{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:22:57Z","timestamp":1714004577029},"reference-count":25,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anales de Pediatr\u00eda (English Edition)"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.anpede.2024.03.011","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T15:38:05Z","timestamp":1711640285000},"page":"259-267","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["The paradigm of total body irradiation in acute lymphoblastic leukaemia: Therapeutic effectiveness versus the challenges of toxicity"],"prefix":"10.1016","volume":"100","author":[{"given":"Carlos","family":"Echecopar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismael","family":"del Val Rey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edctor","family":"Gal\u00e1n-G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Gonz\u00e1lez-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmina","family":"Mozo del Castillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berta","family":"Gonz\u00e1lez Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"P\u00e9rez-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.anpede.2024.03.011_bib0005","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/j.bbmt.2009.07.004","article-title":"Defining the intensity of conditioning regimens: working definitions","volume":"15","author":"Bacigalupo","year":"2009","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.anpede.2024.03.011_bib0010","doi-asserted-by":"crossref","first-page":"903","DOI":"10.3390\/curroncol28010089","article-title":"Total Body Irradiation for Hematopoietic Stem Cell Transplantation: What Can We Agree on?","volume":"28","author":"Sabloff","year":"2021","journal-title":"Curr Oncol"},{"key":"10.1016\/j.anpede.2024.03.011_bib0015","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1200\/JCO.20.02529","article-title":"Total body irradiation or chemotherapy conditioning in childhood ALL: A multinational, randomized, noninferiority phase III study","volume":"39","author":"Peters","year":"2021","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.anpede.2024.03.011_bib0020","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.radonc.2020.10.032","article-title":"Towards homogenization of total body irradiation practices in pediatric patients across SIOPE affiliated centers. A survey by the SIOPE radiation oncology working group","volume":"155","author":"Hoeben","year":"2021","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.anpede.2024.03.011_bib0025","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1016\/j.bbmt.2020.07.020","volume":"26","author":"Rodr\u00edguez-Arbol\u00ed","year":"2020","journal-title":"Biol Blood Marrow Transplant."},{"key":"10.1016\/j.anpede.2024.03.011_bib0030","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.anpedi.2018.05.023","article-title":"Neoplasias malignas secundarias despu\u00e9s de un trasplante de progenitores hematopoy\u00e9ticos en edad pedi\u00e1trica","volume":"90","author":"Sisinni","year":"2019","journal-title":"An Pediatr"},{"key":"10.1016\/j.anpede.2024.03.011_bib0035","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1038\/bmt.2016.139","article-title":"Incidence and severity of crucial late effects after allogeneic HSCT for malignancy under the age of 3 years: TBI is what really matters","volume":"51","author":"Bresters","year":"2016","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.anpede.2024.03.011_bib0040","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.radonc.2022.05.027","article-title":"ESTRO ACROP and SIOPE recommendations for myeloablative Total Body Irradiation in children","volume":"173","author":"Hoeben","year":"2022","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.anpede.2024.03.011_bib0045","doi-asserted-by":"crossref","first-page":"e616","DOI":"10.14694\/EdBook_AM.2015.35.e616","article-title":"The past, present, and future of patient-reported outcomes in oncology","author":"Strong","year":"2015","journal-title":"Am Soc Clin Oncol Educ Book"},{"key":"10.1016\/j.anpede.2024.03.011_bib0050","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1182\/blood.2019003858","article-title":"Patient-reported outcomes in survivors of childhood hematologic malignancies with hematopoietic stem cell transplant","volume":"135","author":"Yen","year":"2020","journal-title":"Blood."},{"key":"10.1016\/j.anpede.2024.03.011_bib0055","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2021.708906","article-title":"Pulmonary toxicity after total body irradiation - critical review of the literature and recommendations for toxicity reporting","volume":"11","author":"Vogel","year":"2021","journal-title":"Front Oncol."},{"key":"10.1016\/j.anpede.2024.03.011_bib0060","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1159\/000495698","article-title":"Diabetes and metabolic syndrome in survivors of childhood cancer","volume":"91","author":"Friedman","year":"2019","journal-title":"Horm Res Paediatr"},{"key":"10.1016\/j.anpede.2024.03.011_bib0065","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s12185-010-0611-z","article-title":"Late effects and quality of life of childhood cancer survivors: Part 2. Impact of radiotherapy","volume":"92","author":"Ishida","year":"2010","journal-title":"Int J Hematol"},{"key":"10.1016\/j.anpede.2024.03.011_bib0070","first-page":"vdaa122","article-title":"Risk factors associated with tinnitus in 2948 Dutch survivors of childhood cancer: a Dutch LATER questionnaire study","volume":"2","author":"Meijer","year":"2020","journal-title":"Neurooncol Adv"},{"key":"10.1016\/j.anpede.2024.03.011_bib0075","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1200\/JCO.20.02327","article-title":"Addressing neurocognitive late effects in pediatric cancer survivors: Current approaches and future opportunities","volume":"39","author":"Hocking","year":"2021","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.anpede.2024.03.011_bib0080","doi-asserted-by":"crossref","first-page":"2350","DOI":"10.1200\/JCO.20.01687","article-title":"Predictors of cognitive performance among infants treated for brain tumors: Findings from a multisite, prospective, longitudinal trial","volume":"39","author":"Ali","year":"2021","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.anpede.2024.03.011_bib0085","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.28894","article-title":"Female reproductive function after treatment of childhood acute lymphoblastic leukemia","volume":"68","author":"Roshandel","year":"2021","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.anpede.2024.03.011_bib0090","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/0360-3016(90)90248-I","article-title":"Second primary tumors following radiotherapy for childhood cancer","volume":"19","author":"Hawkins","year":"1990","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.anpede.2024.03.011_bib0095","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1038\/s41409-018-0337-8","article-title":"Long-term health outcomes in survivors of childhood AML treated with allogeneic HSCT: a NOPHO-AML Study","volume":"54","author":"Wilhelmsson","year":"2019","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.anpede.2024.03.011_bib0100","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20190829","article-title":"An update on effects of ionizing radiation exposure on the eye","volume":"93","author":"Hamada","year":"2020","journal-title":"Br J Radiol"},{"key":"10.1016\/j.anpede.2024.03.011_bib0105","doi-asserted-by":"crossref","first-page":"51","DOI":"10.4158\/EP12115.OR","article-title":"Severe insulin resistance and hypertriglyceridemia after childhood total body irradiation","volume":"19","author":"Mayson","year":"2013","journal-title":"Endocr Prac"},{"key":"10.1016\/j.anpede.2024.03.011_bib0110","doi-asserted-by":"crossref","first-page":"704","DOI":"10.3389\/fpsyg.2017.00704","article-title":"Long-term effects of haematopoietic stem cell transplantation after pediatric cancer: A qualitative analysis of life experiences and adaptation strategies","volume":"8","author":"Lahaye","year":"2017","journal-title":"Front Psychol"},{"key":"10.1016\/j.anpede.2024.03.011_bib0115","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1038\/s41409-018-0337-8","article-title":"Long-term health outcomes in survivors of childhood AML treated with allogeneic HSCT: a NOPHO\u2013AML Study","volume":"54","author":"Wilhelmsson","year":"2019","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.anpede.2024.03.011_bib0120","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1038\/s41375-022-01693-z","article-title":"Incidence of secondary malignancies after total body irradiation-based allogeneic HSCT in children with ALL \u2013 long-term follow-up from the prospective ALL-SCT 2003 trial","volume":"36","author":"Eichinger","year":"2022","journal-title":"Leukemia"},{"key":"10.1016\/j.anpede.2024.03.011_bib0125","doi-asserted-by":"crossref","first-page":"e812","DOI":"10.1097\/HS9.0000000000000812","article-title":"Reduced 8-Gray compared to standard 12-Gray total body irradiation for allogeneic transplantation in first remission acute lymphoblastic leukemia: A study of the acute leukemia working party of the EBMT","volume":"7","author":"Spyridonidis","year":"2023","journal-title":"HemaSphere"}],"container-title":["Anales de Pediatr\u00eda (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2341287924000632?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2341287924000632?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T11:22:49Z","timestamp":1713957769000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2341287924000632"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S2341287924000632"],"URL":"https:\/\/doi.org\/10.1016\/j.anpede.2024.03.011","relation":{},"ISSN":["2341-2879"],"issn-type":[{"value":"2341-2879","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The paradigm of total body irradiation in acute lymphoblastic leukaemia: Therapeutic effectiveness versus the challenges of toxicity","name":"articletitle","label":"Article Title"},{"value":"Anales de Pediatr\u00eda (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anpede.2024.03.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.anpedi.2024.01.008","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Asociaci\u00f3n Espa\u00f1ola de Pediatr\u00eda. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}