{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T02:21:05Z","timestamp":1782958865430,"version":"3.54.5"},"reference-count":40,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,14]],"date-time":"2022-06-14T00:00:00Z","timestamp":1655164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anales de Pediatr\u00eda (English Edition)"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.anpede.2022.05.003","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T22:55:26Z","timestamp":1655506526000},"page":"60.e1-60.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Recommendations for transfusion of blood products in neonatology"],"prefix":"10.1016","volume":"97","author":[{"given":"Hector","family":"Boix","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Dolores","family":"S\u00e1nchez-Redondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Cernada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Gracia Espinosa","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noelia","family":"Gonz\u00e1lez-Pacheco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"P\u00e9rez-Mu\u00f1uzuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda L.","family":"Couce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.anpede.2022.05.003_bib0005","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.hoc.2019.01.013","article-title":"Updates in neonatal hematology: causes, risk factors, and management of anemia and thrombocytopenia","volume":"33","author":"Ree","year":"2019","journal-title":"Hematol Oncol Clin North Am."},{"issue":"4","key":"10.1016\/j.anpede.2022.05.003_bib0010","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1053\/j.semperi.2012.04.004","article-title":"International survey of transfusion practices for extremely premature infants","volume":"36","author":"Guill\u00e9n","year":"2012","journal-title":"Semin Perinatol."},{"issue":"6","key":"10.1016\/j.anpede.2022.05.003_bib0015","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1097\/00062752-200211000-00012","article-title":"Neonatal red blood cell transfusions","volume":"9","author":"Luban","year":"2002","journal-title":"Curr Opin Hematol."},{"key":"10.1016\/j.anpede.2022.05.003_bib0020","article-title":"Low versus high haemoglobin concentration threshold for blood transfusion for preventing morbidity and mortality in very low birth weight infants","volume":"11","author":"Whyte","year":"2011","journal-title":"Cochrane Data-Base Syst Rev."},{"issue":"1","key":"10.1016\/j.anpede.2022.05.003_bib0025","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1159\/000486584","article-title":"Red blood cell transfusion in preterm infants: current evidence and controversies","volume":"114","author":"Howarth","year":"2018","journal-title":"Neonatology."},{"issue":"1","key":"10.1016\/j.anpede.2022.05.003_bib0030","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.tmrv.2021.07.005","article-title":"Regional oxygenation and perfusion monitoring to optimize neonatal packed red blood cell transfusion practices: a systematic review","volume":"36","author":"Jani","year":"2022","journal-title":"Transfus Med Rev."},{"key":"10.1016\/j.anpede.2022.05.003_bib0035","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2021.644462","article-title":"Anemia and red blood cell transfusions, cerebral oxygenation, brain injury and development, and neurodevelopmental outcome in preterm infants: a systematic review","volume":"9","author":"Kalteren","year":"2021","journal-title":"Front Pediatr."},{"issue":"2","key":"10.1016\/j.anpede.2022.05.003_bib0040","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S1696-2818(10)70013-5","article-title":"Anemia neonatal","volume":"8","author":"Bonastre-Blanco","year":"2010","journal-title":"An Pediatr\u00eda Contin."},{"issue":"5","key":"10.1016\/j.anpede.2022.05.003_bib0045","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/bjh.14233","article-title":"Guidelines on transfusion for fetuses, neonates and older children","volume":"175","author":"New","year":"2016","journal-title":"Br J Haematol."},{"issue":"2","key":"10.1016\/j.anpede.2022.05.003_bib0050","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1586\/17474086.2014.878225","article-title":"Management and prevention of neonatal anemia: current evidence and guidelines","volume":"7","author":"von Lindern","year":"2014","journal-title":"Expert Rev Hematol."},{"issue":"3","key":"10.1016\/j.anpede.2022.05.003_bib0055","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1159\/000365135","article-title":"Evidence-based advances in transfusion practice in neonatal intensive care units","volume":"106","author":"Christensen","year":"2014","journal-title":"Neonatology."},{"key":"10.1016\/j.anpede.2022.05.003_bib0060","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.1055\/s-0039-1691775","article-title":"Updates in red blood cell and platelet transfusions in preterm neonates","volume":"36","author":"Lopriore","year":"2019","journal-title":"Am J Perinatol."},{"issue":"3","key":"10.1016\/j.anpede.2022.05.003_bib0065","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2020-0576","article-title":"International liaison committee on resuscitation neonatal life support task force. Umbilical cord management for newborns <34 weeks\u2019 gestation: a meta-analysis","volume":"147","author":"Seidler","year":"2021","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.anpede.2022.05.003_bib0070","doi-asserted-by":"crossref","DOI":"10.1001\/jamapediatrics.2021.0102","article-title":"Association of umbilical cord management strategies with outcomes of preterm infants: a systematic review and network meta-analysis","volume":"175","author":"Jasani","year":"2021","journal-title":"JAMA Pediatr."},{"issue":"6","key":"10.1016\/j.anpede.2022.05.003_bib0075","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1136\/archdischild-2019-318627","article-title":"Umbilical cord milking in preterm infants: a systematic review and meta-analysis","volume":"105","author":"Balasubramanian","year":"2020","journal-title":"Arch Dis Child Fetal Neonatal Ed."},{"issue":"10","key":"10.1016\/j.anpede.2022.05.003_bib0080","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1001\/jamapediatrics.2020.2271","article-title":"Preterm erythropoietin neuroprotection trial consortium. Effect of high-dose erythropoietin on blood transfusions in extremely low gestational age neonates: post hoc analysis of a randomized clinical trial","volume":"174","author":"Juul","year":"2020","journal-title":"JAMA Pediatr."},{"issue":"5","key":"10.1016\/j.anpede.2022.05.003_bib0085","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2016-4317","article-title":"Prophylactic early erythropoietin for neuroprotection in preterm infants: a meta-analysis","volume":"139","author":"Fischer","year":"2017","journal-title":"Pediatrics."},{"issue":"3","key":"10.1016\/j.anpede.2022.05.003_bib0090","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/j.1365-2141.2012.09180.x","article-title":"The safety and efficacy of red cell transfusions in neonates: a systematic review of randomized controlled trials","volume":"158","author":"Venkatesh","year":"2012","journal-title":"Br J Haematol."},{"issue":"11","key":"10.1016\/j.anpede.2022.05.003_bib0095","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1055\/s-0036-1586106","article-title":"Neonatal transfusion practice: when do neonates need red blood cells or platelets?","volume":"33","author":"Del Vecchio","year":"2016","journal-title":"Am J Perinatol"},{"issue":"27","key":"10.1016\/j.anpede.2022.05.003_bib0100","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.1056\/NEJMoa2020248","article-title":"Higher or lower hemoglobin transfusion thresholds for preterm infants","volume":"383","author":"Kirpalani","year":"2020","journal-title":"N Engl J Med."},{"issue":"9","key":"10.1016\/j.anpede.2022.05.003_bib0105","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1001\/jama.2016.1204","article-title":"Association of red blood cell transfusion, anemia, and necrotizing enterocolitis in very low-birth-weight infants","volume":"315","author":"Patel","year":"2016","journal-title":"JAMA."},{"issue":"6","key":"10.1016\/j.anpede.2022.05.003_bib0110","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1542\/peds.2004-1884","article-title":"Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants","volume":"115","author":"Bell","year":"2005","journal-title":"Pediatrics."},{"issue":"4","key":"10.1016\/j.anpede.2022.05.003_bib0115","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1080\/09297049.2010.544647","article-title":"Neurocognitive profiles of preterm infants randomly assigned to lower or higher hematocrit thresholds for transfusion","volume":"17","author":"McCoy","year":"2011","journal-title":"Child Neuropsychol."},{"issue":"3","key":"10.1016\/j.anpede.2022.05.003_bib0120","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.jpeds.2006.05.011","article-title":"The Premature Infants in Need of Transfusion (PINT) study: a randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely low birth weight infants","volume":"149","author":"Kirpalani","year":"2006","journal-title":"J Pediatr."},{"issue":"2","key":"10.1016\/j.anpede.2022.05.003_bib0125","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/jpc.12409","article-title":"Restrictive versus liberal red blood cell transfusion thresholds in very low birth weight infants: a systematic review and meta-analysis","volume":"50","author":"Ibrahim","year":"2014","journal-title":"J Paediatr Child Health."},{"issue":"1","key":"10.1016\/j.anpede.2022.05.003_bib0130","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1542\/peds.2008-0338","article-title":"Neurodevelopmental outcome of extremely low birth weight infants randomly assigned to restrictive or liberal hemoglobin thresholds for blood transfusion","volume":"123","author":"Whyte","year":"2009","journal-title":"Pediatrics."},{"issue":"6","key":"10.1016\/j.anpede.2022.05.003_bib0135","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1001\/jama.2020.10690","article-title":"Effects of liberal vs restrictive transfusion thresholds on survival and neurocognitive outcomes in extremely low-birth-weight infants: the ETTNO randomized clinical trial","volume":"324","author":"Franz","year":"2020","journal-title":"JAMA."},{"issue":"2","key":"10.1016\/j.anpede.2022.05.003_bib0140","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/j.1537-2995.2010.02823.x","article-title":"Implementing a program to improve compliance with neonatal intensive care unit transfusion guidelines was accompanied by a reduction in transfusion rate: a pre-post analysis within a multihospital health care system","volume":"51","author":"Baer","year":"2011","journal-title":"Transfusion."},{"issue":"3","key":"10.1016\/j.anpede.2022.05.003_bib0145","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/s41372-018-0306-5","article-title":"To transfuse or not transfuse a premature infant: the new complex question","volume":"39","author":"Aucott","year":"2019","journal-title":"J Perinatol."},{"key":"10.1016\/j.anpede.2022.05.003_bib0150","series-title":"Patient blood management guidelines: module 6 neonatal and paediatrics","author":"Australian National Blood Authority","year":"2016"},{"key":"10.1016\/j.anpede.2022.05.003_bib0155","series-title":"In: Canadian Blood services, clinical guide to transfusion","article-title":"Chapter 13: neonatal and pediatrics transfusion","author":"Lau","year":"2017"},{"issue":"3","key":"10.1016\/j.anpede.2022.05.003_bib0160","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.clp.2015.04.005","article-title":"Reference intervals in neonatal hematology","volume":"42","author":"Henry","year":"2015","journal-title":"Clin Perinatol."},{"issue":"10","key":"10.1016\/j.anpede.2022.05.003_bib0165","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1080\/17474086.2019.1657824","article-title":"Platelet and red cell transfusions for neonates: lifesavers or Trojan horses?","volume":"12","author":"Fustolo-Gunnink","year":"2019","journal-title":"Expert Rev Hematol."},{"issue":"1","key":"10.1016\/j.anpede.2022.05.003_bib0170","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cll.2020.10.002","article-title":"Transfusion in neonatal patients: review of evidence-based guidelines","volume":"41","author":"Zerra","year":"2021","journal-title":"Clin Lab Med."},{"issue":"3","key":"10.1016\/j.anpede.2022.05.003_bib0175","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1056\/NEJMoa1807320","article-title":"Randomized trial of platelet-transfusion thresholds in neonates","volume":"380","author":"Curley","year":"2019","journal-title":"N Engl J Med."},{"issue":"26","key":"10.1016\/j.anpede.2022.05.003_bib0180","doi-asserted-by":"crossref","first-page":"2354","DOI":"10.1182\/blood.2019000899","article-title":"Preterm neonates benefit from low prophylactic platelet transfusion threshold despite varying risk of bleeding or death","volume":"134","author":"Fustolo-Gunnink","year":"2019","journal-title":"Blood."},{"issue":"3","key":"10.1016\/j.anpede.2022.05.003_bib0185","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.clp.2015.04.015","article-title":"Neonatal platelet function","volume":"42","author":"Del Vecchio","year":"2015","journal-title":"Clin Perinatol."},{"issue":"4","key":"10.1016\/j.anpede.2022.05.003_bib0190","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/bjh.12095","article-title":"How we decide when a neonate needs a transfusion","volume":"160","author":"Venkatesh","year":"2013","journal-title":"Br J Haematol."},{"issue":"3","key":"10.1016\/j.anpede.2022.05.003_bib0195","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.clp.2015.04.013","article-title":"Fresh frozen plasma administration in the neonatal intensive care unit: evidence-based guidelines","volume":"42","author":"Motta","year":"2015","journal-title":"Clin Perinatol."},{"issue":"5","key":"10.1016\/j.anpede.2022.05.003_bib0200","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1182\/blood.V72.5.1651.1651","article-title":"Development of the human coagulation system in the healthy premature infant","volume":"72","author":"Andrew","year":"1988","journal-title":"Blood."}],"container-title":["Anales de Pediatr\u00eda (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2341287922001387?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2341287922001387?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T09:44:49Z","timestamp":1762422289000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2341287922001387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S2341287922001387"],"URL":"https:\/\/doi.org\/10.1016\/j.anpede.2022.05.003","relation":{},"ISSN":["2341-2879"],"issn-type":[{"value":"2341-2879","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recommendations for transfusion of blood products in neonatology","name":"articletitle","label":"Article Title"},{"value":"Anales de Pediatr\u00eda (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anpede.2022.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.anpedi.2022.05.004","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Asociaci\u00f3n Espa\u00f1ola de Pediatr\u00eda. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}