{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T14:21:51Z","timestamp":1774794111426,"version":"3.50.1"},"reference-count":43,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antiviral Research"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1016\/j.antiviral.2007.08.010","type":"journal-article","created":{"date-parts":[[2007,9,17]],"date-time":"2007-09-17T12:21:33Z","timestamp":1190031693000},"page":"6-13","source":"Crossref","is-referenced-by-count":14,"title":["Genetically delivered antibody protects against West Nile virus"],"prefix":"10.1016","volume":"77","author":[{"given":"Alexander","family":"Pereboev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktoriya","family":"Borisevich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Tsuladze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikhail","family":"Shakhmatov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Hudman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Kazachinskaia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Razumov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktor","family":"Svyatchenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valery","family":"Loktev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Yamshchikov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.antiviral.2007.08.010_bib1","first-page":"3081","article-title":"A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial","volume":"6","author":"Alvarez","year":"2000","journal-title":"Clin. Cancer. Res."},{"key":"10.1016\/j.antiviral.2007.08.010_bib2","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.ymthe.2004.06.865","article-title":"Therapeutic antibody gene transfer: an active approach to passive immunity","volume":"10","author":"Bakker","year":"2004","journal-title":"Mol. Ther."},{"key":"10.1016\/j.antiviral.2007.08.010_bib3","doi-asserted-by":"crossref","first-page":"13097","DOI":"10.1128\/JVI.76.24.13097-13100.2002","article-title":"Identification of neutralizing epitopes within structural domain III of the West Nile virus envelope protein","volume":"76","author":"Beasley","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1086\/376870","article-title":"Prophylactic and therapeutic efficacy of human intravenous immunoglobulin in treating West Nile virus infection in mice","volume":"188","author":"Ben-Nathan","year":"2003","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.antiviral.2007.08.010_bib5","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0378-1119(91)90244-6","article-title":"A surface expression vector for antibody screening","volume":"104","author":"Breitling","year":"1991","journal-title":"Gene"},{"key":"10.1016\/j.antiviral.2007.08.010_bib6","series-title":"Antibody Engineering","first-page":"41","article-title":"Construction of scFv from hybridoma by two-step cloning","author":"Breitling","year":"2001"},{"key":"10.1016\/j.antiviral.2007.08.010_bib7","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/sj.cgt.7700472","article-title":"A phase I\/II trial of rAd\/p53 (SCH 58500) gene replacement in recurrent ovarian cancer","volume":"9","author":"Buller","year":"2002","journal-title":"Cancer Gene Ther."},{"key":"10.1016\/j.antiviral.2007.08.010_bib8","doi-asserted-by":"crossref","first-page":"7769","DOI":"10.1128\/JVI.75.16.7769-7773.2001","article-title":"Monoclonal antibodies that bind to domain III of dengue virus E glycoprotein are the most efficient blockers of virus adsorption to Vero cells","volume":"75","author":"Crill","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib9","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1089\/088282403322396082","article-title":"Innate and adaptive immune responses determine protection against disseminated infection by West Nile encephalitis virus","volume":"16","author":"Diamond","year":"2003","journal-title":"Viral Immunol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0378-1119(93)90159-Z","article-title":"A family of vectors for surface display and production of antibodies","volume":"128","author":"Dubel","year":"1993","journal-title":"Gene"},{"key":"10.1016\/j.antiviral.2007.08.010_bib11","doi-asserted-by":"crossref","first-page":"12941","DOI":"10.1128\/JVI.77.24.12941-12949.2003","article-title":"Antibody prophylaxis and therapy against West Nile virus infection in wild-type and immunodeficient mice","volume":"77","author":"Engle","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib12","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/S0167-5699(97)01172-9","article-title":"FcRn: the MHC class I-related receptor that is more than an IgG transporter","volume":"18","author":"Ghetie","year":"1997","journal-title":"Immunol. Today"},{"key":"10.1016\/j.antiviral.2007.08.010_bib13","doi-asserted-by":"crossref","first-page":"14606","DOI":"10.1128\/JVI.79.23.14606-14613.2005","article-title":"Protective and therapeutic capacity of human single-chain Fv-Fc fusion proteins against West Nile virus","volume":"79","author":"Gould","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib14","doi-asserted-by":"crossref","first-page":"4178","DOI":"10.4049\/jimmunol.164.8.4178","article-title":"Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc","volume":"164","author":"Idusogie","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib15","doi-asserted-by":"crossref","first-page":"6179","DOI":"10.1158\/1078-0432.CCR-06-0746","article-title":"Gene therapy using adenovirus-mediated full-length anti-HER-2 antibody for HER-2 overexpression cancers","volume":"12","author":"Jiang","year":"2006","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.antiviral.2007.08.010_bib16","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.ymthe.2004.10.018","article-title":"Passive immunotherapy for anthrax toxin mediated by an adenovirus expressing an anti-protective antigen single-chain antibody","volume":"11","author":"Kasuya","year":"2005","journal-title":"Mol. Ther."},{"key":"10.1016\/j.antiviral.2007.08.010_bib17","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1002\/(SICI)1521-4141(199909)29:09<2819::AID-IMMU2819>3.0.CO;2-6","article-title":"Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn","volume":"29","author":"Kim","year":"1999","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib18","series-title":"Antibody Engineering","first-page":"137","article-title":"Immunotube selection","author":"Kontermann","year":"2001"},{"key":"10.1016\/j.antiviral.2007.08.010_bib19","doi-asserted-by":"crossref","first-page":"12931","DOI":"10.1128\/JVI.77.24.12931-12940.2003","article-title":"Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge","volume":"77","author":"Korokhov","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib20","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1093\/protein\/11.6.495","article-title":"High level expression and secretion of Fc-X fusion proteins in mammalian cells","volume":"11","author":"Lo","year":"1998","journal-title":"Protein Eng."},{"key":"10.1016\/j.antiviral.2007.08.010_bib21","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.4049\/jimmunol.147.8.2657","article-title":"Human Fc gamma RI and Fc gamma RII interact with distinct but overlapping sites on human IgG","volume":"147","author":"Lund","year":"1991","journal-title":"J. Immunol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib22","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3201\/eid0604.000408","article-title":"Isolation of two strains of West Nile virus during an outbreak in southern Russia, 1999","volume":"6","author":"Lvov","year":"2000","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.antiviral.2007.08.010_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0042-6822(68)90121-9","article-title":"The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12","volume":"36","author":"Maizel","year":"1968","journal-title":"Virology"},{"key":"10.1016\/j.antiviral.2007.08.010_bib24","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3181\/00379727-77-18884","article-title":"Isolation from human sera in Egypt of a virus apparently identical to West Nile virus","volume":"77","author":"Melnick","year":"1951","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.antiviral.2007.08.010_bib25","doi-asserted-by":"crossref","unstructured":"NIH report, 2002. Adenoviral vector safety and toxicity. Human Gene Ther. 13 (special issue).","DOI":"10.1089\/10430340152712610"},{"key":"10.1016\/j.antiviral.2007.08.010_bib26","doi-asserted-by":"crossref","first-page":"11467","DOI":"10.1128\/JVI.01125-06","article-title":"Crystal structure of the West Nile virus envelope glycoprotein","volume":"80","author":"Nybakken","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib27","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/nm1240","article-title":"Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus","volume":"11","author":"Oliphant","year":"2005","journal-title":"Nat. Med."},{"key":"10.1016\/j.antiviral.2007.08.010_bib28","doi-asserted-by":"crossref","first-page":"12149","DOI":"10.1128\/JVI.01732-06","article-title":"Antibody recognition and neutralization determinants on domains I and II of West Nile virus envelope protein","volume":"80","author":"Oliphant","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib29","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/BF01310983","article-title":"Passive immunization of mice with monoclonal antibodies raised against tick-borne encephalitis virus. Brief report","volume":"93","author":"Phillpotts","year":"1987","journal-title":"Arch. Virol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib30","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1086\/375247","article-title":"Development of a cocktail of recombinant-expressed human rabies virus-neutralizing monoclonal antibodies for postexposure prophylaxis of rabies","volume":"188","author":"Prosniak","year":"2003","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.antiviral.2007.08.010_bib31","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/S0020-7519(03)00063-8","article-title":"Traditional and novel approaches to flavivirus vaccines","volume":"33","author":"Pugachev","year":"2003","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib32","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1089\/vim.2005.18.558","article-title":"Neutralizing monoclonal antibodies against Russian strain of the West Nile virus","volume":"18","author":"Razumov","year":"2005","journal-title":"Viral. Immunol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib33","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/j.1749-6632.2001.tb02704.x","article-title":"Antibody prophylaxis and therapy for flavivirus encephalitis infections","volume":"951","author":"Roehrig","year":"2001","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1016\/j.antiviral.2007.08.010_bib34","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.virol.2005.02.020","article-title":"Characterization of neutralizing antibodies to West Nile virus","volume":"336","author":"Sanchez","year":"2005","journal-title":"Virology"},{"key":"10.1016\/j.antiviral.2007.08.010_bib35","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.4049\/jimmunol.135.4.2805","article-title":"Protection against 17D yellow fever encephalitis in mice by passive transfer of monoclonal antibodies to the nonstructural glycoprotein gp48 and by active immunization with gp48","volume":"135","author":"Schlesinger","year":"1985","journal-title":"J. Immunol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib36","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1128\/JCM.38.6.2232-2239.2000","article-title":"Evaluation of immunoglobulin M (IgM) and IgG enzyme immunoassays in serologic diagnosis of West Nile virus infection","volume":"38","author":"Tardei","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib37","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3201\/eid0803.010238","article-title":"Immunization with heterologous flaviviruses protective against fatal West Nile encephalitis","volume":"8","author":"Tesh","year":"2002","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.antiviral.2007.08.010_bib38","doi-asserted-by":"crossref","first-page":"6982","DOI":"10.1128\/JVI.00551-06","article-title":"Isolation and characterization of human monoclonal antibodies from individuals infected with West Nile virus","volume":"80","author":"Throsby","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib39","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.jmb.2007.02.024","article-title":"Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tract","volume":"368","author":"Wu","year":"2007","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib40","doi-asserted-by":"crossref","first-page":"4364","DOI":"10.1128\/JVI.71.6.4364-4371.1997","article-title":"Upregulation of signalase processing and induction of prM-E secretion by the flavivirus NS2B-NS3 protease: roles of protease components","volume":"71","author":"Yamshchikov","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2007.08.010_bib41","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.virol.2004.09.014","article-title":"An attenuated West Nile prototype virus is highly immunogenic and protects against the deadly NY99 strain: a candidate for live WN vaccine development","volume":"330","author":"Yamshchikov","year":"2004","journal-title":"Virology"},{"key":"10.1016\/j.antiviral.2007.08.010_bib42","doi-asserted-by":"crossref","first-page":"4785","DOI":"10.1016\/j.vaccine.2005.04.036","article-title":"The suitability of yellow fever and Japanese encephalitis vaccines for immunization against West Nile virus","volume":"23","author":"Yamshchikov","year":"2005","journal-title":"Vaccine"},{"key":"10.1016\/j.antiviral.2007.08.010_bib43","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1158\/0008-5472.CAN-06-3641","article-title":"Establishment of a new interleukin-6 (IL-6) receptor inhibitor applicable to the gene therapy for IL-6-dependent tumor","volume":"67","author":"Yoshio-Hoshino","year":"2007","journal-title":"Cancer Res."}],"container-title":["Antiviral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166354207004020?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166354207004020?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,14]],"date-time":"2023-05-14T04:43:44Z","timestamp":1684039424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166354207004020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["S0166354207004020"],"URL":"https:\/\/doi.org\/10.1016\/j.antiviral.2007.08.010","relation":{},"ISSN":["0166-3542"],"issn-type":[{"value":"0166-3542","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}