{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T04:52:32Z","timestamp":1767675152514},"reference-count":34,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Physical Medicine and Rehabilitation"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1016\/j.apmr.2010.04.023","type":"journal-article","created":{"date-parts":[[2010,8,3]],"date-time":"2010-08-03T08:42:52Z","timestamp":1280824972000},"page":"1160-1165","source":"Crossref","is-referenced-by-count":24,"title":["Quantification of the Effects of Transcutaneous Electrical Nerve Stimulation With Functional Magnetic Resonance Imaging: A Double-Blind Randomized Placebo-Controlled Study"],"prefix":"10.1016","volume":"91","author":[{"given":"Murat","family":"Kara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Levent","family":"\u00d6z\u00e7akar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didem","family":"G\u00f6k\u00e7ay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erol","family":"\u00d6z\u00e7elik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Y\u00f6r\u00fcbulut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sinem","family":"G\u00fcneri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bayram","family":"Kaymak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u015fen","family":"Ak\u0131nc\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alp","family":"\u00c7etin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.apmr.2010.04.023_bib1","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1126\/science.150.3699.971","article-title":"Pain mechanisms: a new theory","volume":"150","author":"Melzack","year":"1965","journal-title":"Science"},{"key":"10.1016\/j.apmr.2010.04.023_bib2","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.ejpain.2004.11.001","article-title":"Human brain mechanisms of pain perception and regulation in health and disease","volume":"9","author":"Apkarian","year":"2005","journal-title":"Eur J Pain"},{"key":"10.1016\/j.apmr.2010.04.023_bib3","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1002\/(SICI)1097-4598(199712)20:12<1477::AID-MUS1>3.0.CO;2-5","article-title":"AAEM minimonograph 26: the electrodiagnosis of carpal tunnel syndrome","volume":"20","author":"Stevens","year":"1997","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.apmr.2010.04.023_bib4","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.2106\/00004623-199311000-00002","article-title":"A self-administered questionnaire for the assessment of severity of symptoms and functional status in carpal tunnel syndrome","volume":"75","author":"Levine","year":"1993","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.apmr.2010.04.023_bib5","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1080\/09638280600621469","article-title":"Assessment of symptom severity and functional status in patients with carpal tunnel syndrome: reliability and functionality of the Turkish version of the Boston Questionnaire","volume":"28","author":"Sezgin","year":"2006","journal-title":"Disabil Rehabil"},{"key":"10.1016\/j.apmr.2010.04.023_bib6","first-page":"1495","article-title":"A self-administred hand symptom diagram for the diagnosis and epidemiologic study of carpal tunnel syndrome","volume":"17","author":"Katz","year":"1990","journal-title":"J Rheumatol"},{"key":"10.1016\/j.apmr.2010.04.023_bib7","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s00776-003-0684-0","article-title":"Objective evaluation of sensory function in patients with carpal tunnel syndrome using the current perception threshold","volume":"8","author":"Nishimura","year":"2003","journal-title":"J Orthop Sci"},{"key":"10.1016\/j.apmr.2010.04.023_bib8","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1006\/cbmr.1996.0014","article-title":"AFNI: software for analysis and visualization of functional magnetic resonance neuroimages","volume":"29","author":"Cox","year":"1996","journal-title":"Comput Biomed Res"},{"year":"1988","series-title":"Co-palanar stereotaxic atlas of the human brain","author":"Talairach","key":"10.1016\/j.apmr.2010.04.023_bib9"},{"key":"10.1016\/j.apmr.2010.04.023_bib10","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1002\/mrm.1910330508","article-title":"Improved assessment of significant activation in functional magnetic resonance imaging (fMRI): use of a cluster-size threshold","volume":"33","author":"Forman","year":"1995","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.apmr.2010.04.023_bib11","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1054\/jpai.2003.434","article-title":"TENS basic science mechanisms and clinical effectiveness","volume":"4","author":"Kathleen","year":"2003","journal-title":"J Pain"},{"issue":"2","key":"10.1016\/j.apmr.2010.04.023_bib12","article-title":"Transcutaneous electrical nerve stimulation (TENS) for chronic low back pain","author":"Milne","year":"2001","journal-title":"Cochrane Data Base Syst Rev"},{"key":"10.1016\/j.apmr.2010.04.023_bib13","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1093\/ptj\/68.11.1694","article-title":"Selected problems in the use of transcutaneous electrical nerve stimulation for pain control: an appraisal with proposed solutions: a special communication","volume":"68","author":"Nolan","year":"1998","journal-title":"Phys Ther"},{"key":"10.1016\/j.apmr.2010.04.023_bib14","doi-asserted-by":"crossref","first-page":"208","DOI":"10.2519\/jospt.1996.24.4.208","article-title":"Transcutaneous electrical nerve stimulation for the control of pain in musculoskeletal disorders","volume":"24","author":"Robinson","year":"1996","journal-title":"J Orthop Sports Phys Ther"},{"key":"10.1016\/j.apmr.2010.04.023_bib15","series-title":"Physical medicine and rehabilitation","first-page":"464","article-title":"Electrical stimulation","author":"Mysiw","year":"1996"},{"key":"10.1016\/j.apmr.2010.04.023_bib16","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.neulet.2003.10.045","article-title":"Short-term high-frequency TENS decreases human motor cortex excitability","volume":"355","author":"Mima","year":"2004","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.apmr.2010.04.023_bib17","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s00221-004-2091-y","article-title":"Long-lasting modulation of human motor cortex following prolonged TENS of forearm muscles: evidence of reciprocal inhibition and facilitation","volume":"161","author":"Tinazzi","year":"2005","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.apmr.2010.04.023_bib18","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/0963828021000007978","article-title":"A review of treatment for carpal tunnel syndrome","volume":"25","author":"Wilson","year":"2003","journal-title":"Disabil Rehabil"},{"key":"10.1016\/j.apmr.2010.04.023_bib19","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1053\/jhsu.2001.24972","article-title":"The prevalence and characteristics of nerve compression symptoms in the general population","volume":"26","author":"Papanicolaou","year":"2001","journal-title":"J Hand Surg Am"},{"key":"10.1016\/j.apmr.2010.04.023_bib20","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.jphysparis.2005.09.019","article-title":"self-regulation of local brain activity using real-time functional resonance imaging (fMRI)","volume":"98","author":"Weiskopf","year":"2004","journal-title":"J Physiol Paris"},{"key":"10.1016\/j.apmr.2010.04.023_bib21","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.bbr.2008.04.020","article-title":"A combined [11C] diprenorphine PET study and fMRI study of acupuncture analgesia","volume":"193","author":"Dougherty","year":"2008","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.apmr.2010.04.023_bib22","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1097\/00000542-200412000-00021","article-title":"Chronic oral gabapentin reduces elements of central sensitization in human experimental hyperalgesia","volume":"101","author":"Gottrup","year":"2004","journal-title":"Anesthesiology"},{"key":"10.1016\/j.apmr.2010.04.023_bib23","doi-asserted-by":"crossref","first-page":"18195","DOI":"10.1073\/pnas.0506624102","article-title":"Pharmacological modulation of pain-related brain activity during normal and central sensitization states in humans","volume":"102","author":"Iannetti","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.apmr.2010.04.023_bib24","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/hbm.20261","article-title":"Somatosensory cortical plasticity in carpal tunnel syndrome treated by acupuncture","volume":"28","author":"Napadow","year":"2007","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.apmr.2010.04.023_bib25","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S0006-8993(03)02983-4","article-title":"Relations between brain network activation and analgesic effect induced by low vs. high frequency electrical acupoint stimulation in different subjects: a functional magnetic resonance imaging study","volume":"982","author":"Zhang","year":"2003","journal-title":"Brain Res"},{"key":"10.1016\/j.apmr.2010.04.023_bib26","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.neuroimage.2005.12.017","article-title":"Somatosensory cortical plasticity in carpal tunnel syndrome\u2014a cross-sectional fMRI evaluation","volume":"31","author":"Napadow","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.apmr.2010.04.023_bib27","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S1388-2457(99)00299-0","article-title":"After-effect of transcutaneous electrical nerve stimulation (TENS) on pain-related evoked potentials and magnetic fields in normal subjects","volume":"111","author":"Hoshiyama","year":"2000","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2010.04.023_bib28","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0013-4694(91)90115-K","article-title":"Long-lasting depression of central synaptic transmission following prolonged high-frequency stimulation of cutaneous afferent: a mechanism for postvibratory hypaesthesia","volume":"78","author":"Macefield","year":"1991","journal-title":"Electroenceph Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2010.04.023_bib29","first-page":"1402","article-title":"Functional MR imaging analysis of pain-related brain activation after acute mechanical stimulation","volume":"21","author":"Creach","year":"2000","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.apmr.2010.04.023_bib30","first-page":"69","article-title":"Is there a role for the parietal lobes in the perception of pain?","volume":"93","author":"Duncan","year":"2003","journal-title":"Adv Neurol"},{"key":"10.1016\/j.apmr.2010.04.023_bib31","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0987-7053(00)00227-6","article-title":"Functional imaging of brain responses to pain: a review and meta-analysis","volume":"30","author":"Peyron","year":"2000","journal-title":"Neurophysiol Clin"},{"key":"10.1016\/j.apmr.2010.04.023_bib32","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1016\/j.neuroimage.2006.05.027","article-title":"Predictability modulates the affective and sensory-discriminative neural processing of pain","volume":"32","author":"Carlsson","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.apmr.2010.04.023_bib33","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1093\/brain\/122.9.1765","article-title":"Haemodynamic brain responses to acute pain in humans: sensory and attentional networks","volume":"122","author":"Peyron","year":"1999","journal-title":"Brain"},{"key":"10.1016\/j.apmr.2010.04.023_bib34","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1007\/s11307-007-0086-3","article-title":"Understanding the placebo effect: contributions from neuroimaging","volume":"9","author":"Lidstone","year":"2007","journal-title":"Mol Imaging Biol"}],"container-title":["Archives of Physical Medicine and Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003999310002546?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003999310002546?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T05:04:28Z","timestamp":1549602268000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003999310002546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":34,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["S0003999310002546"],"URL":"https:\/\/doi.org\/10.1016\/j.apmr.2010.04.023","relation":{},"ISSN":["0003-9993"],"issn-type":[{"type":"print","value":"0003-9993"}],"subject":[],"published":{"date-parts":[[2010,8]]}}}