{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:34:22Z","timestamp":1763746462002,"version":"build-2065373602"},"reference-count":49,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100006663","name":"National Institute on Disability and Rehabilitation Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002401","name":"Wilson Reaserch Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002401","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["archives-pmr.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Physical Medicine and Rehabilitation"],"published-print":{"date-parts":[[2005,9]]},"DOI":"10.1016\/j.apmr.2005.03.027","type":"journal-article","created":{"date-parts":[[2005,9,22]],"date-time":"2005-09-22T07:21:12Z","timestamp":1127373672000},"page":"1801-1806","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Comparison of Clinical and Neurophysiologic Responses to Intrathecal Baclofen Bolus Administration in Moderate-to-Severe Spasticity After Acquired Brain Injury"],"prefix":"10.1016","volume":"86","author":[{"given":"Dobrivoje S.","family":"Stokic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart A.","family":"Yablon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Hayes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.apmr.2005.03.027_bib1","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1093\/ptj\/75.5.352","article-title":"The effects of intrathecally administered baclofen on function in patients with spasticity","volume":"75","author":"Campbell","year":"1995","journal-title":"Phys Ther"},{"key":"10.1016\/j.apmr.2005.03.027_bib2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/154596839901300103","article-title":"Therapeutics in the management of spasticity","volume":"13","author":"Gelber","year":"1999","journal-title":"Neurorehabil Neural Repair"},{"key":"10.1016\/j.apmr.2005.03.027_bib3","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/S1047-9651(18)30039-1","article-title":"Intrathecal baclofen therapy for spastic hypertonia","volume":"12","author":"Ivanhoe","year":"2001","journal-title":"Phys Med Rehabil Clin North Am"},{"key":"10.1016\/j.apmr.2005.03.027_bib4","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1056\/NEJM198906083202310","article-title":"Treatment of spastic paresis","volume":"320","author":"Young","year":"1989","journal-title":"N Engl J Med"},{"issue":"Suppl 1","key":"10.1016\/j.apmr.2005.03.027_bib5","doi-asserted-by":"crossref","first-page":"S29","DOI":"10.1177\/0883073896011001S05","article-title":"Intrathecal baclofen in cerebral palsy movement disorders","volume":"11","author":"Albright","year":"1996","journal-title":"J Child Neurol"},{"key":"10.1016\/j.apmr.2005.03.027_bib6","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1001\/jama.1993.03510200081036","article-title":"Continuous intrathecal baclofen infusion for spasticity of cerebral origin","volume":"270","author":"Albright","year":"1993","journal-title":"JAMA"},{"key":"10.1016\/j.apmr.2005.03.027_bib7","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3171\/jns.2003.98.2.0291","article-title":"Long-term intrathecal baclofen therapy for severe spasticity of cerebral origin","volume":"98","author":"Albright","year":"2003","journal-title":"J Neurosurg"},{"key":"10.1016\/j.apmr.2005.03.027_bib8","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1161\/hs0901.095682","article-title":"Intrathecal baclofen for spastic hypertonia from stroke","volume":"32","author":"Meythaler","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.apmr.2005.03.027_bib9","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1034\/j.1600-0404.2002.1o042.x","article-title":"Long-term intrathecal baclofen infusion in supraspinal spasticity of adulthood","volume":"105","author":"Dario","year":"2002","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.apmr.2005.03.027_bib10","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1177\/088307380001500201","article-title":"Intrathecal baclofen for management of spastic cerebral palsy","volume":"15","author":"Gilmartin","year":"2000","journal-title":"J Child Neurol"},{"key":"10.1016\/j.apmr.2005.03.027_bib11","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1053\/apmr.2002.36068","article-title":"Intrathecal baclofen therapy in children with cerebral palsy","volume":"83","author":"Murphy","year":"2002","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2005.03.027_bib12","first-page":"29","article-title":"Intrathecal baclofen application in patients with supraspinal spasticity secondary to severe traumatic brain injury","volume":"9","author":"Rifici","year":"1994","journal-title":"Funct Neurol"},{"key":"10.1016\/j.apmr.2005.03.027_bib13","doi-asserted-by":"crossref","first-page":"733","DOI":"10.3171\/jns.1999.91.5.0733","article-title":"Treatment of cerebral origin spasticity with continuous intrathecal baclofen delivered via an implantable pump","volume":"91","author":"Rawicki","year":"1999","journal-title":"J Neurosurg"},{"key":"10.1016\/j.apmr.2005.03.027_bib14","article-title":"Intrathecal baclofen therapy for spasticity of cerebral origin","author":"Albright","year":"1997","journal-title":"Medtronic"},{"key":"10.1016\/j.apmr.2005.03.027_bib15","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1136\/jnnp.52.9.1110","article-title":"Intrathecal baclofen and the H-reflex","volume":"52","author":"Macdonell","year":"1989","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.apmr.2005.03.027_bib16","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0924-980X(96)96555-8","article-title":"Clinical use of polysynaptic flexion reflexes in the management of spasticity with intrathecal baclofen","volume":"105","author":"Parise","year":"1997","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2005.03.027_bib17","first-page":"77","article-title":"Neurophysiological and clinical evaluation of intrathecal baclofen bolus trial in acquired brain injury [abstract]","volume":"14","author":"Stokic","year":"2000","journal-title":"Neurorehabil Neural Repair"},{"key":"10.1016\/j.apmr.2005.03.027_bib18","first-page":"327","article-title":"The utility of H-reflex for monitoring the delivery of continuous intrathecal baclofen (ITB) in patients with dysfunctional spasticity","volume":"15","author":"Stokic","year":"2001","journal-title":"Repeatability and dose-response relationship [abstract]. Neurorehabil Neural Repair"},{"key":"10.1016\/j.apmr.2005.03.027_bib19","first-page":"540","article-title":"Preliminary trial of carisoprodol in multiple sclerosis","volume":"192","author":"Ashworth","year":"1964","journal-title":"Practitioner"},{"key":"10.1016\/j.apmr.2005.03.027_bib20","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/00002060-199905000-00012","article-title":"Continuously infused intrathecal baclofen for spastic\/dystonic hemiplegia","volume":"78","author":"Meythaler","year":"1999","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2005.03.027_bib21","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1007\/s00415-003-0178-1","article-title":"Time course of the effect of a bolus dose of intrathecal baclofen on severe cerebral spasticity","volume":"250","author":"Pohl","year":"2003","journal-title":"J Neurol"},{"key":"10.1016\/j.apmr.2005.03.027_bib22","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1191\/0269215503cr610oa","article-title":"A biomechanical investigation into the validity of the modified Ashworth Scale as a measure of elbow spasticity","volume":"17","author":"Pandyan","year":"2003","journal-title":"Clin Rehabil"},{"key":"10.1016\/j.apmr.2005.03.027_bib23","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0014-4886(89)90078-2","article-title":"Short-term effects of intrathecal baclofen in spasticity","volume":"103","author":"Latash","year":"1989","journal-title":"Exp Neurol"},{"key":"10.1016\/j.apmr.2005.03.027_bib24","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1136\/jnnp.56.5.515","article-title":"Effect of intrathecal baclofen on the monosynaptic reflex in humans","volume":"56","author":"Azouvi","year":"1993","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.apmr.2005.03.027_bib25","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/S1388-2457(02)00010-X","article-title":"Electrophysiological assessment of the effect of intrathecal baclofen in spastic children","volume":"113","author":"Dachy","year":"2002","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2005.03.027_bib26","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1001\/archneur.1963.00460060021002","article-title":"The H reflex in normal, spastic and rigid subjects","volume":"8","author":"Angel","year":"1963","journal-title":"Arch Neurol"},{"key":"10.1016\/j.apmr.2005.03.027_bib27","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1136\/jnnp.56.7.776","article-title":"Soleus H-reflex tests and clinical signs of the upper motor neuron syndrome","volume":"56","author":"Koelman","year":"1993","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.apmr.2005.03.027_bib28","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1136\/jnnp.74.5.646","article-title":"The relation between Ashworth Scale scores and the excitability of the motor neurones in patients with post-stroke muscle spasticity","volume":"74","author":"Bakheit","year":"2003","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.apmr.2005.03.027_bib29","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1002\/mds.870100109","article-title":"Soleus H-reflex tests in dystonia","volume":"10","author":"Koelman","year":"1995","journal-title":"Mov Disord"},{"key":"10.1016\/j.apmr.2005.03.027_bib30","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S1388-2457(02)00375-9","article-title":"Soleus H-reflex measures in patients with focal and generalized dystonia","volume":"114","author":"Sabbahi","year":"2003","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2005.03.027_bib31","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0003-9993(92)90007-J","article-title":"Objective quantification of spastic hypertonia","volume":"73","author":"Katz","year":"1992","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2005.03.027_bib32","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/BF00858718","article-title":"Are H and stretch reflexes in hemiparesis reproducible and correlated with spasticity?","volume":"240","author":"Levin","year":"1993","journal-title":"J Neurol"},{"key":"10.1016\/j.apmr.2005.03.027_bib33","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/S1388-2457(00)00289-3","article-title":"Quantitative measures of spasticity in post-stroke patients","volume":"111","author":"Pisano","year":"2000","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2005.03.027_bib34","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1177\/135245859600100506","article-title":"A comparison of clinical and laboratory measures of spasticity","volume":"1","author":"Nielsen","year":"1996","journal-title":"Mult Scler"},{"key":"10.1016\/j.apmr.2005.03.027_bib35","first-page":"233","article-title":"The mechanism of spastic muscle hypertonus. Variation in reflex gain over the time course of spasticity","volume":"114","author":"Thilmann","year":"1991","journal-title":"Brain"},{"key":"10.1016\/j.apmr.2005.03.027_bib36","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1093\/brain\/117.2.355","article-title":"Passive, intrinsic and reflex-mediated stiffness in the ankle extensors of hemiparetic patients","volume":"117","author":"Sinkjaer","year":"1994","journal-title":"Brain"},{"key":"10.1016\/j.apmr.2005.03.027_bib37","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1007\/s004150050516","article-title":"Measurement of the effect of a bolus dose of intrathecal baclofen by a repetitive movement test","volume":"246","author":"Becher","year":"1999","journal-title":"J Neurol"},{"key":"10.1016\/j.apmr.2005.03.027_bib38","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0003-9993(00)90071-6","article-title":"Quantitative assessment of intrathecally administered baclofen in spasticity","volume":"81","author":"Detrembleur","year":"2000","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2005.03.027_bib39","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1179\/108331902125001770","article-title":"Ashworth and Tardieu scales","volume":"7","author":"Morris","year":"2002","journal-title":"Phys Ther Rev"},{"key":"10.1016\/j.apmr.2005.03.027_bib40","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1191\/026921599677595404","article-title":"A review of the properties and limitations of the Ashworth and modified Ashworth Scales as measures of spasticity","volume":"13","author":"Pandyan","year":"1999","journal-title":"Clin Rehabil"},{"issue":"Suppl 2","key":"10.1016\/j.apmr.2005.03.027_bib41","first-page":"S41","article-title":"Spasticity measurement in stroke","volume":"83","author":"Harburn","year":"1992","journal-title":"Can J Public Health"},{"key":"10.1016\/j.apmr.2005.03.027_bib42","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1212\/WNL.29.9_Part_1.1306","article-title":"Amplitude of the F wave","volume":"29","author":"Eisen","year":"1979","journal-title":"Neurology"},{"key":"10.1016\/j.apmr.2005.03.027_bib43","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0022-510X(83)90186-7","article-title":"F response analysis of motor disorders of central origin","volume":"62","author":"Fisher","year":"1983","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.apmr.2005.03.027_bib44","first-page":"11","article-title":"F-wave for assessment of segmental motoneurone excitability","volume":"32","author":"Milanov","year":"1992","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2005.03.027_bib45","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1600-0404.1992.tb04048.x","article-title":"Mechanisms of baclofen action on spasticity","volume":"85","author":"Milanov","year":"1992","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.apmr.2005.03.027_bib46","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/mus.880180114","article-title":"Influence of baclofen upon the alpha-motoneuron in spasticity by means of F-wave analysis","volume":"18","author":"Dressnandt","year":"1995","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.apmr.2005.03.027_bib47","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1136\/jnnp.41.1.45","article-title":"F responses studied with single fibre EMG in normal subjects and spastic patients","volume":"41","author":"Schiller","year":"1978","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.apmr.2005.03.027_bib48","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/00004356-199603000-00007","article-title":"Reliability of the modified Ashworth Scale in the assessment of plantarflexor muscle spasticity in patients with traumatic brain injury","volume":"19","author":"Allison","year":"1996","journal-title":"Int J Rehabil Res"},{"issue":"10 Suppl","key":"10.1016\/j.apmr.2005.03.027_bib49","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1097\/01.PHM.0000141126.11008.7D","article-title":"Neurophysiologic evaluation of spastic hypertonia","volume":"83","author":"Yablon","year":"2004","journal-title":"Am J Phys Med Rehabil"}],"container-title":["Archives of Physical Medicine and Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003999305003333?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003999305003333?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T13:14:38Z","timestamp":1762089278000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003999305003333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9]]},"references-count":49,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2005,9]]}},"alternative-id":["S0003999305003333"],"URL":"https:\/\/doi.org\/10.1016\/j.apmr.2005.03.027","relation":{},"ISSN":["0003-9993"],"issn-type":[{"type":"print","value":"0003-9993"}],"subject":[],"published":{"date-parts":[[2005,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of Clinical and Neurophysiologic Responses to Intrathecal Baclofen Bolus Administration in Moderate-to-Severe Spasticity After Acquired Brain Injury","name":"articletitle","label":"Article Title"},{"value":"Archives of Physical Medicine and Rehabilitation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.apmr.2005.03.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}