume":"28","author":"Simiczyjew","year":"2023","journal-title":"Cell Mol Biol Lett"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152704_bb0060","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s10120-023-01436-8","article-title":"Stroma AReactive Invasion Front Areas (SARIFA) proves prognostic relevance in gastric carcinoma and is based on a tumor\u2013adipocyte interaction indicating an altered immune response","volume":"27","author":"Grosser","year":"2024","journal-title":"Gastric Cancer"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152704_bb0065","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/s41698-024-00662-2","article-title":"The SARIFA biomarker in the context of basic research of lipid-driven cancers","volume":"8","author":"M\u00e4rkl","year":"2024","journal-title":"NPJ Precis Oncol"},{"issue":"19","key":"10.1016\/j.anndiagpath.2026.152704_bb0070","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13194880","article-title":"Stroma AReactive Invasion Front Areas (SARIFA)\u2014a new easily to determine biomarker in colon cancer\u2014results of a retrospective study","volume":"13","author":"Martin","year":"2021","journal-title":"Cancers (Basel)"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152704_bb0075","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/path.5810","article-title":"Stroma AReactive Invasion Front Areas (SARIFA)\u2013a new prognostic biomarker in gastric cancer related to tumor-promoting adipocytes","volume":"256","author":"Grosser","year":"2022","journal-title":"J Pathol"},{"issue":"2","key":"10.1016\/j.anndiagpath.2026.152704_bb0080","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/s41417-023-00695-y","article-title":"Novel biomarker SARIFA in colorectal cancer: highly prognostic, not genetically driven and histologic indicator of a distinct tumor biology","volume":"31","author":"Reitsam","year":"2024","journal-title":"Cancer Gene Ther"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152704_bb0085","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12885-023-11771-9","article-title":"SARIFA as a new histopathological biomarker is associated with adverse clinicopathological characteristics, tumor-promoting fatty-acid metabolism, and might predict a metastatic pattern in pT3a prostate cancer","volume":"24","author":"Enke","year":"2024","journal-title":"BMC Cancer"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152704_bb0090","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1186\/s12885-024-12519-9","article-title":"The Concept of Stroma AReactive Invasion Front Areas (SARIFA) as a new prognostic biomarker for lipid-driven cancers holds true in pancreatic ductal adenocarcinoma","volume":"24","author":"Grochowski","year":"2024","journal-title":"BMC Cancer"},{"issue":"1","key":"10.1016\/j.anndiagpath.2026.152704_bb0095","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"issue":"7","key":"10.1016\/j.anndiagpath.2026.152704_bb0100","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1038\/s41379-020-0500-9","article-title":"The prognostic significance of microsatellites in cutaneous melanoma","volume":"33","author":"Niebling","year":"2020","journal-title":"Mod Pathol"},{"issue":"9","key":"10.1016\/j.anndiagpath.2026.152704_bb0105","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/s41416-025-02972-z","article-title":"Stroma AReactive Invasion Front Areas (SARIFA), tumour immune microenvironment, and survival in colorectal cancer","volume":"132","author":"Tapiainen","year":"2025","journal-title":"Br J Cancer"},{"issue":"13","key":"10.1016\/j.anndiagpath.2026.152704_bb0110","doi-asserted-by":"crossref","first-page":"8026","DOI":"10.1245\/s10434-023-14050-w","article-title":"Prognostic significance of sentinel lymph node status in thick primary melanomas (>4 mm)","volume":"30","author":"Holmberg","year":"2023","journal-title":"Ann Surg Oncol"}],"container-title":["Annals of Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913426001000?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1092913426001000?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:32:45Z","timestamp":1788967965000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1092913426001000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":22,"alternative-id":["S1092913426001000"],"URL":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2026.152704","relation":{},"ISSN":["1092-9134"],"issn-type":[{"value":"1092-9134","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stroma AReactive Invasion Front Areas (SARIFA) is associated with dissemination-related histopathological features in Clark level V cutaneous melanoma","name":"articletitle","label":"Article Title"},{"value":"Annals of Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anndiagpath.2026.152704","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"152704"}}