{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T12:03:50Z","timestamp":1779883430088,"version":"3.53.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T00:00:00Z","timestamp":1643155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anales de Pediatr\u00eda (English Edition)"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.anpede.2020.10.017","type":"journal-article","created":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T17:01:54Z","timestamp":1643994114000},"page":"130-137","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Thyroid function in &lt; 32 weeks gestation preterm infants"],"prefix":"10.1016","volume":"96","author":[{"given":"Alicia","family":"Montaner-Ram\u00f3n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"Hern\u00e1ndez-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariadna","family":"Campos-Martorell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Ballesta-Anguiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Clemente-Le\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e9lix","family":"Castillo-Salinas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anpede.2020.10.017_bib0005","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1210\/jcem.87.4.8434","article-title":"Fetal tissues are exposed to biologically relevant free thyroxine concentrations during early phases of development","volume":"87","author":"Calvo","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.anpede.2020.10.017_bib0010","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1203\/00006450-199601000-00021","article-title":"The relation between thyroxine levels and neurodevelopmental outcome at age 5 and 9 years in a national cohort of very preterm and\/or very low weight infants","volume":"39","author":"Den Ouden","year":"1996","journal-title":"Pediatr Res"},{"key":"10.1016\/j.anpede.2020.10.017_bib0015","first-page":"13","article-title":"Funci\u00f3n tiroidea en la etapa fetal, neonatal y en el reci\u00e9n nacido prematuro. Necesidades de yodo","volume":"5","author":"Ares-Segura","year":"2014","journal-title":"Rev Esp Endocrinol Pediatr"},{"key":"10.1016\/j.anpede.2020.10.017_bib0020","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1530\/EJE-15-1233","article-title":"Congenital hypothyroidism with delayed TSH elevation in low-birth-weight infants: incidence, diagnosis and management","volume":"175","author":"Cavarzere","year":"2016","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.anpede.2020.10.017_bib0025","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1089\/10507250050137770","article-title":"Atypical hypothyroidism and the very low birthweight infant","volume":"10","author":"Mandel","year":"2000","journal-title":"Thyroid"},{"key":"10.1016\/j.anpede.2020.10.017_bib0030","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.earlhumdev.2006.09.007","article-title":"Transient hypothyroxinaemia in preterm infants","volume":"82","author":"Williams","year":"2006","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.anpede.2020.10.017_bib0035","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1016\/j.jpeds.2013.12.048","article-title":"Evolution of thyroid function in preterm infants detected by screening for congenital hypothyroidism","volume":"164","author":"Vigone","year":"2014","journal-title":"J Pediatr"},{"key":"10.1016\/j.anpede.2020.10.017_bib0040","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1053\/j.semperi.2008.09.003","article-title":"Thyroid system immaturities in very low birth weight premature infants","volume":"32","author":"Fisher","year":"2008","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.anpede.2020.10.017_bib0045","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1053\/j.semperi.2008.09.004","article-title":"Perinatal factors affecting thyroid hormone status in extreme preterm infants","volume":"32","author":"Williams","year":"2008","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.anpede.2020.10.017_bib0050","doi-asserted-by":"crossref","DOI":"10.1111\/j.1651-2227.2011.02536.x","article-title":"Permanent and transient congenital hypothyroidism in preterm infants","volume":"101","author":"Srinivasan","year":"2012","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.anpede.2020.10.017_bib0055","first-page":"42","article-title":"Trastornos endocrinol\u00f3gicos del reci\u00e9n nacido pret\u00e9rmino","volume":"60","author":"Clemente","year":"2004","journal-title":"An Pediatr"},{"key":"10.1016\/j.anpede.2020.10.017_bib0060","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1515\/JPEM.2007.20.12.1269","article-title":"Thyroid function in preterm infants 27-29 weeks of gestational age during the first four months of life: results from a prospective study comprising 80 preterm infants","volume":"20","author":"Clemente","year":"2007","journal-title":"J Pediatr Endocrinol Metab"},{"key":"10.1016\/j.anpede.2020.10.017_bib0065","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1159\/000487637","article-title":"Higher incidence rates of hypothyroidism and late TSH rise in preterm very-low-birth-weight infants at a tertiary care center","volume":"89","author":"Tfayli","year":"2018","journal-title":"Horm Res Paediatr"},{"key":"10.1016\/j.anpede.2020.10.017_bib0070","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.pedneo.2017.04.006","article-title":"Screening of congenital hypothyroidism in preterm, low birth weight and very low birth weight neonates: A systematic review","volume":"59","author":"Hashemipour","year":"2018","journal-title":"Pediatr Neonatol"},{"key":"10.1016\/j.anpede.2020.10.017_bib0075","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.jpeds.2010.10.018","article-title":"Congenital hypothyroidism with a delayed thyroid-stimulating hormone elevation in very premature infants: incidence and growth and developmental outcomes","volume":"158","author":"Woo","year":"2011","journal-title":"J Pediatr"},{"key":"10.1016\/j.anpede.2020.10.017_bib0080","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1007\/s10545-011-9286-8","article-title":"Newborn screening for congenital hypothyroidism in very-low-birth-weight babies: the need for a second test","volume":"34","author":"Bijarnia","year":"2011","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.anpede.2020.10.017_bib0085","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.jpeds.2014.02.031","article-title":"Screening preterm infants for congenital hypothyroidism: Better the second time around","volume":"164","author":"Lafranchi","year":"2014","journal-title":"J Pediatr"},{"key":"10.1016\/j.anpede.2020.10.017_bib0090","first-page":"7","article-title":"Valores de hormonas tiroideas en el prematuro y evoluci\u00f3n con la edad","volume":"9","author":"Segovia Ort\u00ed","year":"2018","journal-title":"Rev Esp Endocrinol Pediatr"},{"key":"10.1016\/j.anpede.2020.10.017_bib0095","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1089\/thy.1999.9.715","article-title":"Hypothyroxinemia in premature infants: is thyroxine treatment necessary?","volume":"9","author":"Fisher","year":"1999","journal-title":"Thyroid"},{"key":"10.1016\/j.anpede.2020.10.017_bib0100","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1053\/j.semperi.2008.09.008","article-title":"Trials with thyroid hormone in preterm infants: clinical and neurodevelopmental effects","volume":"32","author":"Van Wassenaer","year":"2008","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.anpede.2020.10.017_bib0105","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1210\/jc.2011-1073","article-title":"Is the incidence of congenital hypothyroidism really increasing? A 20-year retrospective population-based study in Qu\u00e9bec","volume":"96","author":"Delado\u00eby","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.anpede.2020.10.017_bib0110","doi-asserted-by":"crossref","first-page":"349","DOI":"10.21037\/tp.2017.09.07","article-title":"Transient hypothyroidism in the newborn: To treat or not to treat","volume":"6","author":"Kanike","year":"2017","journal-title":"Transl Pediatr"},{"key":"10.1016\/j.anpede.2020.10.017_bib0115","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2019-0290","article-title":"Thyroid-stimulating hormone reference ranges for preterm infants","volume":"144","author":"Kaluarachchi","year":"2019","journal-title":"Pediatrics"},{"key":"10.1016\/j.anpede.2020.10.017_bib0120","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.clinbiochem.2019.09.003","article-title":"Establishment of reference intervals for thyroid hormones in premature infants beyond the first week of life using Beckman Coulter Unicel DxI 800","volume":"74","author":"Wang","year":"2019","journal-title":"Clin Biochem"},{"key":"10.1016\/j.anpede.2020.10.017_bib0125","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1080\/14767058.2018.1441277","article-title":"Current knowledge of transient hypothyroxinemia of prematurity: to treat or not to treat?","volume":"32","author":"Iijima","year":"2019","journal-title":"J Matern Neonatal Med"},{"key":"10.1016\/j.anpede.2020.10.017_bib0130","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1515\/jpem-2018-0537","article-title":"Evolution of circulating thyroid hormone levels in preterm infants during the first week of life: Perinatal influences and impact on neurodevelopment","volume":"32","author":"Eerdekens","year":"2019","journal-title":"J Pediatr Endocrinol Metab"},{"key":"10.1016\/j.anpede.2020.10.017_bib0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12887-019-1792-0","article-title":"Thyroid dysfunction in preterm infants born before 32 gestational weeks","volume":"19","author":"Kim","year":"2019","journal-title":"BMC Pediatr"},{"issue":"11\u201312","key":"10.1016\/j.anpede.2020.10.017_bib0140","first-page":"897","article-title":"Neurodevelopment of preterm infants born at 28 to 36 weeks of gestational age: The role of hypothyroxinemia and long-term outcome at 4 years","volume":"24","author":"Ares","year":"2011","journal-title":"J Pediatr Endocrinol Metab"},{"key":"10.1016\/j.anpede.2020.10.017_bib0145","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1136\/bmj.312.7039.1132","article-title":"Low triiodothyronine concentration in preterm infants and subsequent intelligence quotient (IQ) at 8 year follow up","volume":"312","author":"Lucas","year":"1996","journal-title":"BMJ"},{"key":"10.1016\/j.anpede.2020.10.017_bib0150","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1089\/thy.2008.0282","article-title":"Impact of neonatal thyroid hormone insufficiency and medical morbidity on infant neurodevelopment and attention following preterm birth","volume":"19","author":"Simic","year":"2009","journal-title":"Thyroid"},{"key":"10.1016\/j.anpede.2020.10.017_bib0155","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1542\/peds.2013-2425","article-title":"Free thyroxine levels after very preterm birth and neurodevelopmental outcomes at age 7 years","volume":"133","author":"Scratch","year":"2014","journal-title":"Pediatrics"},{"key":"10.1016\/j.anpede.2020.10.017_bib0160","doi-asserted-by":"crossref","first-page":"e0222018","DOI":"10.1371\/journal.pone.0222018","article-title":"Lack of association between hypothyroxinemia of prematurity and transient thyroid abnormalities with adverse long term neurodevelopmental outcome in very low birth weight infants","volume":"14","author":"Tan","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.anpede.2020.10.017_bib0165","doi-asserted-by":"crossref","first-page":"4648","DOI":"10.1210\/jc.2015-3078","article-title":"No association between transient hypothyroxinemia of prematurity and neurodevelopmental outcome in young adulthood","volume":"100","author":"Hollanders","year":"2015","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.anpede.2020.10.017_bib0170","doi-asserted-by":"crossref","first-page":"4898","DOI":"10.1210\/jc.2010-0743","article-title":"Levels of neonatal thyroid hormone in preterm infants and neurodevelopmental outcome at 5 1\/2 years: millennium cohort study","volume":"95","author":"Delahunty","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.anpede.2020.10.017_bib0175","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1038\/jp.2016.266","article-title":"Effect of L-thyroxine supplementation on very low birth weight infants with transient hypothyroxinemia of prematurity at 3 years of age","volume":"37","author":"Uchiyama","year":"2017","journal-title":"J Perinatol"},{"key":"10.1016\/j.anpede.2020.10.017_bib0180","article-title":"Postnatal thyroid hormones for preterm infants with transient hypothyroxinaemia","author":"Osborn","year":"2007","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Anales de Pediatr\u00eda (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2341287922000126?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2341287922000126?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T09:44:25Z","timestamp":1762422265000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2341287922000126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["S2341287922000126"],"URL":"https:\/\/doi.org\/10.1016\/j.anpede.2020.10.017","relation":{},"ISSN":["2341-2879"],"issn-type":[{"value":"2341-2879","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Thyroid function in < 32 weeks gestation preterm infants","name":"articletitle","label":"Article Title"},{"value":"Anales de Pediatr\u00eda (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anpede.2020.10.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.anpedi.2020.10.023","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Espa\u00f1a, S.L.U. on behalf of Asociaci\u00f3n Espa\u00f1ola de Pediatr\u00eda.","name":"copyright","label":"Copyright"}]}}