{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:59:16Z","timestamp":1791172756899,"version":"4.1.0"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"National Natural Scientific Foundation","award":["81370518"],"award-info":[{"award-number":["81370518"]}]},{"name":"National Programs for High Technology Research and Development of China","award":["SS2015AA020924"],"award-info":[{"award-number":["SS2015AA020924"]}]},{"name":"Ministry of Science and Technology of China","award":["2012CB518905"],"award-info":[{"award-number":["2012CB518905"]}]},{"name":"Ministry of Science and Technology of China","award":["2013ZX10004003"],"award-info":[{"award-number":["2013ZX10004003"]}]},{"name":"Ministry of Science and Technology of China","award":["SS2012AA020905"],"award-info":[{"award-number":["SS2012AA020905"]}]},{"DOI":"10.13039\/501100005090","name":"Beijing Nova Program","doi-asserted-by":"publisher","award":["Z141107001814054"],"award-info":[{"award-number":["Z141107001814054"]}],"id":[{"id":"10.13039\/501100005090","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Antiviral Research"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.antiviral.2015.06.015","type":"journal-article","created":{"date-parts":[[2015,6,23]],"date-time":"2015-06-23T01:55:33Z","timestamp":1435024533000},"page":"145-151","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Recombinant influenza virus carrying human adenovirus epitopes elicits protective immunity in mice"],"prefix":"10.1016","volume":"121","author":[{"given":"Penghui","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tieling","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjing","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peirui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaohai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaogeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiliang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.antiviral.2015.06.015_b0005","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.antiviral.2014.01.022","article-title":"Influenza virus vaccine expressing fusion and attachment protein epitopes of respiratory syncytial virus induces protective antibodies in BALB\/c mice","volume":"104","author":"Bian","year":"2014","journal-title":"Antiviral Res."},{"key":"10.1016\/j.antiviral.2015.06.015_b0010","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1128\/JCM.42.4.1686-1693.2004","article-title":"Molecular analysis of adenovirus isolates from vaccinated and unvaccinated young adults","volume":"42","author":"Blasiole","year":"2004","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.antiviral.2015.06.015_b0015","doi-asserted-by":"crossref","first-page":"e99322","DOI":"10.1371\/journal.pone.0099322","article-title":"Response of mice and ferrets to a monovalent influenza A (H7N9) split vaccine","volume":"9","author":"Duan","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.antiviral.2015.06.015_b0020","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.vetmic.2005.11.062","article-title":"The recombinant rabbit hemorrhagic disease virus VP60 protein obtained from Pichia pastoris induces a strong humoral and cell-mediated immune response following intranasal immunization in mice","volume":"114","author":"Farnos","year":"2006","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.antiviral.2015.06.015_b0025","doi-asserted-by":"crossref","first-page":"357","DOI":"10.2217\/fvl.11.6","article-title":"Implications of the innate immune response to adenovirus and adenoviral vectors","volume":"6","author":"Gregory","year":"2011","journal-title":"Future Virol."},{"key":"10.1016\/j.antiviral.2015.06.015_b0030","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/S0042-6822(03)00372-6","article-title":"Enhancement of mucosal immune responses by chimeric influenza HA\/SHIV virus-like particles","volume":"313","author":"Guo","year":"2003","journal-title":"Virology"},{"key":"10.1016\/j.antiviral.2015.06.015_b0035","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.vaccine.2011.11.046","article-title":"Sendai virus-based RSV vaccine protects African green monkeys from RSV infection","volume":"30","author":"Jones","year":"2012","journal-title":"Vaccine"},{"key":"10.1016\/j.antiviral.2015.06.015_b0040","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1186\/1743-422X-8-375","article-title":"Absence of vaccine-enhanced RSV disease and changes in pulmonary dendritic cells with adenovirus-based RSV vaccine","volume":"8","author":"Krause","year":"2011","journal-title":"Virology journal"},{"key":"10.1016\/j.antiviral.2015.06.015_b0045","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.vaccine.2008.10.032","article-title":"A recombinant replication-defective human adenovirus type 3: a vaccine candidate","volume":"27","author":"Li","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.antiviral.2015.06.015_b0050","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1006\/viro.2001.1008","article-title":"Reverse genetics of influenza virus","volume":"287","author":"Neumann","year":"2001","journal-title":"Virology"},{"key":"10.1016\/j.antiviral.2015.06.015_b0055","doi-asserted-by":"crossref","first-page":"2666","DOI":"10.1128\/JVI.78.6.2666-2673.2004","article-title":"Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors","volume":"78","author":"Sumida","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.antiviral.2015.06.015_b0060","doi-asserted-by":"crossref","first-page":"7179","DOI":"10.4049\/jimmunol.174.11.7179","article-title":"Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein","volume":"174","author":"Sumida","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.antiviral.2015.06.015_b0065","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.virusres.2013.08.013","article-title":"Epitope mapping and characterization of a neutralizing monoclonal antibody against human adenovirus type 3","volume":"177","author":"Tian","year":"2013","journal-title":"Virus Res."},{"key":"10.1016\/j.antiviral.2015.06.015_b0070","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/0264-410X(91)90055-B","article-title":"Efficacy of nucleoprotein and haemagglutinin antigens expressed in fowlpox virus as vaccine for influenza in chickens","volume":"9","author":"Webster","year":"1991","journal-title":"Vaccine"},{"key":"10.1016\/j.antiviral.2015.06.015_b0075","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.virusres.2014.01.027","article-title":"Construction and characterization of a recombinant human adenovirus type 3 vector containing two foreign neutralizing epitopes in hexon","volume":"183","author":"Xue","year":"2014","journal-title":"Virus Res."},{"key":"10.1016\/j.antiviral.2015.06.015_b0080","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.vaccine.2010.11.026","article-title":"Immunogenicity and protective efficacy of a live attenuated vaccine against the 2009 pandemic A H1N1 in mice and ferrets","volume":"29","author":"Yang","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.antiviral.2015.06.015_b0085","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.vaccine.2008.12.039","article-title":"Construction and characterization of a replication-competent human adenovirus type 3-based vector as a live-vaccine candidate and a viral delivery vector","volume":"27","author":"Zhang","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.antiviral.2015.06.015_b0090","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.1099\/vir.0.064105-0","article-title":"Characterization of recombinant influenza A virus as a vector expressing respiratory syncytial virus fusion protein epitopes","volume":"95","author":"Zhang","year":"2014","journal-title":"J. Gen. Virol."}],"container-title":["Antiviral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166354215001461?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166354215001461?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T11:21:31Z","timestamp":1537528891000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166354215001461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":18,"alternative-id":["S0166354215001461"],"URL":"https:\/\/doi.org\/10.1016\/j.antiviral.2015.06.015","relation":{},"ISSN":["0166-3542"],"issn-type":[{"value":"0166-3542","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recombinant influenza virus carrying human adenovirus epitopes elicits protective immunity in mice","name":"articletitle","label":"Article Title"},{"value":"Antiviral Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.antiviral.2015.06.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}