{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T14:40:25Z","timestamp":1771339225115,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T00:00:00Z","timestamp":1566950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Hepatology"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.aohep.2019.08.002","type":"journal-article","created":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T08:37:37Z","timestamp":1567672657000},"page":"573-577","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Low-molecular-weight heparin followed by rivaroxaban for acute occlusive portomesenteric vein thrombosis in a cirrhotic patient treated with multiple endoscopic variceal procedures"],"prefix":"10.1016","volume":"19","author":[{"given":"Xiangbo","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaozhong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ran","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Le","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qianqian","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fangfang","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingshun","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.aohep.2019.08.002_bib0150","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1111\/jgh.14501","article-title":"Portal vein thrombosis prevalence and associated mortality in cirrhosis in a nationally representative inpatient cohort","volume":"34","author":"Cool","year":"2019","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0155","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.mehy.2010.12.007","article-title":"Occlusive portal vein thrombosis as a new marker of decompensated cirrhosis","volume":"76","author":"Qi","year":"2011","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.aohep.2019.08.002_bib0160","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/nrgastro.2014.36","article-title":"Management of portal vein thrombosis in liver cirrhosis","volume":"11","author":"Qi","year":"2014","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0165","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.mayocp.2013.01.012","article-title":"Mesenteric venous thrombosis","volume":"88","author":"Singal","year":"2013","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.aohep.2019.08.002_bib0170","doi-asserted-by":"crossref","unstructured":"EASL Clinical Practice Guidelines: vascular diseases of the liver. J Hepatol 2016;64:179\u2013202.","DOI":"10.1016\/j.jhep.2015.07.040"},{"key":"10.1016\/j.aohep.2019.08.002_bib0175","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.jhep.2015.05.022","article-title":"Expanding consensus in portal hypertension: report of the Baveno VI Consensus Workshop: stratifying risk and individualizing care for portal hypertension","volume":"63","author":"de Franchis","year":"2015","journal-title":"J Hepatol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0180","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1016\/j.cgh.2014.04.026","article-title":"Associations of coagulation factor V Leiden and prothrombin G20210A mutations with Budd-Chiari syndrome and portal vein thrombosis: a systematic review and meta-analysis","volume":"12","author":"Qi","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0185","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1097\/MEG.0000000000000056","article-title":"Prevalence of thrombotic risk factors in Chinese Budd-Chiari syndrome patients: results of a prospective validation study","volume":"26","author":"Qi","year":"2014","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0190","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/MEG.0000000000000221","article-title":"Thrombotic risk factors in Chinese nonmalignant and noncirrhotic patients with portal vein thrombosis: an observational study with a systematic review of the literature","volume":"27","author":"Qi","year":"2015","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"4","key":"10.1016\/j.aohep.2019.08.002_bib0195","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1007\/s12072-019-09951-6","article-title":"Nonselective beta-blockers and development of portal vein thrombosis in liver cirrhosis: a systematic review and meta-analysis","volume":"13","author":"Xu","year":"2019","journal-title":"Hepatol Int"},{"key":"10.1016\/j.aohep.2019.08.002_bib0200","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.cgh.2012.01.012","article-title":"Efficacy and safety of anticoagulation on patients with cirrhosis and portal vein thrombosis","volume":"10","author":"Delgado","year":"2012","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0205","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1111\/j.1478-3231.2012.02785.x","article-title":"Prospective evaluation of anticoagulation and transjugular intrahepatic portosystemic shunt for the management of portal vein thrombosis in cirrhosis","volume":"32","author":"Senzolo","year":"2012","journal-title":"Liver Int"},{"key":"10.1016\/j.aohep.2019.08.002_bib0210","doi-asserted-by":"crossref","first-page":"384","DOI":"10.3350\/cmh.2014.20.4.384","article-title":"Safety, efficacy, and response predictors of anticoagulation for the treatment of nonmalignant portal-vein thrombosis in patients with cirrhosis: a propensity score matching analysis","volume":"20","author":"Chung","year":"2014","journal-title":"Clin Mol Hepatol"},{"issue":"4","key":"10.1016\/j.aohep.2019.08.002_bib0215","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.clinre.2018.11.011","article-title":"Portal vein thrombosis and liver cirrhosis: long-term anticoagulation is effective and safe","volume":"43","author":"Bergere","year":"2019","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0220","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1097\/MEG.0000000000000351","article-title":"Efficacy and safety of anticoagulation therapy with different doses of enoxaparin for portal vein thrombosis in cirrhotic patients with hepatitis B","volume":"27","author":"Cui","year":"2015","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0225","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/MEG.0000000000000482","article-title":"Efficacy and safety of anticoagulation in more advanced portal vein thrombosis in patients with liver cirrhosis","volume":"28","author":"Chen","year":"2016","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0230","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s12916-018-1069-8","article-title":"Transient portal vein thrombosis in liver cirrhosis","volume":"16","author":"Qi","year":"2018","journal-title":"BMC Med"},{"key":"10.1016\/j.aohep.2019.08.002_bib0235","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ejim.2014.12.002","article-title":"Anticoagulation for the treatment of portal vein thrombosis in liver cirrhosis: a systematic review and meta-analysis of observational studies","volume":"26","author":"Qi","year":"2015","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.aohep.2019.08.002_bib0240","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1053\/j.gastro.2017.04.042","article-title":"Effects of anticoagulants in patients with cirrhosis and portal vein thrombosis: A systematic review and meta-analysis","volume":"153","author":"Loffredo","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1016\/j.aohep.2019.08.002_bib0245","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/s41395-018-0421-0","article-title":"Clinical impact and safety of anticoagulants for portal vein thrombosis in cirrhosis","volume":"114","author":"Pettinari","year":"2018","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0250","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.vph.2018.05.002","article-title":"Randomized controlled trial of rivaroxaban versus warfarin in the management of acute non-neoplastic portal vein thrombosis","volume":"113","author":"Hanafy","year":"2019","journal-title":"Vascul Pharmacol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0255","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1007\/s10620-015-4012-2","article-title":"Direct oral anticoagulants in cirrhosis patients pose similar risks of bleeding when compared to traditional anticoagulation","volume":"61","author":"Intagliata","year":"2016","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.aohep.2019.08.002_bib0260","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/ejh.12844","article-title":"The efficacy and safety of direct oral anticoagulants vs traditional anticoagulants in cirrhosis","volume":"98","author":"Hum","year":"2017","journal-title":"Eur J Haematol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0265","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.thromres.2018.08.011","article-title":"Direct oral anticoagulants in patients with liver cirrhosis: a systematic review","volume":"170","author":"Hoolwerf","year":"2018","journal-title":"Thromb Res"},{"key":"10.1016\/j.aohep.2019.08.002_bib0270","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/j.cgh.2017.10.016","article-title":"Harmful and beneficial effects of anticoagulants in patients with cirrhosis and portal vein thrombosis","volume":"16","author":"La Mura","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0275","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s12876-017-0668-8","article-title":"Portal vein thrombosis in liver cirrhosis: incidence, management, and outcome","volume":"17","author":"Fujiyama","year":"2017","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0280","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.gastrohep.2018.06.005","article-title":"Efficacy and safety of anticoagulation in non-malignant portal vein thrombosis in patients with liver cirrhosis","volume":"41","author":"Artaza","year":"2018","journal-title":"Gastroenterol Hepatol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0285","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/MCG.0b013e3181b3ab44","article-title":"Safety and efficacy of anticoagulation therapy with low molecular weight heparin for portal vein thrombosis in patients with liver cirrhosis","volume":"44","author":"Amitrano","year":"2010","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.aohep.2019.08.002_bib0290","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1007\/s10620-012-2548-y","article-title":"Portal vein thrombosis in patients with end stage liver disease awaiting liver transplantation: outcome of anticoagulation","volume":"58","author":"Werner","year":"2013","journal-title":"Dig Dis Sci"}],"container-title":["Annals of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1665268119322252?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1665268119322252?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:40:13Z","timestamp":1761648013000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1665268119322252"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S1665268119322252"],"URL":"https:\/\/doi.org\/10.1016\/j.aohep.2019.08.002","relation":{},"ISSN":["1665-2681"],"issn-type":[{"value":"1665-2681","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low-molecular-weight heparin followed by rivaroxaban for acute occlusive portomesenteric vein thrombosis in a cirrhotic patient treated with multiple endoscopic variceal procedures","name":"articletitle","label":"Article Title"},{"value":"Annals of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aohep.2019.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Fundaci\u00f3n Cl\u00ednica M\u00e9dica Sur, A.C. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}