{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T23:10:16Z","timestamp":1759533016144,"version":"build-2065373602"},"reference-count":43,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annales de Chirurgie Plastique Esth\u00e9tique"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.anplas.2016.03.007","type":"journal-article","created":{"date-parts":[[2016,5,10]],"date-time":"2016-05-10T18:43:49Z","timestamp":1462905829000},"page":"439-449","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hypospadias"],"prefix":"10.1016","volume":"61","author":[{"given":"N.","family":"Boudaoud","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Pons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.-A.","family":"Bouche Pillon Persyn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Lefebvre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.-L.","family":"Poli Merol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Francois","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.anplas.2016.03.007_bib0220","first-page":"413","article-title":"The origin and fate of the urethral plate in man","volume":"88","author":"Glenister","year":"1954","journal-title":"J Anat"},{"issue":"3","key":"10.1016\/j.anplas.2016.03.007_bib0225","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0022-5347(05)67861-5","article-title":"Hypospadias urethral development","volume":"163","author":"Baskin","year":"2000","journal-title":"J Urol"},{"issue":"12","key":"10.1016\/j.anplas.2016.03.007_bib0230","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/S0022-3468(88)80322-1","article-title":"Pathogenesis of hypospadias\u00a0\u2013\u00a0more questions than answers","volume":"23","author":"Kluth","year":"1988","journal-title":"J Pediatr Surg"},{"issue":"4","key":"10.1016\/j.anplas.2016.03.007_bib0235","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.juro.2014.09.108","article-title":"Canalization of the urethral plate precedes fusion of the urethral folds during male penile urethral development: the double zipper hypothesis","volume":"193","author":"Li","year":"2015","journal-title":"J Urol"},{"issue":"4","key":"10.1016\/j.anplas.2016.03.007_bib0240","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1111\/j.1464-410X.2006.06435.x","article-title":"Gene expression profiles in mouse urethral development","volume":"98","author":"Li","year":"2006","journal-title":"BJU Int"},{"key":"10.1016\/j.anplas.2016.03.007_bib0245","first-page":"165","article-title":"Disorders of sex development: advances in genetic diagnosis and challenges in management","volume":"5","author":"Kyriakou","year":"2015","journal-title":"Adv Genom Genet"},{"issue":"3","key":"10.1016\/j.anplas.2016.03.007_bib0250","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1093\/humupd\/dms002","article-title":"Aetiology of hypospadias: a systematic review of genes and environment","volume":"18","author":"Van der Zanden","year":"2012","journal-title":"Hum Reprod Update"},{"issue":"4","key":"10.1016\/j.anplas.2016.03.007_bib0255","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.jpurol.2009.11.007","article-title":"Genetic pathway of external genitalia formation and molecular etiology of hypospadias","volume":"6","author":"Kojima","year":"2010","journal-title":"J Pediatr Urol"},{"year":"2000","series-title":"Epidemiology of male reproductive disorders","author":"Giwercman","key":"10.1016\/j.anplas.2016.03.007_bib0260"},{"issue":"8420","key":"10.1016\/j.anplas.2016.03.007_bib0265","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0140-6736(85)91999-3","article-title":"Trends in congenital malformations of external genitalia","volume":"1","author":"Matlai","year":"1985","journal-title":"Lancet"},{"issue":"Suppl.\u00a01","key":"10.1016\/j.anplas.2016.03.007_bib0270","first-page":"S31","article-title":"Paper 4: EUROCAT statistical monitoring: identification and investigation of ten year trends of congenital anomalies in Europe. Birth defects research Part A","volume":"91","author":"Loane","year":"2011","journal-title":"Clin Mol Teratol"},{"issue":"1","key":"10.1016\/j.anplas.2016.03.007_bib0275","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jpurol.2009.05.005","article-title":"Rising hypospadias rates: disproving a myth","volume":"6","author":"Fisch","year":"2010","journal-title":"J Pediatr Urol"},{"key":"10.1016\/j.anplas.2016.03.007_bib0280","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1289\/ehp.99107297","article-title":"International trends in rates of hypospadias and cryptorchidism","volume":"107","author":"Paulozzi","year":"1999","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.anplas.2016.03.007_bib0285","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1093\/humupd\/7.3.282","article-title":"Trends in the incidence of cryptorchidism and hypospadias, and methodological limitations of registry-based data","volume":"7","author":"Toppari","year":"2001","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.anplas.2016.03.007_bib0290","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1136\/adc.2006.112862","article-title":"Increasing prevalence of hypospadias in Western Australia, 1980\u20132000","volume":"92","author":"Nassar","year":"2007","journal-title":"Arch Dis Child"},{"issue":"7","key":"10.1016\/j.anplas.2016.03.007_bib0295","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1093\/humrep\/det111","article-title":"International geographic correlation study of the prevalence of disorders of male reproductive health","volume":"28","author":"Serrano","year":"2013","journal-title":"Hum Reprod"},{"issue":"11","key":"10.1016\/j.anplas.2016.03.007_bib0300","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1136\/archdischild-2015-308809","article-title":"Prevalence, repairs and complications of hypospadias: an Australian population-based study","volume":"100","author":"Schneuer","year":"2015","journal-title":"Arch Dis Child"},{"issue":"1","key":"10.1016\/j.anplas.2016.03.007_bib0305","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1745-7262.2007.00243.x","article-title":"Hypospadias: an update","volume":"9","author":"Leung","year":"2007","journal-title":"Asian J Androl"},{"issue":"12","key":"10.1016\/j.anplas.2016.03.007_bib0310","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1007\/s00345-015-1507-6","article-title":"Epidemiology of hypospadias in Europe: a registry-based study","volume":"33","author":"Bergman","year":"2015","journal-title":"World J Urol"},{"key":"10.1016\/j.anplas.2016.03.007_bib0315","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/aje\/kwm317","article-title":"Familial aggregation of hypospadias: a cohort study","volume":"167","author":"Schnack","year":"2008","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.anplas.2016.03.007_bib0320","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.1093\/humrep\/dem217","article-title":"Increased frequency of reproductive health problems among fathers of boys with hypospadias","volume":"22","author":"Asklund","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.anplas.2016.03.007_bib0325","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00439-002-0799-y","article-title":"Complex segregation analysis of hypospadias","volume":"111","author":"Fredell","year":"2002","journal-title":"Hum Genet"},{"key":"10.1016\/j.anplas.2016.03.007_bib0330","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1651-2227.1979.tb05060.x","article-title":"Male hypospadias, 625\u00a0cases, associated malformations and possible etiological factors","volume":"68","author":"Svensson","year":"1979","journal-title":"Acta Paediatr Scand"},{"issue":"1","key":"10.1016\/j.anplas.2016.03.007_bib0335","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jpurol.2014.10.003","article-title":"Environmental, parental and gestational factors that influence the occurrence of hypospadias in male patients","volume":"11","author":"Marrocco","year":"2015","journal-title":"J Pediatr Urol"},{"issue":"2","key":"10.1016\/j.anplas.2016.03.007_bib0340","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.mce.2011.01.006","article-title":"Hypospadias: interactions between environment and genetics","volume":"335","author":"Kalfa","year":"2011","journal-title":"Mol Cell Endocrinol"},{"issue":"2","key":"10.1016\/j.anplas.2016.03.007_bib0345","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jpurol.2010.11.009","article-title":"Hypospadias dilemmas: a round table","volume":"7","author":"Snodgrass","year":"2011","journal-title":"J Pediatr Urol"},{"issue":"Suppl.\u00a01","key":"10.1016\/j.anplas.2016.03.007_bib0350","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/S0929-693X(13)71403-9","article-title":"How and when to evaluate hypospadias?","volume":"20","author":"Bouvattier","year":"2013","journal-title":"Arch Pediatr"},{"key":"10.1016\/j.anplas.2016.03.007_bib0355","article-title":"Faut\u2013il \u00e9largir les indications de bilans hormonaux n\u00e9onataux d\u2019hypospade?","author":"Haraux","year":"2015","journal-title":"SFCP"},{"key":"10.1016\/j.anplas.2016.03.007_bib0360","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1542\/peds.97.4.590","article-title":"Timing of elective surgery on the genitalia of male children with particular reference to the risks, benefits, and psycho-logical effects of surgery and anesthesia","volume":"97","author":"Kass","year":"1996","journal-title":"Pediatrics"},{"issue":"6\u00a0Suppl.\u00a01","key":"10.1016\/j.anplas.2016.03.007_bib0365","first-page":"35","article-title":"Le traitement androg\u00e9nique avant la chirurgie d\u2019hypospade augmente-t-il le risque de complications li\u00e9es \u00e0 la cicatrisation\u00a0?","volume":"98","author":"Gorduza","year":"2010","journal-title":"Arch Pediatrie"},{"issue":"322","key":"10.1016\/j.anplas.2016.03.007_bib0370","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.morpho.2014.04.027","article-title":"Hypospadias\u00a0: comment l\u2019\u00e9volution des connaissances anatomiques \u00e0 travers les si\u00e8cles a-t-elle influenc\u00e9 les techniques de r\u00e9paration chirurgicale\u00a0?","volume":"98","author":"Mouttalib","year":"2014","journal-title":"Morphologie"},{"key":"10.1016\/j.anplas.2016.03.007_bib0375","first-page":"1","article-title":"Chirurgie des hypospades","author":"Mure","year":"2011"},{"issue":"3","key":"10.1016\/j.anplas.2016.03.007_bib0380","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.jpedsurg.2005.11.059","article-title":"Hypospadias: anatomy, etiology, and technique","volume":"41","author":"Baskin","year":"2006","journal-title":"J Pediatr Surg"},{"issue":"2","key":"10.1016\/j.anplas.2016.03.007_bib0385","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.jpurol.2010.05.001","article-title":"Surgical antibiotic practices among pediatric urologists in the United States","volume":"7","author":"Hsieh","year":"2011","journal-title":"J Pediatr Urol"},{"issue":"4\u00a0Suppl.","key":"10.1016\/j.anplas.2016.03.007_bib0390","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/j.juro.2013.02.015","article-title":"Is there a role for prophylactic antibiotics after stented hypospadias repair?","volume":"190","author":"Kanaroglou","year":"2013","journal-title":"J Urol"},{"issue":"7\u20138","key":"10.1016\/j.anplas.2016.03.007_bib0395","doi-asserted-by":"crossref","first-page":"236","DOI":"10.5489\/cuaj.1838","article-title":"The role of preoperative prophylactic antibiotics in hypospadias repair","volume":"8","author":"Baillargeon","year":"2014","journal-title":"Can Urol Assoc J"},{"issue":"2","key":"10.1016\/j.anplas.2016.03.007_bib0400","doi-asserted-by":"crossref","first-page":"241","DOI":"10.4103\/0970-1591.40622","article-title":"Acute postoperative complications of hypospadias repair","volume":"24","author":"Bhat","year":"2008","journal-title":"Indian J Urol"},{"issue":"12","key":"10.1016\/j.anplas.2016.03.007_bib0405","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/j.bjps.2015.07.024","article-title":"Fistula after single-stage primary hypospadias repair\u00a0\u2013\u00a0A systematic review of the literature","volume":"68","author":"Hardwicke","year":"2015","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"4\u00a0Pt 2","key":"10.1016\/j.anplas.2016.03.007_bib0410","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1016\/S0022-5347(06)00600-8","article-title":"Long-term cosmetic and sexual outcome of hypospadias surgery: norm-related study in adolescence","volume":"176","author":"Moriya","year":"2006","journal-title":"J Urol"},{"key":"10.1016\/j.anplas.2016.03.007_bib0415","first-page":"121","article-title":"Evaluation of cosmetic results in uncomplicated distal hypospadias repairs","volume":"16","author":"Castagnetti","year":"2009","journal-title":"J Androl Sci"},{"key":"10.1016\/j.anplas.2016.03.007_bib0420","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1016\/S0022-5347(01)66823-X","article-title":"Psychosexual adjustment of children and adolescents after different types of hypospadias surgery: a norm-related study","volume":"154","author":"Mureau","year":"1995","journal-title":"J Urol"},{"key":"10.1016\/j.anplas.2016.03.007_bib0425","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/S0022-5347(01)66859-9","article-title":"Psychosexual adjustment of men who underwent hypospadias repair: a norm-related study","volume":"154","author":"Mureau","year":"1995","journal-title":"J Urol"},{"issue":"5","key":"10.1016\/j.anplas.2016.03.007_bib0215","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1093\/jpepsy\/jsm098","article-title":"Psychosocial adjustment, health-related quality of life, and psychosexual development of boys with hypospadias: a systematic review","volume":"33","author":"Sch\u00f6nbucher","year":"2008","journal-title":"J Pediatr Psychol"}],"container-title":["Annales de Chirurgie Plastique Esth\u00e9tique"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0294126016300474?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0294126016300474?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:34:25Z","timestamp":1759530865000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0294126016300474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["S0294126016300474"],"URL":"https:\/\/doi.org\/10.1016\/j.anplas.2016.03.007","relation":{},"ISSN":["0294-1260"],"issn-type":[{"type":"print","value":"0294-1260"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypospadias","name":"articletitle","label":"Article Title"},{"value":"Annales de Chirurgie Plastique Esth\u00e9tique","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anplas.2016.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}