{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T03:30:21Z","timestamp":1780630221088,"version":"3.54.1"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Physical Medicine and Rehabilitation"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1016\/j.apmr.2004.02.009","type":"journal-article","created":{"date-parts":[[2005,2,8]],"date-time":"2005-02-08T15:14:38Z","timestamp":1107875678000},"page":"312-317","source":"Crossref","is-referenced-by-count":80,"title":["Inflammatory C-reactive protein and cytokine levels in asymptomatic people with chronic spinal cord injury"],"prefix":"10.1016","volume":"86","author":[{"given":"Frederick","family":"Frost","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Jo","family":"Roach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irving","family":"Kushner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Schreiber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.apmr.2004.02.009_bib1","series-title":"Renal failure in paraplegia","first-page":"13","author":"Tribe","year":"1969"},{"key":"10.1016\/j.apmr.2004.02.009_bib2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/sc.1984.9","article-title":"Renal pathology in end-stage renal disease associated with paraplegia","volume":"22","author":"Barton","year":"1984","journal-title":"Paraplegia"},{"key":"10.1016\/j.apmr.2004.02.009_bib3","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1001\/archinte.1989.00390080043011","article-title":"Cause of death for patients with spinal cord injuries","volume":"149","author":"DeVivo","year":"1989","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.apmr.2004.02.009_bib4","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/10790268.2000.11753518","article-title":"Known and plausible modulators of depressed immune functions following spinal cord injuries","volume":"23","author":"Nash","year":"2000","journal-title":"J Spinal Cord Med"},{"key":"10.1016\/j.apmr.2004.02.009_bib5","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1080\/10790268.2000.11753519","article-title":"Influence of neurological level on immune function following spinal cord injury","volume":"23","author":"Campagnolo","year":"2000","journal-title":"J Spinal Cord Med"},{"key":"10.1016\/j.apmr.2004.02.009_bib6","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1080\/01952307.1993.11735881","article-title":"Circulating levels of soluble interleukin 2 receptors are elevated in the sera of humans with spinal cord injury","volume":"16","author":"Segal","year":"1993","journal-title":"J Am Paraplegia Soc"},{"key":"10.1016\/j.apmr.2004.02.009_bib7","first-page":"335","article-title":"Proteins of the complement system and acute phase reactants in sera of patients with spinal cord injury","volume":"66","author":"Rebhun","year":"1991","journal-title":"Ann Allergy"},{"key":"10.1016\/j.apmr.2004.02.009_bib8","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/sc.1996.14","article-title":"Restoration of depressed immune function in spinal cord injury patients receiving rehabilitation therapy","volume":"34","author":"Kliesch","year":"1996","journal-title":"Paraplegia"},{"key":"10.1016\/j.apmr.2004.02.009_bib9","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S0003-9993(97)90008-3","article-title":"Circulating levels of IL-2R, ICAM-1, and IL-6 in spinal cord injuries","volume":"78","author":"Segal","year":"1997","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2004.02.009_bib10","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1056\/NEJM199902113400607","article-title":"Acute phase proteins and other systemic responses to inflammation","volume":"340","author":"Gabay","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.apmr.2004.02.009_bib11","first-page":"89","article-title":"Pressure ulcers","volume":"112","author":"Shea","year":"1975","journal-title":"Clin Orthop"},{"key":"10.1016\/j.apmr.2004.02.009_bib12","series-title":"Manual of clinical immunology","first-page":"942","article-title":"Cytokine testing in clinical trial monitoring","author":"Rossio","year":"1992"},{"key":"10.1016\/j.apmr.2004.02.009_bib13","series-title":"International standards for neurological classification of spinal cord injury","year":"2002"},{"key":"10.1016\/j.apmr.2004.02.009_bib14","first-page":"123","article-title":"Molecular biology of the acute phase plasma proteins","volume":"Vol 14","author":"Gitlin","year":"1987"},{"key":"10.1016\/j.apmr.2004.02.009_bib15","series-title":"Arthritis and allied conditions","first-page":"505","article-title":"Acute phase proteins in rheumatic disease","author":"Volanakis","year":"1997"},{"key":"10.1016\/j.apmr.2004.02.009_bib16","first-page":"425","article-title":"Interrelationship of outcome measures and process variables in early rheumatoid arthritis. A comparison of radiologic damage, physical disability, joint counts, and acute phase reactants","volume":"21","author":"van Leeuwen","year":"1994","journal-title":"J Rheumatol"},{"key":"10.1016\/j.apmr.2004.02.009_bib17","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/clinchem\/43.1.52","article-title":"Variability in the measurement of C-reactive protein in healthy subjects","volume":"43","author":"Macy","year":"1997","journal-title":"Clin Chem"},{"key":"10.1016\/j.apmr.2004.02.009_bib18","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1172\/JCI116319","article-title":"Identification of haptoglobin as an angiogenic factor in sera from patients with systemic vasculitis","volume":"91","author":"Cid","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1016\/j.apmr.2004.02.009_bib19","series-title":"Harrison\u2019s principles of internal medicine","first-page":"1753","author":"Haynes","year":"1998"},{"key":"10.1016\/j.apmr.2004.02.009_bib20","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/stem.5530130105","article-title":"Pathogenesis of the anemia of chronic disease","volume":"13","author":"Means","year":"1995","journal-title":"Stem Cells"},{"key":"10.1016\/j.apmr.2004.02.009_bib21","doi-asserted-by":"crossref","first-page":"420","DOI":"10.4049\/jimmunol.158.1.420","article-title":"Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13","volume":"158","author":"Weiss","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/j.apmr.2004.02.009_bib22","doi-asserted-by":"crossref","first-page":"2740","DOI":"10.1182\/blood.V80.11.2740.2740","article-title":"In vivo effects of interleukin-6 on thrombopoiesis in healthy and irradiated primates","volume":"80","author":"Zeidler","year":"1992","journal-title":"Blood"},{"key":"10.1016\/j.apmr.2004.02.009_bib23","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/00003246-199601000-00026","article-title":"Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome","volume":"24","author":"Bone","year":"1996","journal-title":"Crit Care Med"},{"key":"10.1016\/j.apmr.2004.02.009_bib24","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1089\/10799900152547867","article-title":"Interleukin-6 treatment augments cutaneous wound healing in immunosuppressed mice","volume":"21","author":"Gallucci","year":"2001","journal-title":"J Interferon Cytokine Res"},{"key":"10.1016\/j.apmr.2004.02.009_bib25","first-page":"1273","article-title":"Extension of the life span of pressure ulcer fibroblasts with recombinant human interleukin-1 beta","volume":"146","author":"Vande Berg","year":"1995","journal-title":"Am J Pathol"},{"key":"10.1016\/j.apmr.2004.02.009_bib26","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0301-0082(99)00017-9","article-title":"Trophic effects of purines in neurons and glial cells","volume":"59","author":"Rathbone","year":"1999","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.apmr.2004.02.009_bib27","doi-asserted-by":"crossref","first-page":"7313","DOI":"10.1016\/S0021-9258(20)89445-9","article-title":"Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions","volume":"266","author":"Vilcek","year":"1991","journal-title":"J Biol Chem"},{"key":"10.1016\/j.apmr.2004.02.009_bib28","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1056\/NEJM200103083441001","article-title":"Efficacy and safety of recombinant human activated protein C for severe sepsis","volume":"344","author":"Bernard","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.apmr.2004.02.009_bib29","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0167-5699(97)01118-3","article-title":"Taming TNF","volume":"18","author":"Eigler","year":"1997","journal-title":"Immunol Today"},{"key":"10.1016\/j.apmr.2004.02.009_bib30","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1194\/jlr.M100388-JLR200","article-title":"Promoting export of macrophage cholesterol","volume":"43","author":"Tam","year":"2002","journal-title":"J Lipid Res"},{"key":"10.1016\/j.apmr.2004.02.009_bib31","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3949\/ccjm.68.6.535","article-title":"C-reactive protein elevation can be caused by conditions other than inflammation and may reflect biologic aging","volume":"68","author":"Kushner","year":"2001","journal-title":"Cleve Clin J Med"},{"key":"10.1016\/j.apmr.2004.02.009_bib32","doi-asserted-by":"crossref","first-page":"H1015","DOI":"10.1152\/ajpheart.2000.279.3.H1015","article-title":"The female reproductive cycle is an important variable in the response to trauma-hemorrhage","volume":"279","author":"Jarrar","year":"2000","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.apmr.2004.02.009_bib33","first-page":"2351","article-title":"The influence of age, sex, and race on the upper reference limit of serum C-reactive protein concentration","volume":"27","author":"Wener","year":"2000","journal-title":"J Rheumatol"},{"key":"10.1016\/j.apmr.2004.02.009_bib34","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/S0003-9993(23)00010-2","article-title":"Pressure ulcers in community resident persons with spinal cord injury","volume":"74","author":"Fuhrer","year":"1993","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2004.02.009_bib35","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/S0003-9993(97)90063-0","article-title":"Comparison of long-term renal function after spinal cord injury using different urinary management methods","volume":"78","author":"Sekar","year":"1997","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2004.02.009_bib36","series-title":"Acute phase proteins","first-page":"604","article-title":"Cytokine measurements in disease","author":"Heney","year":"1993"},{"key":"10.1016\/j.apmr.2004.02.009_bib37","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S1359-6101(98)00016-1","article-title":"Semantics, inflammation, cytokines and common sense","volume":"9","author":"Kushner","year":"1998","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.apmr.2004.02.009_bib38","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1093\/infdis\/162.6.1277","article-title":"Adverse effects of aspirin acetaminophen, and ibuprofen on immune function, viral shedding and clinical status in rhinovirus-infected volunteers","volume":"162","author":"Graham","year":"1990","journal-title":"J Infect Dis"}],"container-title":["Archives of Physical Medicine and Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003999304003041?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003999304003041?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T02:36:11Z","timestamp":1682994971000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003999304003041"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S0003999304003041"],"URL":"https:\/\/doi.org\/10.1016\/j.apmr.2004.02.009","relation":{},"ISSN":["0003-9993"],"issn-type":[{"value":"0003-9993","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]}}}