{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T05:39:10Z","timestamp":1773812350681,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antiviral Research"],"published-print":{"date-parts":[[2011,7]]},"DOI":"10.1016\/j.antiviral.2011.04.016","type":"journal-article","created":{"date-parts":[[2011,5,8]],"date-time":"2011-05-08T00:37:43Z","timestamp":1304815063000},"page":"64-71","source":"Crossref","is-referenced-by-count":11,"title":["Inhibition of rabies virus propagation in mouse neuroblastoma cells by an intrabody against the viral phosphoprotein"],"prefix":"10.1016","volume":"91","author":[{"given":"Yoshihiro","family":"Kaku","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Noguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kozue","family":"Hotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akio","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.antiviral.2011.04.016_b0005","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1038\/335395a0","article-title":"Gene therapy. Intracellular immunization","volume":"335","author":"Baltimore","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.antiviral.2011.04.016_b0010","doi-asserted-by":"crossref","first-page":"7957","DOI":"10.1038\/sj.onc.1205931","article-title":"Rabies virus P and small P products interact directly with PML and reorganize PML nuclear bodies","volume":"21","author":"Blondel","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.antiviral.2011.04.016_b0015","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1590\/S1413-86702007000200011","article-title":"Short-interfering RNAs as antivirals against rabies","volume":"11","author":"Brandao","year":"2007","journal-title":"Braz. J. Infect. Dis."},{"key":"10.1016\/j.antiviral.2011.04.016_b0020","first-page":"227","article-title":"Intracellular antibodies (intrabodies) versus RNA interference for therapeutic applications","volume":"35","author":"Cao","year":"2005","journal-title":"Ann. Clin. Lab. Sci."},{"key":"10.1016\/j.antiviral.2011.04.016_b0025","doi-asserted-by":"crossref","first-page":"10808","DOI":"10.1128\/JVI.00977-09","article-title":"Peptides that mimic the amino-terminal end of the rabies virus phosphoprotein have antiviral activity","volume":"83","author":"Castel","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0030","doi-asserted-by":"crossref","first-page":"2889","DOI":"10.1099\/0022-1317-75-11-2889","article-title":"In vivo interaction of rabies virus phosphoprotein (P) and nucleoprotein (N): existence of two N-binding sites on P protein","volume":"75","author":"Chenik","year":"1994","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0035","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1128\/JVI.72.3.1925-1930.1998","article-title":"Mapping the interacting domains between the rabies virus polymerase and phosphoprotein","volume":"72","author":"Chenik","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0040","doi-asserted-by":"crossref","first-page":"3797","DOI":"10.1182\/blood-2005-04-1627","article-title":"Intrabodies targeting the Kaposi sarcoma-associated herpesvirus latency antigen inhibit viral persistence in lymphoma cells","volume":"106","author":"Corte-Real","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.antiviral.2011.04.016_b0045","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nrm1129","article-title":"Killing the messenger: short RNAs that silence gene expression","volume":"4","author":"Dykxhoorn","year":"2003","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0050","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/j.jmb.2009.03.061","article-title":"Modular organization of rabies virus phosphoprotein","volume":"388","author":"Gerard","year":"2009","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0055","doi-asserted-by":"crossref","first-page":"32036","DOI":"10.1074\/jbc.M201906200","article-title":"Functional neutralization of HIV-1 Vif protein by intracellular immunization inhibits reverse transcription and viral replication","volume":"277","author":"Goncalves","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.antiviral.2011.04.016_b0060","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1080\/13550280600902295","article-title":"Failure of therapeutic coma and ketamine for therapy of human rabies","volume":"12","author":"Hemachudha","year":"2006","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0065","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.antiviral.2009.07.012","article-title":"Inhibition of rabies virus replication by multiple artificial microRNAs","volume":"84","author":"Israsena","year":"2009","journal-title":"Antiviral Res."},{"key":"10.1016\/j.antiviral.2011.04.016_b0070","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1128\/JVI.69.2.1044-1049.1995","article-title":"Intracellular interference of tick-borne flavivirus infection by using a single-chain antibody fragment delivered by recombinant Sindbis virus","volume":"69","author":"Jiang","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0075","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1002\/hep.22366","article-title":"Specific targeting of hepatitis C virus core protein by an intracellular single-chain antibody of human origin","volume":"48","author":"Karthe","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.antiviral.2011.04.016_b0080","doi-asserted-by":"crossref","first-page":"8745","DOI":"10.1128\/JVI.77.16.8745-8755.2003","article-title":"Stable high-producer cell clone expressing virus-like particles of the Japanese encephalitis virus e protein for a second-generation subunit vaccine","volume":"77","author":"Kojima","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0085","doi-asserted-by":"crossref","first-page":"7948","DOI":"10.1128\/JVI.00554-09","article-title":"Functional characterization of Negri bodies (NBs) in rabies virus-infected cells: evidence that NBs are sites of viral transcription and replication","volume":"83","author":"Lahaye","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0090","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/sj.gt.3300346","article-title":"Intrabodies: turning the humoral immune system outside in for intracellular immunization","volume":"4","author":"Marasco","year":"1997","journal-title":"Gene Ther."},{"key":"10.1016\/j.antiviral.2011.04.016_b0095","doi-asserted-by":"crossref","first-page":"115","DOI":"10.7883\/yoken.JJID.2005.115","article-title":"Detection of rabies-specific antigens by egg yolk antibody (IgY) to the recombinant rabies virus proteins produced in Escherichia coli","volume":"58","author":"Motoi","year":"2005","journal-title":"Jpn. J. Infect. Dis."},{"key":"10.1016\/j.antiviral.2011.04.016_b0100","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/1743-422X-6-73","article-title":"Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome","volume":"6","author":"Nawtaisong","year":"2009","journal-title":"Virol. J."},{"key":"10.1016\/j.antiviral.2011.04.016_b0105","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1592\/phco.29.10.1182","article-title":"Overview, prevention, and treatment of rabies","volume":"29","author":"Nigg","year":"2009","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.antiviral.2011.04.016_b0110","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1006\/jmbi.1999.2854","article-title":"Removal of the conserved disulfide bridges from the scFv fragment of an antibody: effects on folding kinetics and aggregation","volume":"290","author":"Ramm","year":"1999","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0115","first-page":"493","article-title":"A simple method of estimating fifty percent endpoints","volume":"27","author":"Reed","year":"1938","journal-title":"Am. J. Hyg."},{"key":"10.1016\/j.antiviral.2011.04.016_b0120","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/nrmicro2260","article-title":"The cell biology of rabies virus: using stealth to reach the brain","volume":"8","author":"Schnell","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0125","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1093\/nar\/gkp841","article-title":"Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents","volume":"38","author":"Stein","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.antiviral.2011.04.016_b0130","doi-asserted-by":"crossref","first-page":"3285","DOI":"10.1099\/vir.0.80075-0","article-title":"Effects of intrabodies specific for rotavirus NSP5 during the virus replicative cycle","volume":"85","author":"Vascotto","year":"2004","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0135","doi-asserted-by":"crossref","first-page":"4255","DOI":"10.1128\/JVI.01930-06","article-title":"The nucleocytoplasmic rabies virus P protein counteracts interferon signaling by inhibiting both nuclear accumulation and DNA binding of STAT1","volume":"81","author":"Vidy","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0140","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1056\/NEJMoa050382","article-title":"Survival after treatment of rabies with induction of coma","volume":"352","author":"Willoughby","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.antiviral.2011.04.016_b0145","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1006\/jmbi.2000.4265","article-title":"Stability engineering of antibody single-chain Fv fragments","volume":"305","author":"W\u00f6rn","year":"2001","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.antiviral.2011.04.016_b0150","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/hep.510300105","article-title":"Intracellular single-chain antibody against hepatitis B virus core protein inhibits the replication of hepatitis B virus in cultured cells","volume":"30","author":"Yamamoto","year":"1999","journal-title":"Hepatology"}],"container-title":["Antiviral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166354211002956?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166354211002956?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T15:48:49Z","timestamp":1712418529000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166354211002956"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["S0166354211002956"],"URL":"https:\/\/doi.org\/10.1016\/j.antiviral.2011.04.016","relation":{},"ISSN":["0166-3542"],"issn-type":[{"value":"0166-3542","type":"print"}],"subject":[],"published":{"date-parts":[[2011,7]]}}}