{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T20:54:33Z","timestamp":1781643273960,"version":"3.54.5"},"reference-count":20,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2502800"],"award-info":[{"award-number":["2022YFC2502800"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81870642"],"award-info":[{"award-number":["81870642"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82371040"],"award-info":[{"award-number":["82371040"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81670835"],"award-info":[{"award-number":["81670835"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970780"],"award-info":[{"award-number":["81970780"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271069"],"award-info":[{"award-number":["82271069"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470613"],"award-info":[{"award-number":["81470613"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82122017"],"award-info":[{"award-number":["82122017"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82301188"],"award-info":[{"award-number":["82301188"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","award":["20254Y0085"],"award-info":[{"award-number":["20254Y0085"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018625","name":"Science and Technology Innovation Plan Of Shanghai Science and Technology Commission","doi-asserted-by":"publisher","award":["21S31904900"],"award-info":[{"award-number":["21S31904900"]}],"id":[{"id":"10.13039\/501100018625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018625","name":"Science and Technology Innovation Plan Of Shanghai Science and Technology Commission","doi-asserted-by":"publisher","award":["23Y11909800"],"award-info":[{"award-number":["23Y11909800"]}],"id":[{"id":"10.13039\/501100018625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014137","name":"Shanghai Shenkang Hospital Development Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014137","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advances in Ophthalmology Practice and Research"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.aopr.2025.12.002","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T16:33:07Z","timestamp":1769013187000},"page":"139-145","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Swept-source OCTA assessment of iris vasculature as a biomarker for myopic macular degeneration severity"],"prefix":"10.1016","volume":"6","author":[{"given":"Kang","family":"Ching","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiwen","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenwen","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keke","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangjia","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.aopr.2025.12.002_bib1","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1136\/bjophthalmol-2020-316930","article-title":"Anterior segment optical coherence tomography angiography for iris vasculature in pigmented eyes","volume":"105","author":"Ang","year":"2021","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"10.1016\/j.aopr.2025.12.002_bib2","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.aopr.2024.06.003","article-title":"Complications of high myopia: an update from clinical manifestations to underlying mechanisms","volume":"4","author":"Du","year":"2024","journal-title":"Adv Ophthalmol Pract Res"},{"key":"10.1016\/j.aopr.2025.12.002_bib3","doi-asserted-by":"crossref","DOI":"10.7189\/jogh.12.04026","article-title":"A systematic review of clinical practice guidelines for myopic macular degeneration","volume":"12","author":"Chen","year":"2022","journal-title":"J Glob Health"},{"key":"10.1016\/j.aopr.2025.12.002_bib4","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.preteyeres.2018.10.005","article-title":"Myopic maculopathy: current status and proposal for a new classification and grading system (ATN)","volume":"69","author":"Ruiz-Medrano","year":"2019","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.aopr.2025.12.002_bib5","article-title":"Quantitative assessment of the choroidal vasculature in myopic macular degeneration with optical coherence tomographic angiography","volume":"3","author":"Dan","year":"2023","journal-title":"Front Ophthalmol (Lausanne)"},{"issue":"18","key":"10.1016\/j.aopr.2025.12.002_bib6","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1038\/s41433-024-03321-9","article-title":"Morphologic features of iris in highly myopic eyes based on a novel swept-source optical coherence tomography","volume":"38","author":"Kang","year":"2024","journal-title":"Eye (Lond)"},{"issue":"5","key":"10.1016\/j.aopr.2025.12.002_bib7","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1038\/s41433-021-01809-2","article-title":"Imaging of iris vasculature: current limitations and future perspective","volume":"36","author":"Iovino","year":"2022","journal-title":"Eye (Lond)"},{"issue":"2","key":"10.1016\/j.aopr.2025.12.002_bib8","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.ophtha.2016.10.003","article-title":"Optical coherence tomography angiography characteristics of Iris melanocytic tumors","volume":"124","author":"Skalet","year":"2017","journal-title":"Ophthalmology"},{"key":"10.1016\/j.aopr.2025.12.002_bib9","article-title":"Advances in application of swept-source optical coherence tomography angiography in diagnosis and treatment of diabetic retinopathy","volume":"3","author":"Zhang","year":"2023","journal-title":"Front Ophthalmol (Lausanne)"},{"key":"10.1016\/j.aopr.2025.12.002_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2024.101246","article-title":"Optic neuropathy in high myopia: glaucoma or high myopia or both?","volume":"99","author":"Zhang","year":"2024","journal-title":"Prog Retin Eye Res"},{"issue":"5","key":"10.1016\/j.aopr.2025.12.002_bib14","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","article-title":"Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050","volume":"123","author":"Holden","year":"2016","journal-title":"Ophthalmology"},{"issue":"4","key":"10.1016\/j.aopr.2025.12.002_bib15","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1167\/iovs.61.4.49","article-title":"The complications of myopia: a review and meta-analysis","volume":"61","author":"Haarman","year":"2020","journal-title":"Investig Ophthalmol Vis Sci"},{"issue":"9","key":"10.1016\/j.aopr.2025.12.002_bib10","doi-asserted-by":"crossref","first-page":"3123","DOI":"10.1007\/s00417-022-05632-7","article-title":"Quantitative changes in iris vasculature and blood flow in patients with different refractive errors","volume":"260","author":"Jia","year":"2022","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"5","key":"10.1016\/j.aopr.2025.12.002_bib16","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1136\/bjophthalmol-2020-317632","article-title":"Quantitative OCT angiography of the retinal microvasculature and choriocapillaris in highly myopic eyes with myopic macular degeneration","volume":"106","author":"Zheng","year":"2022","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"10.1016\/j.aopr.2025.12.002_bib17","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s40662-024-00398-x","article-title":"Choroidal vascular changes in early-stage myopic maculopathy from deep learning choroidal analysis: a hospital-based SS-OCT study","volume":"11","author":"Li","year":"2024","journal-title":"Eye Vis (Lond)"},{"issue":"3","key":"10.1016\/j.aopr.2025.12.002_bib18","first-page":"853","article-title":"Color doppler ultrasound analysis of pathological myopia induced changes in retrobulbar blood flow and its relationship with characteristic changes in myopia","volume":"39","author":"Yu","year":"2023","journal-title":"Pakistan J Med Sci"},{"key":"10.1016\/j.aopr.2025.12.002_bib19","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ajo.2016.10.018","article-title":"Retinal microvascular network and microcirculation assessments in high myopia","volume":"174","author":"Li","year":"2017","journal-title":"Am J Ophthalmol"},{"issue":"6","key":"10.1016\/j.aopr.2025.12.002_bib20","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.ophtha.2017.12.005","article-title":"Progression of myopic maculopathy during 18-Year Follow-up","volume":"125","author":"Fang","year":"2018","journal-title":"Ophthalmology"},{"issue":"1","key":"10.1016\/j.aopr.2025.12.002_bib21","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.preteyeres.2010.09.003","article-title":"Metabolic physiology in age related macular degeneration","volume":"30","author":"Stef\u00e1nsson","year":"2011","journal-title":"Prog Retin Eye Res"},{"issue":"8","key":"10.1016\/j.aopr.2025.12.002_bib22","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1016\/j.ophtha.2009.11.003","article-title":"Long-term pattern of progression of myopic maculopathy: a natural history study","volume":"117","author":"Hayashi","year":"2010","journal-title":"Ophthalmology"}],"container-title":["Advances in Ophthalmology Practice and Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667376225000708?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667376225000708?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T20:10:56Z","timestamp":1781640656000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2667376225000708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S2667376225000708"],"URL":"https:\/\/doi.org\/10.1016\/j.aopr.2025.12.002","relation":{},"ISSN":["2667-3762"],"issn-type":[{"value":"2667-3762","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Swept-source OCTA assessment of iris vasculature as a biomarker for myopic macular degeneration severity","name":"articletitle","label":"Article Title"},{"value":"Advances in Ophthalmology Practice and Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aopr.2025.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of Zhejiang University Press.","name":"copyright","label":"Copyright"}]}}