{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:40:17Z","timestamp":1792680017112,"version":"4.5.0"},"reference-count":65,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T00:00:00Z","timestamp":1556150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Hepatology"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.aohep.2019.04.007","type":"journal-article","created":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T00:11:13Z","timestamp":1557360673000},"page":"563-570","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Non-alcoholic fatty liver disease and neurological defects"],"prefix":"10.1016","volume":"18","author":[{"given":"Rita","family":"Moretti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Caruso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Gazzin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aohep.2019.04.007_bib0330","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/hep.24376","article-title":"Endpoints and clinical trial design for nonalcoholic steatohepatitits","volume":"54","author":"Sanyal","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.aohep.2019.04.007_bib0335","doi-asserted-by":"crossref","first-page":"g4596","DOI":"10.1136\/bmj.g4596","article-title":"Non alcoholic fatty liver disease","volume":"349","author":"Sattar","year":"2014","journal-title":"BMJ"},{"issue":"86","key":"10.1016\/j.aohep.2019.04.007_bib0340","first-page":"1136","article-title":"non alcoholic fatty liver disease is associated with cognitive function in adults","volume":"22","author":"Won Seo","year":"2016","journal-title":"Neurology"},{"issue":"37","key":"10.1016\/j.aohep.2019.04.007_bib0345","doi-asserted-by":"crossref","first-page":"13306","DOI":"10.3748\/wjg.v20.i37.13306","article-title":"Nonalcoholic fatty liver disease and vascular disease: state of the art","volume":"20","author":"Fargion","year":"2014","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.aohep.2019.04.007_bib0350","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1055\/s-0028-1091978","article-title":"The epidemiology of non alcoholic fatty liver disease: a global perspective","author":"Lazo","year":"2008","journal-title":"Semin Liver Dis"},{"key":"10.1016\/j.aohep.2019.04.007_bib0355","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.jhep.2010.04.008","article-title":"A position statement on NAFLD\/NASH based on the EASL 2009 special conference","volume":"53","author":"Ratziu","year":"2010","journal-title":"J Hepatol"},{"issue":"3","key":"10.1016\/j.aohep.2019.04.007_bib0360","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1177\/1756283X11430859","article-title":"Secondary causes of nonalcoholic fatty liver disease","volume":"5","author":"Kneeman","year":"2012","journal-title":"Therap Adv Gastroent"},{"issue":"12","key":"10.1016\/j.aohep.2019.04.007_bib0365","doi-asserted-by":"crossref","first-page":"99","DOI":"10.30699\/ijp.2017.25038","article-title":"Clinical manifestations and diagnosis of nonalcoholic fatty liver disease","volume":"82","author":"Khoonsari","year":"2017","journal-title":"Ir J Pathol"},{"key":"10.1016\/j.aohep.2019.04.007_bib0370","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.cgh.2011.12.039","article-title":"Independent association between non alcoholic fatty liver disease and cardiovascular disease in the US population","volume":"10","author":"Stepanova","year":"2012","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.aohep.2019.04.007_bib0375","first-page":"9","article-title":"Non alcoholic fatty liver disease and metabolic syndrome","volume":"13","author":"Paschos","year":"2009","journal-title":"Hyppokrata"},{"key":"10.1016\/j.aohep.2019.04.007_bib0380","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1056\/NEJMra0912063","article-title":"Risk of cardiovascular disease in patients with non alcoholic fatty liver disease","volume":"363","author":"Targher","year":"2010","journal-title":"N Engl J Med"},{"issue":"Suppl. 6","key":"10.1016\/j.aohep.2019.04.007_bib0385","first-page":"19S","article-title":"New cardiovascular risk factors: homocysteine and vitamins involved in homocysteine metabolism","volume":"5","author":"De Caterina","year":"2004","journal-title":"Ital Heart J"},{"key":"10.1016\/j.aohep.2019.04.007_bib0390","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1471-2261-6-38","article-title":"Homocysteine, vitamin B12 and folate levels in premature coronary artery disease","volume":"6","author":"Sadeghian","year":"2006","journal-title":"BMC Cardiovasc Disord"},{"issue":"4","key":"10.1016\/j.aohep.2019.04.007_bib0395","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jjcc.2012.11.009","article-title":"Vitamin B12 deficiency and hyperhomocysteinemia as correlates of cardiovascular risk factors in Indian subjects with coronary artery disease","volume":"61","author":"Mohan","year":"2013","journal-title":"J Cardiol"},{"key":"10.1016\/j.aohep.2019.04.007_bib0400","doi-asserted-by":"crossref","first-page":"40","DOI":"10.2174\/1874192401509010040","article-title":"Is vitamin d deficiency a new risk factor for cardiovascular disease?","volume":"9","author":"Mandarino","year":"2015","journal-title":"Open Cardiovasc Med J"},{"key":"10.1016\/j.aohep.2019.04.007_bib0405","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2017.00169","article-title":"Vitamin D, homocysteine, and folate in subcortical vascular dementia and Alzheimer dementia","author":"Moretti","year":"2017","journal-title":"Front Aging Neurosci"},{"key":"10.1016\/j.aohep.2019.04.007_bib0410","unstructured":"WHO, IDF. Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia. 2006. Geneva."},{"key":"10.1016\/j.aohep.2019.04.007_bib0415","doi-asserted-by":"crossref","first-page":"393","DOI":"10.3343\/alm.2013.33.6.393","article-title":"HbA1C: a review of analytical and clinical aspects","volume":"33","author":"Weykamp","year":"2013","journal-title":"Ann Lab Med"},{"key":"10.1016\/j.aohep.2019.04.007_bib0420","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge","volume":"18","author":"Friedwald","year":"1972","journal-title":"Clin Chem"},{"key":"10.1016\/j.aohep.2019.04.007_bib0425","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1093\/ageing\/afu093","article-title":"National osteoporosis society vitamin D guideline summary","volume":"43","author":"Aspray","year":"2014","journal-title":"Age Ageing"},{"key":"10.1016\/j.aohep.2019.04.007_bib0430","first-page":"9690","article-title":"The prevalence and etiology of elevated aminotransferase levels in the United States","volume":"98","author":"Clark","year":"2003","journal-title":"Am J Gastroentorol"},{"key":"10.1016\/j.aohep.2019.04.007_bib0435","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1002\/hep.510230513","article-title":"Prediction of risk of liver disease by alcohol intake, sex and age: a prospective population study","volume":"23","author":"Becker","year":"1996","journal-title":"Hepatology"},{"key":"10.1016\/j.aohep.2019.04.007_bib0440","doi-asserted-by":"crossref","first-page":"g4596","DOI":"10.1136\/bmj.g4596","article-title":"Non alcoholic fatty liver disease","volume":"349","author":"Sattar","year":"2014","journal-title":"BMJ"},{"key":"10.1016\/j.aohep.2019.04.007_bib0445","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1212\/WNL.55.11.1621","article-title":"Frontal Assessment Battery at bedside","volume":"55","author":"Dubois","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.aohep.2019.04.007_bib0450","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s10072-005-0443-4","article-title":"The Frontal Assessment Battery: normative values in an Italian population sample","volume":"26","author":"Apollonio","year":"2005","journal-title":"Neurol Sci"},{"key":"10.1016\/j.aohep.2019.04.007_bib0455","series-title":"Beck Depression Inventory-Second Edition. Manual","author":"Beck","year":"1996"},{"key":"10.1016\/j.aohep.2019.04.007_bib0460","series-title":"Beck Depression Inventory II: Manuale Italiano","author":"Ghisi","year":"2006"},{"key":"10.1016\/j.aohep.2019.04.007_bib0465","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.2044-8341.1959.tb00467.x","article-title":"The assessment of anxiety states by rating","volume":"32","author":"Hamilton","year":"1959","journal-title":"Br. J Med Psychol"},{"issue":"2","key":"10.1016\/j.aohep.2019.04.007_bib0470","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0165-1781(91)90040-V","article-title":"Reliability and validity of the apathy evaluation scale","volume":"38","author":"Marin","year":"1991","journal-title":"Psych Res"},{"key":"10.1016\/j.aohep.2019.04.007_bib0475","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1037\/h0054651","article-title":"Studies of interference in spatial and verbal reactions","volume":"18","author":"Stroop","year":"1935","journal-title":"J Exp Psychol"},{"key":"10.1016\/j.aohep.2019.04.007_bib0480","first-page":"945","article-title":"Test di Stroop: dati normative Italiani di una versione cartacea per l\u2019uso clinic","volume":"37","author":"Valgimigli","year":"2010","journal-title":"Giornale It Psicol"},{"key":"10.1016\/j.aohep.2019.04.007_bib0485","doi-asserted-by":"crossref","first-page":"3541","DOI":"10.2337\/diabetes.54.12.3541","article-title":"Non alcoholic fatty liver disease and risk of future cardiovascular events among type 2 diabetic patients","volume":"54","author":"Targher","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.aohep.2019.04.007_bib0490","doi-asserted-by":"crossref","first-page":"d6891","DOI":"10.1136\/bmj.d6891","article-title":"Non-alcoholic fatty liver disease and mortality among US adults: prospective cohort study","volume":"343","author":"Lazo","year":"2011","journal-title":"BMJ"},{"key":"10.1016\/j.aohep.2019.04.007_bib0495","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4172\/2161-1017.1000135","article-title":"Nonalcoholic fatty liver disease (NAFLD), a manifestation of the metabolic syndrome: new perspectives on the nutritional therapy","volume":"3","author":"de Piano","year":"2014","journal-title":"Endocrinol Metab Synd"},{"key":"10.1016\/j.aohep.2019.04.007_bib0500","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1038\/nature05487","article-title":"Mechanisms linking obesity with cardiovascular disease","volume":"444","author":"Van Gaal","year":"2006","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.aohep.2019.04.007_bib0505","doi-asserted-by":"crossref","first-page":"440","DOI":"10.3390\/nu10040440","article-title":"Folate and B12 levels correlate with histological severity in NASH patients","volume":"10","author":"Mahamid","year":"2018","journal-title":"Nutrients"},{"key":"10.1016\/j.aohep.2019.04.007_bib0510","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/1741-7015-9-85","article-title":"Strong association between non alcoholic fatty liver disease (NAFLD) and low 25(OH) vitamin D levels in an adult population with normal serum liver enzymes","volume":"9","author":"Barchetta","year":"2011","journal-title":"BMC Med"},{"key":"10.1016\/j.aohep.2019.04.007_bib0515","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1002\/hep.25930","article-title":"Liver vitamin D receptor, CYP2R1 and CYP27A1 expression: relationship with liver histology and vitamin D3 levels in patients with non alcoholic steatohepatis or hepatitis C virus","volume":"56","author":"Barchetta","year":"2012","journal-title":"Hepatology"},{"key":"10.1016\/j.aohep.2019.04.007_bib0520","doi-asserted-by":"crossref","first-page":"3180","DOI":"10.1161\/STROKEAHA.109.557280","article-title":"Carotid intimal medial thickness predicts cognitive decline among adults without clinical vascular disease","volume":"40","author":"Wendell","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.aohep.2019.04.007_bib0525","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/S0271-5317(00)80020-2","article-title":"Folate deficiency is associated with obesity and anemia in Mexican urban women","volume":"20","author":"Casanueva","year":"2000","journal-title":"Nutr Res"},{"key":"10.1016\/j.aohep.2019.04.007_bib0530","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.nut.2004.03.022","article-title":"Serum folate and homocysteine levels in obese females with non-alcoholic fatty liver","volume":"21","author":"Hirsch","year":"2005","journal-title":"Nutrition"},{"key":"10.1016\/j.aohep.2019.04.007_bib0535","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/hep.23280","article-title":"Obesity and nonalcoholic fatty liver disease: biochemical, metabolic and clinical implications","volume":"51","author":"Fabbrini","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.aohep.2019.04.007_bib0540","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1139\/cjpp-2016-0681","article-title":"Role of folate in nonalcoholic fatty liver disease","volume":"95","author":"Sid","year":"2017","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.aohep.2019.04.007_bib0545","article-title":"Serum folic acid levels are associated with the presence and severity of liver steatosis in Chinese adults","author":"Xia","year":"2017","journal-title":"Clin Nutr"},{"key":"10.1016\/j.aohep.2019.04.007_bib0550","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.2310\/JIM.0b013e31822a29f5","article-title":"Association between serum Vitamin B12 levels and the degree of steatosis in patients with nonalcoholic fatty liver disease","volume":"59","author":"Koplay","year":"2011","journal-title":"J Investig Med"},{"issue":"260","key":"10.1016\/j.aohep.2019.04.007_bib0555","article-title":"Association of serum Vitamin B12 levels with stage of liver fibrosis and treatment outcome in patients with chronic hepatitis C virus genotype 1 infection: a retrospective study","volume":"8","author":"Mechie","year":"2015","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.aohep.2019.04.007_bib0560","first-page":"179","article-title":"Use of serum Vitamin B12 level as a marker to differentiate idiopathic noncirrhotic intrahepatic portal hypertension from cryptogenic cirrhosis","volume":"58","author":"Goel","year":"2013","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.aohep.2019.04.007_bib0565","doi-asserted-by":"crossref","first-page":"659","DOI":"10.3109\/09637486.2011.649249","article-title":"Serum Vitamin B12 and folate levels in patients with non-alcoholic fatty liver disease","volume":"63","author":"Polyzos","year":"2012","journal-title":"Int J Food Sci Nutr"},{"key":"10.1016\/j.aohep.2019.04.007_bib0570","first-page":"203","article-title":"Association of Vitamin B12 with obesity, overweight, insulin resistance and metabolic syndrome, and body fat composition; primary care-based study","volume":"10","author":"Baltaci","year":"2013","journal-title":"Med Glas"},{"key":"10.1016\/j.aohep.2019.04.007_bib0575","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1111\/j.1440-1746.2005.03891.x","article-title":"Elevated plasma homocysteine concentrations as a predictor of steatohepatitis in patients with non-alcoholic fatty liver disease","volume":"20","author":"Gulsen","year":"2005","journal-title":"J Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.aohep.2019.04.007_bib0580","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S1665-2681(19)31488-7","article-title":"Serum homocysteine levels in patients with nonalcoholic fatty liver disease","volume":"11","author":"Polyzos","year":"2012","journal-title":"Ann Hepatol"},{"key":"10.1016\/j.aohep.2019.04.007_bib0585","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12974-015-0467-5","article-title":"Non-Alcoholic fatty liver disease induces signs of Alzheimer's disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD model","volume":"13","author":"Kim","year":"2016","journal-title":"J Neuroinflamm"},{"key":"10.1016\/j.aohep.2019.04.007_bib0590","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/hep.20781","article-title":"Endothelial dysfunction and cardiovascular risk profile in non alcoholic fatty liver disease","volume":"42","author":"Villanova","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.aohep.2019.04.007_bib0595","first-page":"1531","article-title":"Multimodal markers of inflammation in the subcortical ischemic vascular disease type of vascular cognitive impairment","volume":"45","author":"Rosenberg","year":"2014","journal-title":"Storke"},{"key":"10.1016\/j.aohep.2019.04.007_bib0600","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3389\/fnagi.2014.00171","article-title":"Systemic inflammation, blood brain barrier vulnerability and cognitive\/non cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapy","volume":"6","author":"Takeda","year":"2014","journal-title":"Front Aging Neurosci"},{"key":"10.1016\/j.aohep.2019.04.007_bib0605","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1097\/01.psy.0000221276.17823.df","article-title":"Depression, anxiety, and non alcoholic steatohepatitis","volume":"68","author":"Elwing","year":"2006","journal-title":"PSychosom Med"},{"key":"10.1016\/j.aohep.2019.04.007_bib0610","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.psym.2010.12.019","article-title":"Depression in patients with nonalcoholic fatty liver disease and chronic viral hepatitis B and C","volume":"52","author":"Weinstein","year":"2011","journal-title":"Psychosomatics"},{"key":"10.1016\/j.aohep.2019.04.007_bib0615","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1111\/liv.12165","article-title":"Associations of depression, anxiety and antidepressants with histological severity of nonalcoholic fatty liver disease","volume":"33","author":"Youssef","year":"2013","journal-title":"Liver Int"},{"key":"10.1016\/j.aohep.2019.04.007_bib0620","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/jgh.12897","article-title":"Non alcoholic fatty liver disease comorbid with major depressive disorder. The pathological features and poor therapeutic efficacy","volume":"30","author":"Tomeno","year":"2015","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.aohep.2019.04.007_bib0625","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3389\/fnagi.2016.00289","article-title":"Neural correlates for apathy: frontal\u2013prefrontal and parietal cortical\u2013subcortical circuits","volume":"8","author":"Moretti","year":"2016","journal-title":"Front Aging Neurosci"},{"key":"10.1016\/j.aohep.2019.04.007_bib0630","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.neuroimage.2011.05.012","article-title":"Influence of skin blood flow on near-infrared spectroscopy signals measured on the forehead during a verbal fluency task","volume":"57","author":"Takahashi","year":"2011","journal-title":"Neuroimage"},{"key":"10.1016\/j.aohep.2019.04.007_bib0635","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.neuroimage.2012.02.074","article-title":"The physiological origin of task-evoked systemic artifacts in functional near infrared spectroscopy","volume":"61","author":"Kirilina","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.aohep.2019.04.007_bib0640","unstructured":"National Guide Centre UK: Non Alcoholic fatty liver disease. Assessment and management. London National Institute for Health and Care Excellence (UK): 2016, July. Nice Guideline, no 49, 5, Risk factors for NAFLD."},{"key":"10.1016\/j.aohep.2019.04.007_bib0645","doi-asserted-by":"crossref","first-page":"15080","DOI":"10.1038\/nrdp.2015.80","article-title":"Non alcoholic fatty liver disease","volume":"1","author":"Brunt","year":"2015","journal-title":"Nat Rev Disease Primers"},{"issue":"10","key":"10.1016\/j.aohep.2019.04.007_bib0650","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.4254\/wjh.v7.i10.1369","article-title":"Non Alcoholic fatty liver disease: the heart of the matter","volume":"7","author":"Azzam","year":"2015","journal-title":"World J Hepatol"}],"container-title":["Annals of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1665268119300626?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1665268119300626?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,12,11]],"date-time":"2020-12-11T18:25:23Z","timestamp":1607711123000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1665268119300626"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":65,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["S1665268119300626"],"URL":"https:\/\/doi.org\/10.1016\/j.aohep.2019.04.007","relation":{},"ISSN":["1665-2681"],"issn-type":[{"value":"1665-2681","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Non-alcoholic fatty liver disease and neurological defects","name":"articletitle","label":"Article Title"},{"value":"Annals of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aohep.2019.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Fundaci\u00f3n Cl\u00ednica M\u00e9dica Sur, A.C. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}