{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:12:02Z","timestamp":1793304722420,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,4,13]],"date-time":"2019-04-13T00:00:00Z","timestamp":1555113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anales de Pediatr\u00eda"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.anpedi.2018.12.019","type":"journal-article","created":{"date-parts":[[2019,5,20]],"date-time":"2019-05-20T17:30:16Z","timestamp":1558373416000},"page":"13-20","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Anomal\u00edas cong\u00e9nitas card\u00edacas en la Comunitat Valenciana 2007-2014, el registro poblacional de anomal\u00edas cong\u00e9nitas"],"prefix":"10.1016","volume":"92","author":[{"given":"Mar\u00eda","family":"Pastor-Garc\u00eda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Gimeno-Martos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d3scar","family":"Zurriaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 V.","family":"Sorl\u00ed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Cavero-Carbonell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anpedi.2018.12.019_bib0150","unstructured":"OMS: Organizaci\u00f3n Mundial de la Salud [en l\u00ednea]. Ginebra: OMS; 2007. [consultado 31 Oct 2016]. Disponible en: http:\/\/www.who.int\/mediacentre\/factsheets\/fs370\/en\/.."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0155","unstructured":"Hogan D, Liu L, Mathers C, Oza S, Chu Y. Methods and data sources for child causes of death 2000-2015. OMS [en l\u00ednea]. 2016. [consultado 31 Oct 2016]. Disponible en: http:\/\/www.who.int\/healthinfo\/global_burden_disease\/ChildCOD_method_2000_2015.pdf.."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0160","doi-asserted-by":"crossref","first-page":"58","DOI":"10.13189\/ujph.2014.020204","article-title":"Congenital anomalies: Prevalence and risk factors","volume":"2","author":"Francine","year":"2014","journal-title":"Univers J Public Health"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0165","unstructured":"EUROCAT. Prevalence Data Tables [en l\u00ednea]. 2017. [consultado 4 Nov 2016]. Disponible en: http:\/\/www.eurocat-network.eu\/newprevdata\/showPDF.aspx?winx=1256&winy=673&file=allsubgroups.aspx.."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0170","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/ejhg.2011.246","article-title":"Rare chromosome abnormalities, prevalence and prenatal diagnosis rates from population- based congenital anomaly registers in Europe","volume":"20","author":"Wellesley","year":"2012","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0175","first-page":"73","article-title":"Informe de vigilancia epidemiol\u00f3gica de anomal\u00edas cong\u00e9nitas en Espa\u00f1a sobre los datos registrados por el ECEMC en el per\u00edodo 1980-2011","author":"Bermejo-S\u00e1nchez","year":"2011","journal-title":"ECEMC."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0180","unstructured":"Revista de Dismorfolog\u00eda y Epidemiolog\u00eda. Anexo S\u00edndromes Identificados [en l\u00ednea]. Fundacion1000. 2014. [consultado 4 Nov 2016]. Disponible en: http:\/\/www.fundacion1000.es\/IMG\/pdf\/Boletin_Anexo_Sindromes_identificados.pdf.."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0185","doi-asserted-by":"crossref","unstructured":"Dolk H, Loane M, Garne E. Congenital heart defects in europe: prevalence and perinatal mortality, 2000 to 2005. Circulation. 2011; 123: 841-49.","DOI":"10.1161\/CIRCULATIONAHA.110.958405"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0190","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1136\/heartjnl-2012-302543","article-title":"Prevalence, timing of diagnosis and mortality of newborns with congenital heart defects: a population-based study","volume":"98","author":"Khoshnood","year":"2012","journal-title":"Heart."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0195","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1053\/j.pcsu.2010.02.005","article-title":"The challenge of congenital heart disease worldwide: Epidemiologic and demographic facts","volume":"13","author":"Bernier","year":"2010","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0200","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/chd.12176","article-title":"Temporal variation of birth prevalence of congenital heart disease in the United States","volume":"10","author":"Egbe","year":"2014","journal-title":"Congenit Heart Dis"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0205","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1007\/s00246-014-0921-7","article-title":"Changing prevalence of severe congenital heart disease: a population-based study","volume":"35","author":"Egbe","year":"2014","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0210","unstructured":"EUROCAT. Perinatal Mortality Associated with Congenital Anomalies in EUROCAT Full Member Registries, 2008-2012, by Type of Anomaly. [en l\u00ednea]. 2017. [consultado 2 Dic 2016]Disponible en: http:\/\/www.eurocat-network.eu\/content\/EUROCAT-Perinatal-Mortality-Table-1v.pdf.."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0215","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1016\/j.jacc.2011.08.025","article-title":"Birth prevalence of congenital heart disease worldwide. A systematic review and meta-analysis","volume":"58","author":"Van der Linde","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0220","unstructured":"Countries\/Registries, Anomalies, Years and Data [en l\u00ednea]. Eurocat-network.eu. 2017. [consultado 5 Abr 2017]. Disponible en: http:\/\/www.eurocat- network.eu\/accessprevalencedata\/prevalencetables ?.."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0225","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1161\/CIRCULATIONAHA.116.023370","article-title":"Congenital heart disease epidemiology in the United States","volume":"134","author":"KrasuskiR","year":"2016","journal-title":"Circulation."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0230","unstructured":"Burns P. Comunicaci\u00f3n Interauricular [en l\u00ednea]. Cove Point Foundation Johns Hopkins Children's Hospital. 2017. [consultado 24 Mar 2017].Disponible en: http:\/\/www.pted.org\/?id=sp\/atrialseptal3."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0235","unstructured":"Foramen oval permeable [en l\u00ednea]. Fundaciondelcorazon.com. 2015. [consultado 24 Mar 2017].Disponible en: http:\/\/www.fundaciondelcorazon.com\/informacion-para-pacientes\/enfermedades-cardiovasculares\/foramen-oval-permeable.html."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0240","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1046\/j.1469-0705.2001.00385.x","article-title":"Evaluation of prenatal diagnosis of congenital heart diseases by ultrasound: experience from 20 European registries","volume":"17","author":"Garne","year":"2001","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0245","series-title":"Congenital Heart Disease in Adolescents and Adults","author":"Schwerzmann","year":"2017"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0250","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1097\/OGX.0000000000000394","article-title":"Ultrasound examination of the fetal heart","volume":"72","author":"Bishop","year":"2017","journal-title":"Obstet Gynecol Surv"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0255","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1017\/S1047951114001887","article-title":"Maternal hypothyroidism may be associated with ACC in Offspring","volume":"25","author":"Grattan","year":"2015","journal-title":"Cardiol Young."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0260","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/14767050400028642","article-title":"Obstetric and neonatal out comes associated with maternal hypothyroid disease","volume":"17","author":"Wolfberg","year":"2005","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0265","doi-asserted-by":"crossref","unstructured":"Grattan MJ, Thomas DS, Hornberger LK, Hamilton RM, Midodzi WK, Vohra S. Maternal hypothyroidism may be associated with CHD in offspring. Cardiol Young. 2015; 25: 1247-53.","DOI":"10.1017\/S1047951114001887"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0270","doi-asserted-by":"crossref","first-page":"e833","DOI":"10.1542\/peds.2005-0397","article-title":"Cardiovascular malformations among preterm infants","volume":"116","author":"Tanner","year":"2005","journal-title":"Pediatrics."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0275","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004905.pub4","article-title":"Multiple-micronutrient supplementation for women during pregnancy","volume":"1","author":"Haider","year":"2015","journal-title":"Cochrane Database Syst Rev."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0280","unstructured":"Sobre el CSIC [en l\u00ednea]. Csic.es. 2017. [consultado 2 Dic 2016]. Disponible en: http:\/\/www.csic.es\/presentacion"},{"key":"10.1016\/j.anpedi.2018.12.019_bib0285","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ejmg.2014.12.002","article-title":"Associated non cardiac congenital anomalies among cases with congenital heart defects","volume":"58","author":"Stoll","year":"2015","journal-title":"Eur J Med Genet."},{"key":"10.1016\/j.anpedi.2018.12.019_bib0290","first-page":"159","article-title":"Non cardiac malformations in congenital heart disease: a retrospective analysis of 305 pediatric autopsies","volume":"47","author":"G\u00fc\u00e7er","year":"2005","journal-title":"Turk J Pediatr."}],"container-title":["Anales de Pediatr\u00eda"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1695403319301687?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1695403319301687?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:49:59Z","timestamp":1761662999000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1695403319301687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["S1695403319301687"],"URL":"https:\/\/doi.org\/10.1016\/j.anpedi.2018.12.019","relation":{},"ISSN":["1695-4033"],"issn-type":[{"value":"1695-4033","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anomal\u00edas cong\u00e9nitas card\u00edacas en la Comunitat Valenciana 2007-2014, el registro poblacional de anomal\u00edas cong\u00e9nitas","name":"articletitle","label":"Article Title"},{"value":"Anales de Pediatr\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anpedi.2018.12.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Asociaci\u00f3n Espa\u00f1ola de Pediatr\u00eda. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}