{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:55:42Z","timestamp":1790517342447,"version":"4.1.0"},"reference-count":46,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Annals of Otorhinolaryngology, Head and Neck Diseases"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.anorl.2017.06.006","type":"journal-article","created":{"date-parts":[[2017,7,6]],"date-time":"2017-07-06T16:17:31Z","timestamp":1499357851000},"page":"339-345","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"title":["Cell therapy and vocal fold scarring"],"prefix":"10.1016","volume":"134","author":[{"given":"A.","family":"Mattei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Magalon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Bertrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Philandrianos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Veran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Giovanni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.anorl.2017.06.006_bib0235","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1007\/s00405-013-2498-9","article-title":"Vocal fold scars: current concepts and future directions. Consensus report of the phonosurgery committee of the European laryngological society","volume":"270","author":"Friedrich","year":"2013","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.anorl.2017.06.006_bib0240","first-page":"239","article-title":"Phonosurgery. Basic and clinical investigations","volume":"21","author":"Hirano","year":"1975","journal-title":"Otologia"},{"issue":"8","key":"10.1016\/j.anorl.2017.06.006_bib0245","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1002\/lary.21817","article-title":"Recruitment patterns of side population cells during wound healing in rat vocal folds","volume":"121","author":"Gugatschka","year":"2011","journal-title":"Laryngoscope"},{"issue":"7","key":"10.1016\/j.anorl.2017.06.006_bib0250","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1080\/00016480500470147","article-title":"Viscoelastic measurements after vocal fold scarring in rabbits\u00a0\u2013\u00a0short-term results after hyaluronan injection","volume":"126","author":"Hertegard","year":"2006","journal-title":"Acta Otolaryngol"},{"issue":"4","key":"10.1016\/j.anorl.2017.06.006_bib0255","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.otohns.2009.12.035","article-title":"Auto-crosslinked hyaluronan gel injections in phonosurgery","volume":"142","author":"Molteni","year":"2010","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.anorl.2017.06.006_bib0465","series-title":"Bone and mineral research","first-page":"243","article-title":"Osteogenic stem cells in bone marrow","author":"Friedenstein","year":"1990"},{"issue":"3","key":"10.1016\/j.anorl.2017.06.006_bib0265","doi-asserted-by":"crossref","first-page":"132","DOI":"10.2302\/kjm.54.132","article-title":"Multipotential differentiation of adipose tissue-derived stem cells","volume":"54","author":"Strem","year":"2005","journal-title":"Keio J Med"},{"issue":"12","key":"10.1016\/j.anorl.2017.06.006_bib0270","doi-asserted-by":"crossref","first-page":"E461","DOI":"10.1002\/lary.24816","article-title":"Adipose-derived stem cells versus bone marrow-derived stem cells for vocal fold regeneration","volume":"124","author":"Hiwatashi","year":"2014","journal-title":"Laryngoscope"},{"issue":"5","key":"10.1016\/j.anorl.2017.06.006_bib0275","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1002\/lary.25667","article-title":"Comparison of ASCs and BMSCs combined with atelocollagen for vocal fold scar regeneration","volume":"126","author":"Hiwatashi","year":"2016","journal-title":"Laryngoscope"},{"issue":"11","key":"10.1016\/j.anorl.2017.06.006_bib0280","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1097\/MLG.0b013e3181379c7c","article-title":"Injection of embryonic stem cells into scarred rabbit vocal folds enhances healing and improves viscoelasticity: short-term results","volume":"117","author":"Cedervall","year":"2007","journal-title":"Laryngoscope"},{"key":"10.1016\/j.anorl.2017.06.006_bib0285","doi-asserted-by":"crossref","first-page":"754876","DOI":"10.1155\/2015\/754876","article-title":"Stem cell therapy in injured vocal folds: a three-month xenograft analysis of human embryonic stem cells","volume":"2015","author":"Svensson","year":"2015","journal-title":"Biomed Res Int"},{"issue":"36","key":"10.1016\/j.anorl.2017.06.006_bib0290","doi-asserted-by":"crossref","first-page":"9026","DOI":"10.1016\/j.biomaterials.2013.08.004","article-title":"The use of laryngeal mucosa mesenchymal stem cells for the repair the vocal fold injury","volume":"34","author":"Peng","year":"2013","journal-title":"Biomaterials"},{"issue":"4","key":"10.1016\/j.anorl.2017.06.006_bib0295","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1002\/lary.20149","article-title":"Crosstalk between adipose-derived stem\/stromal cells and vocal fold fibroblasts in vitro","volume":"119","author":"Kumai","year":"2009","journal-title":"Laryngoscope"},{"issue":"2","key":"10.1016\/j.anorl.2017.06.006_bib0300","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/lary.20753","article-title":"Modulation of vocal fold scar fibroblasts by adipose-derived stem\/stromal cells","volume":"120","author":"Kumai","year":"2010","journal-title":"Laryngoscope"},{"issue":"1","key":"10.1016\/j.anorl.2017.06.006_bib0305","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/lary.20642","article-title":"Chronic vocal fold scar restoration with hepatocyte growth factor hydrogel","volume":"120","author":"Kishimoto","year":"2010","journal-title":"Laryngoscope"},{"issue":"3","key":"10.1016\/j.anorl.2017.06.006_bib0310","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1097\/00005537-200403000-00030","article-title":"Prevention of vocal fold scarring by topical injection of hepatocyte growth factor in a rabbit model","volume":"114","author":"Hirano","year":"2004","journal-title":"Laryngoscope"},{"issue":"5","key":"10.1016\/j.anorl.2017.06.006_bib0315","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1002\/term.1757","article-title":"Cell-cell interaction between vocal fold fibroblasts and bone marrow mesenchymal stromal cells in three-dimensional hyaluronan hydrogel","volume":"10","author":"Chen","year":"2016","journal-title":"J Tissue Eng Regen Med"},{"issue":"1","key":"10.1016\/j.anorl.2017.06.006_bib0320","doi-asserted-by":"crossref","first-page":"E35","DOI":"10.1002\/lary.26121","article-title":"Mesenchymal stem cells have antifibrotic effects on transforming growth factor-\u03b21-stimulated vocal fold fibroblasts","volume":"127","author":"Hiwatashi","year":"2016","journal-title":"Laryngoscope"},{"issue":"10","key":"10.1016\/j.anorl.2017.06.006_bib0325","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1002\/lary.22143","article-title":"Injection of human mesenchymal stem cells improves healing of vocal folds after scar excision\u00a0\u2013\u00a0a xenograft analysis","volume":"121","author":"Svensson","year":"2011","journal-title":"Laryngoscope"},{"issue":"7","key":"10.1016\/j.anorl.2017.06.006_bib0330","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1002\/lary.20926","article-title":"Injection of human mesenchymal stem cells improves healing of scarred vocal folds: analysis using a xenograft model","volume":"120","author":"Svensson","year":"2010","journal-title":"Laryngoscope"},{"issue":"2","key":"10.1016\/j.anorl.2017.06.006_bib0335","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1177\/000348941112000209","article-title":"Adipose-derived mesenchymal stem cells in collagen-hyaluronic acid gel composite scaffolds for vocal fold regeneration","volume":"120","author":"Xu","year":"2011","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"3","key":"10.1016\/j.anorl.2017.06.006_bib0340","doi-asserted-by":"crossref","first-page":"E64","DOI":"10.1002\/lary.24405","article-title":"Adipose-derived stem cell-containing hyaluronic acid\/alginate hydrogel improves vocal fold wound healing","volume":"124","author":"Kim","year":"2014","journal-title":"Laryngoscope"},{"issue":"4\u20136","key":"10.1016\/j.anorl.2017.06.006_bib0345","first-page":"735","article-title":"The combined effect of autologous mesenchymal stem cells and hepatocyte growth factor on vocal fold regeneration and fibrosis in vocal fold wound","volume":"5","author":"Kwon","year":"2008","journal-title":"J Tissue Eng Regen Med"},{"issue":"3\u20134","key":"10.1016\/j.anorl.2017.06.006_bib0350","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1159\/000099627","article-title":"The prevention of vocal fold scarring using autologous adipose tissue-derived stromal cells","volume":"184","author":"Lee","year":"2006","journal-title":"Cells Tissues Organs"},{"issue":"11","key":"10.1016\/j.anorl.2017.06.006_bib0355","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1177\/000348940311201101","article-title":"Regeneration of the vocal fold using autologous mesenchymal stem cells","volume":"112","author":"Kanemaru","year":"2003","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"4","key":"10.1016\/j.anorl.2017.06.006_bib0360","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1177\/0194599816628501","article-title":"Tissue-engineered vocal fold mucosa implantation in rabbits","volume":"154","author":"Shiba","year":"2016","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"6","key":"10.1016\/j.anorl.2017.06.006_bib0365","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1177\/000348941112000610","article-title":"Implantation of an atelocollagen sponge with autologous bone marrow-derived mesenchymal stromal cells for treatment of vocal fold scarring in a canine model","volume":"120","author":"Ohno","year":"2011","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"3","key":"10.1016\/j.anorl.2017.06.006_bib0370","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/lary.20782","article-title":"Tissue regeneration of the vocal fold using bone marrow mesenchymal stem cells and synthetic extracellular matrix injections in rats","volume":"120","author":"Johnson","year":"2010","journal-title":"Laryngoscope"},{"issue":"18","key":"10.1016\/j.anorl.2017.06.006_bib0375","doi-asserted-by":"crossref","first-page":"4911","DOI":"10.1016\/j.biomaterials.2014.03.008","article-title":"Small intestine submucosa and mesenchymal stem cells composite gel for scarless vocal fold regeneration","volume":"35","author":"Choi","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.anorl.2017.06.006_bib0380","doi-asserted-by":"crossref","first-page":"9010279","DOI":"10.1155\/2016\/5806875","article-title":"Adipose-derived mesenchymal stem cells in the regeneration of vocal folds: a study on a chronic vocal fold scar","volume":"2016","author":"Angelou","year":"2016","journal-title":"Stem Cells Int"},{"issue":"8","key":"10.1016\/j.anorl.2017.06.006_bib0385","doi-asserted-by":"crossref","first-page":"E278","DOI":"10.1002\/lary.25867","article-title":"Adipose stromal cells improve healing of vocal fold scar: morphological and functional evidences","volume":"126","author":"De Bonnecaze","year":"2016","journal-title":"Laryngoscope"},{"issue":"11","key":"10.1016\/j.anorl.2017.06.006_bib0390","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1055\/s-2007-997821","article-title":"[Basic principles for indications in phonosurgery]","volume":"74","author":"Friedrich","year":"1995","journal-title":"Laryngorhinootologie"},{"issue":"11","key":"10.1016\/j.anorl.2017.06.006_bib0395","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.3109\/00016489.2011.599816","article-title":"Vocal fold wound healing after injection of human adipose-derived stem cells in a rabbit model","volume":"131","author":"Hong","year":"2011","journal-title":"Acta Otolaryngol"},{"issue":"2","key":"10.1016\/j.anorl.2017.06.006_bib0400","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1177\/000348941312200208","article-title":"Bone marrow-derived clonal mesenchymal stem cells as a source of cell therapy for promoting vocal fold wound healing","volume":"122","author":"Kim","year":"2013","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"7","key":"10.1016\/j.anorl.2017.06.006_bib0405","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1097\/01.mlg.0000224548.68499.35","article-title":"Viscoelastic and histologic properties in scarred rabbit vocal folds after mesenchymal stem cell injection","volume":"116","author":"Hertegard","year":"2006","journal-title":"Laryngoscope"},{"issue":"12","key":"10.1016\/j.anorl.2017.06.006_bib0410","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1177\/000348940511401203","article-title":"Destiny of autologous bone marrow-derived stromal cells implanted in the vocal fold","volume":"114","author":"Kanemaru","year":"2005","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"3","key":"10.1016\/j.anorl.2017.06.006_bib0415","doi-asserted-by":"crossref","first-page":"e92676","DOI":"10.1371\/journal.pone.0092676","article-title":"Fibroblast-like cells differentiated from adipose-derived mesenchymal stem cells for vocal fold wound healing","volume":"9","author":"Hu","year":"2014","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.anorl.2017.06.006_bib0420","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.jcyt.2013.02.006","volume":"15","author":"Bourin","year":"2013","journal-title":"Cytotherapy"},{"issue":"3","key":"10.1016\/j.anorl.2017.06.006_bib0425","first-page":"177","article-title":"Patient factors influencing the concentration of stromal vascular fraction (SVF) for adipose-derived stromal cell (ASC) therapy in dogs","volume":"77","author":"Astor","year":"2013","journal-title":"Can J Vet Res"},{"issue":"2","key":"10.1016\/j.anorl.2017.06.006_bib0430","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jcyt.2013.11.011","article-title":"Phase I trial: the use of autologous cultured adipose-derived stroma\/stem cells to treat patients with non-revascularizable critical limb ischemia","volume":"16","author":"Bura","year":"2014","journal-title":"Cytotherapy"},{"issue":"4","key":"10.1016\/j.anorl.2017.06.006_bib0435","doi-asserted-by":"crossref","first-page":"H973","DOI":"10.1152\/ajpheart.00735.2011","article-title":"Adipose stromal vascular fraction cell construct sustains coronary microvascular function after acute myocardial infarction","volume":"302","author":"LeBlanc","year":"2012","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.anorl.2017.06.006_bib0440","first-page":"17","article-title":"Long term efficacy of subcutaneous injection of the autologous adipose-derived stromal vascular fraction (SVF) in the fingers of patients with systemic sclerosis","volume":"29","author":"Daumas","year":"2015","journal-title":"Fundam Clin Pharmacol"},{"issue":"1","key":"10.1016\/j.anorl.2017.06.006_bib0445","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1016\/S2352-3026(15)00224-0","article-title":"Survival after mesenchymal stromal cell therapy in steroid-refractory acute graft-versus-host disease: systematic review and meta-analysis","volume":"3","author":"Hashmi","year":"2016","journal-title":"Lancet Haematol"},{"issue":"5","key":"10.1016\/j.anorl.2017.06.006_bib0450","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1007\/s00167-013-2807-2","article-title":"Clinical results and second-look arthroscopic findings after treatment with adipose-derived stem cells for knee osteoarthritis","volume":"23","author":"Koh","year":"2015","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"issue":"5","key":"10.1016\/j.anorl.2017.06.006_bib0455","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1002\/ar.23086","article-title":"Behavior of in situ human native adipose tissue CD34+stromal\/progenitor cells during different stages of repair. Tissue-resident CD34+stromal cells as a source of myofibroblasts","volume":"298","author":"Diaz-Flores","year":"2015","journal-title":"Anat Rec Adv Integr Anat Evol Biol"},{"issue":"12","key":"10.1016\/j.anorl.2017.06.006_bib0460","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1136\/annrheumdis-2014-205681","article-title":"Safety, tolerability and potential efficacy of injection of autologous adipose-derived stromal vascular fraction in the fingers of patients with systemic sclerosis: an open-label phase I trial","volume":"74","author":"Granel","year":"2015","journal-title":"Ann Rheum Dis"}],"container-title":["European Annals of Otorhinolaryngology, Head and Neck Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879729617301035?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879729617301035?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,11]],"date-time":"2020-10-11T18:20:13Z","timestamp":1602440413000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1879729617301035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":46,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S1879729617301035"],"URL":"https:\/\/doi.org\/10.1016\/j.anorl.2017.06.006","relation":{},"ISSN":["1879-7296"],"issn-type":[{"value":"1879-7296","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cell therapy and vocal fold scarring","name":"articletitle","label":"Article Title"},{"value":"European Annals of Otorhinolaryngology, Head and Neck Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anorl.2017.06.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}]}}