{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:07:52Z","timestamp":1791299272735,"version":"4.1.0"},"reference-count":13,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T00:00:00Z","timestamp":1485388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"European Union Research Programmes","award":["#66609"],"award-info":[{"award-number":["#66609"]}]},{"name":"European Union Research Programmes","award":["#653316"],"award-info":[{"award-number":["#653316"]}]},{"name":"EbolaMoDRAD, IMI","award":["#115843"],"award-info":[{"award-number":["#115843"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Antiviral Research"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.antiviral.2017.01.017","type":"journal-article","created":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T12:15:48Z","timestamp":1485432948000},"page":"95-105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Implementation of a non-human primate model of Ebola disease: Infection of Mauritian cynomolgus macaques and analysis of virus populations"],"prefix":"10.1016","volume":"140","author":[{"given":"G\u00e9raldine","family":"Piorkowski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4317-7688","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Jacquot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1897-8210","authenticated-orcid":false,"given":"Gilles","family":"Qu\u00e9rat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3910-9647","authenticated-orcid":false,"given":"Caroline","family":"Carbonnelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9517-7981","authenticated-orcid":false,"given":"Delphine","family":"Pannetier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"France","family":"Mentr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4241-3255","authenticated-orcid":false,"given":"Herv\u00e9","family":"Raoul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"de Lamballerie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.antiviral.2017.01.017_bib1","doi-asserted-by":"crossref","first-page":"S991","DOI":"10.1093\/infdis\/jir336","article-title":"Host response dynamics following lethal infection of rhesus macaques with Zaire ebolavirus","volume":"204","author":"Ebihara","year":"2011","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.antiviral.2017.01.017_bib2","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1093\/infdis\/166.4.753","article-title":"Pathogenic potential of filoviruses: role of geographic origin of primate host and virus strain","volume":"166","author":"Fisher-Hoch","year":"1992","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.antiviral.2017.01.017_bib3","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1093\/infdis\/152.5.887","article-title":"Pathophysiology of shock and hemorrhage in a fulminating viral infection (Ebola)","volume":"152","author":"Fisher-Hoch","year":"1985","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.antiviral.2017.01.017_bib4","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1016\/S0002-9440(10)63591-2","article-title":"Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection","volume":"163","author":"Geisbert","year":"2003","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.antiviral.2017.01.017_bib5","series-title":"Filovirus Pathogenesis in Nonhuman Primates","author":"Geisbert","year":"2002"},{"key":"10.1016\/j.antiviral.2017.01.017_bib6","doi-asserted-by":"crossref","first-page":"4125","DOI":"10.1128\/JCM.39.11.4125-4130.2001","article-title":"Development and evaluation of a fluorogenic 5\u2019 nuclease assay to detect and differentiate between Ebola virus subtypes Zaire and Sudan","volume":"39","author":"Gibb","year":"2001","journal-title":"J.\u00a0Clin. Microbiol."},{"key":"10.1016\/j.antiviral.2017.01.017_bib7","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1007\/s11427-015-4857-9","article-title":"Non-coding regions of the Ebola virus genome contain indispensable phylogenetic and evolutionary information","volume":"58","author":"Jiang","year":"2015","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.antiviral.2017.01.017_bib8","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/ajpa.1330960203","article-title":"Mitochondrial DNA of the Mauritian macaques (Macaca fascicularis): an example of the founder effect","volume":"96","author":"Lawler","year":"1995","journal-title":"Am. J. Phys. Anthropol."},{"key":"10.1016\/j.antiviral.2017.01.017_bib9","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.3201\/eid2110.150259","article-title":"Delayed disease progression in cynomolgus macaques infected with Ebola virus Makona strain","volume":"21","author":"Marzi","year":"2015","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.antiviral.2017.01.017_bib10","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2164-15-748","article-title":"Genetic substructure in cynomolgus macaques (Macaca fascicularis) on the island of Mauritius","volume":"15","author":"Ogawa","year":"2014","journal-title":"BMC Genomics"},{"key":"10.1016\/j.antiviral.2017.01.017_bib11","doi-asserted-by":"crossref","DOI":"10.1038\/srep03365","article-title":"Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb","volume":"3","author":"Qiu","year":"2013","journal-title":"Sci. Rep."},{"key":"10.1016\/j.antiviral.2017.01.017_bib12","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3003876","article-title":"Successful treatment of Ebola virus\u2013infected cynomolgus macaques with monoclonal antibodies","volume":"4","author":"Qiu","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.antiviral.2017.01.017_bib13","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.ympev.2006.08.002","article-title":"Comparative phylogenetics offer new insights into the biogeographic history of Macaca fascicularis and the origin of the Mauritian macaques","volume":"42","author":"Tosi","year":"2007","journal-title":"Mol. Phylogenet. Evol."}],"container-title":["Antiviral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016635421630537X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016635421630537X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T05:01:00Z","timestamp":1530075660000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016635421630537X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":13,"alternative-id":["S016635421630537X"],"URL":"https:\/\/doi.org\/10.1016\/j.antiviral.2017.01.017","relation":{},"ISSN":["0166-3542"],"issn-type":[{"value":"0166-3542","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Implementation of a non-human primate model of Ebola disease: Infection of Mauritian cynomolgus macaques and analysis of virus populations","name":"articletitle","label":"Article Title"},{"value":"Antiviral Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.antiviral.2017.01.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}