{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T02:41:49Z","timestamp":1760928109464,"version":"build-2065373602"},"reference-count":38,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Epidemiology"],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1016\/j.annepidem.2006.03.005","type":"journal-article","created":{"date-parts":[[2006,12,21]],"date-time":"2006-12-21T10:14:16Z","timestamp":1166696056000},"page":"57-63","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Long-Term Change in Cholesterol in Relation to Inflammation-Sensitive Plasma Proteins: A Longitudinal Study"],"prefix":"10.1016","volume":"17","author":[{"given":"Gunnar","family":"Engstr\u00f6m","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Hedblad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Janzon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Folke","family":"Lindg\u00e4rde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.annepidem.2006.03.005_bib1","doi-asserted-by":"crossref","first-page":"2632","DOI":"10.1161\/01.CIR.0000017327.69909.FF","article-title":"The effects of cholesterol and inflammation-sensitive proteins on incidence of stroke and myocardial infarction","volume":"105","author":"Engstr\u00f6m","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.annepidem.2006.03.005_bib2","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1055\/s-0037-1613566","article-title":"Fibrin(ogen) in cardiovascular disease: An update","volume":"89","author":"Koenig","year":"2003","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.annepidem.2006.03.005_bib3","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.2337\/diacare.23.12.1835","article-title":"Association between C-reactive protein and features of the metabolic syndrome: A population-based study","volume":"23","author":"Frohlich","year":"2000","journal-title":"Diabetes Care"},{"key":"10.1016\/j.annepidem.2006.03.005_bib4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","article-title":"Atherosclerosis\u2014An inflammatory disease","volume":"340","author":"Ross","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.annepidem.2006.03.005_bib5","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.annepidem.2003.09.006","article-title":"Predictors of falling cholesterol levels in older adults: The Cardiovascular Health Study","volume":"14","author":"Manolio","year":"2004","journal-title":"Ann Epidemiol"},{"key":"10.1016\/j.annepidem.2006.03.005_bib6","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1161\/01.CIR.0000080288.30567.86","article-title":"Inflammation modifies the effects of a reduced-fat low-cholesterol diet on lipids: Results from the DASH-sodium trial","volume":"108","author":"Erlinger","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.annepidem.2006.03.005_bib7","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/(SICI)1096-9896(199703)181:3<257::AID-PATH756>3.0.CO;2-U","article-title":"Cytokines and the hepatic acute phase response","volume":"181","author":"Moshage","year":"1997","journal-title":"J Pathol"},{"key":"10.1016\/j.annepidem.2006.03.005_bib8","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1194\/jlr.R300019-JLR200","article-title":"Effects of infection and inflammation on lipid and lipoprotein metabolism: Mechanisms and consequences to the host","volume":"45","author":"Khovidhunkit","year":"2004","journal-title":"J Lipid Res"},{"key":"10.1016\/j.annepidem.2006.03.005_bib9","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.clnu.2004.08.004","article-title":"Dyslipidemia and inflammation: An evolutionary conserved mechanism","volume":"24","author":"Esteve","year":"2005","journal-title":"Clin Nutr"},{"key":"10.1016\/j.annepidem.2006.03.005_bib10","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0005-2760(94)00240-Y","article-title":"Regulation of lecithin:cholesterol acyltransferase by TGF-beta and interleukin-6","volume":"1255","author":"Skretting","year":"1995","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.annepidem.2006.03.005_bib11","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/S0022-2275(20)30471-5","article-title":"Identification of an IL-6 response element in the human LCAT promoter","volume":"43","author":"Feister","year":"2002","journal-title":"J Lipid Res"},{"key":"10.1016\/j.annepidem.2006.03.005_bib12","first-page":"4113","article-title":"Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: A possible role for interleukin 6 in cancer cachexia","volume":"52","author":"Greenberg","year":"1992","journal-title":"Cancer Res"},{"key":"10.1016\/j.annepidem.2006.03.005_bib13","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1172\/JCI118707","article-title":"Endotoxin and cytokines decrease serum levels and extra hepatic protein and mRNA levels of cholesteryl ester transfer protein in Syrian hamsters","volume":"97","author":"Hardardottir","year":"1996","journal-title":"J Clin Invest"},{"issue":"Suppl 1","key":"10.1016\/j.annepidem.2006.03.005_bib14","first-page":"S66","article-title":"Beneficial effects of cytokine induced hyperlipidemia","volume":"37","author":"Feingold","year":"1998","journal-title":"Z Ernahrungswiss"},{"key":"10.1016\/j.annepidem.2006.03.005_bib15","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.tcm.2004.03.003","article-title":"Endothelial lipase: A modulator of lipoprotein metabolism upregulated by inflammation","volume":"14","author":"Broedl","year":"2004","journal-title":"Trends Cardiovasc Med"},{"key":"10.1016\/j.annepidem.2006.03.005_bib16","doi-asserted-by":"crossref","first-page":"E957","DOI":"10.1152\/ajpendo.2001.281.5.E957","article-title":"Reduced body fat and increased hepatic lipid synthesis in mice bearing interleukin-6-secreting tumor","volume":"281","author":"Metzger","year":"2001","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.annepidem.2006.03.005_bib17","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1046\/j.1365-2796.1996.483819000.x","article-title":"Cardiovascular risk groups and mortality in an urban Swedish male population: The Malm\u00f6 Preventive Project","volume":"239","author":"Berglund","year":"1996","journal-title":"J Intern Med"},{"key":"10.1016\/j.annepidem.2006.03.005_bib18","unstructured":"Treatment of hyperlipidemia [In Swedish]. Information from the medical products agency in Sweden. 1995;3:178\u2013187."},{"key":"10.1016\/j.annepidem.2006.03.005_bib19","first-page":"77","article-title":"Strategies for the prevention of coronary heart disease. A policy statement of the European Atherosclerosis Society","volume":"8","author":"European Atherosclerosis Society","year":"1987","journal-title":"Eur Heart J"},{"key":"10.1016\/j.annepidem.2006.03.005_bib20","doi-asserted-by":"crossref","first-page":"442","DOI":"10.2337\/diabetes.52.2.442","article-title":"Inflammation-sensitive plasma proteins, diabetes, and mortality and incidence of myocardial infarction and stroke: A population-based study","volume":"52","author":"Engstr\u00f6m","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.annepidem.2006.03.005_bib21","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1360-0443.1982.tb02459.x","article-title":"Indicators of alcohol consumption: Comparisons between a questionnaire (Mm-MAST), interviews and serum gamma-glutamyl transferase (GGT) in a health survey of middle-aged males","volume":"77","author":"Kristenson","year":"1982","journal-title":"Br\u00a0J Addict"},{"key":"10.1016\/j.annepidem.2006.03.005_bib22","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1161\/01.ATV.0000200100.14612.bb","article-title":"Occupation, marital status, and low-grade inflammation: Mutual confounding or independent cardiovascular risk factors?","volume":"26","author":"Engstr\u00f6m","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.annepidem.2006.03.005_bib23","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.3109\/00365517209102748","article-title":"Electroimmuno assay","volume":"124","author":"Laurell","year":"1972","journal-title":"Scand J Clin Lab Invest Suppl"},{"key":"10.1016\/j.annepidem.2006.03.005_bib24","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1161\/01.ATV.21.3.452","article-title":"Influence of plasma fibrinogen levels on the incidence of myocardial infarction and death is modified by other inflammation-sensitive proteins: A long-term cohort study","volume":"21","author":"Lind","year":"2001","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.annepidem.2006.03.005_bib25","first-page":"403","article-title":"Enzymatische bestimmung des gesamt-cholesterins in serum","volume":"12","author":"Roschlau","year":"1974","journal-title":"Z Klin Chem Klin Biochem"},{"key":"10.1016\/j.annepidem.2006.03.005_bib26","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1210\/jcem.85.3.6555","article-title":"Interleukin-6 gene polymorphism and lipid abnormalities in healthy subjects","volume":"85","author":"Fernandez-Real","year":"2000","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.annepidem.2006.03.005_bib27","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3109\/00365519709099406","article-title":"Low density lipoprotein catabolism is enhanced by the cleaved form of alpha-1-antitrypsin","volume":"57","author":"Janciauskiene","year":"1997","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1016\/j.annepidem.2006.03.005_bib28","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/mrd.1021","article-title":"Haptoglobin inhibits lecithin-cholesterol acyltransferase in human ovarian follicular fluid","volume":"59","author":"Balestrieri","year":"2001","journal-title":"Mol Reprod Dev"},{"key":"10.1016\/j.annepidem.2006.03.005_bib29","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1172\/JCI117127","article-title":"Intact human ceruloplasmin oxidatively modifies low density lipoprotein","volume":"93","author":"Ehrenwald","year":"1994","journal-title":"J Clin Invest"},{"key":"10.1016\/j.annepidem.2006.03.005_bib30","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0163-7258(03)00055-X","article-title":"The lipid and non-lipid effects of statins","volume":"99","author":"Wierzbicki","year":"2003","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.annepidem.2006.03.005_bib31","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/j.jacc.2003.04.001","article-title":"The effects of rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, on markers of endothelial cell activation, C-reactive protein, and fibrinogen levels in non-diabetic coronary artery disease patients","volume":"42","author":"Sidhu","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.annepidem.2006.03.005_bib32","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1056\/NEJM199704033361401","article-title":"Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men","volume":"336","author":"Ridker","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1016\/j.annepidem.2006.03.005_bib33","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1161\/01.ATV.0000041842.43905.F3","article-title":"Blood pressure increase and incidence of hypertension in relation to inflammation-sensitive proteins","volume":"22","author":"Engstr\u00f6m","year":"2002","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.annepidem.2006.03.005_bib34","doi-asserted-by":"crossref","first-page":"570","DOI":"10.2337\/diabetes.54.2.570","article-title":"Complement C3 is a risk factor for the development of diabetes. A population-based cohort study","volume":"54","author":"Engstr\u00f6m","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.annepidem.2006.03.005_bib35","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.2337\/diabetes.52.8.2097","article-title":"Inflammations-sensitive plasma proteins are associated with future weight gain","volume":"52","author":"Engstr\u00f6m","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.annepidem.2006.03.005_bib36","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1093\/ajcn\/79.6.969","article-title":"Dietary fatty acids affect plasma markers of inflammation in healthy men fed controlled diets: A randomized crossover study","volume":"79","author":"Baer","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.annepidem.2006.03.005_bib37","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/ajcn\/75.3.492","article-title":"Relation between a diet with a high glycemic load and plasma concentrations of high-sensitivity C-reactive protein in middle-aged women","volume":"75","author":"Liu","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.annepidem.2006.03.005_bib38","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.metabol.2004.06.010","article-title":"Association between diet, lifestyle, metabolic cardiovascular risk factors, and plasma C-reactive protein levels","volume":"53","author":"Fredrikson","year":"2004","journal-title":"Metabolism"}],"container-title":["Annals of Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047279706000743?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047279706000743?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T02:02:58Z","timestamp":1760925778000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1047279706000743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["S1047279706000743"],"URL":"https:\/\/doi.org\/10.1016\/j.annepidem.2006.03.005","relation":{},"ISSN":["1047-2797"],"issn-type":[{"type":"print","value":"1047-2797"}],"subject":[],"published":{"date-parts":[[2007,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-Term Change in Cholesterol in Relation to Inflammation-Sensitive Plasma Proteins: A Longitudinal Study","name":"articletitle","label":"Article Title"},{"value":"Annals of Epidemiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.annepidem.2006.03.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}