{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T20:09:41Z","timestamp":1793736581286,"version":"4.6.1"},"reference-count":27,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"4","license":[{"start":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T00:00:00Z","timestamp":1580947200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,5,8]],"date-time":"2018-05-08T00:00:00Z","timestamp":1525737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province of China","doi-asserted-by":"publisher","award":["Y17C100002"],"award-info":[{"award-number":["Y17C100002"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Zhejiang Province Scientifc Project of Health and Medicine of China","award":["2016KYA200"],"award-info":[{"award-number":["2016KYA200"]}]},{"name":"High-level Personnel Training Foundation of Lishui of China","award":["2016RC21"],"award-info":[{"award-number":["2016RC21"]}]},{"name":"Zhejiang Science and Technology Program Foundation of China","award":["2016C33245"],"award-info":[{"award-number":["2016C33245"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["AOTT"],"abstract":"<jats:p>Abstract\n\nObjective\nThis study aimed to conduct a systematic review of literature comparing the clinical effectiveness and safety between anterior reconstruction (AR) and posterior osteotomy (PO) in the treatment of K\u00fcmmell's disease with neurological deficits.\nMethods\nWe systematically reviewed the literature in PubMed, EMBASE, Cochrane Database of Systematic Reviews, and the Web of Science for \u201cspin*,\u201d \u201csurg*,\u201d \u201cK\u00fcmmell's disease,\u201d \u201cKummell's disease,\u201d \u201cKummell disease,\u201d \u201cvertebral osteonecrosis,\u201d \u201cvertebral pseudarthrosis,\u201d \u201cintravertebral vacuum cleft,\u201d \u201cdelayed vertebral collapse,\u201d and \u201ccompression fracture nonunion\u201d. Quality was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation method.\nResults\nA total of 10 publications involving 268 K\u00fcmmell's disease patients with neurological deficits were included in this review, with 7 studies of low- or very low-quality. There were 37.7% and 62.3% of patients receiving AR and PO, respectively. For clinical outcomes, AR group showed no significant differences in pain, neurological dysfunction, and imaging outcome improvements compared with patients who underwent PO. However, the incidence of implant-related complications including loose screw, screw fracture, screw disconnection, and plate dislodgment, was higher in AR group compared with PO group (21.6% vs. 14.3%). As another major complication, AR group more often required a second surgery.\nConclusion\nThis systematic review demonstrated that both AR and PO could improve pain, neurological dysfunction and imaging outcomes. However, serious comorbidities, multilevel corpectomies and\/or severe osteoporosis highly required PO. Design discrepancies were found in the current studies, further higher-quality studies are warranted.\nLevel of evidence\nLevel III, therapeutic study.\nER -<\/jats:p>","DOI":"10.1016\/j.aott.2018.05.002","type":"journal-article","created":{"date-parts":[[2018,5,23]],"date-time":"2018-05-23T22:10:51Z","timestamp":1527113451000},"page":"283-288","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Anterior reconstruction versus posterior osteotomy in treating K\u00fcmmell's disease with neurological deficits: A systematic review"],"prefix":"10.5152","volume":"52","author":[{"given":"Feijun","family":"L\u0130U","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenzhong","family":"CHEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"LOU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyang","family":"YU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"ZHENG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dengwei","family":"HE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kejun","family":"ZHU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3111","published-online":{"date-parts":[[2020,2,6]]},"reference":[{"issue":"2","key":"10.1016\/j.aott.2018.05.002_bib1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0002-9610(51)90206-1","article-title":"Kummell's 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intraosseous vacuum phenomena","volume":"180","author":"Peh","year":"2003","journal-title":"AJR Am J Roentgenol"},{"issue":"7","key":"10.1016\/j.aott.2018.05.002_bib5","doi-asserted-by":"crossref","first-page":"479","DOI":"10.3928\/01477447-20100526-07","article-title":"Kyphoplasty for the Treatment of K\u00fcmmell's Disease","volume":"33","author":"Yang","year":"2010","journal-title":"Orthopedics"},{"issue":"4","key":"10.1016\/j.aott.2018.05.002_bib6","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s00586-012-2508-4","article-title":"Surgical patterns in osteoporotic vertebral compression fractures","volume":"22","author":"Patil","year":"2013","journal-title":"Eur Spine J"},{"issue":"2","key":"10.1016\/j.aott.2018.05.002_bib7","doi-asserted-by":"crossref","first-page":"517","DOI":"10.3892\/etm.2012.833","article-title":"Posterior decompression and short segmental pedicle screw fixation combined with vertebroplasty for Kummell's disease with neurological 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Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}