{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:57:50Z","timestamp":1789189070451,"version":"build-2803163510"},"reference-count":22,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Epidemiology"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1016\/j.annepidem.2011.03.010","type":"journal-article","created":{"date-parts":[[2011,5,10]],"date-time":"2011-05-10T03:02:15Z","timestamp":1304996535000},"page":"727-731","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Worldwide Clinical Interventional Studies on Leading Causes of Death: A Descriptive Analysis"],"prefix":"10.1016","volume":"21","author":[{"given":"Rafael","family":"Dal-R\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.annepidem.2011.03.010_bib1","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1136\/bmj.327.7422.1041","article-title":"Working Group of Academy of Medical Sciences. Resuscitating clinical research in the United Kingdom","volume":"327","author":"Bell","year":"2003","journal-title":"BMJ"},{"issue":"7","key":"10.1016\/j.annepidem.2011.03.010_bib2","first-page":"e6425","article-title":"The Impact of National Institutes of Health Funding on U.S","volume":"4","author":"Lyubarova","year":"2009","journal-title":"Cardiovascular Disease Research. PLoS ONE"},{"key":"10.1016\/j.annepidem.2011.03.010_bib3","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S0140-6736(06)69010-7","article-title":"Funding for practice-oriented clinical research","volume":"368","author":"Rothwell","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.annepidem.2011.03.010_bib4","doi-asserted-by":"crossref","first-page":"E152","DOI":"10.25011\/cim.v30i4.1776","article-title":"Clinical research lags behind biomedical, population-based health, and health services research at multiple levels","volume":"30","author":"Raghavan","year":"2007","journal-title":"Clin Invest Med"},{"key":"10.1016\/j.annepidem.2011.03.010_bib5","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1177\/0115426507022006609","article-title":"Funding nutrition research: where\u2019s the money?","volume":"22","author":"Thomson","year":"2007","journal-title":"Nutr Clin Pract"},{"key":"10.1016\/j.annepidem.2011.03.010_bib6","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1747-4949.2007.00126.x","article-title":"Worldwide under-funding of stroke research","volume":"2","author":"Pendlebury","year":"2007","journal-title":"Int J Stroke"},{"key":"10.1016\/j.annepidem.2011.03.010_bib7","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/mds.22446","article-title":"Funding of Parkinson research from industry and US federal and foundation sources","volume":"24","author":"Dorsey","year":"2009","journal-title":"Mov Disord"},{"key":"10.1016\/j.annepidem.2011.03.010_bib8","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1016\/j.jacc.2009.03.024","article-title":"How one program at the National Heart, Lung, and Blood Institute establishes its scientific priorities","volume":"53","author":"Bild","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.annepidem.2011.03.010_bib9","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1016\/S0140-6736(01)06891-X","article-title":"Industry-sponsored clinical research: a double-edged sword","volume":"358","author":"Montaner","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.annepidem.2011.03.010_bib10","doi-asserted-by":"crossref","first-page":"325","DOI":"10.2515\/therapie:2006059","article-title":"Public-private partnership models in France and in Europe","volume":"61","author":"Demotes-Mainard","year":"2006","journal-title":"Therapie"},{"key":"10.1016\/j.annepidem.2011.03.010_bib11","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1001\/jama.2009.1655","article-title":"Clinical research sites\u2014the underappreciated component of the clinical research system","volume":"302","author":"Califf","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.annepidem.2011.03.010_bib12","unstructured":"World Health Organization 2008, \u201cGlobal Burden of Disease, 2004 update\u201d. Available at: http:\/\/www.who.int\/healthinfo\/global_burden_disease\/2004_report_update\/en\/index.html. Accessed July 9th, 2010."},{"key":"10.1016\/j.annepidem.2011.03.010_bib13","doi-asserted-by":"crossref","first-page":"477","DOI":"10.7326\/0003-4819-141-6-200409210-00109","article-title":"Clinical trial registration: a statement from the international Committee of Medical Journal, Eds","volume":"141","author":"De Angelis","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.annepidem.2011.03.010_bib14","unstructured":"Food and Drug Administration Amendments Act of 2007. Available at: http:\/\/frwebgate.access.gpo.gov\/cgi-bin\/getdoc.cgi?dbname=110_cong_public_laws&docid=f:publ085.110. Accessed July 12th, 2010."},{"key":"10.1016\/j.annepidem.2011.03.010_bib15","unstructured":"Current controlled trials. Available at: http:\/\/www.controlled-trials.com\/. Accessed March 12th 2010."},{"key":"10.1016\/j.annepidem.2011.03.010_bib16","doi-asserted-by":"crossref","first-page":"e442","DOI":"10.1371\/journal.pmed.0030442","article-title":"Projections of global mortality and burden of disease from 2002 to 2030","volume":"3","author":"Mathers","year":"2006","journal-title":"PLoS Med"},{"key":"10.1016\/j.annepidem.2011.03.010_bib17","unstructured":"World Health Organization. Global Strategy on Diet, Physical Activity and Health. Diabetes. Available at: http:\/\/www.who.int\/dietphysicalactivity\/publications\/facts\/diabetes\/en\/. Accessed July 12th 2010."},{"key":"10.1016\/j.annepidem.2011.03.010_bib18","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.2337\/diacare.27.5.1047","article-title":"Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030","volume":"27","author":"Wild","year":"2004","journal-title":"Diabetes Care"},{"key":"10.1016\/j.annepidem.2011.03.010_bib19","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/nrc1781","article-title":"Predicting the future burden of cancer","volume":"6","author":"Bray","year":"2006","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.annepidem.2011.03.010_bib20","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/S0140-6736(09)61798-0","article-title":"Diarrhoea: why children are still dying and what can be done","volume":"375","author":"Wardlaw","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.annepidem.2011.03.010_bib21","first-page":"213","article-title":"Meeting of the immunization Strategic Advisory Group of Experts, April 2009\u2014conclusions and recommendations","volume":"84","year":"2009","journal-title":"Wkly Epidemiol Rec"},{"key":"10.1016\/j.annepidem.2011.03.010_bib22","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1001\/jama.297.19.2112","article-title":"Issues in the registration of clinical trials","volume":"297","author":"Zarin","year":"2007","journal-title":"JAMA"}],"container-title":["Annals of Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047279711001098?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047279711001098?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T02:10:44Z","timestamp":1760926244000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1047279711001098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":22,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["S1047279711001098"],"URL":"https:\/\/doi.org\/10.1016\/j.annepidem.2011.03.010","relation":{},"ISSN":["1047-2797"],"issn-type":[{"value":"1047-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Worldwide Clinical Interventional Studies on Leading Causes of Death: A Descriptive Analysis","name":"articletitle","label":"Article Title"},{"value":"Annals of Epidemiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.annepidem.2011.03.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}